Basic Information

Insect: Mecyna flavalis
Gene Symbol: -
Assembly: GCA_949319885.1
Location: OX439422.1:5235659-5240533[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.0033 0.29 12.6 1.1 1 23 284 307 284 307 0.96

2 10 0.0061 0.54 11.7 0.1 2 23 338 360 337 360 0.92

3 10 0.00049 0.043 15.2 0.2 1 23 382 404 382 404 0.99

4 10 0.016 1.4 10.4 0.2 1 21 408 428 408 431 0.89

5 10 0.0019 0.17 13.3 0.4 1 23 438 461 438 461 0.96

6 10 0.46 41 5.8 2.8 1 20 467 486 467 490 0.76

7 10 3.5e-08 3e-06 28.2 2.0 1 23 497 519 497 519 0.99

8 10 0.0013 0.12 13.8 3.0 2 23 526 547 525 547 0.96

9 10 6.6e-06 0.00058 21.1 2.2 1 23 553 575 553 575 0.98

10 10 9.5e-07 8.3e-05 23.7 1.8 1 23 581 603 581 604 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.0033	0.29	12.6	1.1	1	23	284	307	284	307	0.96
2	10	0.0061	0.54	11.7	0.1	2	23	338	360	337	360	0.92
3	10	0.00049	0.043	15.2	0.2	1	23	382	404	382	404	0.99
4	10	0.016	1.4	10.4	0.2	1	21	408	428	408	431	0.89
5	10	0.0019	0.17	13.3	0.4	1	23	438	461	438	461	0.96
6	10	0.46	41	5.8	2.8	1	20	467	486	467	490	0.76
7	10	3.5e-08	3e-06	28.2	2.0	1	23	497	519	497	519	0.99
8	10	0.0013	0.12	13.8	3.0	2	23	526	547	525	547	0.96
9	10	6.6e-06	0.00058	21.1	2.2	1	23	553	575	553	575	0.98
10	10	9.5e-07	8.3e-05	23.7	1.8	1	23	581	603	581	604	0.96

Sequence Information

Coding Sequence: ATGGAGTCAGAATTCGCGACAACTTACGGACAATGCCGCTGCTGCTCCGCGGAAGGCAACCACAGGGATTTGACGAAGGAATATTGCTGGAACGGGATACGCGAAGTGTATTCCGATATATTTGTTGAATGTTTCAATTTACAcCTATCTCCAAAACAAGAGTTAACAAGTCTGATATGTTCAGATTGCATCCTCCGTCTGCGAGATGCGAGCAGCTTCCGTATTTTAGTTGTAAACACTGGACAGAAGTTACTGGAAGAGCTACAAGGTGGACAGCATACGCttataaaaattcaatGTGATGATAAAATCAGTGAAGACACCGTCAAACAGGAGTCCTATGAAGATGTGAAAGTGGAAACATGGGAAACGACGGGTCGCAGCGACGACGATTGGACTGACGATGATATGTTCGaagATAACATCTCCCTGCCATGTGATAAGGAGGTAGTAAAAGGTGAGCTGGAGCTGCGGTCCCGCTTCACTGCGCCCAAGCCGCTGCCCACGCGCGCGGCGTTGAAGAACATCTGCAAAACATACGTCAAGCATCTGGAATCATTGAAAGGTAAACAAATCGTTGGAAAATCATTAGAAAAGCTGATAGAATGTAAAACTGTTAAAATGAAGAGGAAGAAAACTGCAATTGAAACAGGAAATTCGGAGTCAGACATTCCAGAAACAGTTGCTAAGAAAAAACGGGTACAAAGAACCAAATACAGGGACAAAGAAATAGATTTAGATAAAGAAAAGAATCCATACACGGTAGAAAGATTGACACACGCAGCTAACATCACTGCGTTACTAGAATTTTCTAATTTAACTGCGTTTAAATCTAAGTTTCAACGAGCTTACCCTTGCTTCTACTGCGAACGACTATTTGAATACTTTGAAGAGCTTAAGAACCATCAAAAACTGGATCAtagtaaagaaaatataaacaaatgcGTCCTACAAAAGTATAGAGTGGGAAAACCTGACGGTTTAGTAGTATATGCTGATATTACAGATCTAAAATGCACTATTTGCAACAAAAACATACCAAGTTTAAAAGATTTGAAGGTACATCTAACTGGAGTACATGGTAAGAAGATGTACTTAGAATTATCCGATAGAGTGATACCGTTTAAAGTAAACGAGAACAATTTTCAGTGTCAAGTGTGTGGGACTTTGTACGAAACGTTTGGAGCTGTTGAGAGACACATGAATACTCACTATAGGAATTATGTTTGCGAAGAATGTGACTCTGGGTTTGTAACCAAGCAGCGGTTAAAGATACATGGGTACTTAATGCATAGTAGACGTCCCAATCAGTATCCTTGTGAAGTCTGTCAAAAGCAATTCGCAACGCAACAAAAGAAAAAGATTCATGTAGAAACAGTTCATGAAAATGTGAAAAAGTATAAGTGCAACCGTTGTCCGGAGCGgtttaatgaatattttcgtAGACATAAACATATGGTTTTAGTTCATGGAGTGGCTCCTTTAGAGTATAAATGCAACGTTTGTGATAAAACCTTTGATAGAAGATATGCTTTGTCAACTCATATGAGGACGCATATACAGCAGAAAGATGTGCAGTGCGAAATATGCCCATACAGATGCTTCACTAAAGTAGAATTAAGACATCACATGGTGAAGCATAATGGGGAGAGAATACACGAGTGTTCTGTTTGTAAAAAGTCATATGCAAGGGAGAAAACGTTAAAAGAACATATGAGAATACATACTAATGATAGGAGGTATGTTTGTCCGGTTTGTGGGCAGGCTTTTATACAGAATTGTAGCTTGAAAAGTCATATCAGGAGCCATCATAAGGAATATGGGTTGATGTAA
Protein Sequence: MESEFATTYGQCRCCSAEGNHRDLTKEYCWNGIREVYSDIFVECFNLHLSPKQELTSLICSDCILRLRDASSFRILVVNTGQKLLEELQGGQHTLIKIQCDDKISEDTVKQESYEDVKVETWETTGRSDDDWTDDDMFEDNISLPCDKEVVKGELELRSRFTAPKPLPTRAALKNICKTYVKHLESLKGKQIVGKSLEKLIECKTVKMKRKKTAIETGNSESDIPETVAKKKRVQRTKYRDKEIDLDKEKNPYTVERLTHAANITALLEFSNLTAFKSKFQRAYPCFYCERLFEYFEELKNHQKLDHSKENINKCVLQKYRVGKPDGLVVYADITDLKCTICNKNIPSLKDLKVHLTGVHGKKMYLELSDRVIPFKVNENNFQCQVCGTLYETFGAVERHMNTHYRNYVCEECDSGFVTKQRLKIHGYLMHSRRPNQYPCEVCQKQFATQQKKKIHVETVHENVKKYKCNRCPERFNEYFRRHKHMVLVHGVAPLEYKCNVCDKTFDRRYALSTHMRTHIQQKDVQCEICPYRCFTKVELRHHMVKHNGERIHECSVCKKSYAREKTLKEHMRIHTNDRRYVCPVCGQAFIQNCSLKSHIRSHHKEYGLM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00408712;
90% Identity: -
80% Identity: -