Mrot006345.1
Basic Information
- Insect
- Megachile rotundata
- Gene Symbol
- -
- Assembly
- GCA_000220905.1
- Location
- NW:725693-768885[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 22 0.00012 0.0075 15.9 1.4 1 23 369 392 369 392 0.96 2 22 3.8e-05 0.0024 17.4 5.2 1 23 398 420 398 420 0.98 3 22 0.014 0.84 9.4 7.6 1 23 429 452 429 452 0.94 4 22 0.003 0.19 11.5 1.2 1 23 458 480 458 480 0.91 5 22 2.5e-05 0.0015 18.0 2.4 1 23 485 508 485 508 0.96 6 22 0.0013 0.081 12.6 0.9 1 23 514 536 514 536 0.98 7 22 5.5e-07 3.4e-05 23.2 0.8 1 23 540 562 540 562 0.98 8 22 0.00081 0.05 13.3 7.4 1 23 568 590 568 590 0.99 9 22 5.9e-05 0.0036 16.9 3.2 1 23 596 618 596 618 0.97 10 22 3.8e-05 0.0023 17.5 1.4 1 23 730 752 730 752 0.97 11 22 3.3 2e+02 1.9 6.7 1 23 788 811 788 811 0.94 12 22 0.011 0.66 9.8 0.9 3 23 816 836 814 836 0.92 13 22 0.053 3.3 7.6 0.4 1 23 844 867 844 867 0.90 14 22 0.11 6.9 6.6 7.6 3 23 931 951 930 951 0.97 15 22 0.013 0.78 9.5 4.1 1 23 959 982 959 982 0.97 16 22 0.052 3.2 7.6 1.3 1 23 997 1020 997 1020 0.95 17 22 5.9e-07 3.7e-05 23.1 0.8 1 23 1026 1049 1026 1049 0.96 18 22 0.00029 0.018 14.7 0.8 2 23 1055 1077 1054 1077 0.94 19 22 0.0015 0.095 12.4 1.6 1 23 1082 1105 1082 1105 0.97 20 22 3.8e-08 2.3e-06 26.9 0.6 2 23 1112 1133 1111 1133 0.97 21 22 1.6e-05 0.00096 18.7 0.8 1 23 1139 1161 1139 1161 0.98 22 22 6.1e-07 3.7e-05 23.1 0.1 1 23 1167 1189 1167 1189 0.98
Sequence Information
- Coding Sequence
- ATGTCCTCCCTCGATTATCTGGACTTGTGTCGGCTGTGTCTCGTGAAGGACCGTGTTTCGGTGCCGATTTTCGAGGGTGAAGGAGACGTACGGcaaatatttctcaaaatcgCCGCCTGTCTACCGGTCAAGGTTGCAAGAGAAGACAAGTTACCCAAAAAGATATGTGATGATTGCGTGTATAAAGTAgagctattttatgaattttggaatacaaCAGCGAATGCAGAAAAGCAGCTTCTACAATGGCTAGGAGGAGTCAATTTAGAAGACAAACAGGGTTATGTTACCAATACTCTCAATCAgaatgtaaTGAAACAAGAACAGAGTTCAGAGAACAGGTTAGATGGCAATGTGATGCAGCAAGTTGGCGAGCATCAAAACAATATGGGTATGGGTATGATGGATAATATGGGCCTGGGTATCCCTATGATGATATCCAGTGCTAATCAGCAGCAACAAATAACCTCAGTTCCTATGGACACAAGCGGTAATTCTGTACAACCCGTTCAGGCATTGCCTGGTCCAAGTTCACAAACCACACATAACCAAATATCACAGAATCAATCGAGCTCTGCGCAAcaagaagatgaagaagaaagTAGCGAAGATGAAGAGAACTCGGATGATGAATGTGATGGAGATGAAGgCCTACctgtaaaagaagaaagtgaGGAAGATCCCAATAATAGAACTATAGAGCCTACAACTTTTGTAAATGTTTCCTTGGCATGCGACGAAGCTGGTCCTTCTGGGCTACAACAGAAAATCTCAGATATACCTGAGATGCCAATGCCGCAGTCAACAGACGGGGATCCCAAAACTGGGAGATCGCCGCAGCTCATAAATCAGAAGCTCGGTAGCCAAGAAGATTCAAAAGCACGCAAACCAGCCTTCCTCCAGAGAAGAAGACTCTTACGAGTTTCGAAAATCCGCAGACGCAAAAGTAACAGACACTACGAAACAAAAGAAGGAAGTGTTCAGCGGGAAGAAAAGAAGTCTTCGATCCGTTCAACCAGCAAGAAACTACCTAACGATTGTTCAGCTAAATTACAGAGCAATCCTCAGCAGGAAGATCTCTATAAAAAGCTTCACGACGGCACGTACACCTGCGACATTTGTCAAACAACATTCGAACAGAAGAGCAAGATCCTCCGTCACATCACCAGCAAGCACAGTTTCCATCGGCCGTTTAAGTGCCAGACCTGCGACAAGACGTTCAAGTACAAATGCGACCTGAAGGCCCACAAGCTGGTCCACCAGGAGGTCGACTCGAGTTTGCTGCACTGCTGCGACAAATGCGACTATCGAACGAAAACGAAGAACAACCTGAAGTCGCACTACATCAGAAGACACACGGACGACTACAAGTTCGCCTGCGAGCACTGCGGCAAGCGTTTCAAGATGGAGTGGGACTTGAAGTTCCACGTTGGCACTCACAGCAACTCCCAGCACATGTGCGACGTTTGCGGAAAATTTTATACTAGCAATTACTCGCTGTACAAGCATAGGAAGGTGGCCCACTTGAACGAGTACAAGTTTCAATGCAGCGTTTGCAATAAGAGGCTACTCACGCAGGAGAACCTGGACAACCACATGCAGCAGCACAGCAGAACGTACGAGTGCAAGGATTGCGGCAAGGTGTTCGCCTCGAAGAGGTACCTGGCGACACACACGACTACACACACTGGGGTCAAACCGTATACTTGTCATATTTGTAAGAAGAACTTCAGAACGTCGCATATGAGAAACACGCATCTGCTGACGCACTCGGCGGAGAGGCCACATATCTGTGATCTTTGTGGACAATCTTTTAAGAGGAGGTATTATATGATAGAGCATCGGAGGAAGCATCCTGATGCTCACCTGTCGTCGCCACCGGTGCCTCTGGGGAAGAAGAGGAACGTTGCTGAATTGGATGGACAGATTGTGACTGAATTTCGGGCGGAGATTTCTTTgGATCCTGTCAGCTGCAAGAAGATGACCATCGGAACTTCCGGTCAACTTACAGAACACTCCGTCCCGACGCAGCAGGTCCACACAGTGAAACTCGAAGAGAGCTCCGAAACGACTATTTTCTTAAAGATGGAGGAAGTGCCACATAAAGACGTTCAGAAAACGAATTGCGAGACGAATTCTTACGTTTCGGGTTCTCTGATACACCTCTGCGAAGTGAGCATCGATTACTACACGTGCAACAAGTGTGGGATCAAGTTCCCTACCGAGAGCATGCTGAGCAAACACAAAATGTTCCACAAACTGCACTCGTGGATTCGCAAGAAACGTCTGCGTGCGAAGAATCAGCTAAAATCGGGAAAACTAATCAAACAGAAGTCTCTGAAAAACCCAGAAAAGATGAAGTACGTCTGCATGTGCTGCAGCTTCAGCTGCAACAGGAAGTCCACCATCACCATCCACATGAAGAAGAAACATTTAGAGATCTCGTGCATAATCTGCGACTTGAAATGCAACGATTACTCCACGTTGGCGAAGCACATGGAGAAACACAGGAACGCGAAGACGAAGTACTTCAAGTGCAACGTGTGTAGCTTTGTCAGCAAGAAGAGGGGTGCTTTGGTGTCCCACGTGGTTCAGACGCACCGGAAGACTGatgagaagaagaagaggacgCAGATGAAGCGTGACGTCAAAGTTGAGGTGAAGAAAAGCCCAGAAGAAGCAAAGGATCCTCTAGTTGACTCGTGCACATCGTCAGAGTTCGACTGCAAGGACGAGGTGATATCAGAACCAGAGGACGACAAGAACTTCGACAAGGATCCTGTGGAACACTGTGACTTGTGCGACTTCACGTGTTCGAAAAGGAGCACCCTGTACTCGCATAAACGCAGACACAAGGTGGACGTAGCTGAGGTGTATTTCTGCAACGAGTGTCCGTTCAAGACCAACAAGAAGTCGTCCCTGTATTCGCACAGGAAGAGGAAGCACAGACCACCTAAACCTCTCACGGAAGATGGCCAGCCACAGTTGTTCTACTGCGCCCAGTGCGACTACAAGAACAAGAACAAATACGAGCTGAGAGTGCATGTAGCCAGGAAACACACCAACGACTTCAAGTTCTCCTGCGAGATTTGCGGCAAGAAGTTCAAGGTGAAAGGCGACCTGACCAACCACATACGTTTCAGCCACAAGGAACAGCCCGTCATGTGCGACGTCTGCGGTAAAACCTGTCCAAACAGTAATTCGTTGTACGTGCATCAGAAGTTCGCTCATTACAAGGCCCAGTACGAGTGCCATTTGTGCAAGAGGCGAATGGTCACCCAGGAGAACCTGAACGAGCATCTGATCAAGCAGCACGAGAACAGGAAGGCCGTGATGTGCGAGGAGTGCGGGAAGACCTTCTCCAGGAACAGCAGGCTGAAGGTGCACATGAGAGTCCACACCGGAGATAAACCGTACAATTGCACGATCTGCAGCAAGTCGTTCGCTCGGAGGACGGCCATGAAGCAGCATCTGCTGATACACACCGGGGTTAGGCCGTACGTCTGCGACATATGCGGGAAGGCGTTCACACAGAAACCTGGCTTGATCAGCCACAGGAAGTCGCATCCTGGATCGCATCCGCCGCTTCCGAGAATCTTCATTGATCACATACTGCAGGACGTTATGAACAAATGA
- Protein Sequence
- MSSLDYLDLCRLCLVKDRVSVPIFEGEGDVRQIFLKIAACLPVKVAREDKLPKKICDDCVYKVELFYEFWNTTANAEKQLLQWLGGVNLEDKQGYVTNTLNQNVMKQEQSSENRLDGNVMQQVGEHQNNMGMGMMDNMGLGIPMMISSANQQQQITSVPMDTSGNSVQPVQALPGPSSQTTHNQISQNQSSSAQQEDEEESSEDEENSDDECDGDEGLPVKEESEEDPNNRTIEPTTFVNVSLACDEAGPSGLQQKISDIPEMPMPQSTDGDPKTGRSPQLINQKLGSQEDSKARKPAFLQRRRLLRVSKIRRRKSNRHYETKEGSVQREEKKSSIRSTSKKLPNDCSAKLQSNPQQEDLYKKLHDGTYTCDICQTTFEQKSKILRHITSKHSFHRPFKCQTCDKTFKYKCDLKAHKLVHQEVDSSLLHCCDKCDYRTKTKNNLKSHYIRRHTDDYKFACEHCGKRFKMEWDLKFHVGTHSNSQHMCDVCGKFYTSNYSLYKHRKVAHLNEYKFQCSVCNKRLLTQENLDNHMQQHSRTYECKDCGKVFASKRYLATHTTTHTGVKPYTCHICKKNFRTSHMRNTHLLTHSAERPHICDLCGQSFKRRYYMIEHRRKHPDAHLSSPPVPLGKKRNVAELDGQIVTEFRAEISLDPVSCKKMTIGTSGQLTEHSVPTQQVHTVKLEESSETTIFLKMEEVPHKDVQKTNCETNSYVSGSLIHLCEVSIDYYTCNKCGIKFPTESMLSKHKMFHKLHSWIRKKRLRAKNQLKSGKLIKQKSLKNPEKMKYVCMCCSFSCNRKSTITIHMKKKHLEISCIICDLKCNDYSTLAKHMEKHRNAKTKYFKCNVCSFVSKKRGALVSHVVQTHRKTDEKKKRTQMKRDVKVEVKKSPEEAKDPLVDSCTSSEFDCKDEVISEPEDDKNFDKDPVEHCDLCDFTCSKRSTLYSHKRRHKVDVAEVYFCNECPFKTNKKSSLYSHRKRKHRPPKPLTEDGQPQLFYCAQCDYKNKNKYELRVHVARKHTNDFKFSCEICGKKFKVKGDLTNHIRFSHKEQPVMCDVCGKTCPNSNSLYVHQKFAHYKAQYECHLCKRRMVTQENLNEHLIKQHENRKAVMCEECGKTFSRNSRLKVHMRVHTGDKPYNCTICSKSFARRTAMKQHLLIHTGVRPYVCDICGKAFTQKPGLISHRKSHPGSHPPLPRIFIDHILQDVMNK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -