Mfla012675.1
Basic Information
- Insect
- Mecyna flavalis
- Gene Symbol
- -
- Assembly
- GCA_949319885.1
- Location
- OX439422.1:5366909-5379713[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 15 0.0053 0.46 11.9 0.1 1 23 236 258 236 258 0.93 2 15 2.2 2e+02 3.7 0.1 3 23 281 302 279 302 0.90 3 15 0.03 2.7 9.5 0.7 3 23 324 344 322 344 0.92 4 15 0.0055 0.49 11.9 2.7 1 23 348 371 348 371 0.91 5 15 0.00014 0.012 16.9 0.9 1 20 377 396 377 397 0.96 6 15 4.7 4.2e+02 2.6 0.4 1 23 406 429 406 429 0.93 7 15 3.4e-05 0.003 18.8 0.7 1 23 435 458 435 458 0.96 8 15 0.05 4.4 8.9 6.1 1 23 464 487 464 487 0.96 9 15 0.05 4.4 8.9 6.1 1 23 495 518 495 518 0.96 10 15 0.05 4.4 8.9 6.1 1 23 526 549 526 549 0.96 11 15 0.05 4.4 8.9 6.1 1 23 557 580 557 580 0.96 12 15 0.053 4.7 8.8 6.6 1 23 588 611 588 611 0.96 13 15 0.029 2.6 9.6 3.2 1 21 619 639 619 640 0.94 14 15 0.05 4.4 8.9 6.1 1 23 650 673 650 673 0.96 15 15 0.16 14 7.2 0.3 1 16 681 696 681 698 0.89
Sequence Information
- Coding Sequence
- ATGAGCGCAAATAATTCAAAGAAAGGACTTGTTTACGATCCGGGGACTTGCCGGTGCTGTGGAGCTAGTAAGAAATGCCGGCTTCTGAATATGGAGTACGAACATCAGAAAAAGAAAGAGATATACTCAGATATGTTTGTGGAATGTTTTGGCTTAGTGCTATCACATCTAGACGGGGAGCCATCAGACCGCCTCATATGTGCCATGTGTGTAGGTCGCCTGCGGGAGGCGTGCTCCTTCCGACGACAAGTCTTGGAGTGTGAGGAGAGGCTGCTGCAGGCCAGAATACATGTGCATGATGCCCCAATGGAAATCAAAACAGAAATCATCAAAGAAGAAGTCTCTGATGATGCGATAAACTGTGATGACGGGAATCATGAAGATGTAATGGAAATCATTGatacaGCAAATGATACTATGGAGGTGCCTAAAGATAAATGCACAGAAGAATTAAGTAGTAATAAGAGTATTGAGAAGAAAAATGAAGACAGGCTTCAGAAAGAACTACTGCTCAAAATACAAGGAATGAAGAAACGACTCAAGATGATACAAAGTGCCAAACGCAAGACAGAAAAACCCAAAAAACAGCCATTACCATCACCACCTGTAGAAAAGTTCGTCGACGAGGAATCCATAGCTTTCCAGAACATGCTGATTCTTATTGAGAACTCTTACGTCTACCCATTTCAGACAGCATACAGTTCGTTCCACTGCGCGTACTGCGGCGCCATGTTCCCGTCGCCCGCGCCGCTGCGCGCGCACTCGCTCGGTCACGACCCGCGGAAGTACCGTCACGTGGCCGCCGCAAGACCGACGTACTTGGACGTCCGCCGGACGGACTGCCGGCTGTGCGACGAGCGGCCGGAGGACGTCCGGGAGTTGCAGAGGCATCTTGCGACTGCGCATCGATTGCCTATACGCAGAAAGATCAACGCGCTCATGTTTCGCCTAACCGACGGGGCTCTCTCTTGCATAGAGTGCGATGTAAGCTTCATGTTCTTTCACGCATTAAAGAGACATATGGCGGTGCACTTCGGCAACTTCGTATGTGATGTGTGTGGCGAACATTACTTCGACAAGAGCGCTTTGGAGCAACACTGCAGGAACACTCATAGGAGCGATGTGAAGTTCACTTGTCATGAGTGCGGGAAGCTATTTAAGAGACAGCAAGCCCTCAGTATGCACCTATCGTGTGTGCATAAGAAGGAACCTGCATTTCAGTGCATCAAGTGCGAAGTGTCGCTATACTCCGCTCAAGAGAGGTACAAGCATATGCGAGATGCGCATGGCGTCGGCCGCACACACGCATGCGAAAAATGCGGGAAAGCATACAACAGCCGCGGAAATCTGCTCGAGCACAACCGAACTGTGCACTTACGAGTGTACAAGCACAAGTGCGCACTGTGCCACAGGGGCTTCTCGCACCCGCACCGGCTGTCCGAGCACGTCATGTCCATGCACAGGTCAGTGCGAGTGTACAAGCACAAGTGCGCACTGTGCCACAGGGGCTTCTCGCACCCGCACCGGCTGTCCGAGCACGTCATGTCCATGCACAGGTCAGTGCGAGTGTACAAGCACAAGTGCGCACTGTGCCACAGGGGCTTCTCGCACCCGCACCGGCTGTCCGAGCACGTCATGTCCATGCACAGGTCAGTGCGAGTGTACAAGCACAAGTGCGCACTGTGCCACAGGGGCTTCTCGCACCCGCACCGGCTGTCCGAGCACGTCATGTCCATGCACAGGTCAGTGCGAGTGTACAAGCACAAGTGCGCACTGTGCCACAGGGGCTTCTCGCACCCGCACCGGCTGTTCGAGCACGTCATGTCCATGCACAGGTCAGTGCGAGTGTACAAGCACAAGTGCGCACTGTGCCACAGGGGCTTCTCGCACCCGCACCGGCTGTTCGAGCACGTCATGTCCATGCCCAGGTCAGTGCGAGTGTACAAGCACAAGTGCGCACTGTGCCACAGGGGCTTCTCGCACCCGCACCGGCTGTCCGAGCACGTCATGTCCATGCACAGATCAGTGCGAGTGCACAAGCACAAGTGCGCACTGTGCCACAGGGGCTTCTCGCACCCGCACCGGCTGTCCGAGGACGTCATGTCCATGCACAGCTACCCGAGGTTGCACTTCCTCAAGCTGCACATACAATCGCATGCCAACGAGAATACTACGTCATAg
- Protein Sequence
- MSANNSKKGLVYDPGTCRCCGASKKCRLLNMEYEHQKKKEIYSDMFVECFGLVLSHLDGEPSDRLICAMCVGRLREACSFRRQVLECEERLLQARIHVHDAPMEIKTEIIKEEVSDDAINCDDGNHEDVMEIIDTANDTMEVPKDKCTEELSSNKSIEKKNEDRLQKELLLKIQGMKKRLKMIQSAKRKTEKPKKQPLPSPPVEKFVDEESIAFQNMLILIENSYVYPFQTAYSSFHCAYCGAMFPSPAPLRAHSLGHDPRKYRHVAAARPTYLDVRRTDCRLCDERPEDVRELQRHLATAHRLPIRRKINALMFRLTDGALSCIECDVSFMFFHALKRHMAVHFGNFVCDVCGEHYFDKSALEQHCRNTHRSDVKFTCHECGKLFKRQQALSMHLSCVHKKEPAFQCIKCEVSLYSAQERYKHMRDAHGVGRTHACEKCGKAYNSRGNLLEHNRTVHLRVYKHKCALCHRGFSHPHRLSEHVMSMHRSVRVYKHKCALCHRGFSHPHRLSEHVMSMHRSVRVYKHKCALCHRGFSHPHRLSEHVMSMHRSVRVYKHKCALCHRGFSHPHRLSEHVMSMHRSVRVYKHKCALCHRGFSHPHRLFEHVMSMHRSVRVYKHKCALCHRGFSHPHRLFEHVMSMPRSVRVYKHKCALCHRGFSHPHRLSEHVMSMHRSVRVHKHKCALCHRGFSHPHRLSEDVMSMHSYPRLHFLKLHIQSHANENTTS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -