Basic Information

Gene Symbol
-
Assembly
GCA_963576845.1
Location
OY756251.1:17884524-17888976[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 21 1.6 2.4e+02 3.4 3.9 2 23 312 334 311 334 0.96
2 21 0.013 2 10.0 4.8 1 23 384 406 384 406 0.98
3 21 0.11 17 7.1 0.9 1 23 455 477 455 477 0.97
4 21 0.093 14 7.3 2.2 1 22 532 553 532 556 0.90
5 21 2.4 3.6e+02 2.9 1.7 1 23 565 588 565 588 0.83
6 21 0.00045 0.067 14.6 1.3 1 23 593 615 593 615 0.97
7 21 0.00087 0.13 13.7 0.3 1 23 662 684 662 684 0.97
8 21 0.00076 0.11 13.9 0.1 1 23 690 712 690 712 0.97
9 21 1.1e-05 0.0017 19.6 1.6 2 23 757 779 756 779 0.96
10 21 1.6 2.3e+02 3.5 4.9 3 23 788 809 786 809 0.87
11 21 0.00043 0.064 14.7 1.9 1 23 816 839 816 839 0.91
12 21 0.00058 0.086 14.3 0.0 3 23 851 871 849 871 0.92
13 21 0.05 7.5 8.2 0.2 1 20 933 952 933 952 0.97
14 21 0.056 8.4 8.0 0.3 2 23 972 993 971 993 0.96
15 21 3.7e-05 0.0055 18.0 0.7 1 23 1007 1029 1007 1029 0.97
16 21 3.7e-05 0.0055 18.0 6.9 1 23 1052 1075 1052 1075 0.96
17 21 0.037 5.5 8.6 3.4 2 23 1130 1152 1129 1152 0.93
18 21 0.004 0.6 11.6 0.6 2 23 1180 1202 1179 1202 0.94
19 21 0.12 18 6.9 1.0 1 23 1209 1233 1209 1233 0.95
20 21 0.0095 1.4 10.4 1.6 1 23 1238 1261 1238 1261 0.98
21 21 0.12 18 7.0 3.0 2 23 1291 1313 1291 1313 0.92

Sequence Information

Coding Sequence
ATGGACGAAGTGGACGAATTACAAAATATGGAAAGTGTGTGTAGGCTTTGCCTTTCTACCGACGAACCAAAATTGTCGGTATTTGTGGAACAAGAATCCCCGGTATCATTAGCCAATAAAATACAAGCCTGCTTGTCAATTGAGATTTTAGCCACGGACAGGTTGTCAACACAAATATGTGCAGAATGCGTTAAAAATGTGAACCAATGGCATAATTATAAAGAAGCGTGTCTTCGCTCCCAGGATAAATTACGTTCATGGCTGGAAAAACATGTACAAACTGGTCCACTGGTTGTAAGTATTAAGAGTGAACCTATAGATCTGGAATTTTATGAAGATAACATTGAAGTGATCTCTGAATCCACAAATGAGTCAGATTTGGAGCCAACTAATGTTGAAGAAACCCCAAACAATTTGGTAAATAATATCCATGTTCAAGAACTAACTGataatgaaatagaaatagaTAGAGATCGATCAGCATTAACTGATAACGAAACGTATTCGGAGAAAGATCAATCAGTCTTAACTGACAATGAAATATATACAGAGAGAGATCAACCAGTGCTCACTAATAATACAACAGATGTAGAGAGAGATCAGTCATCACTAACTGATAGTGAGATAGATGTAGACAGAGATCAACCATTGTTGACTGATAACGAAATAGATATAGAAGGAGATCACCCAACACTCTCAAAAGAAATAGATATATCTATTAAATTAGAGCCACAAGAGGACTATGATACAGATTGTACTATAGAGATAGAATCTGTTACAGGTGGTGAACTACCGAATCAGCTTCCAAATAAGGAAGATACAGTTATGGAAGCAGATTCTACACAAAAGTTTAATGCATCTGCTACAGTAAACAAGAAAAGAACTAGACGGGGTCCGCACACCCACTTTAGAGGAACAAAAGTTTTTAAACAGAAATGTGTACATTGTCAAATTATTTTGCATTCTAAGCAGTCTTACGCGAAGCACATGGAAAGATTTCATACCGCCAAACAGAATGGTACTACTGAGCTGACAGAATTACAAGATGGCGAAGAATTGGTCGAAGATTTGGAAGATGAATTGATGAGCATGGAGAAGGATGCTCCCTTGACTCAAGTACAACAGAACATTATCAGTCAATTAAAAACGTATTCGTGTTACACGTGCCAGCAACACTTCAGCGATCGTAGGAACACGCTTAATCATATTCGTCAACACATGCCCGATTTAAGACCGTACACGTGCATTGCATGTATGACAGAGTTCCCAGATCGATCGATGTTCAAGCTTCACTGCGAAGTGTCGTTTGAATGTGCAATGAAAATTGCGTTGGTTATACCAAAACAGGGCGAGGAGAAGTACTTCACGTGTAATATGTGCTTGCGCGCCATGCGAAACAGAAGGGAATTACTTAGCCATCTGTCGCAACACTCCGACAAGCAGTACGAGGAGTTGATATCACCTTCACGGTCTCCTCCTAAGTTGAAACCAATGGCACCCTTGCCACCTCCTAAACCAAAACAAACAAATAAAGTGCACGAAGGAGGTCTGCAGATTCCCCAGCCTTACAATAACGGTGATTCTCTGTACAATCACCCATGTGACTTATGCGGAATGATCTATAAGTTCAGACCTAACATGCTGAGGCACAGAAACCTGTGTCTACATTTACCACCGGAGAGCAGGACATCCTACAGATGTGTCCAATGTGGACTAACGTTTCTTGTGTTTAAAAAGTTTCACAGTCACATTGTCATGGACCATAAAAAGAAAGATTTTGTTTGTTCCGTTTGCAACGCCAAATTTAGATCTCCAAGTGACTACCTGACACACCACGAGTCGCATCGTGGTCATAATAAAAAGCCGTCGGTTGAAAACAATCACGAATCAATGACGACCATGCCAAACATATCAACGCCTATCAAAGACTGGGACACCTTTGAGGCTGAAATAAACGCGAACAAAATAACCAATAGCAATAAGTACAGTTGTGCTCTTTGCAACCTGGAATTTGCTACCAGAACCGAGCTAACAGAGCACAGGAATCTTCACCTGAAAGTGAAGATTTACTCGTGCGTTATTTGTCGCAGCATGTTCAGCAGTGCTGGTGCTTTGGAGATCCACATGAAGGACCACGGTATAGAAGATCCAGGCGAAAGGGACGCAAACATCTCGTGTGTGGAATACGGAACGACTAAGAGCGAGGTGGAGGACACAAAGCCATTAAATATGACCGCCGTTTCGGATCCTGGGTCGACCAAAAATAGTAAATGCACCATGTGTAGTAAACAATTCTCGAACTACGCAAACCTCAGACGACACGTAAGAAACGTGCACAAAACAGGTAAACCGTATGTACATTGTCCCGAATGTACTCGGGTGTTTAGAAGTACCGAATCGTGCCATCGTCATGTGACGTTGCAACACAAGTCCTCAAGGACGTTGTACCAGTGTCCCCAATGTCCAAAGACCTTTGTTTTCAAAGCAAACATGAATCTTCATTGTCGGAATGCGCATAACAACGGACGTAACTCGTCCGGTGACTGGGCTTGTGATATCTGCGGAAAAACATTCTACGAAGAAGCGTCTCTGAAGATACACAGGGGCTGGCACAACCGAACTAACTATCGGTTGATCGCCGATATCGCACAGGAAGGAGGAGATCAGAAGCGGGTGAAACAGTTCAAACATCCTTCGTCCAAAACTGATCAGTCGCCAACCACAGCGAACTCGAGTCGGCCGGCTAGGGCGAGGAAATCCTTCCCCAGCCCGGCATCGTCGAAGGGCAGCGGTAATTTCCAATGCCAAGTTTGTAACGATAAATTCAACGACGTGGTGGAGCTGCGGAAACACTTGTGGGATGTCCATTGCGCCCGCAACAAGTCCGAAAAGAATTTCACCGACGTCAAACTGCAGTGCGACCTTTGCACACATATCTTACCCAGCCAGGAGGCGTTCAACATGCACATGCAGTGGCACAAAATTCACCCCATTCTGACCGAGGTCAACAAATCTGCCTTCCCTTGCGACATCTGCGGTAAAAACTACAGTTCCAAGAAGGTATTGTGGAGACACAAGAAGCTGCACAAAGCCACGGTGGTAGCCGCTTCCAAGTTCCAGTCCATGTCCAGAAAGCCTACCGTGTCGAGTCAGTACACGTGTCACACTTGCCACAAGTCGTTTAGCAGTAACCAGTCGCTACAGCGTCACAAGATGAATTTGCACATGGACATGTTCAACGAACGAGCGCCAACGTTGTTCAATAACACGGCGAAAATGTCACCGGTGGAACCAAAACCGAAGAAAGTGAAGTTGGAAGCGGAAGACGTGACGCAGAAGTCAACGACTGTCCTGAACACACTGCGCACCGGCGGCAAGAAGGCTGTGATGTGTCATGTTTGCAAAAAATTCTTCCCTAATATGAGCGTACTCTACAAGCACAAACAGCACGCTCACACCAAGGCCCGCACGGTGAAGAACGTCGCGAAGAGCCCAACCATGGAGCTAATTCCGTTGGCCGGTCCAGAGGGAAGGATGTCTTGCAACATTTGTTTCAAAGAGTTCCCTGGTGTGTCGAACTTGCGGCAGCACTTCAGCATGAAGCATAAGAACAACACGCTCAAGTACATCTGCTCTTTCGAGGGTTGCAAGCTGATGTTCCACACGACGGTAGCACTGAAGAACCACGAGCTATCGCACACTTCTATGATCTACAGCTGCAATCTGTGTGACCGGCACGTGTTCACTAAGCAAGCCATGTCCAGCCACATGCTGACCGTGCACAAGACTATCTACCACGCTGAAGAGAACAAAAACTTCCACAGGGAGACGGATCTAAGCACCTACGTGGTAGAAGGTGCAACGGACGCGACTTGTCCTCATTGCAAGATCAAATATCCCAACAAGAAAGCCATGAAGATTCACTTCTTCAAGTTCCACGATAGCGCGGATCGCTAG
Protein Sequence
MDEVDELQNMESVCRLCLSTDEPKLSVFVEQESPVSLANKIQACLSIEILATDRLSTQICAECVKNVNQWHNYKEACLRSQDKLRSWLEKHVQTGPLVVSIKSEPIDLEFYEDNIEVISESTNESDLEPTNVEETPNNLVNNIHVQELTDNEIEIDRDRSALTDNETYSEKDQSVLTDNEIYTERDQPVLTNNTTDVERDQSSLTDSEIDVDRDQPLLTDNEIDIEGDHPTLSKEIDISIKLEPQEDYDTDCTIEIESVTGGELPNQLPNKEDTVMEADSTQKFNASATVNKKRTRRGPHTHFRGTKVFKQKCVHCQIILHSKQSYAKHMERFHTAKQNGTTELTELQDGEELVEDLEDELMSMEKDAPLTQVQQNIISQLKTYSCYTCQQHFSDRRNTLNHIRQHMPDLRPYTCIACMTEFPDRSMFKLHCEVSFECAMKIALVIPKQGEEKYFTCNMCLRAMRNRRELLSHLSQHSDKQYEELISPSRSPPKLKPMAPLPPPKPKQTNKVHEGGLQIPQPYNNGDSLYNHPCDLCGMIYKFRPNMLRHRNLCLHLPPESRTSYRCVQCGLTFLVFKKFHSHIVMDHKKKDFVCSVCNAKFRSPSDYLTHHESHRGHNKKPSVENNHESMTTMPNISTPIKDWDTFEAEINANKITNSNKYSCALCNLEFATRTELTEHRNLHLKVKIYSCVICRSMFSSAGALEIHMKDHGIEDPGERDANISCVEYGTTKSEVEDTKPLNMTAVSDPGSTKNSKCTMCSKQFSNYANLRRHVRNVHKTGKPYVHCPECTRVFRSTESCHRHVTLQHKSSRTLYQCPQCPKTFVFKANMNLHCRNAHNNGRNSSGDWACDICGKTFYEEASLKIHRGWHNRTNYRLIADIAQEGGDQKRVKQFKHPSSKTDQSPTTANSSRPARARKSFPSPASSKGSGNFQCQVCNDKFNDVVELRKHLWDVHCARNKSEKNFTDVKLQCDLCTHILPSQEAFNMHMQWHKIHPILTEVNKSAFPCDICGKNYSSKKVLWRHKKLHKATVVAASKFQSMSRKPTVSSQYTCHTCHKSFSSNQSLQRHKMNLHMDMFNERAPTLFNNTAKMSPVEPKPKKVKLEAEDVTQKSTTVLNTLRTGGKKAVMCHVCKKFFPNMSVLYKHKQHAHTKARTVKNVAKSPTMELIPLAGPEGRMSCNICFKEFPGVSNLRQHFSMKHKNNTLKYICSFEGCKLMFHTTVALKNHELSHTSMIYSCNLCDRHVFTKQAMSSHMLTVHKTIYHAEENKNFHRETDLSTYVVEGATDATCPHCKIKYPNKKAMKIHFFKFHDSADR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00962002;
90% Identity
iTF_00963365;
80% Identity
-