Basic Information

Insect: Mecyna flavalis
Gene Symbol: -
Assembly: GCA_949319885.1
Location: OX439435.1:12841493-12864476[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 7.9e-05 0.007 17.7 2.2 1 23 422 444 422 444 0.97

2 16 0.0041 0.36 12.3 0.6 1 20 450 469 450 472 0.94

3 16 2.1e-05 0.0018 19.5 5.6 1 23 491 513 491 513 0.98

4 16 9.6e-05 0.0085 17.4 4.1 1 23 519 541 519 541 0.99

5 16 3.5e-05 0.0031 18.8 5.3 1 23 547 569 547 569 0.97

6 16 5.2e-05 0.0046 18.2 8.1 1 23 575 597 575 597 0.97

7 16 7.1e-07 6.2e-05 24.1 2.9 1 23 603 625 603 625 0.97

8 16 0.0001 0.0089 17.3 6.7 1 23 631 653 631 653 0.97

9 16 0.0001 0.0088 17.4 6.5 1 23 659 681 659 681 0.97

10 16 4.8e-07 4.2e-05 24.6 1.9 1 23 687 709 687 709 0.98

11 16 4.9e-05 0.0043 18.3 7.9 1 23 715 737 715 737 0.98

12 16 5.5e-06 0.00048 21.3 7.0 1 23 743 765 743 765 0.98

13 16 1.7e-05 0.0015 19.7 8.1 1 23 771 793 771 793 0.97

14 16 1.7e-06 0.00015 22.9 1.9 3 23 801 821 799 821 0.97

15 16 0.00072 0.064 14.6 0.3 1 23 828 850 828 850 0.96

16 16 0.11 9.3 7.8 4.1 1 23 861 883 861 883 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	7.9e-05	0.007	17.7	2.2	1	23	422	444	422	444	0.97
2	16	0.0041	0.36	12.3	0.6	1	20	450	469	450	472	0.94
3	16	2.1e-05	0.0018	19.5	5.6	1	23	491	513	491	513	0.98
4	16	9.6e-05	0.0085	17.4	4.1	1	23	519	541	519	541	0.99
5	16	3.5e-05	0.0031	18.8	5.3	1	23	547	569	547	569	0.97
6	16	5.2e-05	0.0046	18.2	8.1	1	23	575	597	575	597	0.97
7	16	7.1e-07	6.2e-05	24.1	2.9	1	23	603	625	603	625	0.97
8	16	0.0001	0.0089	17.3	6.7	1	23	631	653	631	653	0.97
9	16	0.0001	0.0088	17.4	6.5	1	23	659	681	659	681	0.97
10	16	4.8e-07	4.2e-05	24.6	1.9	1	23	687	709	687	709	0.98
11	16	4.9e-05	0.0043	18.3	7.9	1	23	715	737	715	737	0.98
12	16	5.5e-06	0.00048	21.3	7.0	1	23	743	765	743	765	0.98
13	16	1.7e-05	0.0015	19.7	8.1	1	23	771	793	771	793	0.97
14	16	1.7e-06	0.00015	22.9	1.9	3	23	801	821	799	821	0.97
15	16	0.00072	0.064	14.6	0.3	1	23	828	850	828	850	0.96
16	16	0.11	9.3	7.8	4.1	1	23	861	883	861	883	0.99

Sequence Information

Coding Sequence: ATGAATCCTGAACACCATAGCATCAACACGGGGGGTGGCCAGCCTCCTGGAAGTTCAGAGTCTCAGAACCAAAGGGTTCAAACTGCGCAGCAACAGCAGCAGGCAGCTAATTTGCCCGCAACCACCTCTGCGACTGATCTCAGAGTTAATTCCGCGGCCGTGAACGTCGCTTTGTCTAGTGTCGCCAAATATTGGGTGTTTACGAATTTATTTCCTGGTCCAATACCACAAGTATCTGTGTATGGCTTGCCAACTGGGGCCCGGATCGAAAATGGAAAACCCGTACAGGACCTTGGTCAACATGCAAGCATACTCAACGGTGACCCAAATATCATATTGGGTCACCACGGTGGTCAACCGCAAGTCACCGTATCAGCCTCCGGGGCTCAACAAATACCTGTATCTCAAATTATTGCTACACAATCTGGACAACCACATGAAGCGTTGGTGGCCCACAACCAACAACAGGAGCTTCAACAGCAAGCTTCAGGCACCACTCAGGTCACTGTCAGTGCAGGCCAACCAAATCACCAGCAGGTACCCAATAACCGGGTCGAGTTTGTACAACACCATAACATTGATATGGTAAATCACGTGGGGCATCATTCACAACAGCACTTAATGCAGCAGCAACTTATGGCCAGTGCCCGTCCGGAACACTCAAATCAGCAGATTCAGCTGACAGTAAGTGAGGATGGGATCGTGACGGTGGTGGAGCCTGGCGGTAAATTAGTAGATAAAGAGGAACTGCATGAAGCTATCAAAATGCCAACAGACCACCAGACGCTTACAGTGCATCAACTGCAACAAATTGTTGGACAACAGGTTTTAGACAGCGTGGTCCGAATAGAGCAGGCTACGGGAGAGCCTGCGAACATCCTCGTCACGCACAACCCTGATGGCACAACATCCATAGAAGCAAGCGCCGGAGAGCAACTTATCGTCAAAGACGAAAAGAGCGCCGCTGGAAAAATAGAAACCGCACAATTCGCCGAAATAAAAGATATGAAAGGAATTGATCTGAAGAGTGTAGGGGCACTGGGCATGGAGGGTGCAGTAGTGAAAATTTCTGGGGGATCCGAGCATGATCTCCACGCCATGTACAAAGTCAATGTGGAAGACTTATCACAACTGCTGGCCTATCATGAAGTATTCGGGAAACTGAATGCTGATGGACAGCCACAAGCAAAGgttatAAGCGAAGTGGAAGTGGAGGCGGGAACCAGTACCGCAATGTCAGCAGAAGAGTCCTCACCGGGCCACCACTCATGCGACATCTGTGGCAAGATATTCCAATTCCGATACCAACTTATTGTCCATAGACGATATCACGGGGAGAGTAAACCATTTACATGTCAAGTTTGTGGTTCCGCCTTTGCCAATCCGGTTGAATTATCAAGACATGGGAAATGTCATCTTGCCGGAGACCCAGCCGAGAGGCACCAGAAGCGGTTGACGCAAGACAAACCGTACGCTTGCACCACTTGCCATAAAACATTCTCGCGGAAGGAGCACCTTGACAACCACGTCCGCAGTCATACTGGGGAGACTCCGTACAGATGTGAGTTCTGCGCCAAGACGTTCACCCGCAAGGAACACATGGTGAACCACGTGCGCAAACACACAGGCGAGACGCCGCACCGCTGCGAGATCTGCAAGAAGAGCTTCACTCGGAAGGAGCACTTCATGAACCACGTTATGTGGCACACTGGTGAAACTCCACACCATTGCCAATTATGCGGCAAGAAGTATACTAGGAAGGAGCATTTATTGAACCATATGAGATCGCACACAAACGATACGGCGTTCCGATGCGAACTGTGCGGCAAGTCGTTCACCAGAAAGGAACACTTCACCAATCACATTTTGTGGCATACCGGCGAAACCCCCCACCGCTGCGACTTCTGTTCCAAAACCTTCACGAGGAAGGAGCACCTTCTAAACCACGTCCGGCAACACACGGGCGAATCCCCGCATCGCTGCAACTTCTGTTCCAAGTCGTTCACGCGACGCGAGCATCTCGTGAACCACGTCCGGCAGCATACCGGCGAAACGCCCTTCCAGTGCGGGTACTGCCCGAAGGCGTTTACGAGGAAGGACCATCTCGTGAACCACGTGCGGCAACACACCGGCGAGTCGCCGCACAAGTGCTCGTTCTGCACGAAGTCGTTCACGCGCAAGGAGCACCTCACGAACCACGTGCGCCAGCACACGGGCGAATCCCCGCACCGCTGCACATTCTGCTCCAAGTCCTTCACGAGGAAGGAACACCTCACCAACCATATACGAATTCATACGGGTGAATCGCCCCATCGCTGCGACTTCTGTCAAAAGACGTTCACGCGCAAGGAACACCTCACGAACCACATGAAGCAACACACGGGCGACAAGCCGCTTGCCTGCAAGGTCTGCTCCAAACCTTTCACGAGGAAAGAGCACCTCGTCACGCATATGAGgTCCCATAGTTGTGGTGAACGGCCGTTCAGCTGTGGCGAGTGTGGAAAGTCGTTCCCCCTGAAAGGAAACTTACTCTTCCACGAGCGATCTCACAATAAGGGTACGGCGGGGGGCAATCGGCAATACCGTTGCGACATTTGCTCCAAGGATTTCTTATGTAAAGgaCATCTAGTAGCACATCGGCGAACGCACACAGACGCAACCGAAAATTCAGGTAGCGTCGAAGCCCCATCAGAGATCGAAGACTGCACAGAGTGTACTAGCAAGTGTGAAAAGAGCGATACCGAGATGCCAGAGAGAAAGCACGAAATAAGGACATCAACTGAGAACAGGCCAACAGAAAACAATGTCTCACAAAGTCAAACTAACGCAGCTGTGATGCAAATAACAAGTCAGGTAAATAGTTGTTcactgtaa
Protein Sequence: MNPEHHSINTGGGQPPGSSESQNQRVQTAQQQQQAANLPATTSATDLRVNSAAVNVALSSVAKYWVFTNLFPGPIPQVSVYGLPTGARIENGKPVQDLGQHASILNGDPNIILGHHGGQPQVTVSASGAQQIPVSQIIATQSGQPHEALVAHNQQQELQQQASGTTQVTVSAGQPNHQQVPNNRVEFVQHHNIDMVNHVGHHSQQHLMQQQLMASARPEHSNQQIQLTVSEDGIVTVVEPGGKLVDKEELHEAIKMPTDHQTLTVHQLQQIVGQQVLDSVVRIEQATGEPANILVTHNPDGTTSIEASAGEQLIVKDEKSAAGKIETAQFAEIKDMKGIDLKSVGALGMEGAVVKISGGSEHDLHAMYKVNVEDLSQLLAYHEVFGKLNADGQPQAKVISEVEVEAGTSTAMSAEESSPGHHSCDICGKIFQFRYQLIVHRRYHGESKPFTCQVCGSAFANPVELSRHGKCHLAGDPAERHQKRLTQDKPYACTTCHKTFSRKEHLDNHVRSHTGETPYRCEFCAKTFTRKEHMVNHVRKHTGETPHRCEICKKSFTRKEHFMNHVMWHTGETPHHCQLCGKKYTRKEHLLNHMRSHTNDTAFRCELCGKSFTRKEHFTNHILWHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCNFCSKSFTRREHLVNHVRQHTGETPFQCGYCPKAFTRKDHLVNHVRQHTGESPHKCSFCTKSFTRKEHLTNHVRQHTGESPHRCTFCSKSFTRKEHLTNHIRIHTGESPHRCDFCQKTFTRKEHLTNHMKQHTGDKPLACKVCSKPFTRKEHLVTHMRSHSCGERPFSCGECGKSFPLKGNLLFHERSHNKGTAGGNRQYRCDICSKDFLCKGHLVAHRRTHTDATENSGSVEAPSEIEDCTECTSKCEKSDTEMPERKHEIRTSTENRPTENNVSQSQTNAAVMQITSQVNSCSL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01252031;
90% Identity: -
80% Identity: -