Basic Information

Insect: Megachile leachella
Gene Symbol: -
Assembly: GCA_963576845.1
Location: OY756247.1:26518045-26521444[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.00041 0.062 14.7 4.1 1 23 228 250 228 250 0.97

2 11 1.3e-05 0.0019 19.5 1.5 1 23 256 278 256 278 0.98

3 11 0.00096 0.14 13.6 3.8 1 23 284 307 284 307 0.95

4 11 0.013 1.9 10.0 5.2 1 21 313 333 313 335 0.95

5 11 0.00013 0.019 16.3 1.9 1 23 341 363 341 363 0.99

6 11 7.3e-05 0.011 17.1 0.8 1 23 369 391 369 391 0.98

7 11 0.00032 0.049 15.0 1.4 1 23 399 422 399 422 0.97

8 11 3.5e-05 0.0052 18.1 2.6 2 23 429 450 428 450 0.97

9 11 0.00013 0.019 16.3 0.3 1 23 456 478 456 478 0.99

10 11 0.0034 0.51 11.8 7.3 1 19 484 502 484 507 0.91

11 11 1.4e-07 2.1e-05 25.6 1.2 1 23 521 543 521 543 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.00041	0.062	14.7	4.1	1	23	228	250	228	250	0.97
2	11	1.3e-05	0.0019	19.5	1.5	1	23	256	278	256	278	0.98
3	11	0.00096	0.14	13.6	3.8	1	23	284	307	284	307	0.95
4	11	0.013	1.9	10.0	5.2	1	21	313	333	313	335	0.95
5	11	0.00013	0.019	16.3	1.9	1	23	341	363	341	363	0.99
6	11	7.3e-05	0.011	17.1	0.8	1	23	369	391	369	391	0.98
7	11	0.00032	0.049	15.0	1.4	1	23	399	422	399	422	0.97
8	11	3.5e-05	0.0052	18.1	2.6	2	23	429	450	428	450	0.97
9	11	0.00013	0.019	16.3	0.3	1	23	456	478	456	478	0.99
10	11	0.0034	0.51	11.8	7.3	1	19	484	502	484	507	0.91
11	11	1.4e-07	2.1e-05	25.6	1.2	1	23	521	543	521	543	0.98

Sequence Information

Coding Sequence: ATGACAAGCAACGTAACGACTATTAAGTTAGAAGAAGGACAGGAATCTGTAACAGAAATACAAACATATTTAGAAACATTCAACAAGGAAATAGAAGGGGGTCAAGGAGAGCAGTTGCAACATGTACAGTTGCAACAAGTGGAAGGACTATCGGGTGGTGAAGAAGGTGGAACTTATTTTGTTGATCAATCTGGTCAATATTATTACCAAGCAAATAATGATGAAACACCTGTGATGACACAAGTGCAAATTCAAGAAGTAGAAGAAGCTGATGTACAAAATGAAGGAGAACATCCTCAAGAAGAACAGTACcaagaaattgaagaactgGAAAATGTTGATGGAGAAGAAGATGGCCAGGTGGCTAATAATGGAAACAATCAAGTTGTAATCAATTCTGGGGATGCATATCAAACTGTTACCATTGTACCATCAGACACTAATCCTGGAGAAGTTAGTTATGTATTGATAGTTCAACAACCTGATTCTGAAGATAAGGAGAGTAGACCTGTAGAGCGGGAAGGAACAGAGGGTGAAGAAGGAGAAGGTGAACAAGACCTTACTGTTTATGATTTTGAAGACAATGAAGACAATGAGGCACCCGTTGAATCAGAAGCAGAAGATGATAAAACCAAAATTATCAAGTTCCTACCTAAAAAATCTCAAACTGTTACCCAAGCTCATATGTGTAATTACTGTAATTACACGAGTCCGAAGCGGTATCTATTATCACGACACATGAAATCGCATTCGGAAGAAAGGCCACACAAATGCAGCGTTTGTGAAAGAGGATTCAAAACATTAGCTTCGCTCCAAAACCACGTTAACACGCATACCGGGACCAAACCACATCACTGTAAATTTTGCGACAGTGCATTCACAACTTCTGGTGAACTTGTCAGACACGTTCGATACAGACACACGCATGAAAAACCGCATAAATGTCACGAATGTGATTATGCATCCGTTGAATTGTCTAAACTGAAACGTCATATTAGATGTCATACAGGGGAGCGACCATATCAATGTCCGCATTGTACATATGCAAGTCCCGACacgttcaaattaaaacgacATTTGCGTATACATACAGGCGAAAAACCATATGAATGTGATTTTTGTCAAGCAAGGTTTACTCAGTCTAACAGTTTGAAAGCTCACAAATTGATACATAATGTTGGAGATAAACCAGTATTTCAATGTGAGTTATGTCCAACGACTTGTGGAAGAAAGACAGATCTCAGAATTCATGTACAAAAATTACATACCTCTGATAAACCTTTAAAGTGTAAGCGCTGCGGAAAAACATTCCCAGATAGATATAGCTATAAGCTGCATAGTAAAACCCATGAGGGAGAAAAGTGTTATAAATGTGATTTATGTCCATATGCATCAATATCTGCACGTCATCTTGAAAGCCATATGTTAATTCACACAGATCAAAAACCATATCAATGTGATCATTGTTTTCAATCATTCAGACAAAAACAGCTTCTCAAACGGCACTGTAATCTTTATCACAATCCTTCTTATGTTCCTCCACCACCGCAAGAGAAGACACATCAATGTCCCGAATGTGAACGGCCGTTCAGGCacaagggaaatcttattcggcATATGGCTGTTCACGACCCAGAATCATCACTTCAGGAAAAGCAACAAGCTTTAAAAATGGGTAGACAGAAAAAGATTCAAATTATAGATGGTCAGAGAGTCGAGGTCATGACAGGTGATTTAGCTTCTAAACTTAAAGgttacgaagaagaagaagaagatgaagacGACATGATGGCTGTCGAAGGAAGCGATGGTCAACAGTATGTTGTATTGGAAGTTATTCAGCTGGCTGATAATCAAGGAACCGATCAACAAATGGCGGTCGTAGCTAGCGAagatggagatttggtgatGCAAGATCCCTTGAGCCAAGAGAGTGGTATCGTAACGGGTACGGGGGAAGAAgtagacgaagaagaagaaaccgaaattgaattaaaaatagatCCGGAACCTACCAATAAATCTTCTCAAAACACTCAAAACGATCCAAAGTTACAAAAAGAAATGGAAACCTGTTTCGGTTTCGACGAAgaggaagaagaggaggaagaggaaCCTAATggcaatataaatatattgcaaacaatttcGTAA
Protein Sequence: MTSNVTTIKLEEGQESVTEIQTYLETFNKEIEGGQGEQLQHVQLQQVEGLSGGEEGGTYFVDQSGQYYYQANNDETPVMTQVQIQEVEEADVQNEGEHPQEEQYQEIEELENVDGEEDGQVANNGNNQVVINSGDAYQTVTIVPSDTNPGEVSYVLIVQQPDSEDKESRPVEREGTEGEEGEGEQDLTVYDFEDNEDNEAPVESEAEDDKTKIIKFLPKKSQTVTQAHMCNYCNYTSPKRYLLSRHMKSHSEERPHKCSVCERGFKTLASLQNHVNTHTGTKPHHCKFCDSAFTTSGELVRHVRYRHTHEKPHKCHECDYASVELSKLKRHIRCHTGERPYQCPHCTYASPDTFKLKRHLRIHTGEKPYECDFCQARFTQSNSLKAHKLIHNVGDKPVFQCELCPTTCGRKTDLRIHVQKLHTSDKPLKCKRCGKTFPDRYSYKLHSKTHEGEKCYKCDLCPYASISARHLESHMLIHTDQKPYQCDHCFQSFRQKQLLKRHCNLYHNPSYVPPPPQEKTHQCPECERPFRHKGNLIRHMAVHDPESSLQEKQQALKMGRQKKIQIIDGQRVEVMTGDLASKLKGYEEEEEDEDDMMAVEGSDGQQYVVLEVIQLADNQGTDQQMAVVASEDGDLVMQDPLSQESGIVTGTGEEVDEEEETEIELKIDPEPTNKSSQNTQNDPKLQKEMETCFGFDEEEEEEEEEPNGNINILQTIS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00730251;
90% Identity: iTF_01421078;
80% Identity: iTF_00961998;