Mrot003557.1
Basic Information
- Insect
- Megachile rotundata
- Gene Symbol
- -
- Assembly
- GCA_000220905.1
- Location
- NW:1098633-1107431[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 16 2.7e-05 0.0017 17.9 0.8 1 23 99 122 99 122 0.94 2 16 0.0096 0.59 9.9 4.6 2 23 250 272 250 272 0.91 3 16 0.00028 0.018 14.7 1.5 2 23 316 338 315 338 0.95 4 16 5.4 3.3e+02 1.3 7.6 3 23 423 444 422 444 0.95 5 16 2.7e-05 0.0017 17.9 0.8 1 23 488 511 488 511 0.94 6 16 0.0096 0.59 9.9 4.6 2 23 639 661 639 661 0.91 7 16 0.00028 0.018 14.7 1.5 2 23 705 727 704 727 0.95 8 16 5.4 3.3e+02 1.3 7.6 3 23 812 833 811 833 0.95 9 16 0.97 60 3.6 2.2 1 23 882 905 882 905 0.93 10 16 0.0011 0.069 12.8 0.4 2 23 955 977 954 977 0.94 11 16 0.00011 0.0068 16.0 0.2 3 23 1000 1021 998 1021 0.93 12 16 0.0071 0.44 10.3 3.6 2 23 1063 1085 1062 1085 0.96 13 16 0.096 5.9 6.8 4.2 3 23 1100 1121 1098 1121 0.92 14 16 0.00024 0.015 14.9 0.1 2 23 1165 1187 1165 1187 0.94 15 16 0.12 7.4 6.5 1.7 1 23 1266 1288 1266 1288 0.98 16 16 0.00044 0.027 14.1 0.6 2 23 1302 1324 1301 1324 0.93
Sequence Information
- Coding Sequence
- ATGGCGAACGAGACGACGACGATATCGGAATTGACGGAATTGGACAGCGATGGATCGAGTTGCGGGGAACGGGACGTCAGGAAACGTCTCCGAGTTGACGCAGATTCGACCGGGCCGAAGAAGAGACGAAAACAGACGACCCCCGTAAGATTCTCGTCCGCGCTGATGATGAGCGGCGTGCACGAGGAATCGAACGAGGACGAGGACGAGGACGAGGACAGCGAAGGTAAGCTGTCGTCGCAGTCACCCATACCGAGTCAATCGTCGATCAGGGACGAGAACCTCAATAACGAATTCCGTTGCCAGTACTGCGGTCAGTTTTTCGATAGCAAGGATACGTTGAACGTTCACCTCGATAACGAGCACGGTTCCGCGAATCAGTCGTCTCAGCAGGGTCAAAGCGGATACTCGAGTAGCGCGATTAAACAGGAACCGTCTCAGCAACTGGACCAAACCGAGACTCCCGTTAATCTGCTTAGCGTGAAGAATTTCGCGATAAATTGGCTGGCTACCGGACAACACGTGCAATCGCACGTGCAAATGCAGCCGCAGAACGAGGACTCGTGGCCGGGCGGTACAGCCAGTCAAATCACCTCGTTGCCCAATCACCTGCAGGTACTCTCTTCCGGTTTCCCTGGTTCCTTGACGCAGTACCTATCTCTGCCCACGTTCCCGTTAACGGACTCCGGTCCGATCGCGAGATCTTCGATAGGACCGACGCCGGTGAGAATCTTTAATCCGGACGCGTACTGCGATCTGTGCAATAAAGAGTTCTGCAACAAGTATTTCCTGAAGACGCACAAGGCGAACAAGCACGGGATCTACGCGGATTCGCCGGGACCCAGCTCGGTAGACAATAACGTCGTAACTCCCATGTACCCCGCTAACTTTTCTAGCAACCTAGTCAAACTGGAACCACCCGCGACGCCACCCACGCCCAGCGTACCCTGCGACCTCTGCCAGAAACGCTTCAAGAACGAGGATTCGATGCGCAAGCACAAACAGAAAATGCACACCGATTTGCCGGATCAGACGCAGGAACCTCAGATCAATCTATCTCAGAACGAGGAGGACACGGAAACACCGAGAAACAATTTCGCGAGCATCGAGTCATTTTTCAAACAGGAATACGGAGTGGAACAGGAGGACGCATCTTTCATGCCTGCGCCTAGACACCTATCTCCCCAGTCGATTCAACAGGCACGGGACTCCGGTTTTAACGCTGATCGGCTTCGACGCTTAGGGGTGATAAATCCGGAGGCGTTTTGCGAGATCTGCTGTAAAGAGTACTGTAACAAGTATTTCCTGCGGACGCATAAAATGAAGAGGCACGGCATCGTCGTTCAAGATAGCGAGAGGTCGCCGGGTAATCCAGGATCAGCGCCCACTTGGCATCAAGTGCAAACTAGCCCGTTAAATTTGTGTCAATCGTCGATCAGGGACGAGAACCTCAATAACGAATTCCGTTGCCAGTACTGCGGTCAGTTTTTCGATAGCAAGGATACGTTGAACGTTCACCTCGATAACGAGCACGGTTCCGCGAATCAGTCGTCTCAGCAGGGTCAAAGCGGATACTCGAGTAGCGCGATTAAACAGGAACCGTCTCAGCAACTGGACCAAACCGAGACTCCCGTTAATCTGCTTAGCGTGAAGAATTTCGCGATAAATTGGCTGGCTACCGGACAACACGTGCAATCGCACGTGCAAATGCAGCCGCAGAACGAGGACTCGTGGCCGGGCGGTACAGCCAGTCAAATCACCTCGTTGCCCAATCACCTGCAGGTACTCTCTTCCGGTTTCCCTGGTTCCTTGACGCAGTACCTATCTCTGCCCACGTTCCCGTTAACGGACTCCGGTCCGATCGCGAGATCTTCGATAGGACCGACGCCGGTGAGAATCTTTAATCCGGACGCGTACTGCGATCTGTGCAATAAAGAGTTCTGCAACAAGTATTTCCTGAAGACGCACAAGGCGAACAAGCACGGGATCTACGCGGATTCGCCGGGACCCAGCTCGGTAGACAATAACGTCGTAACTCCCATGTACCCCGCTAACTTTTCTAGCAACCTAGTCAAACTGGAACCACCCGCGACGCCACCCACGCCCAGCGTACCCTGCGACCTCTGCCAGAAACGCTTCAAGAACGAGGATTCGATGCGCAAGCACAAACAGAAAATGCACACCGATTTGCCGGATCAGACGCAGGAACCTCAGATCAATCTATCTCAGAACGAGGAGGACACGGAAACACCGAGAAACAATTTCGCGAGCATCGAGTCATTTTTCAAACAGGAATACGGAGTGGAACAGGAGGACGCATCTTTCATGCCTGCGCCTAGACACCTATCTCCCCAGTCGATTCAACAGGCACGGGACTCCGGTTTTAACGCTGATCGGCTTCGACGCTTAGGGGTGATAAATCCGGAGGCGTTTTGCGAGATCTGCTGTAAAGAGTACTGTAACAAGTATTTCCTGCGGACGCATAAAATGAAGAGGCACGGCATCGTCGTTCAAGATAGCGAGAGGTCGCCGGGTAATCCAGGATCAGCGCCCACTTGGCATCAAGTGCAAACTAGCCCGTTAAATTTGATCGTCGCGGAGAGCGCCAGCAGCACCGAGTCGAACGAGCGGCCAGGGGACGACTACGAGTGCAAACCCTGCGGAATACGATTCCAGACCATCGATCTTTATCAGACACATTGCCGGAAGATGCACGAGAGCGAGGAGCAACGGTCCCCTAAGCAGGAGTGCGAACTGGAGACACCGACCGACCAGCCGAACGATTCCATCTCGGAGGATCTTCAAAAATTGCAGACGATGCTGTTACAGCTGAACGGACTGAAGTCCAGCAAGCAGGGACTGTCGTGCAACGTGTGCGGAAAGGAATACGACACCAGAACCGCGTTGCACATTCACGCGACGACCGAACACGCGTCCATCCCTGAAGACCCGACCTCGCCGCAGGAAAAGTCACCGTTAACCGCGACGTCCATGTTCTGCACCCTGTGCGGGAAGGACTACGCGAGCCAGGACGCCCTCAGAAGACACATAACGGAGGAACATCAGCCACCGATTATGAACACCCTTCCTCAAACACCGGCAACTACCTCCACCACGACCAACTCGAACGCGACGAGTCAAAGCACCTCCGAGAGGAAGGTGACGTCGATGACGCCCACGTCGAGCTACTGCGAGATATGCAACAAGGAGCTGTGCAATAAGTACTTCATGAAGACCCACATGCAGAGGATGCACGGCATCGAGATCGAGAACGGGGCTCAGATCGGTGGCGTGATATGCAACATCTGTAACAAAGAACTGTGCAGCAAGTACTTCCTACGAGTGCACAAGCATAATACTCATGGAATAGTGGACGAGAACGCGCCCAGTTCGGTGAAACAAGAAGCGCTCGAGGCCACGAACACCGACGACGCCCTGAAGCCGGAGCAACTCGGGGATTTGAGTCACAGGTACTTCACCCACTTTACGGAGGTTTGTCCGATCTGCAGCAGAAGGTTCCGCAGCATAAAGTGGCTGAAGGCTCACTTGATGGGCGAGCACGGGAAAGCGGGCATCGACAAATGGCGCGAGATGGAACAACATTATCAGACAGCGTCAAGAACAACGAACAGGACCACCAGCACTCCGAAGAATACTCAGCAGGGCTCGAACTTGAAGATACCGAACGGATTCGAGATTACGCAGCAACACAAGTCGGCCGACTACACCGGTTTGGGGAACCAAGTGCTGTCTAATTTGCTGGGATCATCCTCCGAGGATCAACAACTGAAGAGCTATCGTTGTTCCTATTGTACGTTCACGACCACCGTGCTGCCGTTCCTCTTTCTTCACGAGAGATCTCACGTGCACTCCCGGGAAAACGCGGAGGGGGAGAAATCACTTCAGTGCCCGATTTGCTCGCAGAGCTTTCATCAGCCCGAGCTGTTGCATCAACATCTACTCGCGGCGCACCAGTTTCCCACGTTGTTGTCCCATTTTCCACCGCCGATGCTGAACAATTTAACACCCGACGCGGAGAAACTGAACGAGGTCAAGGAGAGGCTGGAGCTGGAGACAAAAGAGGATCGTATCGGGAACAGTCCGCAAGTCACTGCCAACAAAAGCGTCCCGGAGCCGATCAGGAATCAACGACAGGACGACACGACGGTTCAAGTCACTCCTCAGGGTGTGTACAAGTGCGCGCAGTGTTGTTACGCCACGACAAACTTGAACAGGATCAAAAAGCACGTCAGAAAGGATCACAGGACCATCGGTGACCCCACCGACAGCGTGATAGCGGAGCTAGGTAGAACACTGAAGGACGTTGCCAACAGACACAAGGTGCCGGCTTGCTACGCGATGCCGCAGGACATGAACTCGAATCCTGACAAAACTATCATGCAACCGTTCCTCATCGAGGAACAGGACGCGATGCAAGCCGGCGAGGAGTCCGGCTCGGATAAACGATTCGCGCCGGCTTTGGTTTATTTACCGGTTAAATCGAGAATCAACAACCCCCTCACCGCATCCTTCACCCTCAGCCCCGCTTGA
- Protein Sequence
- MANETTTISELTELDSDGSSCGERDVRKRLRVDADSTGPKKRRKQTTPVRFSSALMMSGVHEESNEDEDEDEDSEGKLSSQSPIPSQSSIRDENLNNEFRCQYCGQFFDSKDTLNVHLDNEHGSANQSSQQGQSGYSSSAIKQEPSQQLDQTETPVNLLSVKNFAINWLATGQHVQSHVQMQPQNEDSWPGGTASQITSLPNHLQVLSSGFPGSLTQYLSLPTFPLTDSGPIARSSIGPTPVRIFNPDAYCDLCNKEFCNKYFLKTHKANKHGIYADSPGPSSVDNNVVTPMYPANFSSNLVKLEPPATPPTPSVPCDLCQKRFKNEDSMRKHKQKMHTDLPDQTQEPQINLSQNEEDTETPRNNFASIESFFKQEYGVEQEDASFMPAPRHLSPQSIQQARDSGFNADRLRRLGVINPEAFCEICCKEYCNKYFLRTHKMKRHGIVVQDSERSPGNPGSAPTWHQVQTSPLNLCQSSIRDENLNNEFRCQYCGQFFDSKDTLNVHLDNEHGSANQSSQQGQSGYSSSAIKQEPSQQLDQTETPVNLLSVKNFAINWLATGQHVQSHVQMQPQNEDSWPGGTASQITSLPNHLQVLSSGFPGSLTQYLSLPTFPLTDSGPIARSSIGPTPVRIFNPDAYCDLCNKEFCNKYFLKTHKANKHGIYADSPGPSSVDNNVVTPMYPANFSSNLVKLEPPATPPTPSVPCDLCQKRFKNEDSMRKHKQKMHTDLPDQTQEPQINLSQNEEDTETPRNNFASIESFFKQEYGVEQEDASFMPAPRHLSPQSIQQARDSGFNADRLRRLGVINPEAFCEICCKEYCNKYFLRTHKMKRHGIVVQDSERSPGNPGSAPTWHQVQTSPLNLIVAESASSTESNERPGDDYECKPCGIRFQTIDLYQTHCRKMHESEEQRSPKQECELETPTDQPNDSISEDLQKLQTMLLQLNGLKSSKQGLSCNVCGKEYDTRTALHIHATTEHASIPEDPTSPQEKSPLTATSMFCTLCGKDYASQDALRRHITEEHQPPIMNTLPQTPATTSTTTNSNATSQSTSERKVTSMTPTSSYCEICNKELCNKYFMKTHMQRMHGIEIENGAQIGGVICNICNKELCSKYFLRVHKHNTHGIVDENAPSSVKQEALEATNTDDALKPEQLGDLSHRYFTHFTEVCPICSRRFRSIKWLKAHLMGEHGKAGIDKWREMEQHYQTASRTTNRTTSTPKNTQQGSNLKIPNGFEITQQHKSADYTGLGNQVLSNLLGSSSEDQQLKSYRCSYCTFTTTVLPFLFLHERSHVHSRENAEGEKSLQCPICSQSFHQPELLHQHLLAAHQFPTLLSHFPPPMLNNLTPDAEKLNEVKERLELETKEDRIGNSPQVTANKSVPEPIRNQRQDDTTVQVTPQGVYKCAQCCYATTNLNRIKKHVRKDHRTIGDPTDSVIAELGRTLKDVANRHKVPACYAMPQDMNSNPDKTIMQPFLIEEQDAMQAGEESGSDKRFAPALVYLPVKSRINNPLTASFTLSPA
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -