Mfla010349.2


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Mecyna flavalis
Gene Symbol
-
Assembly
GCA_949319885.1
Location
OX439418.1:10655155-10658478[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.00047 0.041 15.2 3.2 1 23 319 341 319 341 0.99
2 16 5.9 5.2e+02 2.3 0.1 2 23 345 366 344 366 0.91
3 16 0.19 17 7.0 1.7 3 23 373 394 371 394 0.95
4 16 0.0082 0.72 11.3 0.4 2 23 449 471 448 471 0.96
5 16 0.0022 0.19 13.1 4.2 1 23 477 500 477 500 0.96
6 16 0.039 3.4 9.2 1.0 1 21 504 524 504 525 0.93
7 16 0.0064 0.56 11.7 3.1 1 23 533 556 533 556 0.96
8 16 0.11 9.4 7.8 1.6 1 23 561 584 561 584 0.94
9 16 0.0021 0.19 13.2 1.6 3 23 598 618 596 618 0.95
10 16 0.029 2.6 9.6 1.1 1 23 623 645 623 645 0.98
11 16 4.7e-06 0.00041 21.5 0.6 1 23 681 703 681 703 0.98
12 16 0.7 62 5.2 1.1 2 23 750 772 749 772 0.95
13 16 0.00027 0.024 16.0 2.5 1 23 778 800 778 800 0.98
14 16 0.00011 0.0098 17.2 3.7 2 23 807 828 806 828 0.97
15 16 0.21 18 6.9 0.6 1 23 834 857 834 857 0.88
16 16 1.7 1.5e+02 4.1 1.1 3 23 864 885 863 885 0.95

Sequence Information

Coding Sequence
ATGCTGAATGTTGAAGACTCTGCAACTCTTGTGAATAAAACAGACCAGATACTAATGCAAACGAATGAAGACGGGATGACCAACATGCAACATCTTACACAGAAGTTGCGGTACATTTTTCATACAACTCGGTTCTGTGGCATATGCTTAGATGTTGATGGTTCTGAGAAAATGTGGCCAATCGACACAGAGTTTGATATTGCTGTCGAAGAGCAGACTCACAAGAAGTTTCTTCGGGACATTGTTGATTATATACTGAATGGACAaAGTCAGCAAACTATGGCAAGTTCTTATTTATGCAGCCATTGTACAGAAAAATCTATACAGTCATACCTTTTCATCTACAATGCAAGGCAACTCTCGAAAATTATAAACAACTGTATCAATGAGCTTCACCAAAAAACTGTCCAAGTTAATAATGAAGTAGACACAATTAAATATATTGAAAATTCTAATGTTGTTATTTTGTTAGAGCAGAACAATGAAATGTGTGATTACATAGACATTGGGAAAATGACTGAAATAGTGGCCAAAGAGACAATTAAAGATGATGAAATAGGTACAGttaatatgaataatattaaaaatgaaattgttAAGAAAACAGATGAGTTGATTCCTACACCTATTGATTTAAAGGAATTccaaattgaaaattttaaagtcAGTGATGAACAATATGTACTTTTGAACTCTGAAAATTCTCACGAAATAGAAATAACATATTTAGATGAAGATTTGCAGTGTCCTACAGATATAGATGAACCGCAAAATGTggctgaaaataataatttgtgtaCTTCAGAAAGTTCAAATCCAAGAAAAAAGAAGGCAAGAGTAATGCAAAAAATTACATTCTCGTGTAAAAGATGCAGGGTCATATTACCATCTTATAAGTCACGGAAAGAACATTACAAAAATtgtaagaaacaaaaaatagaTCCAAATAAGTTATTCAAGTGTAAACTTTGTAATGACACATTTATATCCCAGAGATCTTTGAATACTCACTATAagacacatttaaaaatacgaTGTAAAGTGTGTCAATTTATTGTATCCGAAGAAGATATTACAGAACATATGAAAATAAATCATGAAGATTATGTACATTTGTGCAAATTATGTAAATTCTTCTCTTATACTGCTGAAGGATTAAATGTTCACATAAAAAAGTTACATAGCGGACCACAATGCGCGTTATGCTTCAAGAAAGTAAAAGAAAGAGACTTAAAACATCATAAGTGTAAGTTCAACTGTACAGAATGTATAGATAATATCTGTATCCACTATAAGTACTTAGTTTCGTATAGAGATCAAATTTTGAATAAAACTGATACTATTAAATGCTTTGATTGCGACTATGTATGTCCGAGAAGAGAAGCTTTACTAGGGCATGTAAACAGGGAACATTTGGATCACCATCCCTACACATGCGCCCATTGTGATCAGCAGTTTTATTCTCGTACCACTCTACGATACCATATAAACCAATTTCATAGAGAACGACACATCTGTTCTTTCTGCGATCAAGAATTCTTCACAAAAACATCTCTCGATAATCATGTGAAGCTGTGCCAATGTATCGAAAGAGATTTTAAGTGCGACCACTGCACTTGTTCTTTTAGTGCTTTAGAAGAGTTGGCCAATCACGTCAAGTTGAGACATGACCAAGAcacatttaattgtaatttatgtgAAAAGAAATTCTTATCTAGTGTAAAACTTCAAGATCACACATTCAAAGTACATAATGGCTTGCAAATAAAAAGGAAACGCACTCTTCTAGACTGCCCTGTGTGCAATGAGAAGTGTAAAAATAGAAGGCAATTATTGCAACATATAACGTTACATCCTAATGCAAGATTCCCTTGTAAAGAATGTAACATGGACTTTGATTGCATAAAAAAACTTCAAGCTCATATCAGAATACATTACGACGATGTGATTCAATGCGTTAATTGCAACAAAGTTTTAACGAAAGGATTTTTCCCCCACCACATGGTGTATTGTAATGCTGGCAGGCCGGCTGAGAATATTTACACCTGCGAAACTTGTGGAAGATCCTATTCTAACGAAGTCCAACTGAAAATCCATCGCAAAGTCCATTTGGAAAAGGTCCCCTGTCCTGCTTGTCAGAAGCCAACCAGGCCAGGTTACATGAAAGGACATTTGAAGCGTTGTAAGCCAAAGAAGAATAAAGTGCACCAGCAATTGAAATCTAAAAATAAGTACGTGAAATACATTAAATGCGACTTTTGTGATCATTTAATGTCTAGATATACAGAATTAGAAGCTCACGTTAACAGATTTCATTTGAAAGTAAAGCCgtataaatgtaattattgccaGAAGACATTCTTTGGAAAAGAACGTTTGAAGGACCATTTAGTAACGCATACTTCGGTTAAGAATGTATACTGCAGCGTTTGTAACAAGAAATTCCAGAACAATGCTTGTCTCAAACTGCATATGAGGAAGCACACTGGATATACGCCATACGCGTGTGAAATTTGCGGGGATAGATTTAGAACATCAAGTATAATGAATACGCATAAAGTTAAAAAGCACTCTGAGAGGACAGTGGCTTGCCCTCTCTGTGATGCGATGTTCCATTTGACAAGAGAAATGAGGAGTCACTTTAAAAAAGTTCATTGGAAGCAGAAAGGCAAGAAGTTTGATCCACGTGACGTGAAGGAACTAAGCCCTGCGTTTTACCATTTGTTTGAAGATGGTAGACTGCCTAAAGTAGAAGGCGAAGATTTGTATATTTCTTCGAAGTTCAATGAAAAATATGACTAG
Protein Sequence
MLNVEDSATLVNKTDQILMQTNEDGMTNMQHLTQKLRYIFHTTRFCGICLDVDGSEKMWPIDTEFDIAVEEQTHKKFLRDIVDYILNGQSQQTMASSYLCSHCTEKSIQSYLFIYNARQLSKIINNCINELHQKTVQVNNEVDTIKYIENSNVVILLEQNNEMCDYIDIGKMTEIVAKETIKDDEIGTVNMNNIKNEIVKKTDELIPTPIDLKEFQIENFKVSDEQYVLLNSENSHEIEITYLDEDLQCPTDIDEPQNVAENNNLCTSESSNPRKKKARVMQKITFSCKRCRVILPSYKSRKEHYKNCKKQKIDPNKLFKCKLCNDTFISQRSLNTHYKTHLKIRCKVCQFIVSEEDITEHMKINHEDYVHLCKLCKFFSYTAEGLNVHIKKLHSGPQCALCFKKVKERDLKHHKCKFNCTECIDNICIHYKYLVSYRDQILNKTDTIKCFDCDYVCPRREALLGHVNREHLDHHPYTCAHCDQQFYSRTTLRYHINQFHRERHICSFCDQEFFTKTSLDNHVKLCQCIERDFKCDHCTCSFSALEELANHVKLRHDQDTFNCNLCEKKFLSSVKLQDHTFKVHNGLQIKRKRTLLDCPVCNEKCKNRRQLLQHITLHPNARFPCKECNMDFDCIKKLQAHIRIHYDDVIQCVNCNKVLTKGFFPHHMVYCNAGRPAENIYTCETCGRSYSNEVQLKIHRKVHLEKVPCPACQKPTRPGYMKGHLKRCKPKKNKVHQQLKSKNKYVKYIKCDFCDHLMSRYTELEAHVNRFHLKVKPYKCNYCQKTFFGKERLKDHLVTHTSVKNVYCSVCNKKFQNNACLKLHMRKHTGYTPYACEICGDRFRTSSIMNTHKVKKHSERTVACPLCDAMFHLTREMRSHFKKVHWKQKGKKFDPRDVKELSPAFYHLFEDGRLPKVEGEDLYISSKFNEKYD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-