Basic Information

Insect: Megachile lagopoda
Gene Symbol: ttk
Assembly: GCA_036983795.1
Location: CM072794.1:451107-463811[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 2.3e-07 2.7e-05 24.9 1.9 1 23 610 632 610 632 0.98

2 8 2.9e-05 0.0033 18.4 2.0 1 23 638 660 638 660 0.98

3 8 1.8e-06 0.00021 22.1 0.3 2 23 669 690 669 690 0.98

4 8 1.8e-05 0.0021 19.0 0.2 3 23 698 718 696 718 0.97

5 8 1.9e-07 2.2e-05 25.2 3.0 1 23 724 746 724 746 0.98

6 8 3.2e-06 0.00037 21.3 0.7 1 23 752 774 752 774 0.98

7 8 6.8e-05 0.0079 17.2 7.5 1 23 780 802 780 802 0.98

8 8 0.00076 0.088 13.9 1.0 1 21 808 828 808 829 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	2.3e-07	2.7e-05	24.9	1.9	1	23	610	632	610	632	0.98
2	8	2.9e-05	0.0033	18.4	2.0	1	23	638	660	638	660	0.98
3	8	1.8e-06	0.00021	22.1	0.3	2	23	669	690	669	690	0.98
4	8	1.8e-05	0.0021	19.0	0.2	3	23	698	718	696	718	0.97
5	8	1.9e-07	2.2e-05	25.2	3.0	1	23	724	746	724	746	0.98
6	8	3.2e-06	0.00037	21.3	0.7	1	23	752	774	752	774	0.98
7	8	6.8e-05	0.0079	17.2	7.5	1	23	780	802	780	802	0.98
8	8	0.00076	0.088	13.9	1.0	1	21	808	828	808	829	0.94

Sequence Information

Coding Sequence: ATGATGGGAGAAGTGATTCGCGTAGCTGGAAAGACACCGGACGTTGGGGAATTCCTTAAGGAGGCGATGCTGTCCCAAAGATTCGCCGACGTTGCTCTCTGTTGTCCGGGTGGCCAAAGATTCTTGGCTCATCGTTTGGTTCTTTCAGCTGCCAGCCCTTATTTGCAAGAAGTGTTGTTGGCTCACAGCAGAACGTCGTCGCACTGCGAGCCGATCACGGTGATTTTAGCCGAGGTGGAGGCGCCAGAACTGGCGGCCATCCTTGGTTTCGTGTACACCGGAAGCGCGACGGTACCTCGTCTTCGGTTGAACGCTTTTCTACGGGCTGCCGAGGCTCTCCGCATCAGACTGCCTCCTGTACCGGTCGTGATGACTTGCTCGCAAGCGGACTGTAAACAAGAAGACATCAAAGACGTGAAGATCAACCCGAAGTACCTGCGCTGCGATCAATATCCATGCTGCGACGGCTGGTACCGTCCTGGGAGAAATCAAGATGGAGATTCTACGAGCAAAGAGGAACCGTATCCACCGATCGAGTCCTTGGAAACCGCAAGAGAAATCAGACCGCTTCCTGAATCGATGAACTTCGTTGAATCGAGATACGGAGTTGGAAAATATTGCTCCAGCACGTTCTGGTCCGTTCCACCGCCGCCATTTTCGAATCTCGAACACGAGAAGAACGTCGAACGTTTAGAGAAACGCGAAACGAATCGAACCGTGGTACCTGTCATCGATGGGATCAACTCGACGCCCGGTGGACGTACGGAAAACCTTCGAGTCTGTGATTCGTCTATCGAACATCGTCAACGGGAACTCTGTTTCTCGAGAAGCTTCTACGATAGACAATTAGAACCGTTCGAATCGAGGACGAAGACTGATCAGAATCCTGGAAAAGATTTCGCGATGTACGATCGTTGCTTGGAGCAAGAGAGGGCTCCTGTGATTCGTTCCCGAGTCGAACGTTGTCAGGACGGGAACACCGTTTCACCCGATCGGATCAGATTCTTCGAAAAGTCGGATCACGGCGAAGATTTGTCGTGTCAGGAAGGTTGTTTGCTTTGGAAATCACCCAGGAGACACGTGGCCAACCGTGTCACTGCATCGCCATGGAAACAGACCGTCAGACCTTACCACTTGCCCAAGTTACAGCCTATCGTTCTTCAACCTGGACTTCCTCTTCGATGCGCCGACGATGCTAATGAAGTCGGTGAAAAACTTGGTCCAACGGAAACGACGCGAGTAACCTCTGGCAGTTTGAATCTACGGTTACCGAGAAATGCAGCATCTAACGATCTCTACTACGACCTCGAAGTTCCTATCGTCCACGAAACCGTgtacagtaataataataccCGAACATTGGAAGATAATAGTTCGGGAACGAAACAACAGGAGTTTTATTCGGGCGAAATCCCGATGTCGTCCAGCGCTCGAATCGCTTCGTCGATCGGTAACGAGGTCAGAAACAACGAATCTCTTTTGCAGCTTGAAAACAACGCGACATCGACCGCGACGAGGTGTACGTCGAGCGTTAACGAGAACCGCGAATCGAACCATAATCGAAAGACTAGTTATTTCGGATCAGTGTCACAGCATCCGGTCCAGAAGCCGGAAATTTCTCATCCCGTTAGCAGATTGTGCGACACGATCGACTCGAACGATACGAACGATCGTTTCGCGACAACGGAAACGGGAAAAGAGGCGCGCATCGACGACGATAAGGTCGCCGAGCGAGTGATCAGAAACAGCGACAACAATAACAACGACGCGATCATTGGTAACGATATTTCTCAGCACGGTGGTAGACCCGTTACGATTCAGGAAAATCATCGATGCGACCAGTGTGGCAAGACTTTCGTCACCAGAGCATCCTTGAAGGTACACGTCAGAACGCACTCGGGAGAGAAGCCGTTTCGTTGCGCCGATTGTGGCAAGCAATTTTCTCAGCTGCGAAACTACAAGTATCATAGGAGCGTTCACGAGGGTACCAGAGAATTCGCGGCCACCTGTCCAGAATGCGGTAAATACTTCAACGATCGTGGCTACCTGAGCTCTCACATGAAGATCCATCGTAATCGGAAAGAATACGGATGCACCGAATGCGGGAAAAGCTTCAATCAACGGGTCGCTTACAATATGCACGTGAGGATACATACCGGCGTGAAACCGCATCAATGCGAGCAGTGTGGCAAAGCTTTCTCCAGAAAGATGCTGTTGAAACAGCATTTGAGGACCCACTCGGGTGAAAGACCGTATCAGTGTCAAGTCTGCCAGAAGGCTTTCGCTGATCGCTCGAACATGACGTTGCACACGAGGCTTCATTCCGGATTGAAACCGTATCAATGTACCCTGTGTTCGAAAGCGTTCACGAAGAAGCATCATCTCAAGACTCATCTCAACTACCACACCGGCACCAAGCCGTACTCTTGTCCAAATTGTGCTCTACGATTTTCGCAGAGCAGCAATATGAGAACCCATTTCAAAAAGTGTACCGTTAACAATTCCGTCGAAACGATGAGCACACGAATGGAGAGCAATATCGTGGAATCGTCCAAGGATGCGCAGGTAAGGATAATATCGAGGACACCTACGGATACTTTGACACCGCCGAATTCGGATCAAGAATTAAGTATTTTAACGCCTATTTCCAAGATCACCGGAATCGATGTAACCGGGACGTAG
Protein Sequence: MMGEVIRVAGKTPDVGEFLKEAMLSQRFADVALCCPGGQRFLAHRLVLSAASPYLQEVLLAHSRTSSHCEPITVILAEVEAPELAAILGFVYTGSATVPRLRLNAFLRAAEALRIRLPPVPVVMTCSQADCKQEDIKDVKINPKYLRCDQYPCCDGWYRPGRNQDGDSTSKEEPYPPIESLETAREIRPLPESMNFVESRYGVGKYCSSTFWSVPPPPFSNLEHEKNVERLEKRETNRTVVPVIDGINSTPGGRTENLRVCDSSIEHRQRELCFSRSFYDRQLEPFESRTKTDQNPGKDFAMYDRCLEQERAPVIRSRVERCQDGNTVSPDRIRFFEKSDHGEDLSCQEGCLLWKSPRRHVANRVTASPWKQTVRPYHLPKLQPIVLQPGLPLRCADDANEVGEKLGPTETTRVTSGSLNLRLPRNAASNDLYYDLEVPIVHETVYSNNNTRTLEDNSSGTKQQEFYSGEIPMSSSARIASSIGNEVRNNESLLQLENNATSTATRCTSSVNENRESNHNRKTSYFGSVSQHPVQKPEISHPVSRLCDTIDSNDTNDRFATTETGKEARIDDDKVAERVIRNSDNNNNDAIIGNDISQHGGRPVTIQENHRCDQCGKTFVTRASLKVHVRTHSGEKPFRCADCGKQFSQLRNYKYHRSVHEGTREFAATCPECGKYFNDRGYLSSHMKIHRNRKEYGCTECGKSFNQRVAYNMHVRIHTGVKPHQCEQCGKAFSRKMLLKQHLRTHSGERPYQCQVCQKAFADRSNMTLHTRLHSGLKPYQCTLCSKAFTKKHHLKTHLNYHTGTKPYSCPNCALRFSQSSNMRTHFKKCTVNNSVETMSTRMESNIVESSKDAQVRIISRTPTDTLTPPNSDQELSILTPISKITGIDVTGT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00963996;
90% Identity: iTF_00963996;
80% Identity: iTF_00961943;