Basic Information

Insect: Mecyna flavalis
Gene Symbol: ZFX
Assembly: GCA_949319885.1
Location: OX439421.1:7093818-7097766[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 1.6e-05 0.0014 19.9 1.0 1 23 49 72 49 72 0.97

2 7 0.005 0.44 12.0 0.0 1 23 78 101 78 101 0.97

3 7 9.6e-08 8.4e-06 26.8 5.0 2 23 107 128 107 128 0.98

4 7 0.00014 0.013 16.8 1.5 1 23 134 157 134 157 0.95

5 7 1.5e-05 0.0014 19.9 0.9 1 23 166 189 166 189 0.98

6 7 6.4e-08 5.6e-06 27.4 1.7 2 23 198 219 198 219 0.98

7 7 6.6e-07 5.8e-05 24.2 1.6 1 23 225 248 225 249 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	1.6e-05	0.0014	19.9	1.0	1	23	49	72	49	72	0.97
2	7	0.005	0.44	12.0	0.0	1	23	78	101	78	101	0.97
3	7	9.6e-08	8.4e-06	26.8	5.0	2	23	107	128	107	128	0.98
4	7	0.00014	0.013	16.8	1.5	1	23	134	157	134	157	0.95
5	7	1.5e-05	0.0014	19.9	0.9	1	23	166	189	166	189	0.98
6	7	6.4e-08	5.6e-06	27.4	1.7	2	23	198	219	198	219	0.98
7	7	6.6e-07	5.8e-05	24.2	1.6	1	23	225	248	225	249	0.94

Sequence Information

Coding Sequence: ATGTTGGAGCAAAGGCCACCTTATGCCTTCTCGGACATCGTCGGGCGTCGTCGGGCGTCGCCGTCTCCCCACACCTGCGCGCACCATCACCGGGCCACCACACTCCGCGATTCGATCCCACCGGCAACGAGCGCGTTCCTCTTGTTCAACTGCGACCAATGCGACAAACGGTACGCGACCACGTACGCTCTTCGCAAGCACGTGCTCACCCAGCACGAGGGCGTCCGCGACTACCGCTGCGACCAGTGCCCCGCCGCGTACGCGTGGCGCAGGTCGCTGGAGAGGCACATCGACACCGCGCACCGCGGCGTGCGCGAAACCTGCGAAACCTGCGGGAAGGCCTTTAAGACCAAGCACAAGCTGACGCGCCACATGCGCACTCACACGGGCGAGAAGCCGTTCGCGTGCGAGCTCTGCGGGAGAGGGTTCTCGCGGCGCTGCTCCATGCAGTCGCACGTGAAGAACGTGCATCGCAAGAACAAGGGCGTGCGGGACTACCGCTGCGACCAGTGCCCCGCCGCGTACACCCGGCGCTACAAGCTGAAGAATCACATCGACACCAGGCACCGCGGCGAGCCGACCATGCGCGAAACCTGCGAAACCTGCGGGAAGGCCTTTCAGAACAAGACCGACCTGACGCGCCACATGCGCACTCACACGGGCGAGAAGCCGTTCGCGTGCGAGCTCTGCGGGAAAACCTTCTCGCAGAGCTCCAACATGAAGACGCACGTGAAGCTCGTGCATcacaagaacaagaccaagaccaaggtcAGTGCTATAGTAGTCACAGACACGGTGGGGCGCGGTGTGGCTAGCCCCACCCTGccgcgagtatag
Protein Sequence: MLEQRPPYAFSDIVGRRRASPSPHTCAHHHRATTLRDSIPPATSAFLLFNCDQCDKRYATTYALRKHVLTQHEGVRDYRCDQCPAAYAWRRSLERHIDTAHRGVRETCETCGKAFKTKHKLTRHMRTHTGEKPFACELCGRGFSRRCSMQSHVKNVHRKNKGVRDYRCDQCPAAYTRRYKLKNHIDTRHRGEPTMRETCETCGKAFQNKTDLTRHMRTHTGEKPFACELCGKTFSQSSNMKTHVKLVHHKNKTKTKVSAIVVTDTVGRGVASPTLPRV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -