Basic Information

Insect: Megachile rotundata
Gene Symbol: -
Assembly: GCA_000220905.1
Location: NW:2307812-2316157[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 21 1.1 67 3.4 3.9 2 23 312 334 311 334 0.96

2 21 0.0091 0.56 10.0 4.8 1 23 384 406 384 406 0.98

3 21 0.076 4.7 7.1 0.9 1 23 455 477 455 477 0.97

4 21 0.064 4 7.3 2.2 1 22 532 553 532 556 0.90

5 21 1.6 97 2.9 3.2 1 23 565 588 565 588 0.83

6 21 0.00031 0.019 14.6 1.3 1 23 593 615 593 615 0.97

7 21 0.0006 0.037 13.7 0.3 1 23 663 685 663 685 0.97

8 21 0.00052 0.032 13.9 0.1 1 23 691 713 691 713 0.97

9 21 7.9e-06 0.00049 19.6 1.6 2 23 758 780 757 780 0.96

10 21 1.1 67 3.5 4.9 3 23 789 810 787 810 0.87

11 21 0.00053 0.033 13.9 2.7 1 23 817 840 817 840 0.91

12 21 0.0004 0.025 14.3 0.0 3 23 852 872 850 872 0.92

13 21 0.034 2.1 8.2 0.2 1 20 934 953 934 953 0.97

14 21 0.039 2.4 8.0 0.3 2 23 973 994 972 994 0.96

15 21 2.5e-05 0.0016 18.0 0.7 1 23 1008 1030 1008 1030 0.97

16 21 0.0001 0.0063 16.1 5.9 1 23 1053 1076 1053 1076 0.96

17 21 0.025 1.6 8.6 3.4 2 23 1131 1153 1130 1153 0.93

18 21 0.0028 0.17 11.6 0.6 2 23 1181 1203 1180 1203 0.94

19 21 0.085 5.2 6.9 1.0 1 23 1210 1234 1210 1234 0.95

20 21 0.0065 0.4 10.4 1.6 1 23 1239 1262 1239 1262 0.98

21 21 0.083 5.1 7.0 3.0 2 23 1292 1314 1292 1314 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	21	1.1	67	3.4	3.9	2	23	312	334	311	334	0.96
2	21	0.0091	0.56	10.0	4.8	1	23	384	406	384	406	0.98
3	21	0.076	4.7	7.1	0.9	1	23	455	477	455	477	0.97
4	21	0.064	4	7.3	2.2	1	22	532	553	532	556	0.90
5	21	1.6	97	2.9	3.2	1	23	565	588	565	588	0.83
6	21	0.00031	0.019	14.6	1.3	1	23	593	615	593	615	0.97
7	21	0.0006	0.037	13.7	0.3	1	23	663	685	663	685	0.97
8	21	0.00052	0.032	13.9	0.1	1	23	691	713	691	713	0.97
9	21	7.9e-06	0.00049	19.6	1.6	2	23	758	780	757	780	0.96
10	21	1.1	67	3.5	4.9	3	23	789	810	787	810	0.87
11	21	0.00053	0.033	13.9	2.7	1	23	817	840	817	840	0.91
12	21	0.0004	0.025	14.3	0.0	3	23	852	872	850	872	0.92
13	21	0.034	2.1	8.2	0.2	1	20	934	953	934	953	0.97
14	21	0.039	2.4	8.0	0.3	2	23	973	994	972	994	0.96
15	21	2.5e-05	0.0016	18.0	0.7	1	23	1008	1030	1008	1030	0.97
16	21	0.0001	0.0063	16.1	5.9	1	23	1053	1076	1053	1076	0.96
17	21	0.025	1.6	8.6	3.4	2	23	1131	1153	1130	1153	0.93
18	21	0.0028	0.17	11.6	0.6	2	23	1181	1203	1180	1203	0.94
19	21	0.085	5.2	6.9	1.0	1	23	1210	1234	1210	1234	0.95
20	21	0.0065	0.4	10.4	1.6	1	23	1239	1262	1239	1262	0.98
21	21	0.083	5.1	7.0	3.0	2	23	1292	1314	1292	1314	0.92

Sequence Information

Coding Sequence: ATGGACGAAGTGGacgaattacaaaatatggAAAGTGTGTGTAGGCTTTGCCTTTCTACCGACGAACCAAAATTGTCGGTATTTGGGGAACAAGAATCCCCGGTATCATTAGCCAATAAAATACAAGCCTGCTTGTCAATTGAGATTTTAGCCACGGACAGGTTGTCAACACAAATATGTGCAGAATGCGTTAAAAATGTGAACCAATGGCATAATTATAAAGAAGCGTGTCTTCGCTCCCAGGATAAATTACGTTCATGGTTGGAAAAACATGTACAAACAGGTCCACTGgtTGTAAGTATTAAGAGTGAACCTATAGATCTGGAATTTTATGAAGATAACATTGAAGTGATCTCTGAATCCACAAATGAGTCAGATTTGGAGCCAACTAATATTGAAGACACCCCAAACAATTTGGTAAATAATGTTCATGTTCAGGAACTAACTgataatgaaatagaaatagatAGAGATCGATCAGCATTAACTGATAATGAAACGTATTCAGAGAAAGATCAATCAGTCTTAACTGacaatgaaatatatacaGAGAGAGATCAACCAGTGCTCACTAATAATATAACAGATGTAGAGAGAGATCAGTCATCACTAACTGATAGTGAGATAGATGTAGACAGAGATCAACCATTGTTGACTGATAATGAAATAGATATAGAAGGAGATCAACCAACACTCTCAAAGGAAatagatatatctataaaGTTAGAACCACAAGAGGACTATGATACAGATTGTACTATAGAGATAGAATCTGTTACAGGTGGTGAACTACAGAATCAGCTTCCAAATAAGGAAGATACGGTTATGGAAGCTGATTCTACACAAAAGTTTAATGCATCTGCAACAGTAAACAAGAAAAGAACTAGACGGGGTCCGCACACCCACTTTAGAGGAACAAAAGTTTTTAAACAGAAATGTgtacattgtcaaattattttgcattctAAACAGTCTTACGCGAAGCACATGGAAAGATTTCATACCGCCAAACAGAATGGTACTGCCGAGCTGACAGAATTACAGGATGGCGAAGAATTGGTCGAAGATTTGGAAGATGAATTGATGAGCATGGAGAAGGATGCTCCCTTGACTCAAGTACAACAGAACATTATCAGtcaattaaaaacttattCGTGTTACACGTGTCAGCAACATTTCAGCGATCGCAGGAACACGCTTAATCACATTCGTCAACACATGCCCGATTTAAGACCGTACACGTGCATCGCATGTATGACAGAGTTTCCAGATCGATCGATGTTCAAGCTTCACTGCGAAGTGTCGTTTGAATGTGCAATGAAAATTGCTTTGGTTATACCAAAACAGGGCGAGGAAAAGTACTTCACGTGTAATATGTGTTTGCGCGCCATGCGAAACAGAAGGGAATTACTTAGCCATCTGTCGCAGCACTCCGACAAGCAGTATGAGGAGTTGATATCACCTTCACGATCTCCTCCTAAATTGAAACCAATGGCGCCTTTGCCACCGCCTAAACCAAAACAAACGAATAAAGTGCACGAAGGAGGTCTGCAGATTCCTCAGCCTTACAATAATGGCGATTCTCTGTACAATCACCCATGTGACTTATGCGGAATGATCTATAAGTTTAGACCTAACATGTTGAGGCACAGAAACTTGTGTTTACATTTGCCACCAGAGAGCAGGACATCCTATAGATGTGTTCACTGTGGACTGACGTTTCTTGtgtttaaaaagtttcacAGTCACATTGTTATGGAccataaaaagaaagattttGTTTGTTCCGTTTGCAACGCCAAATTTAGATCTCCAAGTGACTACCTGACACATCACGAATCGCATCGTGGTACTCGTAATAAAAAGCCGTCGATTGAAAACAATCACGAATCAATGACGACCATGCCAAACATATCAACGCCTATCAAAGACTGGGACACTTTTGAGGCTGAAATAAACGCGAACAAAATAACCAATAGCAATAAGTACAGTTGTGCTCTTTGTAACTTGGAATTTGCTACCAGAACCGAACTAACAGAGCACAGGAATCTTCACCTGAAAGTGAAGATTTATTCGTGCGTTATTTGTCGCAGCATGTTCAGCAGTGCTGGTGCTTTGGAGATCCACATGAAGGATCACGGTATAGAAGATCCAGGCGAGAGGGACGCAAACATCTCGTGTGTGGAATACGGAACGACTAAGAACGAGGTGGAAGACACAAAGCCATTAAATATGACCGCCGTTTCGGATCCTGGGGCGACCAAAAATAGTAAATGCACCATGTGCAGTAAACAATTCTCGAACTACGCAAATCTCAGACGACATGTAAGAAACGTGCACAAAACAGGCAAACCGTACGTACATTGTCCCGAATGTACTCGGGTGTTCAGAAGTACCGAATCGTGCCATCGTCATGTGACGTTGCAGCACAAATCCTCAAGGACGTTATACCAGTGTCCTCAATGTCCAAAGACCTTTGTTTTCAAAACAAACATGAATCTTCACTGTCGGAATGCGCATAACAATGGGCGTAACTCGTCCGGTGATTGGGCTTGTGATATCTGCGGCAAGACATTCTACGAAGAAGCGTCTCTGAAGATACACAGGGGCTGGCACAACCGAACTAACTATCGGTTGATTGCCGATATCGCACAGGAAGGAGGGGATCAGAAACGGGTGAAACAGTTCAAACACCCGTCGTCCAAAACTCAAGATCAATCGCCCACAGCGAACACGAGTCGGCCGGCTAGGGCGAGAAAGTCCTTTCCCAGTCCGGCACCGTCGAAGGGTAGCGGTAATTTCCAATGCCAAGTTTGTAACGATAAATTCAACGACGTGGTGGAGCTACGGAAACACTTGTGGGATGTTCATTGTGCCCGCAACAAGTCCGAGAAGAATTTCACCGACGTCAAACTGCAGTGCGACCTTTGCACACATATCTTACCTAGCCAGGAGGCGTTCAACATGCACATGCAGTGGCACAAAATTCACCCCATTTTGACCGAGGTCAACAAGTCTGCCTTCCCCTGCGACATCTGCGGCAAAAACTACAGTTCCAAGAAGGTATTGTGGAGACACAAGAAGCTGCATAAAGCCACGGTGGCAGCCGCTTCCAAGTTCCAGTCCATGTCCAGAAAGCCTACCGTGTCCAGTCAGTACACGTGTCACGCCTGTCACAAGTCATTCAGCAGTAATCAGTCGCTACAGCGTCACAAGATGAATTTGCACATGGACATGTTCAGCGAACGAGCGCCAACGTTGTTCAACAACACGGCAAAAATGTCGCCGGTGGAACCAAAACCGAAGAAAGTGAAATTGGAAGCGGAAGACGTGACGCAGAAGTCAACGACTGTCCTGAACACAATGCGCGCCGGCGGCAAGAAGGCTGTAATGTGTCATGTTTGCAAAAAATTCTTCCCCAACATGAGCGTACTCTACAAGCACAAACAGCACGCTCATACCAAGGCCCGCACGGTGAAGAACGTCGCCAAGAGCCCGACCATGGAGTTAATTCCGTTGGCCGGTCCCGAGGGCAGGATGTCTTGCAACATTTGTTTCAAAGAGTTCCCTGGTGTGTCGAATTTGCGGCAGCACTTCAGCATGAAACATAAGAACAACACGCTCAAGTACATCTGCTCTTTCGAGGGTTGCAAGCTGATGTTCCACACGACGGTAGCACTGAAGAATCACGAGCTATCGCACACCTCTATGATCTACAGTTGCAATCTGTGCGATCGGCACGTGTTTACCAAGCAAGCTATGTCCAGTCACATGCTGACCGTGCACAAGACTATCTACCACGCTGAAGAGAACAAAAACTTCCACAGGGAGACAGACCTGAGCACCTACGTGGTAGAAGGTGCAACGGACGCAACTTGTCCTCATTGCAAGATCAAATATCCCAACAAGAAAGCCATGAAGATTCACTTCTTCAAGTTCCACGATAGCGCGGATCGCTAG
Protein Sequence: MDEVDELQNMESVCRLCLSTDEPKLSVFGEQESPVSLANKIQACLSIEILATDRLSTQICAECVKNVNQWHNYKEACLRSQDKLRSWLEKHVQTGPLVVSIKSEPIDLEFYEDNIEVISESTNESDLEPTNIEDTPNNLVNNVHVQELTDNEIEIDRDRSALTDNETYSEKDQSVLTDNEIYTERDQPVLTNNITDVERDQSSLTDSEIDVDRDQPLLTDNEIDIEGDQPTLSKEIDISIKLEPQEDYDTDCTIEIESVTGGELQNQLPNKEDTVMEADSTQKFNASATVNKKRTRRGPHTHFRGTKVFKQKCVHCQIILHSKQSYAKHMERFHTAKQNGTAELTELQDGEELVEDLEDELMSMEKDAPLTQVQQNIISQLKTYSCYTCQQHFSDRRNTLNHIRQHMPDLRPYTCIACMTEFPDRSMFKLHCEVSFECAMKIALVIPKQGEEKYFTCNMCLRAMRNRRELLSHLSQHSDKQYEELISPSRSPPKLKPMAPLPPPKPKQTNKVHEGGLQIPQPYNNGDSLYNHPCDLCGMIYKFRPNMLRHRNLCLHLPPESRTSYRCVHCGLTFLVFKKFHSHIVMDHKKKDFVCSVCNAKFRSPSDYLTHHESHRGTRNKKPSIENNHESMTTMPNISTPIKDWDTFEAEINANKITNSNKYSCALCNLEFATRTELTEHRNLHLKVKIYSCVICRSMFSSAGALEIHMKDHGIEDPGERDANISCVEYGTTKNEVEDTKPLNMTAVSDPGATKNSKCTMCSKQFSNYANLRRHVRNVHKTGKPYVHCPECTRVFRSTESCHRHVTLQHKSSRTLYQCPQCPKTFVFKTNMNLHCRNAHNNGRNSSGDWACDICGKTFYEEASLKIHRGWHNRTNYRLIADIAQEGGDQKRVKQFKHPSSKTQDQSPTANTSRPARARKSFPSPAPSKGSGNFQCQVCNDKFNDVVELRKHLWDVHCARNKSEKNFTDVKLQCDLCTHILPSQEAFNMHMQWHKIHPILTEVNKSAFPCDICGKNYSSKKVLWRHKKLHKATVAAASKFQSMSRKPTVSSQYTCHACHKSFSSNQSLQRHKMNLHMDMFSERAPTLFNNTAKMSPVEPKPKKVKLEAEDVTQKSTTVLNTMRAGGKKAVMCHVCKKFFPNMSVLYKHKQHAHTKARTVKNVAKSPTMELIPLAGPEGRMSCNICFKEFPGVSNLRQHFSMKHKNNTLKYICSFEGCKLMFHTTVALKNHELSHTSMIYSCNLCDRHVFTKQAMSSHMLTVHKTIYHAEENKNFHRETDLSTYVVEGATDATCPHCKIKYPNKKAMKIHFFKFHDSADR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00962002;
90% Identity: iTF_00963365;
80% Identity: -