Mlea020062.1
Basic Information
- Insect
- Megachile leachella
- Gene Symbol
- -
- Assembly
- GCA_963576845.1
- Location
- OY756255.1:9864357-9865484[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 0.003 0.45 12.0 0.1 2 23 49 70 48 70 0.97 2 10 3e-05 0.0045 18.3 0.6 2 23 83 104 82 104 0.95 3 10 5.2e-05 0.0078 17.5 1.1 1 23 110 132 110 132 0.98 4 10 7e-06 0.001 20.3 0.1 1 23 138 160 138 160 0.98 5 10 5.9e-05 0.0089 17.4 0.6 1 23 166 188 166 188 0.97 6 10 5.1e-05 0.0076 17.6 5.4 1 23 199 221 199 221 0.97 7 10 2.2e-07 3.3e-05 25.0 0.2 1 23 230 252 230 252 0.99 8 10 3.6e-06 0.00054 21.2 1.2 1 23 258 280 258 280 0.97 9 10 1.7e-05 0.0025 19.1 5.3 1 23 286 308 286 308 0.98 10 10 0.00034 0.051 15.0 5.9 1 23 314 336 314 336 0.97
Sequence Information
- Coding Sequence
- ATGCTACCTCAGGATGAAGAGCAGGAATGCGGGGCGAACGAGATATTCGGTCAGGAAGAGACAGAAGAGCTGCTCATCACGGATGACAGTTTGCACGTGCCTAAGGTGGAGAACGCAGAGGTGATCATCGCCGACGATATCATTCAATGCCATCTCTGCGGAGACGGTTTCATAACGGAACAAGCTCTCGCTCTGCACCTAAAAATCCACGAAGAGGAGGAGGTTCCCGTCCAAGACGATCATTTAGTTTGCGAGCACTGCGGTTGCAGTTTCGTCACTGCGGCCGAGTTGTCCGACCACCAATTGGAACACGAAACGGACGATGCGTACAGTTGCGAGACGTGTGGTTTCGTCACCGAGCACAGAGAGAGCTTGATCGCTCACCAAAAACGGCACAACATCGACTACAAGTACGAATGCGAGGTCTGCGGTGCCAGCTTCGTCTCGCAGGACACTTACGAAGAGCACCAATCGATGCACACCAACAAAAAACCCTTTCAATGCGACATCTGCAACGCCACGTTCCGTTATCGTCAGGGTCTGAGGCTGCACGCGAAGCTGCACCAACCGGACTACGTGCCGCCCCAAAGGAAGCATCACTGCGAGTTGTGCAACAAGCGTTTCTCCAGGAAACAGGTGTTGCTGGTACACATGAAGACCCACGGAAACGTGGGACCTCAGAAAGAGTACGTCTGTCCCGTCTGCGGCAAGGCCGTGTCCAGCAAGACCTACCTGACCGTACACCTACGCAAACACACCGGCGAAAAACCGCACATCTGCGATCTCTGCGGCAAAGGGTTCATCTCGCAGAATTATCTGAGCGTCCACCGACGCACCCACACAGGCGAGAGACCGCATAAATGCACCCACTGCGAGAAACGGTTCACTCAGCGAACCACTCTAGTGGTGCACCTCAGGGGCCACACCGGCGACCGACCCTATCCCTGCACTTGTTGCCATAAGTCGTTCGCATCGAAAACGATGCTCAACTCGCATCTCAAAACGCACGCCAAGCAGACGGCTCGACAGCAACAggagcaacagcagcaacaacagttgCAACAGGACTCAGAGATACAGGATCAGGAACAATCCCTTGATACGATCACTATATTGTTACCTAGCTAG
- Protein Sequence
- MLPQDEEQECGANEIFGQEETEELLITDDSLHVPKVENAEVIIADDIIQCHLCGDGFITEQALALHLKIHEEEEVPVQDDHLVCEHCGCSFVTAAELSDHQLEHETDDAYSCETCGFVTEHRESLIAHQKRHNIDYKYECEVCGASFVSQDTYEEHQSMHTNKKPFQCDICNATFRYRQGLRLHAKLHQPDYVPPQRKHHCELCNKRFSRKQVLLVHMKTHGNVGPQKEYVCPVCGKAVSSKTYLTVHLRKHTGEKPHICDLCGKGFISQNYLSVHRRTHTGERPHKCTHCEKRFTQRTTLVVHLRGHTGDRPYPCTCCHKSFASKTMLNSHLKTHAKQTARQQQEQQQQQQLQQDSEIQDQEQSLDTITILLPS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00118162;
- 90% Identity
- iTF_00961984;
- 80% Identity
- -