Basic Information

Insect: Megachile leachella
Gene Symbol: mecom-b
Assembly: GCA_963576845.1
Location: OY756251.1:22457166-22461120[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.016 2.4 9.7 0.6 2 23 30 52 29 52 0.92

2 9 0.43 64 5.2 0.1 1 23 59 82 59 82 0.93

3 9 1.4e-05 0.0021 19.4 1.8 1 23 88 115 88 116 0.93

4 9 3.7e-06 0.00055 21.2 2.6 1 23 122 144 122 144 0.95

5 9 2.3e-05 0.0034 18.7 5.0 1 23 150 172 150 172 0.99

6 9 0.00045 0.067 14.6 0.7 2 21 180 199 179 200 0.95

7 9 5.3e-09 7.9e-07 30.1 1.2 1 23 552 574 552 574 0.99

8 9 2.8e-07 4.1e-05 24.7 1.7 1 23 580 603 580 603 0.97

9 9 7.8e-06 0.0012 20.1 3.4 1 23 609 631 609 631 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.016	2.4	9.7	0.6	2	23	30	52	29	52	0.92
2	9	0.43	64	5.2	0.1	1	23	59	82	59	82	0.93
3	9	1.4e-05	0.0021	19.4	1.8	1	23	88	115	88	116	0.93
4	9	3.7e-06	0.00055	21.2	2.6	1	23	122	144	122	144	0.95
5	9	2.3e-05	0.0034	18.7	5.0	1	23	150	172	150	172	0.99
6	9	0.00045	0.067	14.6	0.7	2	21	180	199	179	200	0.95
7	9	5.3e-09	7.9e-07	30.1	1.2	1	23	552	574	552	574	0.99
8	9	2.8e-07	4.1e-05	24.7	1.7	1	23	580	603	580	603	0.97
9	9	7.8e-06	0.0012	20.1	3.4	1	23	609	631	609	631	0.99

Sequence Information

Coding Sequence: ATGTGCCTTTTCTTCTTTGTGCTTGCAGCCTCGCAACACAGCGGCACCGTCGACGAGGATAAAGAGGACGAGGAAGAGGGAGAGACCAGGTGCACCGTCTGCGACAAACCGTTTCAAGACATCGAGCTATTGGACAGTCATCTGGTGTCTTGTCACCGATACCCAGCGGAGCAACATCGCTGCGACAGCTGCCCTCGTGCGTACGCCTGGCGGCCTCTTCTAGTTCGACATCGCGCGATCGTGCACGGAGATCTTCGAAACTACCCCTGCGAGAACTGTCCAAAGTCGGACAAACCGCAGGTCTTCACGGATCCGTCGAACCTCCAGCGTCACATCAGGACGCATCACGTGGGCGCGAGGAGTCACGCGTGCACCGAGTGCGGCAAAACGTTCGCAACCAGTTCCGGTTTGAAGCAGCACACTCATATCCACAGCAGCGTGAAACCGTTCCAGTGCGAGGTCTGCTTCAAGGCGTACACCCAGTTTTCGAATCTATGCCGGCACAAGCGAATGCACGCGGACTGTCGCATGCAGATCAAGTGCGTTAAATGCGGACAATCCTTCAGCACGGTGACTTCTCTGTCGAAGCAcaagcgattctgcgattccacGCCGCCGACTGGACCACCTGGAGCCATGCCGCAGTTGCCGACTTCGGCACCCAGCCCGTTCATCGTCTACCGACCTCCTGTCAGTCTGCCGGGTAGTCTGCCCTTCTACCCGCCCAGTCTGATGGGTCCGTACCCAGGAATATTCCCGAACGCTCCGAACTTTTTGAATACCCCGCTGCTCTTTCCACCCAAGGTCGAGGAGACCGAGAAGAGAAGCGACAGCCCGAAAAAGGAACGCTTCACTCCTCCGAGAGTGTTACCGCAGCACAGCAAAGTCTCTCCATCCACCGCCGAAGAGGCCACCTCGTCGTTCAGACCTTCTCCCGCTAGACCACCTGTCCAGCCCACTCCGGAGAGCGACGACGACCCTGCGAAAAAACGAAATGCCACCGGTAATAACGAGAAGAAGGATCCCGAACATGCTCCGACAAATTCCAACGAAGAGACGACGGATCAACCTCTGGACCTGAGAGTTCAAACCAAGAAGCAAAAGCCGCCGTCGAACACTGCCGAGAGGAACAGCCACAGTCCTTCGCCTGTTCCGGCACCGATGGAGGAAGCTCCGCCGCCTCCGGAACGTCCGAAGCCCGAAGAAGAAGCTCCTGCACCGATGAACGTCGACGCCAAGGACGTGCCCAGTAGTCCACAGCTGAGGACTAGTTTACCGGAGCAACCACCCACAAATACTCCGCCGCACATGGCTTACCCGAGACCCATTCATCCCATGTTCCTGGAAGCCATGTACCGTGGTCCGACGGGCAGTTTCCCCGGGTTCCCGGGCGGACCACCGCCCCCTGGAAGCGCCACACCAGAATCCAGGTTACTACCACCGCTACCACCGTTCGGGCCACCCCGTGGGCTCCCTTTTTTAGGGACGCTTATGAACGGACTCAGCGGCGCTAGGCCAGGAGGCGGAGGGTTCGACCTGCTTGCTAGGCCGCCGCTGGGACCGTTCCCTGGCGTCAAGCCGTTTCAAGAAGCCGTGATCGCGCCTCACCACCATCACCATCCTCATCACGCCCATGGCAAGATGAAGGACCGATACTCGTGCAAGTTTTGTGGCAAAGTATTCCCCAGATCCGCTAATCTGACCAGACACTTACGGACGCACACCGGCGAGCAGCCCTACAAGTGCAAGTACTGCGAGAGATCCTTCAGCATCTCCAGCAATCTGCAGAGACACGTGAGGAACATCCACGACAAGCAGAGACCGTTCAAGTGTCCCCTCTGCGAGAGATGTTTCGGCCAACAGACCAACCTGGACAGACACCTGAAGAAGCACGAGGCCGACGATGGCAGCGGAGTCGTCTCCGTGGCCGATTCGCCGGGTAGCAGTAACGAGAACGAACGAGAGGACACGTACTTCGACGAGATCAGATCGTTCATGGGAAAAGTGACGTACGGCGGCGAAGCGGGTTACGGAATACCCCCTCATCCTGCTTACCTGCCCAGCCGATTGCACGAGATGCACGAGTCTAAGATGGAAACCGAGTACGACGAAGACGAGGACAGCGAGGAAGGAGTGTCGCCTCTCGACGAAACCGACGGATTGTCCCCCGTCGAGGCGAAGGAATCCACGCCGCCCCCGCAGTACGATCTGAAGCTGAGAGAGAAGCAGATGCTCAACAACAACACCGCGGAGCCGGTCATCGAAATTTCTACATAG
Protein Sequence: MCLFFFVLAASQHSGTVDEDKEDEEEGETRCTVCDKPFQDIELLDSHLVSCHRYPAEQHRCDSCPRAYAWRPLLVRHRAIVHGDLRNYPCENCPKSDKPQVFTDPSNLQRHIRTHHVGARSHACTECGKTFATSSGLKQHTHIHSSVKPFQCEVCFKAYTQFSNLCRHKRMHADCRMQIKCVKCGQSFSTVTSLSKHKRFCDSTPPTGPPGAMPQLPTSAPSPFIVYRPPVSLPGSLPFYPPSLMGPYPGIFPNAPNFLNTPLLFPPKVEETEKRSDSPKKERFTPPRVLPQHSKVSPSTAEEATSSFRPSPARPPVQPTPESDDDPAKKRNATGNNEKKDPEHAPTNSNEETTDQPLDLRVQTKKQKPPSNTAERNSHSPSPVPAPMEEAPPPPERPKPEEEAPAPMNVDAKDVPSSPQLRTSLPEQPPTNTPPHMAYPRPIHPMFLEAMYRGPTGSFPGFPGGPPPPGSATPESRLLPPLPPFGPPRGLPFLGTLMNGLSGARPGGGGFDLLARPPLGPFPGVKPFQEAVIAPHHHHHPHHAHGKMKDRYSCKFCGKVFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNIHDKQRPFKCPLCERCFGQQTNLDRHLKKHEADDGSGVVSVADSPGSSNENEREDTYFDEIRSFMGKVTYGGEAGYGIPPHPAYLPSRLHEMHESKMETEYDEDEDSEEGVSPLDETDGLSPVEAKESTPPPQYDLKLREKQMLNNNTAEPVIEIST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01407591;
90% Identity: iTF_00118172;
80% Identity: -