Basic Information

Insect: Megachile leachella
Gene Symbol: -
Assembly: GCA_963576845.1
Location: OY756259.1:15666937-15670855[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 2.5e-05 0.0038 18.5 0.7 1 23 146 168 146 168 0.95

2 15 0.00088 0.13 13.7 1.0 3 23 176 196 175 196 0.99

3 15 8.1e-05 0.012 16.9 0.0 1 23 319 341 319 341 0.98

4 15 9.9 1.5e+03 0.9 0.1 1 21 347 367 347 370 0.65

5 15 3.1e-05 0.0046 18.3 2.0 1 23 396 418 396 418 0.98

6 15 1.7 2.6e+02 3.3 0.0 1 23 433 455 433 455 0.86

7 15 0.53 80 4.9 0.4 2 23 462 484 462 484 0.94

8 15 0.004 0.59 11.6 3.0 2 19 492 509 492 513 0.95

9 15 0.0002 0.029 15.7 3.5 3 23 521 541 519 541 0.97

10 15 0.014 2.1 9.9 0.1 3 23 548 568 547 568 0.97

11 15 8.2e-06 0.0012 20.1 0.4 1 23 577 599 577 599 0.98

12 15 0.0036 0.53 11.8 0.2 3 23 607 627 605 627 0.97

13 15 0.0032 0.47 11.9 0.2 3 23 635 655 633 656 0.94

14 15 1.1 1.6e+02 4.0 0.0 1 23 670 692 670 692 0.92

15 15 0.0025 0.37 12.3 0.0 1 20 1068 1087 1068 1090 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	2.5e-05	0.0038	18.5	0.7	1	23	146	168	146	168	0.95
2	15	0.00088	0.13	13.7	1.0	3	23	176	196	175	196	0.99
3	15	8.1e-05	0.012	16.9	0.0	1	23	319	341	319	341	0.98
4	15	9.9	1.5e+03	0.9	0.1	1	21	347	367	347	370	0.65
5	15	3.1e-05	0.0046	18.3	2.0	1	23	396	418	396	418	0.98
6	15	1.7	2.6e+02	3.3	0.0	1	23	433	455	433	455	0.86
7	15	0.53	80	4.9	0.4	2	23	462	484	462	484	0.94
8	15	0.004	0.59	11.6	3.0	2	19	492	509	492	513	0.95
9	15	0.0002	0.029	15.7	3.5	3	23	521	541	519	541	0.97
10	15	0.014	2.1	9.9	0.1	3	23	548	568	547	568	0.97
11	15	8.2e-06	0.0012	20.1	0.4	1	23	577	599	577	599	0.98
12	15	0.0036	0.53	11.8	0.2	3	23	607	627	605	627	0.97
13	15	0.0032	0.47	11.9	0.2	3	23	635	655	633	656	0.94
14	15	1.1	1.6e+02	4.0	0.0	1	23	670	692	670	692	0.92
15	15	0.0025	0.37	12.3	0.0	1	20	1068	1087	1068	1090	0.94

Sequence Information

Coding Sequence: ATGGATGTTGCTGGAGATTTGACATTACAATGGGTAGAGGAGGTGGGAAACGTGATCCACGAAGAAGTGATATGCGGTTTAGAGGCACAGTTAGTTGGAGCGGAAGAAGAGGTGATAGGTGCTTGCGAGGAAGTCGCGGTCGAGGAAACAGTGGAAACTGTTCCCGATGTTGCTCCTACAACAGAGTCAGAAATATTAATGGTACCCCAGTCCAATGACATGGAATCTATTTACATAGTGCCACAGGATCAAGGTCATGATTATTTGAATATACAAGTTACGGAAGAAGTGATCGCAGATAATTGGGATAGATCTGGTCCGGAAGATGGGGTTGAGATATCAGAAACGAAAGTGTCGCATGAAAACTTGTTGGAATACGATGACATGGAAATACCATTACCGATTGATCAAGATTCTTATACAAATAGTAGACCTTACCCGTGTGACTTTTGTAGCAGAAGGTTCAGGAAAAAAGCAAATTTAATGAATCACATGGTGGCGCATCAAACAGATCGTCCTCATGGTTGTAATTTATGTGGAGCACGTTATGCACGTAAGTGTGATCTCATGaatcatttgaaaattcatgCGTATGCGCCATCTCGAGATGGTTTGGAAGATGATTTAAACGACGATGACTCGTTGGTGCCGGAAGAGGAAGAGTCTACTAAGGGTAGACGTAAGAAGGTACAATCAAGCGTACCAAGAAAACGAAAAAATCATTCTGCTATTTCAAAGCGCAGCATGGACGAtaataaaatggaaatgggCAAGTATGTCAATAAATCTTACGATTACGTTGACGAGGATATGCGCCTTTTGGAAGAGATGACCAGTAGAAATTCTGCGCGTAGTAGTAATTATGCATCAAGCTCAAGATGGAACGATCAGATGTCACCCGTATCAACTGAACCTCAGGCACCACGGTGGCCTATAACCGATCCGACAAAACCATACGTATGTCAGTATTGCGGCGTTGGTTTTGCAAGGGAAAAGGCACTCGCGTCTCATGCTCGTATCCATGGTGGTGATAGCCCGTTTGAATGTACAACGTGCGGTGATATGTTTTGGGACGTTAACATTCTGAGAGAACATGTACGGGTGAAGCATGGTGGTACGGCACAATCGGATATGGATGAATACGATAATGATGCTACGTATACTGGCGACgaaagatttggagaattttattgCAATACATGCGGTGTACCTTTTCACCGTTTGGATTTACTTAAACGTCATCAAAAGATTCACGTGAAACAAGAAGCTGATATGATGGAAGGTCCAAGTCAACATCATGTTTGCAATGTTTGTGGTGAATGGTTTGAAGAGGCTTTAGCATTATTAGCACATGCCGAACTTCATGCTAGATCGCCCAGTCGTCGATGCTTATTATGCGGTGAAAGGTGTCGTGATGATGCTGAAGTTGCTGAACATGTCCGGCAAAATCATGCCGAAGACGCTCCACCAAATACGTGTACTCTTTGCGGCAAAACGTGTAAAGATAAGCGTAGTTTATTAAAACACTCGTGGGTTCATAACGTTGATAAAACTTTTGGATGTACAAAATGTGGCAAACGTTTCCATAGCAAAGCTAGATTACGAAGACACATGGTATCGCATCGCAATAAAATGGTAGCCTGTGATGAGTGCGGAGAAGAATTTCCTGATGGTAGAGCTCTTGTTAGCCATCGTCATTCGCATAATAAGGAATTGGGCGGTCGTTCTTTTCCATGTCGAGAATGCGGGAAAACGTTCGGCAGTCGTAGTTCACAGCAAATTCATATCCGTATTCACACCGGAGAAAGGCCGTACGGTTGTAGATTTTGTTGGAAAGCATTTGCCGATGGTGGAACCTTACGGAAGCACGAACGCATCCATACAGGCGAGAAACcatacggatgcgcaatttgTCCAAGAGCTTTTAATCAAAGAGTCGTTCTCAGAGAACACGTACGTGCTCATCATTCAGGACCAGATCCAAAATGCGTAGGTAGCATTACACCGTACTTATGTAAAGTATGCGGAGATGCGTATGGAACATCGGAAGAAATAGTTGCTCACATAGTGCAGCATTGTGATGATAATACCGCGTTAAGACGACAACCGCAAACTGGACCGCGTAAATATAAAAGAAGACGTAAACTTAAACCTCATGAAACTAATACGATGTTGCGTATGAACGAACAATACGACATGATGGAGGCTGGTTCCGATTCGGATGACAATACCAAAAGAAAACTTGGAAGGAAAAATAAACAACATCGATCGAACATCGAGGAAGGATATCAAAATGTTCTTAAGAGCTTCGAGAGCTCTTTACAAAACATCAATTCGATTGTTAGTAACTCGAAATTGAATCCAGGAAAATCTAAGCTCTCTAAGAAAAAGCTTagaaaagaagagaagaagagTGAATCGCAAGCCTCGTGTCATCCGGGTAGACCAAAAATGATTCACACCCAAAAAACAAGAGTGCCCGTAGAGATCGGTAGCGATGGAGTTAAAAGAGGACAAAAAACTAAAACTATGGTAACAAGGACACCTAAAATGATGCCACAAGAAcataaattaggaatttttccGGGTGGTGAAAGAAACAGGCCGAGAACGAAAAATGTTAGTTATCATATCGAAGGGAAATTTCAACCGTCAGCCGCAACATTCCCGAAACCAAAGGACGAAATTCCGAGAACACCAACACCGACGCTTCAGCAGTTACCGATAACGCATATAAAACTGGAACCTAATTTGCAGAAAACTCCGAATAATAATCATagaaataataatggtaatattcTTGGCATGAACAATGAAAAGATGGAATCGTCGGGTAGAAAAAAATCCGGTGtattgaagaaaattaaaaagcaaAAAGATGGGATTAAACAAGAGCCAATGGATATTGACCAAGATGagatacaaaataataataatactgaaaGTACCAGCCCCGAAAGGTTAATGGAACATACAGTGGATGGAAACAATTTAGAAGTTGCATTTGAAGCAAGTGTCACAACGGAGGAAGAAAATATTCTTCCCGACGTAGGGGAAGTAAATAATGCCGAGGATGTTGGGACCGGGAATGTTAAACTTAGTGTCAAAGTTGAATCAACGCCTCAACGAATGTTGGCTGTCCATAGTGTTATAGCGCCGGTGGATGATATTCCAGAAACTATAATACCAGATGCTGTTGAATATACATGTGAAATGTGTTCTGCGGTATTCTCTAGCAGAGCAGAATTGTTGGTTCATGTTCCGATACACATTTGA
Protein Sequence: MDVAGDLTLQWVEEVGNVIHEEVICGLEAQLVGAEEEVIGACEEVAVEETVETVPDVAPTTESEILMVPQSNDMESIYIVPQDQGHDYLNIQVTEEVIADNWDRSGPEDGVEISETKVSHENLLEYDDMEIPLPIDQDSYTNSRPYPCDFCSRRFRKKANLMNHMVAHQTDRPHGCNLCGARYARKCDLMNHLKIHAYAPSRDGLEDDLNDDDSLVPEEEESTKGRRKKVQSSVPRKRKNHSAISKRSMDDNKMEMGKYVNKSYDYVDEDMRLLEEMTSRNSARSSNYASSSRWNDQMSPVSTEPQAPRWPITDPTKPYVCQYCGVGFAREKALASHARIHGGDSPFECTTCGDMFWDVNILREHVRVKHGGTAQSDMDEYDNDATYTGDERFGEFYCNTCGVPFHRLDLLKRHQKIHVKQEADMMEGPSQHHVCNVCGEWFEEALALLAHAELHARSPSRRCLLCGERCRDDAEVAEHVRQNHAEDAPPNTCTLCGKTCKDKRSLLKHSWVHNVDKTFGCTKCGKRFHSKARLRRHMVSHRNKMVACDECGEEFPDGRALVSHRHSHNKELGGRSFPCRECGKTFGSRSSQQIHIRIHTGERPYGCRFCWKAFADGGTLRKHERIHTGEKPYGCAICPRAFNQRVVLREHVRAHHSGPDPKCVGSITPYLCKVCGDAYGTSEEIVAHIVQHCDDNTALRRQPQTGPRKYKRRRKLKPHETNTMLRMNEQYDMMEAGSDSDDNTKRKLGRKNKQHRSNIEEGYQNVLKSFESSLQNINSIVSNSKLNPGKSKLSKKKLRKEEKKSESQASCHPGRPKMIHTQKTRVPVEIGSDGVKRGQKTKTMVTRTPKMMPQEHKLGIFPGGERNRPRTKNVSYHIEGKFQPSAATFPKPKDEIPRTPTPTLQQLPITHIKLEPNLQKTPNNNHRNNNGNILGMNNEKMESSGRKKSGVLKKIKKQKDGIKQEPMDIDQDEIQNNNNTESTSPERLMEHTVDGNNLEVAFEASVTTEEENILPDVGEVNNAEDVGTGNVKLSVKVESTPQRMLAVHSVIAPVDDIPETIIPDAVEYTCEMCSAVFSSRAELLVHVPIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01424531;
90% Identity: iTF_01420417;
80% Identity: -