Mlag005298.2


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Megachile lagopoda
Gene Symbol
-
Assembly
GCA_036983795.1
Location
CM072788.1:10499064-10501726[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.0014 0.16 13.1 5.8 1 23 247 269 247 269 0.97
2 12 0.018 2.1 9.5 6.5 1 23 274 296 274 296 0.97
3 12 0.0012 0.14 13.2 1.4 3 23 307 327 306 327 0.98
4 12 8.7e-06 0.001 20.0 2.2 1 23 420 442 420 442 0.98
5 12 0.0011 0.13 13.3 1.7 1 23 447 471 447 471 0.90
6 12 1.6e-06 0.00018 22.3 0.8 1 23 510 533 510 533 0.95
7 12 6.6e-06 0.00076 20.4 5.1 1 23 566 588 566 588 0.99
8 12 0.00096 0.11 13.6 5.6 1 23 602 624 602 624 0.96
9 12 9.9e-06 0.0011 19.8 1.7 1 23 630 652 630 652 0.98
10 12 0.0014 0.16 13.1 3.2 1 23 658 680 658 680 0.98
11 12 4.7e-05 0.0055 17.7 6.5 1 23 686 708 686 708 0.98
12 12 0.00022 0.025 15.6 0.3 1 21 714 734 714 735 0.93

Sequence Information

Coding Sequence
atggaaattgaaaatacaggAATACCTGTATCAAAAGATAACAACAATATTTGCCGTGTTTGTCTTgcaacaaatgaaattaatcaatGCATTTTCGATGCTAAACGAAATAACTCAAATAATACAAAGATTAGTAATTTGTTAGAGAAACTTCGTTTATGCAGTGGTATTGAGATATTGGAAAATGATGGTTTACCTGCTACCATTTGtatgaaatgtataataagAATTGATAATGCTCATGAATTAAGAAAGCAGTGTCAGCAATCCGATACTCAGTTAAGAAAgttatatggaaaattaaagaaagaatGTGGTACCAATAGATGTAAGCCTACTCAGGACAAATGGTGCCAAACAGATTATCCTTTTTCTTCGGATTCAGTTAAAGTTGAAGGTATAGCTGGGATAGATCATAATCCATCTTCAGACATAAATTTAAGTTGTAATGTTAAACTTATTGGAGAACATAaaggtaataaaataaaccatGTGAAACAtgatgaattaaataattcctttaataaacaaaatattcgtgGTAAATGTATACAAGCAGAATCAGAAAAAAATGTCATTGGAAGAGATGCTTATCGAACAAGAAGAATGACAATGTTTAAAAGAGTAACATCtatagagaatttaaaaaataataaggaaCGACAAAGGCAGTACATAAAAAAGAAGTGGGATACTTCAGAAAGTGATCATTTAATAGATACGCATTCTATGAAGTTACATGTTTGTACAAAGTGTAGTAGACATTATTCCAGCAAAAAATCATTAGATAGACATTTAATAACACATCAGGAAAAAACATTCACATGTAACAAATGTAACAAACACTTTTTTCATTTAGATAAATTAGTAGAACATAGCAAATTACACGAGGTTAAAGAGAAACCTAAACCAGTATTATGTAggatatgtaataaaaattttagaaaaactGATACTATGGTCCGGCatttaaatgttcataaaagaGCTAACCCAAAAGAAGTTCTTTCCATTCTGAAAGAAATCAGGGACAAGAGAAAACTAGATAATACCACTGAGTCTGAAAAAGCAGATGTTGAAGTTAAAAATGGTGATGATAAGAAGGAAGTAGAGAAAGATTTTACAGACAATGATGATACAATTTCAGATAAAGTAGAAACTTGTACATTACAGACTGAACATAGAAATTCTACTTCTTCATTACTATTTTTAGATGTAAATGCTAGTGAAAATGAGTCTTTTGATGATAGTACactttataattgtaaatactgTACTAAACAATATACGACTGAAAAATCACTTGAAAAACATATGCTTATTCAtgctgaaaagaaatttatttgtaacgtgtgcaatatgaaattttaccgTCAAGATCGATTACAAAGTCATAAAAATCGATATGGTCACGATGAGAATAACACATCTCCTGAAATACAAAAACCAGCCGATGAGAAGTCgactattaaattaataaacagcTGGATACGAGAAGAGCTCGACTCGGATAATGAAGGGAAAGGTTTCCCGTGTAAAATTTGTGGGAAATCGTATGATACGAAAAAGTCTTTATCGAAACACCAACTTAATGCACATAATTCAGAAGAAGAAGCCTGTCCATCCTGTGGTGAAATATGTACTTGCGACGAAAAAGATAAAGAACAACAAAATGCAACTGAGGGATCAAAACTGTATCAATGTGCTGAATGCAATAAATGCTTTGAAAATGACCACAAATTGCAAAAGCATATGAGAATTCACGAGCGCCCTAAAGAAGGGCAAgatgtaaatttcaaacgattttTATGCCATATATGTAGTAAAACTTTTAGACACAATACAGGTCTCGTATTTCATATGAGAACGCATACCGGCTACAAACCACacgtttgtaaatattgtgGAAGAGGTTTTGCATCAAATTCAAACCGCATCAACCACGAAAGAACACATACAGGTGACAGACCGTTTGTCTGTCATTTCTGTAGTGCCGCTTTCGCTAAATCGTGCACTCTTAAAGCGCATATTACAACGCATACTGGAGAAGCAAATTATCATTGTAAAACTTGTGGAAAGTCGTTTAGGAGATTGAAATACTTAAAGGAGCATAGATTCACTCATACAGGAGAAAAACCGTATGCTTGCAAAATCTGCGGAACGGCGTACAGTCATTCCGGAAGTTTATTCGTACACGAGAAAAAATGTAAAGCACAGTATAATAGTTATCAGTCTAACTCGACACAAAATACAGAATCGTATTGTCAATCTGAGACAACTTCATCGAACGTAACTCCgatcattacaattttaccCCAAGTCCAGTTGAATGTTTCTGATACGTTAAATACGCAAAATAGCAAAAGCTATGTAGATAATCAGATAATAAACTCCCaggatattaataatttgaatactgTCAGTTCGTCGGATCTGCATGTTCATTCGAATTCGGATATTCCTGATGTTTCTTTGACCATTAAAAGTTTCGCCCTGATCAGGCAAATGTTTCAATCGTAA
Protein Sequence
MEIENTGIPVSKDNNNICRVCLATNEINQCIFDAKRNNSNNTKISNLLEKLRLCSGIEILENDGLPATICMKCIIRIDNAHELRKQCQQSDTQLRKLYGKLKKECGTNRCKPTQDKWCQTDYPFSSDSVKVEGIAGIDHNPSSDINLSCNVKLIGEHKGNKINHVKHDELNNSFNKQNIRGKCIQAESEKNVIGRDAYRTRRMTMFKRVTSIENLKNNKERQRQYIKKKWDTSESDHLIDTHSMKLHVCTKCSRHYSSKKSLDRHLITHQEKTFTCNKCNKHFFHLDKLVEHSKLHEVKEKPKPVLCRICNKNFRKTDTMVRHLNVHKRANPKEVLSILKEIRDKRKLDNTTESEKADVEVKNGDDKKEVEKDFTDNDDTISDKVETCTLQTEHRNSTSSLLFLDVNASENESFDDSTLYNCKYCTKQYTTEKSLEKHMLIHAEKKFICNVCNMKFYRQDRLQSHKNRYGHDENNTSPEIQKPADEKSTIKLINSWIREELDSDNEGKGFPCKICGKSYDTKKSLSKHQLNAHNSEEEACPSCGEICTCDEKDKEQQNATEGSKLYQCAECNKCFENDHKLQKHMRIHERPKEGQDVNFKRFLCHICSKTFRHNTGLVFHMRTHTGYKPHVCKYCGRGFASNSNRINHERTHTGDRPFVCHFCSAAFAKSCTLKAHITTHTGEANYHCKTCGKSFRRLKYLKEHRFTHTGEKPYACKICGTAYSHSGSLFVHEKKCKAQYNSYQSNSTQNTESYCQSETTSSNVTPIITILPQVQLNVSDTLNTQNSKSYVDNQIINSQDINNLNTVSSSDLHVHSNSDIPDVSLTIKSFALIRQMFQS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00962682;
90% Identity
iTF_00962682;
80% Identity
-