Basic Information

Insect: Megachile lagopoda
Gene Symbol: -
Assembly: GCA_036983795.1
Location: CM072788.1:7349109-7356306[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.00012 0.014 16.4 1.7 1 23 355 378 355 378 0.97

2 8 0.00083 0.096 13.8 2.0 1 23 394 416 394 416 0.97

3 8 1.1e-05 0.0013 19.7 1.0 1 23 439 461 439 461 0.98

4 8 0.0075 0.87 10.7 3.2 1 23 469 491 469 491 0.98

5 8 0.00097 0.11 13.5 0.2 1 23 529 551 529 551 0.97

6 8 6.9e-06 0.00079 20.3 0.8 2 23 557 578 556 578 0.97

7 8 5e-07 5.8e-05 23.9 0.7 1 23 584 606 584 606 0.95

8 8 0.00022 0.026 15.5 1.0 1 23 612 634 612 634 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.00012	0.014	16.4	1.7	1	23	355	378	355	378	0.97
2	8	0.00083	0.096	13.8	2.0	1	23	394	416	394	416	0.97
3	8	1.1e-05	0.0013	19.7	1.0	1	23	439	461	439	461	0.98
4	8	0.0075	0.87	10.7	3.2	1	23	469	491	469	491	0.98
5	8	0.00097	0.11	13.5	0.2	1	23	529	551	529	551	0.97
6	8	6.9e-06	0.00079	20.3	0.8	2	23	557	578	556	578	0.97
7	8	5e-07	5.8e-05	23.9	0.7	1	23	584	606	584	606	0.95
8	8	0.00022	0.026	15.5	1.0	1	23	612	634	612	634	0.98

Sequence Information

Coding Sequence: ATGTCCTCCCTCGATTATCTGGACTTGTGTCGGCTGTGTCTCGTGAAGGACCGTGTTTCGGTGCCGATTTTCGAGGGTGAAGGAGACGTACGgcaaatatttctcaaaatcgCCGCCTGTCTACCGGTCAAGGTTGCAAGAGAAGACAAGTTACCCAAAAAGATATGTGATGATTGCGTGTATAAAGTAGAgctattttatgaattttggaatacaaCAGCGAATGCAGAAAAGCAGCTTCTACAATGGCTAGGAGGAGTCAATTTAGAAGACAAACAGGGTTATGTTACCAATACTCTCAATCAGaatgtaaTGAAACAAGAACAGAGTTCAGAGAACAGGTTAGATGGCAATGTGATGCAGCAAGTTGGCGAGCATCAAAACAATATGGGTATGGGTATGATGGATAATATGGGCCTGGGTATCCCTATGATGATATCCAGTGCTAATCAGCAGCAACAAATAACCTCAGTTCCTATGGACACAAGCGGTAATTCTGTACAACCCGTTCAGGCATTGCCTGGTCCAAGTTCACAAACCACACATAACCAAATATCACAGAATCAATCGAGCTCTGCGCAACAAGAAGATGAGGAAGAAAGTAGCGAAGATGAAGAGAACTCGGATGATGAATGTGATGGAGATGAAGGCCTACCTGTAAAAGAAGAAAGTGAGGAAGATCCCAATAATAGAACTATAGAGCCTACAACTTTTGTAAATGTTTCCTTGGCATGTGACGAAGCTGGTCCTTCTGGGCTACAACAGAAAATCTCAGATATACCTGAGATGCCAATGCCGCAGTCAACAGACGGGGATCCCAAAACTGGGGAAGCAAGCGAGACCTTCGGTGGATTATCGGGGATGCTGCGTCAGATACTTTCGCCATCGCCCGAGACGGGGGACCCCGGTCTGCCCGTCACTTGTACCCTGCTCCAGAACAACTCGATGTTCTCGAATCAGTCATCGATGATGCCCTCGACGTTCCAAACGATCCCGTCCCACTTGCCATCCATCTGTTCCGACCAGGGTCTCATGGACCACGTGCAGTACGTCACCGAGTCCCATCCCTGTTCCACGTGCGGTCTCGAATTCCGAAGCTCCCTGAAACTGAATTACCATATAAGAACCAGTCATCCCACTCTGCCGGAATTCGAGCACAGTATAGAGAACCCGATGAGGTATTCGTGCACCATTTGCTCGCGGAGCTTCTTCGCTCTCAGCCACCTGAGAATGCACGAGGTGACTCACTCGGTGCCGGCCACGTCCTGCGCCTCGGTCCCGACGATATCGACTTCGATCAACGTCGAGAAGACGTTTGTCTGCGATCGTTGCCCGGCCAGTTTCCGGTACCGTACGCTCCTCGAACGACACAGGAGGATGCACGAGGTCGGCCAGGAGAAACCTTACTCCTGTCCTAGGTGTCTGATGCGCTTCGAGACCCGAAATCTGTACAATCATCACGCGAAAACTCACAAGCCCGTGTTAACGGGGAATAATAGAATCGCCGACACCGTTGGCTCCTCCGGTGATCCGGTGACTAGCAGTATTAGCGGCACCCTGGCGACGTCCAAGTCGATTGTCTCGTATCCGTGCGACTCGTGCTCGAAACAATTCGCGACGGTCGAATCTCTGACCACGCATAAGGCTGTGCACAGGTCCAGACCGCTCGTTTGCGACGTCTGCGGCAAAGGTTTCACACATCGCAAGTATTACGTGGTGCATCAACGCATTCACACCGGGGAGAGACCGTATCTTTGTGCCATGTGCGGGAAGTCATTCACTCAGGCCTCTACGCTTACCGTCCATCGGCGATATCACACTGGAGAACGACCTTACACGTGTACCTTGTGTGGTAAAGGATTCGTCACCAGAACCATCATGCTGAATCACATGAAAAAGCATTAG
Protein Sequence: MSSLDYLDLCRLCLVKDRVSVPIFEGEGDVRQIFLKIAACLPVKVAREDKLPKKICDDCVYKVELFYEFWNTTANAEKQLLQWLGGVNLEDKQGYVTNTLNQNVMKQEQSSENRLDGNVMQQVGEHQNNMGMGMMDNMGLGIPMMISSANQQQQITSVPMDTSGNSVQPVQALPGPSSQTTHNQISQNQSSSAQQEDEEESSEDEENSDDECDGDEGLPVKEESEEDPNNRTIEPTTFVNVSLACDEAGPSGLQQKISDIPEMPMPQSTDGDPKTGEASETFGGLSGMLRQILSPSPETGDPGLPVTCTLLQNNSMFSNQSSMMPSTFQTIPSHLPSICSDQGLMDHVQYVTESHPCSTCGLEFRSSLKLNYHIRTSHPTLPEFEHSIENPMRYSCTICSRSFFALSHLRMHEVTHSVPATSCASVPTISTSINVEKTFVCDRCPASFRYRTLLERHRRMHEVGQEKPYSCPRCLMRFETRNLYNHHAKTHKPVLTGNNRIADTVGSSGDPVTSSISGTLATSKSIVSYPCDSCSKQFATVESLTTHKAVHRSRPLVCDVCGKGFTHRKYYVVHQRIHTGERPYLCAMCGKSFTQASTLTVHRRYHTGERPYTCTLCGKGFVTRTIMLNHMKKH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00118215;
90% Identity: iTF_00964667;
80% Identity: -