Basic Information

Gene Symbol
-
Assembly
GCA_945859565.1
Location
CAMAOB010000037.1:938036-939741[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.00015 0.015 16.0 0.2 1 23 115 138 115 138 0.94
2 10 0.0017 0.18 12.7 1.0 1 23 144 167 144 167 0.95
3 10 6.5e-05 0.0067 17.2 2.2 1 23 183 206 183 206 0.97
4 10 0.041 4.2 8.3 4.2 1 23 227 250 227 250 0.97
5 10 2.1e-05 0.0021 18.7 1.3 1 23 256 279 256 279 0.95
6 10 1.6e-05 0.0016 19.1 0.5 2 23 285 307 284 307 0.95
7 10 0.003 0.31 11.9 0.1 1 23 312 335 312 335 0.95
8 10 2e-07 2e-05 25.1 2.2 1 23 341 363 341 363 0.98
9 10 1e-06 0.00011 22.8 0.8 1 23 369 391 369 391 0.97
10 10 3.3e-05 0.0034 18.1 1.4 1 23 397 419 397 419 0.97

Sequence Information

Coding Sequence
ATGTTCTCTCAAGATAAGCCACAAATTGTTGAACTGTTCTGTTTGACTCTAAACGGGAACGGACGTTTCCTGTACGGCAAGGAATCGATCGCGATGCAACCGTGGCAGGTTGTCGACGTGGAAGGTAGCCTCTACTATGCCTTCCTTCCAGCGAACCAAGTGGAAACGGAGTTCACCAAACTGTCCGACAAATCTCCGGAAGCGCAACACAGGAACAGCGCCGAAGAGAAGACGTACATCGTCGACGAAGAAAAATCGCCCGTCGACGACGCGTGCACGGTGAAGATAAAGAAAGAGAACGCCGAAGACGCGTCCACAGATAAACACGAAGACGGCACCGTGTACGCCTGCAAGGAGTGCAACATCTCGTTCCCAGTCCTGCAGATGCTTAAACGTCACAGAAACGCGGTGCACGAACAGGCACAGCGTTACAAATGCAAGGTCTGCCTGAAGGTCTGTCGCAGTCTGGTGGCCTTCAAGATGCACATCGCGTTGGAGCACAAGGAGGAGGAGGAGCAGAGCCTGAAGGACGCGGAGAGCCTCACGTACACCTGCAATTTCTGCGACTACGAGAGCACCAATAAATCCACCCTGACCTCGCACATCAGCAGAAAGCACACGGGGAAAACTATAGACAGACGAAGAAGCAGTTATGGCTCCAGcacggaaccgaaagagtactcctgcgacgagtgcgagttcaagtgccagaaccgaaggaagttgaaggaacacctggagcgtaagcatgcgtccgattacaagtacgactgcgagtactgcggtaaaaagttcaaggtcaaaggtgacatgaggctacacgtgcggttcaagcacaaagagggacccatcgtgtgcgacgtttgtgggaaaacttgctccaatagcaattctttgtatgtacatcagaagtgggcacatttcaagcccaaatacgagtgcgccatctgcaagagacgaatggtcacccaggagaacctggatcagcatatccttttgcaacacgagcgcagagagagcttcgtgtgcgaggaatgtggaaagtccttttcggagaatcatcgtctgaagcaacatatgatgacacataccggagacagaccttacgactgccatatttgtggcaaagcgttcgctaggagaactgcttataggcaacatttgttgatacacacagggaagcgtccgtatatctgtgatatctgtggaaaaacattcacacagaaaccgggactcatctgccacagaaagtcgcaccctggggtgcacccaccgctacccgttgtgcacatcgatcacattcttagtgatttcatgaagaaggaATGA
Protein Sequence
MFSQDKPQIVELFCLTLNGNGRFLYGKESIAMQPWQVVDVEGSLYYAFLPANQVETEFTKLSDKSPEAQHRNSAEEKTYIVDEEKSPVDDACTVKIKKENAEDASTDKHEDGTVYACKECNISFPVLQMLKRHRNAVHEQAQRYKCKVCLKVCRSLVAFKMHIALEHKEEEEQSLKDAESLTYTCNFCDYESTNKSTLTSHISRKHTGKTIDRRRSSYGSSTEPKEYSCDECEFKCQNRRKLKEHLERKHASDYKYDCEYCGKKFKVKGDMRLHVRFKHKEGPIVCDVCGKTCSNSNSLYVHQKWAHFKPKYECAICKRRMVTQENLDQHILLQHERRESFVCEECGKSFSENHRLKQHMMTHTGDRPYDCHICGKAFARRTAYRQHLLIHTGKRPYICDICGKTFTQKPGLICHRKSHPGVHPPLPVVHIDHILSDFMKKE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00684939;
90% Identity
iTF_00963997;
80% Identity
-