Mfla011108.1
Basic Information
- Insect
- Mecyna flavalis
- Gene Symbol
- ZFY
- Assembly
- GCA_949319885.1
- Location
- OX439420.1:1855936-1864128[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 31 0.041 3.6 9.1 0.6 5 21 178 194 177 195 0.92 2 31 0.78 69 5.1 7.8 2 23 224 245 223 245 0.95 3 31 2e-05 0.0018 19.5 3.2 1 23 256 278 256 278 0.98 4 31 0.0001 0.0092 17.3 2.1 1 23 286 309 286 309 0.97 5 31 2.2e-06 0.00019 22.6 3.5 1 23 340 362 340 362 0.98 6 31 5.5e-07 4.9e-05 24.4 0.9 1 23 368 390 368 390 0.96 7 31 3e-05 0.0027 19.0 0.5 1 23 396 418 396 418 0.99 8 31 2.6e-05 0.0023 19.2 0.5 1 23 424 446 424 446 0.98 9 31 7.1 6.2e+02 2.1 0.4 1 16 452 467 452 469 0.84 10 31 0.0025 0.22 12.9 0.7 6 23 497 514 497 514 0.98 11 31 7.1 6.2e+02 2.1 0.4 1 16 520 535 520 537 0.84 12 31 0.0025 0.22 12.9 0.7 6 23 565 582 565 582 0.98 13 31 7.1 6.2e+02 2.1 0.4 1 16 588 603 588 605 0.84 14 31 0.0025 0.22 12.9 0.7 6 23 633 650 633 650 0.98 15 31 7.1 6.2e+02 2.1 0.4 1 16 656 671 656 673 0.84 16 31 0.0025 0.22 12.9 0.7 6 23 701 718 701 718 0.98 17 31 7.1 6.2e+02 2.1 0.4 1 16 724 739 724 741 0.84 18 31 0.0025 0.22 12.9 0.7 6 23 769 786 769 786 0.98 19 31 7.1 6.2e+02 2.1 0.4 1 16 792 807 792 809 0.84 20 31 0.0025 0.22 12.9 0.7 6 23 837 854 837 854 0.98 21 31 7.1 6.2e+02 2.1 0.4 1 16 860 875 860 877 0.84 22 31 0.0025 0.22 12.9 0.7 6 23 905 922 905 922 0.98 23 31 7.1 6.2e+02 2.1 0.4 1 16 928 943 928 945 0.84 24 31 0.0025 0.22 12.9 0.7 6 23 973 990 973 990 0.98 25 31 7.1 6.2e+02 2.1 0.4 1 16 996 1011 996 1013 0.84 26 31 0.0025 0.22 12.9 0.7 6 23 1041 1058 1041 1058 0.98 27 31 7.1 6.2e+02 2.1 0.4 1 16 1064 1079 1064 1081 0.84 28 31 0.0025 0.22 12.9 0.7 6 23 1109 1126 1109 1126 0.98 29 31 0.00014 0.013 16.8 0.3 1 23 1132 1154 1132 1154 0.98 30 31 0.00014 0.012 16.9 2.1 1 21 1160 1180 1160 1182 0.96 31 31 1.4e-06 0.00012 23.2 0.4 1 23 1188 1210 1188 1210 0.98
Sequence Information
- Coding Sequence
- ATGGAAACGGCAACGACAGCGAACCTACATAAAATCTGCAGGACATGCTTGTACGAATCGCCTCGTATGGTGTCTTTAACGACCAAAATGGGGGATGGAAAACGAACTGTAAACGACATCTTATTATTTGTCCTAAATGATAATGTTACTGTAGGTCCTAGGTTCCCCCAACAGATATGCGAGGAGTGTGAACTGTTGTTGTGCAAATTAGACGAGTTTAAACAACGCTGCCACGATTCTGAGAAAGTTTTGAAAGATCTTCTAAATGTCTCTGATTTGGACTCTCTGCAAAGTGTTAAAGTGGAAAATTCGTCTAAATTAGATAAAAAGGCGCCTGTTGGGGATTACATTGACCTAAACCCGGTGAATATGATCTTACCCTTCAAAGAAGATGAAGAGAAGAAGGATTCTAAGGCTGATGTGAAAGATTCAATCAAACTTGAATTTGGTGATGATTTCTCTGACGGGTTCGACGAACCATTCGATGATGATGATCTTAATGATTTCGATAATAAGGCATCATACTTATGTACATGTAAAAAATCATTTTCCGATGCAAAAGAATATCAAAATCACCTAAATAATAAATGCTGTAAAAAACCagctaaaactaaaataaaaaaggaagagTCGACTAAACGGAAAAACAACACACTCCTAATGCCAGTGAAGTGCGAACATTGCGATCAcatatttaaaacaatgaaaTTGTTCAAAACACACTCATGTTTGCATAAAAAGGAGCCACAAGAAACGCAGGAATACTACCAATGTTCGATATGTACCAGAAAGTTTAAGAAGAAATCATCACTTGTAACACACTTGAAAAACCATGAAGAGAGGGACAACGTAAAATATACCTGTGAAACGTGTAAGAGAGAGTTCAAATATCAAGCACATTTAGATAACCACATGATATCAGAACATAATTCGAAGAAAGGTTTAAAACTATTGCAAATATATCCAATGGAAGAGCAAAGAGAGAATGTACAGACAGACAAATCAATTGAAAAGAAGCATAGCTGTAAGATGTGTGGTAAATCGTTTACGATGATGTCAACGCTGACAGATCACATGCGAACGCATACCGGTGAACGACCGTTCCTATGTTCTGTGTGTGGGAGAGGGTTTACACAGAAAACTAACTTAGCACAGCACATGAGAAGGCATTTAGGTTTGAAACCATTTAAGTGCGGAGAGTGTGAAAGGCGGTTCGTATCAAAGGGCGAGCTAGACGCGCACACGCGCAAGCACTCGGGCGCGCACCCGTTCGTGTGCGACGCGTGCGGCAACGGCTTCACCACGTCCTCGTCGCTGCGCAAGCACAAGCGCGTGCACACCGGCGAGCGCCCGTACGCCTGCGACCTCTGCCCGATGAAGTTTGCTGTCTCTGGTGAGTACTGTACTGGCTCTGGTGCAGTGCGGCAACGGCTTCACCACGTCCTCGTCGCTGCGCAAGCACAAGCGCGTGCACACCGGCGAGCGCCCTGCGGCAACGGCTTCACCACGTCCTCGTCGCTGCGCAAGCACAAGCGCGTGCACACCGGCGAGCGCCCGTACGCCTGCGACCTCTGCCCGATGAAGTTTGCTGTCTCTGGTGAGTACTGTACTGGCTCTGGTGCAGTGCGGCAACGGCTTCACCACGTCCTCGTCGCTGCGCAAGCACAAGCGCGTGCACACCGGCGAGCGCCCTGCGGCAACGGCTTCACCACGTCCTCGTCGCTGCGCAAGCACAAGCGCGTGCACACCGGCGAGCGCCCGTACGCCTGCGACCTCTGCCCGATGAAGTTTGCTGTCTCTGGTGAGTACTGTACTGGCTCTGGTGCAGTGCGGCAACGGCTTCACCACGTCCTCGTCGCTGCGCAAGCACAAGCGCGTGCACACCGGCGAGCGCCCTGCGGCAACGGCTTCACCACGTCCTCGTCGCTGCGCAAGCACAAGCGCGTGCACACCGGCGAGCGCCCGTACGCCTGCGACCTCTGCCCGATGAAGTTTGCTGTCTCTGGTGAGTACTGTACTGGCTCTGGTGCAGTGCGGCAACGGCTTCACCACGTCCTCGTCGCTGCGCAAGCACAAGCGCGTGCACACCGGCGAGCGCCCTGCGGCAACGGCTTCACCACGTCCTCGTCGCTGCGCAAGCACAAGCGCGTGCACACCGGCGAGCGCCCGTACGCCTGCGACCTCTGCCCGATGAAGTTTGCTGTCTCTGGTGAGTACTGTACTGGCTCTGGTGCAGTGCGGCAACGGCTTCACCACGTCGTCGTCGCTGCGCAAGCACAAGCGCGTGCACACCGGCGAGCGCCCTGCGGCAACGGCTTCACCACGTCCTCGTCGCTGCGCAAGCACAAGCGCGTGCACACCGGCGAGCGCCCGTACGCCTGCGACCTCTGCCCGATGAAGTTTGCTGTCTCTGGTGAGTACTGTACTGGCTCTGGTGCAGTGCGGCAACGGCTTCACCACGTCCTCGTCGCTGCGCAAGCACAAGCGCGTGCACACCGGCGAGCGCCCTGCGGCAACGGCTTCACCACGTCCTCGTCGCTGCGCAAGCACAAGCGCGTGCACACCGGCGAGCGCCCGTACGCCTGCGACCTCTGCCCGATGAAGTTTGCTGTCTCTGGTGAGTACTGTACTGGCTCTGGTGCAGTGCGGCAACGGCTTCACCACGTCCTCGTCGCTGCGCAAGCACAAGCGCGTGCACACCGGCGAGCGCCCTGCGGCAACGGCTTCACCACGTCCTCGTCGCTGCGCAAGCACAAGCGCGTGCACACCGGCGAGCGCCCGTACGCCTGCGACCTCTGCCCGATGAAGTTTGCTGTCTCTGGTGAGTACTGTACTGGCTCTGGTGCAGTGCGGCAACGGCTTCACCACGTCCTCGTCGCTGCGCAAGCACAAGCGCGTGCACACCGGCGAGCGCCCTGCGGCAACGGCTTCACCACGTCCTCGTCGCTGCGCAAGCACAAGCGCGTGCACACCGGCGAGCGCCCGTACGCCTGCGACCTCTGCCCGATGAAGTTTGCTGTCTCTGGTGAGTACTGTACTGGCTCTGGTGCAGTGCGGCAACGGCTTCACCACGTCCTCGTCGCTGCGCAAGCACAAGCGCGTGCACACCGGCGAGCGCCCTGCGGCAACGGCTTCACCACGTCCTCGTCGCTGCGCAAGCACAAGCGCGTGCACACCGGCGAGCGCCCGTACGCCTGCGACCTCTGCCCGATGAAGTTTGCTGTCTCTGGTGAGTACTGTACTGGCTCTGGTGCAGTGCGGCAACGGCTTCACCACGTCCTCGTCGCTGCGCAAGCACAAGCGCGTGCACACCGGCGAGCGCCCTGCGGCAACGGCTTCACCACGTCCTCGTCGCTGCGCAAGCACAAGCGCGTGCACACCGGCGAGCGCCCGTACGCCTGCGACCTCTGCCCGATGAAGTTTGCTGTCTCTGGCACCCTGAAGAGTCACCGTCGCACCCACACAGGCGAGAAGCCGTATCAATGCTCGTACTGTGAGAAAGCCTTCGTCCAGCGCCAGGATCTGGTCTCCCACATCCGCTGCCACACTGGGGAGCGGCCCTTTGTCTGCGCACACTGTGGACAGGCATTCCGGAAGCCGTCAGCACTGAAAGCGCACGTGAAGACCCACAAGCTgggcccgccgccgcccgccatGCTGGGGGGACTGCAGCCGCTCAGCctgctgcagggactccagggGACCAGCTAA
- Protein Sequence
- METATTANLHKICRTCLYESPRMVSLTTKMGDGKRTVNDILLFVLNDNVTVGPRFPQQICEECELLLCKLDEFKQRCHDSEKVLKDLLNVSDLDSLQSVKVENSSKLDKKAPVGDYIDLNPVNMILPFKEDEEKKDSKADVKDSIKLEFGDDFSDGFDEPFDDDDLNDFDNKASYLCTCKKSFSDAKEYQNHLNNKCCKKPAKTKIKKEESTKRKNNTLLMPVKCEHCDHIFKTMKLFKTHSCLHKKEPQETQEYYQCSICTRKFKKKSSLVTHLKNHEERDNVKYTCETCKREFKYQAHLDNHMISEHNSKKGLKLLQIYPMEEQRENVQTDKSIEKKHSCKMCGKSFTMMSTLTDHMRTHTGERPFLCSVCGRGFTQKTNLAQHMRRHLGLKPFKCGECERRFVSKGELDAHTRKHSGAHPFVCDACGNGFTTSSSLRKHKRVHTGERPYACDLCPMKFAVSGEYCTGSGAVRQRLHHVLVAAQAQARAHRRAPCGNGFTTSSSLRKHKRVHTGERPYACDLCPMKFAVSGEYCTGSGAVRQRLHHVLVAAQAQARAHRRAPCGNGFTTSSSLRKHKRVHTGERPYACDLCPMKFAVSGEYCTGSGAVRQRLHHVLVAAQAQARAHRRAPCGNGFTTSSSLRKHKRVHTGERPYACDLCPMKFAVSGEYCTGSGAVRQRLHHVLVAAQAQARAHRRAPCGNGFTTSSSLRKHKRVHTGERPYACDLCPMKFAVSGEYCTGSGAVRQRLHHVVVAAQAQARAHRRAPCGNGFTTSSSLRKHKRVHTGERPYACDLCPMKFAVSGEYCTGSGAVRQRLHHVLVAAQAQARAHRRAPCGNGFTTSSSLRKHKRVHTGERPYACDLCPMKFAVSGEYCTGSGAVRQRLHHVLVAAQAQARAHRRAPCGNGFTTSSSLRKHKRVHTGERPYACDLCPMKFAVSGEYCTGSGAVRQRLHHVLVAAQAQARAHRRAPCGNGFTTSSSLRKHKRVHTGERPYACDLCPMKFAVSGEYCTGSGAVRQRLHHVLVAAQAQARAHRRAPCGNGFTTSSSLRKHKRVHTGERPYACDLCPMKFAVSGEYCTGSGAVRQRLHHVLVAAQAQARAHRRAPCGNGFTTSSSLRKHKRVHTGERPYACDLCPMKFAVSGTLKSHRRTHTGEKPYQCSYCEKAFVQRQDLVSHIRCHTGERPFVCAHCGQAFRKPSALKAHVKTHKLGPPPPAMLGGLQPLSLLQGLQGTS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -