Basic Information

Insect: Megachile leachella
Gene Symbol: -
Assembly: GCA_963576845.1
Location: OY756255.1:9861071-9862114[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.00027 0.04 15.3 1.8 1 23 68 91 68 91 0.97

2 8 0.0004 0.06 14.8 2.0 1 23 107 129 107 129 0.97

3 8 5.3e-06 0.0008 20.7 1.0 1 23 152 174 152 174 0.98

4 8 0.0036 0.54 11.7 3.2 1 23 182 204 182 204 0.98

5 8 0.00047 0.071 14.5 0.2 1 23 242 264 242 264 0.97

6 8 3.3e-06 0.0005 21.3 0.8 2 23 270 291 269 291 0.97

7 8 2.4e-07 3.7e-05 24.9 0.7 1 23 297 319 297 319 0.95

8 8 0.00011 0.016 16.5 1.0 1 23 325 347 325 347 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.00027	0.04	15.3	1.8	1	23	68	91	68	91	0.97
2	8	0.0004	0.06	14.8	2.0	1	23	107	129	107	129	0.97
3	8	5.3e-06	0.0008	20.7	1.0	1	23	152	174	152	174	0.98
4	8	0.0036	0.54	11.7	3.2	1	23	182	204	182	204	0.98
5	8	0.00047	0.071	14.5	0.2	1	23	242	264	242	264	0.97
6	8	3.3e-06	0.0005	21.3	0.8	2	23	270	291	269	291	0.97
7	8	2.4e-07	3.7e-05	24.9	0.7	1	23	297	319	297	319	0.95
8	8	0.00011	0.016	16.5	1.0	1	23	325	347	325	347	0.98

Sequence Information

Coding Sequence: ATGCTGCGTCAGATACTTTCGCCATCGCCCGAGACGGGGGACCCCGGTCTGCCCGTCACTTGTACCCTGCTCCAGAACAACTCGATGTTCTCGAATCAGTCATCGATGATGCCCTCGACGTTCCAAACGATCCCGTCCCACTTGCCATCCATCTGTTCCGACCAGGGTCTCATGGACCACGTGCAGTTCGTCACCGAGTCCCATCCTTGTTCCACGTGCGGCCTCGAATTCCGAAGCACCCTGAAACTGAATTACCATATAAGAACCAGTCACCCCACTCTGCCGGAATTCGAGCACAGTATAGAGAACCCGATGAGGTATTCGTGCACCATTTGCTCGCGGAGCTTCTTCGCTCTCAGCCACCTGAGAATGCACGAAGTGACTCACTCGGTGCCGGCCACGTCCTGCGCCTCGGTTCCGACGATATCGACCTCGATCAACGTCGAGAAGACGTTTGTCTGCGATCGTTGCCCGGCCAGTTTCCGCTACCGTACGCTCCTCGAACGACACAGGAGGATGCACGAGGTCGGCCAGGAGAAACCTTACTCCTGCCCTAGGTGTCTGATGCGCTTCGAGACCCGAAATCTGTACAATCATCACGCGAAAACTCACAAGCCCGTGCTAACGGGGAATAATAGAATCACCGACACCGTTGGCTCTTCCGGTGATCCGGTGACTAGCAGTATTAGCGGCACCCTGGCGACGTCCAAGTCGATTGTCTCGTATCCGTGCGACTCGTGCTCCAAACAATTCGCGACGGTCGAATCTCTGACCACGCATAAGGCTGTGCACAGGTCCAGACCGCTCGTTTGCGACGTCTGCGGCAAGGGTTTCACACATCGCAAGTATTACGTGGTGCATCAACGCATTCACACCGGGGAGAGACCGTATCTTTGTGCCATGTGCGGGAAGTCATTCACTCAGGCATCCACGCTTACCGTCCATCGGCGATATCACACGGGAGAACGACCTTACACGTGTACCTTGTGTGGTAAAGGATTCGTCACCAGAACCATCATGCTGAATCACATGAAAAAGCATTAG
Protein Sequence: MLRQILSPSPETGDPGLPVTCTLLQNNSMFSNQSSMMPSTFQTIPSHLPSICSDQGLMDHVQFVTESHPCSTCGLEFRSTLKLNYHIRTSHPTLPEFEHSIENPMRYSCTICSRSFFALSHLRMHEVTHSVPATSCASVPTISTSINVEKTFVCDRCPASFRYRTLLERHRRMHEVGQEKPYSCPRCLMRFETRNLYNHHAKTHKPVLTGNNRITDTVGSSGDPVTSSISGTLATSKSIVSYPCDSCSKQFATVESLTTHKAVHRSRPLVCDVCGKGFTHRKYYVVHQRIHTGERPYLCAMCGKSFTQASTLTVHRRYHTGERPYTCTLCGKGFVTRTIMLNHMKKH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00684342;
90% Identity: iTF_00230856;
80% Identity: -