Basic Information

Insect: Megachile lagopoda
Gene Symbol: -
Assembly: GCA_036983795.1
Location: CM072798.1:1426565-1432073[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.19 22 6.4 1.4 1 23 302 324 302 324 0.91

2 12 5.3e-06 0.00061 20.7 3.2 1 23 329 352 329 353 0.97

3 12 0.0028 0.32 12.1 0.9 1 23 409 432 409 432 0.97

4 12 1.6e-07 1.9e-05 25.4 0.5 1 23 438 460 438 460 0.98

5 12 0.0088 1 10.5 0.1 1 23 469 492 469 492 0.89

6 12 2.4e-07 2.8e-05 24.9 3.6 1 23 498 520 498 520 0.98

7 12 4.9e-06 0.00057 20.8 1.0 1 23 526 548 526 548 0.98

8 12 3.3e-05 0.0038 18.2 2.0 1 23 554 576 554 576 0.97

9 12 1.4e-08 1.6e-06 28.8 1.8 1 23 582 604 582 604 0.99

10 12 1.1e-05 0.0013 19.6 5.7 1 23 610 632 610 632 0.98

11 12 1.1e-05 0.0013 19.6 1.6 1 23 666 688 666 688 0.98

12 12 2.1e-07 2.5e-05 25.1 2.4 1 23 694 716 694 716 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.19	22	6.4	1.4	1	23	302	324	302	324	0.91
2	12	5.3e-06	0.00061	20.7	3.2	1	23	329	352	329	353	0.97
3	12	0.0028	0.32	12.1	0.9	1	23	409	432	409	432	0.97
4	12	1.6e-07	1.9e-05	25.4	0.5	1	23	438	460	438	460	0.98
5	12	0.0088	1	10.5	0.1	1	23	469	492	469	492	0.89
6	12	2.4e-07	2.8e-05	24.9	3.6	1	23	498	520	498	520	0.98
7	12	4.9e-06	0.00057	20.8	1.0	1	23	526	548	526	548	0.98
8	12	3.3e-05	0.0038	18.2	2.0	1	23	554	576	554	576	0.97
9	12	1.4e-08	1.6e-06	28.8	1.8	1	23	582	604	582	604	0.99
10	12	1.1e-05	0.0013	19.6	5.7	1	23	610	632	610	632	0.98
11	12	1.1e-05	0.0013	19.6	1.6	1	23	666	688	666	688	0.98
12	12	2.1e-07	2.5e-05	25.1	2.4	1	23	694	716	694	716	0.98

Sequence Information

Coding Sequence: ATGGCAGAAGTACGCCTATATGATTCAACAATTTGTCGATTATGTGCTGAAGATAACGGAAATGGAGAATTACTTTACATGGGGGACGGTGATGATCCAGATTTGAGTTCCATGGTCAATCGGTACTTGCCACTCAAGattCGAGATGATGGGAAGTTACCACGTACTATATGCCCTGGTTGCAACATACAACTCGAGGCAACAATACAGTTCTTCGAGTTACTGGTGGATGGTCAAAGAAAAATTCGTGAGATGTGGAAGCATCAAGTAGAACAGCAACGTAAAGCTGAACGAGAACGACTTCGTGCAGAGAAAGAAACAGATGTCATGGGAGAAACATCAGAATTAGATTATGTTTCACGATCGAATGATGAAGATCAATTTGaacaacaaattataataaaaaTAATGCCAGATGGTTCTATGTATGCAGCAGAACATGAAATGAGTTTGCAAATGGAGGGATTAAATAAACCAAAACGAAAAAGAGGACGTCCACCAAAATCACATACAGAAAATATGTCTGTGgaattgtCAAAAGGAGAAGTAATAGAAGGAATTAgtcaagaagaagaagataaaCAGGAAGAAGAAATGGATGAAATTGATGGAGATGGTAGACGTCGCAGGAAACGTAAGGTCCCCAAAAgATATATGGAGGCAGTTCAAGGCAAAGAATTAGAAAGAATATATAAAGAAGAAGGAGTAATTGACGAAGAAGATGATGATGAACCTGATACTTTTGAAGATTCTGAAGAGCAGTTGAATATTTCTGTTCCTGATAGTCAAGAAGaaataattggGCATTTAGAATCTGAAGAAGGAAAGGATCTAGGAGAATTGGTGATAGTAAATCGAGGTAGAGGGCGGGGTCGACCGAAATTACGtcgtagaaaaaataaatttacatgtcAGTTATGTGGCCGGGGATTTTTACAGCGCAGCAGATATATCGTAcacaagaGTTTTCATAAAGGAATAAGATATGAGTGCTCAGAATGTAAAAAACTATTTACAAAtaaggaaaatttagaattgcaTCAAAAAACAACACATCACACTGGAAACGGtgtatatcaaaatttagaacataTTCAAGAATCAGATGTCGAATCGAAACGTCAACTTCCTGAAGAAGATCAAGTTTCTAATGTACTGGAACATACTTTGTCGGAAGAACAGGATATGAGcaagttttcaaacaattCTGATTCTCAGAAAAGTTTTTCGTGCGAacaatgtgataaattatttgaaacaaagcAGACTTAtgatttacatttgaaaatggcACACGaacgtgataaattatttgtttgtaCCATTTGTAGTAAGAGTTTCTCTCAACAAACAGCTTTAAAAGCTCATATGTCCATACACGagAagcagaaattagaaaaagaatatCCTTGTGACATTTGTGGAAAAATACTTAATCATCCAAGTTCCGTGGTATATCATAAAGAAGCAGAGCACAATAATGGACGACGATTTGTTTGTAACAAATGTGGAAAGAGTTTTAAACACAAACAGTTGTTACAACGTCATCAGCTTGTACACTCAGACGATCGACCATACATCTGTAAATCTTGCAATGCTAGTTTCAAAACAaaagcaaatttaattaaccatCAGTCGACACATACAGGCGAAAAGAAATACTTCTGTGAAATTTGTGGACAACAGTTTGCACATAAAACTAGTCTTACACTTCATTACAGGTGGCATACGGGTCATAAACCATATACATGTGAGGTATGCCATAAGAGTTTTTcacaaaatggaaatttgcaagAGCATATGCGGATACATACAGGAGAGAAACCTTATTGTTGTGATTATTGTGGAAGAAAATTTACTACCTCTTCACAATTCAAACTTCACGTTAAGCGACATACTGGCGAACGTCCTTGGAAATGTGAATTCTGCGCAAAATGTTTCTTGCATAAAGATACATGGAAATGTCACGTGCGTAGACATAAAGGAGAACGTCCCTTTCAATGTGCTCATTGTAATCGTGGTTTTACAGAACAATGGGCTTTAAAGAAACATCTTCGTCTGCACACAGGTGAAAAACCTTACTCTTGTGATGTTTGTGGAAAAACATTTGCAGATTGTTCGAATTtaacaaaacataaaaaaGTCCACAGAGAGACAAAAGTTTCTGCAATAGGTGAAATAGAAGGATCTCCAATTGGTGAAGTTTGGCAGATTTTACCAAGTTCTCAGGAATCTGATGAACATTCTTTAACTGATCAAATGGCCCAAGTCATTACAACCGATGATACATCTGGAGATGGTattcaacaaattatttatgtttcgtATCAAGATCCAGATGATCCTAATCAATCCCGGACGTTACATTTCGTTGATGCTGGAATAATGAGAAACAAGGAAGAgaaaacaaatacaaatgaaGCATTATCACATTTAAATGTTGagaataatgaaatactttCTGATTCCCCTCATCCTAatggtaataataattcaactgACCGAATAAACGTTGAACTGTCAGAATCAGACCTTCAGCTTCAGattaCAGATGAAGAAGGTAATCCAATTCCTCTTTCGATTCAAGATGCTCGACAGCTTTTATCTCAGAGTCAGTTTGTTAATCAACTTAACGATGGGCAAGAAATTCGAATTCATCCCGGAACAATTCCTGATGACTTAGCAACGCCATTAGGAATGCATGTTAATCAGAACTCCGATGCGAAAGATGTTGACATCTCTAATGCGATTGAAccaaaagtgaaaaatatttcaactatACAAACAGATGCAGAAGCAATTGTAAAGACATTGGAgGATGAAGATACGGATGCAAATGCGGTCGCAACTATCAATCAGATGGAAGAATCTGAACAACCAGGGATCACCGAGAATGAACAAGCAATTGAATTTACAACACAGGATGGTCAGAAAGTTCGTTTAGTTGCTTCTTATCACGTTGATCCAATGCACCTTGCTTCCGAGTACCTGactattgtataa
Protein Sequence: MAEVRLYDSTICRLCAEDNGNGELLYMGDGDDPDLSSMVNRYLPLKIRDDGKLPRTICPGCNIQLEATIQFFELLVDGQRKIREMWKHQVEQQRKAERERLRAEKETDVMGETSELDYVSRSNDEDQFEQQIIIKIMPDGSMYAAEHEMSLQMEGLNKPKRKRGRPPKSHTENMSVELSKGEVIEGISQEEEDKQEEEMDEIDGDGRRRRKRKVPKRYMEAVQGKELERIYKEEGVIDEEDDDEPDTFEDSEEQLNISVPDSQEEIIGHLESEEGKDLGELVIVNRGRGRGRPKLRRRKNKFTCQLCGRGFLQRSRYIVHKSFHKGIRYECSECKKLFTNKENLELHQKTTHHTGNGVYQNLEHIQESDVESKRQLPEEDQVSNVLEHTLSEEQDMSKFSNNSDSQKSFSCEQCDKLFETKQTYDLHLKMAHERDKLFVCTICSKSFSQQTALKAHMSIHEKQKLEKEYPCDICGKILNHPSSVVYHKEAEHNNGRRFVCNKCGKSFKHKQLLQRHQLVHSDDRPYICKSCNASFKTKANLINHQSTHTGEKKYFCEICGQQFAHKTSLTLHYRWHTGHKPYTCEVCHKSFSQNGNLQEHMRIHTGEKPYCCDYCGRKFTTSSQFKLHVKRHTGERPWKCEFCAKCFLHKDTWKCHVRRHKGERPFQCAHCNRGFTEQWALKKHLRLHTGEKPYSCDVCGKTFADCSNLTKHKKVHRETKVSAIGEIEGSPIGEVWQILPSSQESDEHSLTDQMAQVITTDDTSGDGIQQIIYVSYQDPDDPNQSRTLHFVDAGIMRNKEEKTNTNEALSHLNVENNEILSDSPHPNGNNNSTDRINVELSESDLQLQITDEEGNPIPLSIQDARQLLSQSQFVNQLNDGQEIRIHPGTIPDDLATPLGMHVNQNSDAKDVDISNAIEPKVKNISTIQTDAEAIVKTLEDEDTDANAVATINQMEESEQPGITENEQAIEFTTQDGQKVRLVASYHVDPMHLASEYLTIV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00361071;
90% Identity: iTF_00963342;
80% Identity: -