Basic Information

Insect: Mecyna flavalis
Gene Symbol: pol
Assembly: GCA_949319885.1
Location: OX439421.1:6716115-6736301[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.0027 0.24 12.8 1.9 1 23 955 977 955 977 0.98

2 8 2.7 2.4e+02 3.4 3.0 1 21 1017 1037 1017 1040 0.74

3 8 7e-06 0.00062 21.0 0.4 2 23 1047 1068 1047 1068 0.98

4 8 1.4e-06 0.00013 23.2 0.6 1 23 1074 1096 1074 1096 0.98

5 8 0.0004 0.035 15.5 0.7 1 23 1111 1134 1111 1134 0.97

6 8 0.012 1 10.8 0.2 1 23 1140 1163 1140 1163 0.96

7 8 2.9e-05 0.0026 19.0 3.1 1 23 1174 1196 1174 1196 0.98

8 8 7.6e-05 0.0067 17.7 1.5 1 23 1202 1225 1202 1226 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.0027	0.24	12.8	1.9	1	23	955	977	955	977	0.98
2	8	2.7	2.4e+02	3.4	3.0	1	21	1017	1037	1017	1040	0.74
3	8	7e-06	0.00062	21.0	0.4	2	23	1047	1068	1047	1068	0.98
4	8	1.4e-06	0.00013	23.2	0.6	1	23	1074	1096	1074	1096	0.98
5	8	0.0004	0.035	15.5	0.7	1	23	1111	1134	1111	1134	0.97
6	8	0.012	1	10.8	0.2	1	23	1140	1163	1140	1163	0.96
7	8	2.9e-05	0.0026	19.0	3.1	1	23	1174	1196	1174	1196	0.98
8	8	7.6e-05	0.0067	17.7	1.5	1	23	1202	1225	1202	1226	0.94

Sequence Information

Coding Sequence: ATGCCTTCGGACACCCGGCGCAGCAAACAAAAAGGAAGGCACCGTACAACGACGCCTTCCCCTTCTCGCACCGCGATGGAAGCGATCCTAAAGCGATTAGAAGCCCTTGAAAAAGGAACACGTGTTGACGCCAATCTTCAACCTGCTGTTGCTGGGCACGAGCAAGCAATTGTTCGGGTGCCTAGTGCTACGCATCAAGACCCTGCACCTTCAGTCGCGTCGGGAGCATCGCTGGATTCCACAAACCAGTTGCTGCCTGTGGAGCCTGCGCGAGGCGAGCGGAGCGCCGCCGTGCCTTCGTCTACGCCGAGTACGCCGCCACGTGACGCGGGGGACGCGAGGACTGCAGCGGAGCGACTACTGGCAGCGCTGACCTCTATCCCGGTGAGATCGAACCAATATTTTGTCTCTGATTTTGACCCTGGTGTTCATGATGTCGATGCGTGGTGTGACGAAGTAGATAAGGCTCGTATTTTGAACCGTTGGGACGACACGGAATGCCTTGCTCGCGTTGGTCATTGTTTGAAGGGTGAATCTCGCACCTGGCTGAGCCAGTGGACGAGCACTGTGCGTAATTGGTCCAATTTCAAATTAGAATTAAAAGCGTTATGCCCACGTAATATCGACATTGCGAACATTCTTTATGACGTCATGCGAACAGAGTCTGATAAATTCTCCACGTACGCGGAGTATGCACGCAGCGACGTATTAGATGTCTCGCAGGTAGATAAAAGCCCTCTTTCAGAAAAAGTCAATACTCCTGCCGTAGGCGATGACAGGAAGAACCTTCTTACTGTCCTTACTAAATATTCAGATCATTTTCTTAGTGGTACGGCTACCACGACTGTCAAAGATAGTGAGATGCAGATTAATTTGACTAGTGATGTGCCCGTGTATTATCGGCCGTATAAAATGTCGCATGATGAAAAACTGCGGGTCCGTTCCATAGTAAATGATTTGCTCGACAAGGGAATAATAAGAGAGTCAGATTCCGCGTATGCGAGTCCAGTTCTACTGGTTAAAAAGAAGGATGGTACAGACAGGATGGTAGTCGACTATAGAGCGCTTAATCAAATAACTGTTAAAGTTAGGCATCCGCTTCCACTGATTAATGACCATGTGGATAGGCTAGGTAAGGCTAAGGTTTTTAGTGCGCTCGATATGGTATCTGGTTTCCACCAATTGAGGGTTAGTGAGGACTCAATCCACAAGACAGCCTTCGTAACGCCCGAAGGGCATTACGAATATTGTAAAATGCCTTACGGACTTGCTAACGCTCCAATTATCTACCAGAAAACCATCACGAAAACATTAAAACCCTTCATAGATGCAGGAAAAGTACTGGTTTATATCGACGATGTACTTTTACTAACGAATTCAATATCCGAAAACCTTATTCTACTAGATTCTGTGTTAAAAACTTTAACCGAAGCCGGATTTTCAATCAATCTTAAGAAATGCACTTTTCTTACTGACGAAGTAGAATACCTCGGTAGAAAAATAGGTCAAGGTCAGGTACGGCCGAGCGAGCACAAAATTGAGGCTCTAGTCAGGTCACCGCCACCAACTACAGTCAAACAAGTTCGTCAGTTTCTGGGTTTGGCGGGATACTTCCGTCGGTACATACCAAACTACGCGTTAAAAACAGCGTGTATTGCTGCACTGACTAAGAAAGGAGTTAATTTTCATTGGGGAGACGAGCAGGAAAAGGCCCGTCAAGATATTATAGCCCGGCTAACCGACGAACCTGTGTTGACTATATTTGACCCAGAACTACCGACTGAGTTACATACGGACGCTAGTTCGATTGGCTATGGTGGTATATTGATGCAAACGCAAAAAGACAGCCGAAAGAAAGTAGTTGCGTATTTCAGTAAATTGACGCTTGTGACGAGACCGAAGACCCTGCTGACGATGCCACAGCTGGGCCATCTTCAGAACGCTCGTGAAGGCCGCGAGGACGCTGCCCCGTCAGGAGAGGCCGTGTTAGAAGTGAGAAGACCCCCTCCCTGGCAATACCGTCGCGTCACGCCACTGCCTCTATATAAGGAGCTCGCGCGCCAGTCACAAGCCTATTTGCCCGTCAGCCACCGAAGAGGAAACATCAAGCTAGAAGCTCTGCCCGATTTTCCCctcGTGATGGAGTCAGATGGCCTACCACAATGGCTGTGCTGGGAGTGTGCCGCACTTCTTCAGAAGTCGGTCCGTTTTAAACTCAAGATGTTGCGGGCCCACAACTTACTGTACGATTCCCTGTCACGTGGTGCTCCTTTCCCCGCAGACGCTGCTGAAGACCCAGAATTGAGGAAGCATGCCTCACCGCAACTCAGCGTCAGTAAAACCCGAACTTACTCAATAGCTGGCCAGGGGAAGATGGGTTTCCACGAGGAGGCGACGCACAAGTCTTCCCCCACAACGGCCCAGTCGTTCCTAGCCTCGCTGCATTCATACTCGCAGCCAGCAACGGCCCAGGTCCACCCAGCCTCCTTACCATCATACTCCCAGCCGCTGTCTCTCTCGGAGCAGCTCCCTGGCGCGACCCTGGTCAAGATCGAGGACGACGCGGACTTCGGCTGTAATGATGACCTCTTGGAGGAGTATAGGGTGTCAGATATAGACTCGCAGCATCTTCTAGAAGCAATGAGCGCGATAAAGCCTAAACAGGAGCCTGAgccgaagaagaagaaggaaaTTAAGATGAAAGAAGATATAGTTGAGAAGAAAAAGATAGAGGAAAAACAACCAGAGGATGTGAAACCATCGACATCGATCAACAAGAGTGAATATTTGGACCCCACCAAGATCAGGATTGTGACCCTTGACCCTGTGGAACAGATGCGACAGAAAGAGTCCCGAGGCCGGTTTGAATGCAAATACTGCCACACGTACTCAACAAATGCGTACGGCTTAGAAATGCATTTACTCACCCACACGCAGCGCTACGAGTGCGTCGAATGCAAAATCCGCATGACCAATCTCCCCTCCATAATGGACCATTACAGGTACGAGGCCAGTACAGTATCACAACACGAAGGCATAAAGAATACATTCAAATGCAAAATTTGCGGGAAATTGTCTAACAACAGACGGACGCACAGAGGCCACAAGCGTGACTACCACGGCGGCGGGGAGAGGCCCAAGTGCGACCAGTGCGGGAAGTCTTTCATTAATAAGAACTCGCTGATTGAACATCTGCAAATCCACCAAAATGTCAGGAACTTTGAGTGCGAGGAATGCGGGAAGAGGTTCCGCACGCGATGGGCGCTCAAAATCCACCTATCAAAGCACATAAACGTCAAAAATTTCAACTGCGTCGAGTGCGACATTGGGTTCAACTGCGACCAATGCGACAAACGGTACGAGACCGAGCGCGCCCTTCGCACTCACGTGCTCACCAAGCACGAGGGCGTCCGCGACTACCGCTGCGACCAGTGCCCCGCCGTGTACTCGCATGGCGTCTCGCTGGACAGGCACATCTACAGCGCGCACCGCGGCCGCAGACCGCGCGCGCCGACCATGCACGTCTGCGCAGTCTGCGGGAAGGCCTTTAAGACCAAGACCATACTGACGCACCACATGCGCACTCACACGGGCGAGAAGCCGTTCGCGTGCGAGATCTGCGGAAGAAGCTTCTCGCAGCGCTCCTCCAGGAACACGCACGTGAAGCTCGTGCATcacaagaacaagaccaaggtCAGTGCTATAGTAGTCACAGAAACGGGCGTAGCTACAGTGGGGCGCGGTGTGACTAGCCCTACCGTGCCGCGAGTATAG
Protein Sequence: MPSDTRRSKQKGRHRTTTPSPSRTAMEAILKRLEALEKGTRVDANLQPAVAGHEQAIVRVPSATHQDPAPSVASGASLDSTNQLLPVEPARGERSAAVPSSTPSTPPRDAGDARTAAERLLAALTSIPVRSNQYFVSDFDPGVHDVDAWCDEVDKARILNRWDDTECLARVGHCLKGESRTWLSQWTSTVRNWSNFKLELKALCPRNIDIANILYDVMRTESDKFSTYAEYARSDVLDVSQVDKSPLSEKVNTPAVGDDRKNLLTVLTKYSDHFLSGTATTTVKDSEMQINLTSDVPVYYRPYKMSHDEKLRVRSIVNDLLDKGIIRESDSAYASPVLLVKKKDGTDRMVVDYRALNQITVKVRHPLPLINDHVDRLGKAKVFSALDMVSGFHQLRVSEDSIHKTAFVTPEGHYEYCKMPYGLANAPIIYQKTITKTLKPFIDAGKVLVYIDDVLLLTNSISENLILLDSVLKTLTEAGFSINLKKCTFLTDEVEYLGRKIGQGQVRPSEHKIEALVRSPPPTTVKQVRQFLGLAGYFRRYIPNYALKTACIAALTKKGVNFHWGDEQEKARQDIIARLTDEPVLTIFDPELPTELHTDASSIGYGGILMQTQKDSRKKVVAYFSKLTLVTRPKTLLTMPQLGHLQNAREGREDAAPSGEAVLEVRRPPPWQYRRVTPLPLYKELARQSQAYLPVSHRRGNIKLEALPDFPLVMESDGLPQWLCWECAALLQKSVRFKLKMLRAHNLLYDSLSRGAPFPADAAEDPELRKHASPQLSVSKTRTYSIAGQGKMGFHEEATHKSSPTTAQSFLASLHSYSQPATAQVHPASLPSYSQPLSLSEQLPGATLVKIEDDADFGCNDDLLEEYRVSDIDSQHLLEAMSAIKPKQEPEPKKKKEIKMKEDIVEKKKIEEKQPEDVKPSTSINKSEYLDPTKIRIVTLDPVEQMRQKESRGRFECKYCHTYSTNAYGLEMHLLTHTQRYECVECKIRMTNLPSIMDHYRYEASTVSQHEGIKNTFKCKICGKLSNNRRTHRGHKRDYHGGGERPKCDQCGKSFINKNSLIEHLQIHQNVRNFECEECGKRFRTRWALKIHLSKHINVKNFNCVECDIGFNCDQCDKRYETERALRTHVLTKHEGVRDYRCDQCPAVYSHGVSLDRHIYSAHRGRRPRAPTMHVCAVCGKAFKTKTILTHHMRTHTGEKPFACEICGRSFSQRSSRNTHVKLVHHKNKTKVSAIVVTETGVATVGRGVTSPTVPRV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -