Basic Information

Insect: Megachile leachella
Gene Symbol: gtf3a
Assembly: GCA_963576845.1
Location: OY756250.1:1143400-1147711[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 0.00074 0.11 13.9 0.1 2 23 733 754 732 754 0.97

2 17 3.8 5.7e+02 2.2 0.9 1 19 760 778 760 779 0.91

3 17 1.3 2e+02 3.7 1.1 3 23 788 808 787 808 0.97

4 17 0.00026 0.039 15.3 1.2 3 23 817 838 816 838 0.98

5 17 0.0027 0.4 12.2 2.0 1 23 845 868 845 868 0.95

6 17 9.5e-05 0.014 16.7 0.7 1 23 874 897 874 897 0.94

7 17 1.3 1.9e+02 3.7 2.5 2 23 905 925 905 925 0.94

8 17 1.4e-07 2.1e-05 25.6 2.1 2 23 931 952 930 952 0.97

9 17 2.2e-06 0.00033 21.8 0.2 1 23 958 980 958 980 0.99

10 17 0.00056 0.083 14.3 2.4 2 23 992 1014 991 1014 0.95

11 17 0.0079 1.2 10.7 2.5 1 23 1020 1043 1020 1043 0.96

12 17 0.012 1.8 10.1 3.0 2 23 1065 1087 1064 1087 0.95

13 17 0.003 0.45 12.0 0.9 2 23 1094 1116 1093 1116 0.96

14 17 5.7e-05 0.0085 17.4 1.0 3 23 1125 1145 1123 1145 0.96

15 17 0.0012 0.18 13.3 2.3 1 23 1151 1174 1151 1174 0.96

16 17 0.33 49 5.6 3.2 2 23 1181 1202 1180 1202 0.96

17 17 0.0095 1.4 10.4 2.6 1 23 1208 1230 1208 1230 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	0.00074	0.11	13.9	0.1	2	23	733	754	732	754	0.97
2	17	3.8	5.7e+02	2.2	0.9	1	19	760	778	760	779	0.91
3	17	1.3	2e+02	3.7	1.1	3	23	788	808	787	808	0.97
4	17	0.00026	0.039	15.3	1.2	3	23	817	838	816	838	0.98
5	17	0.0027	0.4	12.2	2.0	1	23	845	868	845	868	0.95
6	17	9.5e-05	0.014	16.7	0.7	1	23	874	897	874	897	0.94
7	17	1.3	1.9e+02	3.7	2.5	2	23	905	925	905	925	0.94
8	17	1.4e-07	2.1e-05	25.6	2.1	2	23	931	952	930	952	0.97
9	17	2.2e-06	0.00033	21.8	0.2	1	23	958	980	958	980	0.99
10	17	0.00056	0.083	14.3	2.4	2	23	992	1014	991	1014	0.95
11	17	0.0079	1.2	10.7	2.5	1	23	1020	1043	1020	1043	0.96
12	17	0.012	1.8	10.1	3.0	2	23	1065	1087	1064	1087	0.95
13	17	0.003	0.45	12.0	0.9	2	23	1094	1116	1093	1116	0.96
14	17	5.7e-05	0.0085	17.4	1.0	3	23	1125	1145	1123	1145	0.96
15	17	0.0012	0.18	13.3	2.3	1	23	1151	1174	1151	1174	0.96
16	17	0.33	49	5.6	3.2	2	23	1181	1202	1180	1202	0.96
17	17	0.0095	1.4	10.4	2.6	1	23	1208	1230	1208	1230	0.98

Sequence Information

Coding Sequence: ATGCAGCACATTGAAATTAGTAACAAGGATCATAATTATAGTGAAGTAAAATCAGATAATTTTcaacataataatagtaatggtcAAACTGCATGTGACAGTGATGTTAAAACAACAGTGTGTAAATCCAATAAAGAAACGTTTGGACAAATTAAAgacataaatgaattaaagaagATCACACCACGTGTGAAATTATTAACTCATGATGCTAATAGTTTAAATGAATTAACTAAAATTTCATTGCACAATAAAATATCTGCACAAAAAAAATTATCGATATCAGAGCAAACaaaacaaacattaaaaaagTATTGTAGGACCTGTGCTGGTTTAAAGCTTCCATTAGTTGATATTTTTAGTGAGAAAGGTATACAAATGAGATTAAGTCAACAAATTAAACACTTAGAAGAAATAAATCCATATGACAGTTTATCAACTCAAATGTGTATGGATTGTATTTGTGATTTAAAAATgagttataaatttttcatgcaaattaaaaaagcggaagttaaattaaaatccATTCATATTAGTCTAACTGACACAGCAACAAAGAACATAGAAGTAAATAAGATACAACCTGTAGAGAGTTCAGAAAAACAGGTAGAAAATGTGGAATGTAATTCTATGAATCCGTCTACAAGTAAGGAACATAATGAGCAGGTACTTGTACCAAAAATACCTGCAAATGTTTCATTAAAAGTTGAATCAGAATCTTTAAAAGATgaagaaattaatattgaagaatttgaaaataaacctgaacttgaaatttttgaagaaacAATAGTCCAGCATAACAGCGATGACAATGAATCTATAGAAGAGTTTGATCCAGATGATCCTCCTTTTCAGCCTGATAGTTCTGATGCCGTAGAATCTGATGATGACATAGATCTACAAACACCGGTTATAAAAAGACGGAATACTCAACAGAAAGAAATTGTTACAAAACATTGTTCTCAACCAATGTCTATTCGTGATCATAAATCAATTTCAGATAGTGGAAATACTGATTTTAATCAAACAACATATAAGTATGATTCGTGTCTAAAAGCATACATTAAAGTTGAGAATATAGAAGGTAATAATCTTTCTTCTGAAccacaaaatataattaaaacagaAACTGTTTCTAATACTGATAGTACAAAAGAATCCACAAAACAACCAAACATATTAAAACGAAGACTTTTATTACAAACTAAAAAAGATTTTTCTGAAGAAACAGATGAAAGTATTCATCAGTCTAGTGTTTCTGAAAAAGGTGGAAGCCATAAAGATtttaaagtacaaaaattagatGTAAATAATTCTTTGAACATTAATAGCAATCAAGAAGATGGAATTATGTATGTTACAGTGAAGGGATCTAAgccaaatgaaatattattagtaaaagttaaaaaaatggATAAACCATTAGAAAAGAAAGATGATAAATCTTCGGGgaaaaaaaattttgatataaaaccaatggaaaaaatttttaaacgctATGAAACATTAGTTACAAAAGAAAAGGATTTATTTCCCGAACGGACAAAAAAATCGGAAATAAGAGAGCAGATTATAGAAGAGCAAATAGAAGAGTATAAAAAAAAACGGGAGAAGGTATTAGGTGGGCATGCTAGTATTTCACTTCCTTTAAAGCCTGAAGAAACACAAACTCGATACTTTAAACGTAATGAAAGCCAAGATAACCAGAAATCTTCCATGCAAACAGAAAATGATTTGATTGCAAGTGTAtgtgataaaaatgaaaatgaatctaaaatgaatgttattaaaaatgaaaatgaaacacTGAATATTGTAGAACCAGTAAAAGAAAAATCTAGTAATGAAAAAGCATATGTAAATACTGAAGAGTATTTATCGCGTTTAgcaaaacttaaattaaaatggGAAGAAGCAAAGAAGAAAAAGGAGTCTCTTCAAAAAGAACTCGATGAGTCTTACACAGAAGGAAATATTGAAAAGTTGGCAAGAATTTtgggagaaaaagaaaaaaatttgcaagattttcAAGATTATTTGAAGCAAcgtaaaattgtaattacaagATTAAAAGATGAAGATATTATTTCTCTTTATGAAGACAGAAATAATGCAGTGCTTAAAAACAATTTACCTGATTTAATAGATGAAAGTCAACCAGCAGATTATATTCCAGAAGAACATTATTTGGAATGCGATTACTGTCCAGAAACATTTGCTTCTAAAGATATACTTGAGGAACATTTAAAGATGcatgattataaaattatgcaTTTTTGTGAAGATTGCTTGGAAGAATTTCCAACGAATAAAGCAAAACGAAATCATAATGTAGTCTGTATAAAAAAGTTGTTATGTAAGTATTGCGACATGATATTGGATTCAAAAGGGAAAAAACGCCAGCATGAACAAAAACATTGTGACAGTATGTATGGTCAATTATGTGATGTATGTGGTGAAAAGTTTAAACATCAAGGAACACTGGATCAGCATGTAAAAACGCAACATATGAGTTGGGAGAAAATATATCAATGTCCAAAGTGTCCAAAAAAATTTGCATTCAAGCAGAAACTTAGTTTTCATTTAAAATCTGTACATACAACATTAAGGGCCTATTTATGCGAGGATTGCGGAGCAGACTTTAAAAATCCTGCAAGTCTTAGACATCATAGAATACGTAAACATCAACCAGTAGGCAATAAAAGAGAATGTCCAGTTTGTCATAAATTAGTTCCATTTTATAGCCTGTCCAAACATATGCATACTCACAAAGCATATACTATTCAATGTCCACATTgtgataaaatgtttaaaaatagttcCACTTTAAAACAACATGTCAGAATTCATGAAGACCAACGTCAATATCGATGTGACACTTGCGGAGTTGGATTCAACAGGCGAGATGGCTTAAGATTGCATATGAGAGTGCATGAAAAAACTGATAGTAGAGGACTGAAAGAATGTTCATGTCAGGTATGCGGTGAAAAGTTCCCAAATCATTCAACGCTTGTTATACATCGAAATCGGGTTCATAAAGATGGTAGACAATATACATGTCATATATGCAATAGATCAATGATTTCAACTAGATCTCTGGAATGGCATATGTCTCACATACACAATGAATCCCTTCCTGGTGTTATAAAAGAAGATGTGGATGGAACACCAGAAAAGAAAAGAGTATCATGTtatcactgtaataaaacatttaaaacaGAAATGATTTTAAGAACGCATATTAAAAACACTCATATGGAGAAAGATCCAATGAAGTGTTTAGATTGTGAATTAACATTCATTTCTGAAGTAAGATTGAGACATCATATGATGGTGACACATAACAGACTAgaaggaactttggcatgtccACATTGTCCCAAAAGATTTGTGAATCAACTTAGGTTGAAAACACATATGATATCTCATTCTGAAGAAAGACCATATACAtgtgaaatttgtggatttaatttgaaaacaaaaataCAATTGATTAAACATCATCAAAATAGACATAGCGATGAGAGACCTTTACAGTGTAGATATTGTCCTTGGAGATGTAAACAAGTTAGTGCTCTTGTATGCCATGAAAGAACTCATACGAATGAACGACCATACTCTTGCAGCGTGTGCAGGCAACGTTTCAAATATTTAGGTGACAAGAATAAACATGAAAGGAGACATGAAAGTTTAGGAGGATCTGGGTTCAAAAGAATAGTGCCTGGTAGAAACATTAAACCTAAAGTTCAAGAAGATTCTTCTTGTTCTGAACATGAACAGGAGAGTTTAACTAATGCTGAACATCAGATCACTGAAGGTGAATACGAGGAACAAACTAATCAGCAATTCGAAGAAGAGCAGATAGTTAAGTTTGAGGAACAAGAAATAGTGAAGTTTGAAGAACAAGAAATAACAGAAGAATATGAGCAAGTATATGAAcagGAATATGAAGAGACATCTAGGGAAGCTTCGGATGCAGCAGAAGTGATAATGAATATGGAAGATACCACTGTCTATACTGAAGAAGTAACAGCAGATAATATTGAACCTACAGAAATAATGACGGATGAAATTATGacaaatgaaatattacaatCAGGTGCTGTGGTTCATCTGCAGCAAGAAGATGATTCAGGAAAGATACAAGTGATCCCAGTTATGTTATCTTTGCCTGATCTCTCTGATGCAAATACAGAGGTCAATTTAGCTACAGCATCcattatgtataataactga
Protein Sequence: MQHIEISNKDHNYSEVKSDNFQHNNSNGQTACDSDVKTTVCKSNKETFGQIKDINELKKITPRVKLLTHDANSLNELTKISLHNKISAQKKLSISEQTKQTLKKYCRTCAGLKLPLVDIFSEKGIQMRLSQQIKHLEEINPYDSLSTQMCMDCICDLKMSYKFFMQIKKAEVKLKSIHISLTDTATKNIEVNKIQPVESSEKQVENVECNSMNPSTSKEHNEQVLVPKIPANVSLKVESESLKDEEINIEEFENKPELEIFEETIVQHNSDDNESIEEFDPDDPPFQPDSSDAVESDDDIDLQTPVIKRRNTQQKEIVTKHCSQPMSIRDHKSISDSGNTDFNQTTYKYDSCLKAYIKVENIEGNNLSSEPQNIIKTETVSNTDSTKESTKQPNILKRRLLLQTKKDFSEETDESIHQSSVSEKGGSHKDFKVQKLDVNNSLNINSNQEDGIMYVTVKGSKPNEILLVKVKKMDKPLEKKDDKSSGKKNFDIKPMEKIFKRYETLVTKEKDLFPERTKKSEIREQIIEEQIEEYKKKREKVLGGHASISLPLKPEETQTRYFKRNESQDNQKSSMQTENDLIASVCDKNENESKMNVIKNENETLNIVEPVKEKSSNEKAYVNTEEYLSRLAKLKLKWEEAKKKKESLQKELDESYTEGNIEKLARILGEKEKNLQDFQDYLKQRKIVITRLKDEDIISLYEDRNNAVLKNNLPDLIDESQPADYIPEEHYLECDYCPETFASKDILEEHLKMHDYKIMHFCEDCLEEFPTNKAKRNHNVVCIKKLLCKYCDMILDSKGKKRQHEQKHCDSMYGQLCDVCGEKFKHQGTLDQHVKTQHMSWEKIYQCPKCPKKFAFKQKLSFHLKSVHTTLRAYLCEDCGADFKNPASLRHHRIRKHQPVGNKRECPVCHKLVPFYSLSKHMHTHKAYTIQCPHCDKMFKNSSTLKQHVRIHEDQRQYRCDTCGVGFNRRDGLRLHMRVHEKTDSRGLKECSCQVCGEKFPNHSTLVIHRNRVHKDGRQYTCHICNRSMISTRSLEWHMSHIHNESLPGVIKEDVDGTPEKKRVSCYHCNKTFKTEMILRTHIKNTHMEKDPMKCLDCELTFISEVRLRHHMMVTHNRLEGTLACPHCPKRFVNQLRLKTHMISHSEERPYTCEICGFNLKTKIQLIKHHQNRHSDERPLQCRYCPWRCKQVSALVCHERTHTNERPYSCSVCRQRFKYLGDKNKHERRHESLGGSGFKRIVPGRNIKPKVQEDSSCSEHEQESLTNAEHQITEGEYEEQTNQQFEEEQIVKFEEQEIVKFEEQEITEEYEQVYEQEYEETSREASDAAEVIMNMEDTTVYTEEVTADNIEPTEIMTDEIMTNEILQSGAVVHLQQEDDSGKIQVIPVMLSLPDLSDANTEVNLATASIMYNN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00684931;
90% Identity: iTF_00961995;
80% Identity: -