Basic Information

Gene Symbol
-
Assembly
GCA_945859565.1
Location
CAMAOB010000027.1:4228380-4230492[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 0.015 1.5 9.7 0.9 2 23 126 147 125 147 0.93
2 11 0.00032 0.033 15.0 2.8 2 23 222 243 221 243 0.94
3 11 6.1e-05 0.0063 17.2 2.6 1 23 385 407 385 407 0.98
4 11 3.9e-07 4e-05 24.2 0.9 1 23 413 435 413 435 0.98
5 11 3.3e-06 0.00034 21.2 1.7 1 23 441 463 441 463 0.97
6 11 2.2e-05 0.0023 18.6 1.5 1 23 478 500 478 500 0.97
7 11 1.5e-08 1.5e-06 28.6 1.1 2 23 507 528 506 528 0.98
8 11 2e-07 2.1e-05 25.0 3.2 1 23 534 556 534 556 0.98
9 11 1.7e-06 0.00017 22.2 5.7 1 23 562 584 562 584 0.98
10 11 1.4e-05 0.0014 19.3 4.3 1 23 590 612 590 612 0.96
11 11 3.9e-05 0.004 17.9 3.0 1 23 618 640 618 640 0.99

Sequence Information

Coding Sequence
ATGTTCATCGTTACGAAAGAAATCGATGGTGACAATATCGGCAAATTATGCCGTACATGTTTAAGAGAAGACGGTGACAAAATGGTTTGTTTATTCGTGGGACCGGCTGGCTCTTCTCTTGCTGCAAAATTGCGGTCTCTCTCGTGTTTGGAAGTTTGGCAAGGTGATGGTCTTCCAGAGAAAATGTGTGATCGTTGTGTAACCAGAGCAGAGTCAGCTTTGCTGTACAGAGAACAATGTCGAGCTGCGGACAGGGCATTGAGACAAGCTCTTTTGAAGGTTTCTAGTTTAACTTCCTATACTACAGTATCCGGATGCAAGTTGTATCAACAGAACCAAGGTTTCCTACCAGTAGAAAATCCTCGTAAAACCTTGAAATGCATAGAATGTGGGGCTGCATTTACCAGTTATCAGGAACTCTGTACTCATAACAGGCTGCATCTACCTTTCGTTCAAGACAACGTACCAACAAGACATATGCACATTGTCGAATCTCAGAATCCTTACTTTAATTTTAACTTTAATTTCAATTTCAATCATTCGAACAACAACCTGACAGGCGATGACGTTCAGCATGCGCAATCATCCACACTGATTAGGCCAAATACGATGCAAACGATTCCACCGATCGGTGAAAATCCAAGTCGTGCTGCTTGTGCTCTACATTGTTCCTTGTGCAATCGTACCTTTACCAATAGAACGCAATTGATTAATCATAATATTTCACACAACGCGGACAACATAGATATTCCTTGTGAAAACGAGAGTATAGATATCTGCGAGAATTCTAATCAGGTTCCACAAAATTTGAGTTACGAAAGATCTATTAATTCCGTCGGAAATTCCATCCAAAACTTATCTTATCAAAGATCGGCGACGAACGATAACAACGAGATGCAGAATTTATCTTTTTCCGAGAACATCGATCTTGTGGAGGACGTTCGAGATGGCAGCCCTCCAGAGCGCGTGCAAAATACGTCGTTACACGACTCTAATGCCTACGTATCCGATTCGCGTTCGATCGTTCGTTTCTCGAAAAACGGTGAACGCGCGAATAACGGGAAGAACATCGACGAGTATCGATCGTGTACGAACGTCGTTTACGAAGGAAGCGTAGAAAAAGAAAATTTGACGAACGTACAGCGTAAAAAGTTCAAGTGCGAACTATGTTCTAAACTATTCTCTCAGAAATCAAAATTGCTGACGCATCGACTGTCGCACTCTAGTCAACGACCGTTCAAATGTTCCGATTGCGAGAAGGCTTATTCGACCAAGAGCAAATTAAACGCGCATGTACGATTGCACACGAAAACGAACGTGCATTCGTGTAAACTATGCGACAAAGTGTTCGCGTATCCCTCCTACTTACGCGAACACGAGAAAACCCACGATCAAGATAACGGTATCACGAACAACGAGGGGGGCCaatctttcgagtgctccgcttgcaaaaagaggtttcgatccttgaaaaatttaagagctcacgaacgacttcatacggggaaaggtttggtacagtgcgaaatatgcgataagagatttagtcaacgttacaatctaaaaattcatttgcgtacacataaagcgacgaggccgcacaagtgcgaatattgcgacaagtgtttcgtacaaaagggtaatctagcggaacatttgaggattcatacgaaagtcaaaccgttcgaatgtaaattatgtaaaaagcgtttttctcaatcgagtcacttgaaaaatcaTCAATCATCGCATACCACTGTCAGACAACATCAGTGTCGATTATGCGGCAAACGGTTCAAATTGGCAAGCCACCTGAAGAGACATTTAATTTTACACGACGGTACCAAAGCGTACAGATGTAATCGGTGTAATCAGTTGTTCTCGCAAGCGTTTAGCCTAACGAGGCACTTGAAAAGGCACGAATCGCAAACGTAA
Protein Sequence
MFIVTKEIDGDNIGKLCRTCLREDGDKMVCLFVGPAGSSLAAKLRSLSCLEVWQGDGLPEKMCDRCVTRAESALLYREQCRAADRALRQALLKVSSLTSYTTVSGCKLYQQNQGFLPVENPRKTLKCIECGAAFTSYQELCTHNRLHLPFVQDNVPTRHMHIVESQNPYFNFNFNFNFNHSNNNLTGDDVQHAQSSTLIRPNTMQTIPPIGENPSRAACALHCSLCNRTFTNRTQLINHNISHNADNIDIPCENESIDICENSNQVPQNLSYERSINSVGNSIQNLSYQRSATNDNNEMQNLSFSENIDLVEDVRDGSPPERVQNTSLHDSNAYVSDSRSIVRFSKNGERANNGKNIDEYRSCTNVVYEGSVEKENLTNVQRKKFKCELCSKLFSQKSKLLTHRLSHSSQRPFKCSDCEKAYSTKSKLNAHVRLHTKTNVHSCKLCDKVFAYPSYLREHEKTHDQDNGITNNEGGQSFECSACKKRFRSLKNLRAHERLHTGKGLVQCEICDKRFSQRYNLKIHLRTHKATRPHKCEYCDKCFVQKGNLAEHLRIHTKVKPFECKLCKKRFSQSSHLKNHQSSHTTVRQHQCRLCGKRFKLASHLKRHLILHDGTKAYRCNRCNQLFSQAFSLTRHLKRHESQT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00962657;
90% Identity
iTF_00962657;
80% Identity
-