Basic Information

Insect: Megachile lagopoda
Gene Symbol: -
Assembly: GCA_036983795.1
Location: CM072800.1:18760727-18763049[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 1e-05 0.0012 19.7 4.8 1 23 292 314 292 314 0.97

2 12 6.2e-05 0.0071 17.3 3.9 1 23 318 340 318 340 0.98

3 12 0.00051 0.059 14.4 3.1 3 23 347 367 345 367 0.96

4 12 0.00025 0.029 15.4 3.5 1 23 419 441 419 441 0.98

5 12 0.0008 0.092 13.8 1.4 1 23 446 468 446 468 0.97

6 12 6.7e-05 0.0078 17.2 2.6 1 23 517 539 517 539 0.99

7 12 5.9e-05 0.0069 17.4 0.5 2 23 547 568 546 568 0.97

8 12 9.9e-07 0.00011 22.9 2.1 1 23 578 600 578 600 0.96

9 12 0.00023 0.026 15.5 1.6 1 23 606 628 606 628 0.97

10 12 0.00016 0.019 16.0 0.7 1 23 634 656 634 656 0.98

11 12 4.8e-06 0.00055 20.8 2.0 1 23 662 684 662 684 0.96

12 12 8.5e-05 0.0099 16.9 0.3 1 22 690 711 690 711 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	1e-05	0.0012	19.7	4.8	1	23	292	314	292	314	0.97
2	12	6.2e-05	0.0071	17.3	3.9	1	23	318	340	318	340	0.98
3	12	0.00051	0.059	14.4	3.1	3	23	347	367	345	367	0.96
4	12	0.00025	0.029	15.4	3.5	1	23	419	441	419	441	0.98
5	12	0.0008	0.092	13.8	1.4	1	23	446	468	446	468	0.97
6	12	6.7e-05	0.0078	17.2	2.6	1	23	517	539	517	539	0.99
7	12	5.9e-05	0.0069	17.4	0.5	2	23	547	568	546	568	0.97
8	12	9.9e-07	0.00011	22.9	2.1	1	23	578	600	578	600	0.96
9	12	0.00023	0.026	15.5	1.6	1	23	606	628	606	628	0.97
10	12	0.00016	0.019	16.0	0.7	1	23	634	656	634	656	0.98
11	12	4.8e-06	0.00055	20.8	2.0	1	23	662	684	662	684	0.96
12	12	8.5e-05	0.0099	16.9	0.3	1	22	690	711	690	711	0.96

Sequence Information

Coding Sequence: ATGACGGAATACTTTGATTTACCGCTTAATATGGACAGAATATGCAGAATTTGCCTTACAGAGGGTACGAATTTATCTTCTATTTTTTGTACCGATCAAGAAGTAAATGATTTTTCTGATCTTCCACAAAAAATACAAGTTTGTGGGTCAGTAGAAATTCATGAACAAGATGGATTACCTTCATTAATTTgtgatatttgtatttataaagcAAGCGTTGCTCATGAATTTAGGCAACAATGTCAGCATTCTGATGCCAAATTAcgaatgtattataataaaccagcaaaaattactattgtggatACATGCACACAAACAGAACCAGAGATAAGAACAGCATTATCAAAAGAGCAAGTTAGCGAAGAAGATTATTTTGTAAAGGAGGAAATGCAAGGAGcatcatcaaattctcaagaatttatacaaaataacaattcaTATTGTAGAAGTGAATCTGGTTTAAATACTGGCCAAATTGAGATGCAGAATGAAAAACTTTTTATATGTTCTATTGGATTTGAAACAACTAAGGAATCTCAGAAGGAAGCTTGCAGTTCAGAAAATGATATACATCAAACTTCTCTTATAGAAGAAGGTACTAATGATGTTTCTGAAACTAtagatgtacaaaataaatctgAAGAAATTCCAGACACTAGTCAAAATATGGAAGAAGATGACAAAAAACAAGAGGATGAATTTcttgatgaaaatttattaaatgatgaTATCAAAGAGGAAGAAGTTTTACAGAAACGTACATCAGGTAGAAAAGTTAAGTCAGTGCCTAATAAAACTTACAGTGAAGACGAGATCGatgataattattatgatttaaGTAATGATGGTCAAGATTCTGGAGActcgaaatttaaatgtaaaatatgttcaaaatGTTTTAGTACACAGAGAGGTTTGAAAAAACATTCTCTTGTTCATGAAAAAAAgcataaatgtaatatttgttcaaaaatgttCTACAAACAGGAGAATATGGAAAATCATAGAAAGATACATGCATCCAAACCTCTTGCATGTCAGTTATGTCATGCATGTTTTTCTAAGCCTCAAAGTCTTGTACGCCATTTAAAATCCCATACAGAAAAAGTAAATGACatgattaaacaaattaatacagATGAACAGAAGGATAATAATGAACcgaagaaagaaatgaaacttGAAGACGATACAGATGATGAAAGTGGTACTGTGAATGAAggttataattttgaaaatgcacCTGAATTGtacaaatgtgaaatttgtagTCAGTATTGTTCttctttaaaaaatctaaaaagaCATACTCTGGTACATggtgataaaaaatattcgtgCACTGTATGTAAAAAATGGTTCTTTAGGCCAGATACTTTAAAAAAACATGCAGAAAAACATGGACATGGATTATTAGACAATTTagttgataataataaattctttgatTCTGATGATGACTCTTGTCCAAATACTGCAAAAAGTACTGAGCAAGAGAGTGAAAGTgttaaaaaggaagaaagtgATGAAGATGGTTCTGGTGAATATAAATGCCAACATTGTGATAAAGTCATGGCTACGAAAAAAGGTCTTAGACGCCACGTATCTACACATAAGCCGAAAGCTGAACCAGTtacttgtgaaatttgtggaaaGATTTGTGCTAGTCAAGCTCGTCTTGTACTTCATCAAAGGACACATGTACCAAAAGAAAAAGTTCCACGAGAATACTTGTGCCACATATGTAGTAAAGTGTATCCAAGTAACTCTTCCCTAACATATCATATGAGAACTCATACTGGTATTAAGCCACATGTTTGTAAAACTTGCAATAGTGGATTTACTACAACAACCAGTTTAGCAAATCATATTAGAATTCATACTGGTGACAAACCATTTGTTTGTCATGTATGTAGTGCTGCATTCGCTGTAAGTTCTGCTTTTAGACGACATTTAACTCGTCATACTGGAGAAGCAAACTATTTGTGTAAAACATGTGGTAAAGCATTTAAAAGACTAAGTACTTTAAAAGAACATACTTACACTCATTCTGGTGAAAAACCATATGTATGTAAAACATGTGGAGCAGCATATAGTCATAGTGGTAGCTTATTTGCTCATCAAAAACGTTGTCGAGCTCAGTATGGAGAGATAGTTGTAGAGGAGCACCATCATTCAGTTGCTCATCATATTCATGTAAATAATGTGCAATCTGCAGTACGATCACTTGCTGTGATAGgacaaatgttttaa
Protein Sequence: MTEYFDLPLNMDRICRICLTEGTNLSSIFCTDQEVNDFSDLPQKIQVCGSVEIHEQDGLPSLICDICIYKASVAHEFRQQCQHSDAKLRMYYNKPAKITIVDTCTQTEPEIRTALSKEQVSEEDYFVKEEMQGASSNSQEFIQNNNSYCRSESGLNTGQIEMQNEKLFICSIGFETTKESQKEACSSENDIHQTSLIEEGTNDVSETIDVQNKSEEIPDTSQNMEEDDKKQEDEFLDENLLNDDIKEEEVLQKRTSGRKVKSVPNKTYSEDEIDDNYYDLSNDGQDSGDSKFKCKICSKCFSTQRGLKKHSLVHEKKHKCNICSKMFYKQENMENHRKIHASKPLACQLCHACFSKPQSLVRHLKSHTEKVNDMIKQINTDEQKDNNEPKKEMKLEDDTDDESGTVNEGYNFENAPELYKCEICSQYCSSLKNLKRHTLVHGDKKYSCTVCKKWFFRPDTLKKHAEKHGHGLLDNLVDNNKFFDSDDDSCPNTAKSTEQESESVKKEESDEDGSGEYKCQHCDKVMATKKGLRRHVSTHKPKAEPVTCEICGKICASQARLVLHQRTHVPKEKVPREYLCHICSKVYPSNSSLTYHMRTHTGIKPHVCKTCNSGFTTTTSLANHIRIHTGDKPFVCHVCSAAFAVSSAFRRHLTRHTGEANYLCKTCGKAFKRLSTLKEHTYTHSGEKPYVCKTCGAAYSHSGSLFAHQKRCRAQYGEIVVEEHHHSVAHHIHVNNVQSAVRSLAVIGQMF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00962662;
90% Identity: iTF_01123204;
80% Identity: -