Mfla012633.1
Basic Information
- Insect
- Mecyna flavalis
- Gene Symbol
- -
- Assembly
- GCA_949319885.1
- Location
- OX439422.1:5004434-5010257[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 22 0.00053 0.046 15.1 1.0 1 23 40 63 40 63 0.97 2 22 0.0018 0.16 13.4 0.1 1 23 69 92 69 92 0.93 3 22 0.0013 0.12 13.8 3.0 1 23 98 121 98 121 0.97 4 22 0.0021 0.18 13.2 1.1 1 23 143 166 143 166 0.97 5 22 0.0046 0.4 12.1 0.1 3 23 171 192 170 192 0.96 6 22 0.0076 0.67 11.4 1.3 1 23 198 221 198 221 0.95 7 22 0.00014 0.012 16.9 3.4 1 23 276 299 276 299 0.98 8 22 0.0022 0.2 13.1 0.2 1 23 305 328 305 328 0.93 9 22 0.0076 0.67 11.4 1.3 1 23 334 357 334 357 0.95 10 22 2 1.7e+02 3.8 1.2 1 23 363 385 363 385 0.95 11 22 0.00047 0.042 15.2 3.3 1 23 412 435 412 435 0.98 12 22 0.0022 0.2 13.1 0.2 1 23 441 464 441 464 0.93 13 22 0.0076 0.67 11.4 1.3 1 23 470 493 470 493 0.95 14 22 2 1.7e+02 3.8 1.2 1 23 499 521 499 521 0.95 15 22 0.00014 0.012 16.9 3.4 1 23 548 571 548 571 0.98 16 22 0.003 0.26 12.7 0.1 1 23 577 600 577 600 0.93 17 22 0.047 4.1 9.0 0.6 1 23 606 629 606 629 0.95 18 22 0.11 10 7.7 5.5 1 23 651 674 651 674 0.95 19 22 0.0045 0.39 12.2 0.1 2 23 679 701 679 701 0.95 20 22 4.4e-05 0.0039 18.5 1.2 1 23 707 730 707 730 0.97 21 22 5.5 4.9e+02 2.4 5.8 1 23 764 786 764 786 0.96 22 22 2.2e-05 0.0019 19.4 0.1 2 23 793 815 792 815 0.95
Sequence Information
- Coding Sequence
- ATGGCGGAAGCTCAAGTATCTCAAAGCCTGCAATCTTGGATTGCAGCCATGGCAACTGCAGCCTTTACGGGCAAGTTCCGACTCGGCGGCTTGGATTACACTCGCGTCGACAACTGGTACCAGTGCACTCGCTGCGAAAAGCGTTACGGCAGACTGGGCTCTCTCAGATCACACGTGGAAACTAAACATTATACGATACCGAGGTTCCTTTGCCCGTATTGCGATGAAGTGTTCATGACGCCCACTCGTCTTGCAGTCCACAAACTGAGCGTTCACAACGTCGATGACAGATTCAAATGTAACGCTTGCAATCACGTGTTTAACCTAAAGGTTCAGTTACGGAAGCACATAAACAACTTTCATAAGATGGGCAGTACGGGCAAGTTCCGATTCGGCGGCTCGGATTACACTCGCGTCGACAACTGGTACCAGTGCACCCGCTGCGAAAAGCGTTACGGCAAACTGGGCTCTCTCAGATCACATGTGGAAACTAAACATTATAAGATACTTTGCCCGTATTGCGATGAAGTGTTCATGACGCGCACTCGTCTTGCAGTCCACAAACTGAGCGTTCACAACGTCGATGACAGATTCAAATGTAACGCTTGCAATGGCGTGTTTAACCTAAAGTTTCAGTTACGGAAGCACATAGAAAACTTTCATAAGATGGGTGAGAGATTTAAGTGCGAGTTTTGTGAGTACGAGGCGTTCAGTGTCTACTATATGAACATGCACAAGATTAAGCATAAGACTGTGAAGGATCATCATTGCAGTACGGGCAAGTTCCGATTCGGCGGCTCGGATTACACTCGCGTCGATGACTGGTACCAGTGCACCCACTGCGATAAGCGTTACGGCAAACTGGGCTCTCTCAGATCACACGTGAAAACTAAACATTATACGATACCGAGGTTCCTTTGCCCGTATTGCGATGAAGTGTTCATGACGCGCACTCGTCTAGCAGTCCACAAACTGAGCGATCACAACGTCGATGACAGATTCAAATGTAACGCTTGTAATGGCGTGTTTAACCTAAAGTTTCAGTTACGGAAGCACATAGAAAACTTTCATAAGATGGGTGAGAGATTTAAGTGCGAGTTTTGTGAGTACGAGGCGTTCAGTGCCTACTATATGAACATGCACAAGATTAAGCATAAGACTGTGAAGGATCATCATTGCAGTACGGGCAAGTTCCGATTCGGCGGCTCGGATTACACTCGCGTCGATGACTGGTACCAGTGCACCCATTGCGAAAAGCGTTACGGCAAACTGGGCTCTCTCAGATCACACGTGAAAACTAAACATTATACGATACCGAGGTTCCTTTGCCCGTATTGCGATGAAGTGTTCATGACGCGCACTCGTCTAGCAGTCCACAAACTGAGCGATCACAACGTCGATGACAGATTCAAATGTAACGCTTGCAATGGCGTGTTTAACCTAAAGTTTCAGTTACGGAAGCACATAGAAAACTTTCATAAGATGGGTGAGAGATTTAAGTGCGAGTTTTGTGAGTACGAGGCGTTCAGTGCCTACTATATGAACATGCACAAGATTAAGCATAAGACTGTGAAGGATCATCATTGCAGTACGGGCAAGTTCCGATTCGGCGGCTCGGATTACACTCGCGTCGATGACTGGTACCAGTGCACCCACTGCGATAAGCGTTACGGCAAACTGGGCTCTCTCAGATCACACGTGAAAACTAAACATTATACGATATCGAGGTTCCTTTGCCCGTATTGCGATGAAGTGTTCATGACGGCCACTCGTCTTGCAGTCCACAAACTGAGCGTTCACAACGTCGATGACAGATTCAAATGTAACGCTTGCAATGGCGTGTTTAACCTAGAGTTTCAGTTACGGCAGCACATAGAAAACTTTCATAAGATAGGCAGTACGGGCAAGTTCCGATTCGACGGCTCGGATTACACTCGCGTCGACAACTGGTACCAGTGCACTCGCTGCGAAAAGCGTTACGAAAAACTGTGCTCTCTCAGATCACACGTTAAATTTAAACATGATAAGATACCGAGGTGCCCGTATTGCGATGAAGTGTTCATGACGCTCACTCGTCTTGCAGTCCACAAACTGAGCGTTCACAACGTCGATGACAGATTCAAATGTAACGCTTGCAATCGCGTGTTTAACGTGAAAGTTCAGTTACGAAGGCACATAAACAACTTTCATAAGATGGGTGAGAGATATAAGTGCGAGTTTTGTGAGTACGAGTCGTTCAGTGTCTGCTATATGAAAAGGCACAAGATTAAGCATAAGACTGTGAAGGATCATCATTGCAGGTTCTGTAAGAAGGCGTTCTTGAGTTCGTCGAATCGTTCTCTACATGAACGAATACATACTGGTGATAGGAAGAAGGTGTGCGCTGTTTGCGGGAAAGCGTTTGTGCAGAAGGCGAGTCTCAATTATCATATGGCGAAGTATCATCCGGAAGTCAACTTCTAG
- Protein Sequence
- MAEAQVSQSLQSWIAAMATAAFTGKFRLGGLDYTRVDNWYQCTRCEKRYGRLGSLRSHVETKHYTIPRFLCPYCDEVFMTPTRLAVHKLSVHNVDDRFKCNACNHVFNLKVQLRKHINNFHKMGSTGKFRFGGSDYTRVDNWYQCTRCEKRYGKLGSLRSHVETKHYKILCPYCDEVFMTRTRLAVHKLSVHNVDDRFKCNACNGVFNLKFQLRKHIENFHKMGERFKCEFCEYEAFSVYYMNMHKIKHKTVKDHHCSTGKFRFGGSDYTRVDDWYQCTHCDKRYGKLGSLRSHVKTKHYTIPRFLCPYCDEVFMTRTRLAVHKLSDHNVDDRFKCNACNGVFNLKFQLRKHIENFHKMGERFKCEFCEYEAFSAYYMNMHKIKHKTVKDHHCSTGKFRFGGSDYTRVDDWYQCTHCEKRYGKLGSLRSHVKTKHYTIPRFLCPYCDEVFMTRTRLAVHKLSDHNVDDRFKCNACNGVFNLKFQLRKHIENFHKMGERFKCEFCEYEAFSAYYMNMHKIKHKTVKDHHCSTGKFRFGGSDYTRVDDWYQCTHCDKRYGKLGSLRSHVKTKHYTISRFLCPYCDEVFMTATRLAVHKLSVHNVDDRFKCNACNGVFNLEFQLRQHIENFHKIGSTGKFRFDGSDYTRVDNWYQCTRCEKRYEKLCSLRSHVKFKHDKIPRCPYCDEVFMTLTRLAVHKLSVHNVDDRFKCNACNRVFNVKVQLRRHINNFHKMGERYKCEFCEYESFSVCYMKRHKIKHKTVKDHHCRFCKKAFLSSSNRSLHERIHTGDRKKVCAVCGKAFVQKASLNYHMAKYHPEVNF
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -