Basic Information

Gene Symbol
-
Assembly
GCA_959347415.1
Location
OY365768.1:12927782-12932280[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 0.0088 0.82 10.9 1.1 2 23 30 51 29 51 0.96
2 14 0.00025 0.023 15.8 1.7 1 23 89 112 89 112 0.93
3 14 2.8e-05 0.0026 18.7 1.9 1 23 114 136 114 136 0.97
4 14 0.28 26 6.2 0.2 1 23 171 193 171 193 0.91
5 14 0.78 73 4.8 0.2 2 19 223 240 222 242 0.91
6 14 3.2 3e+02 2.8 0.2 5 23 256 274 253 274 0.87
7 14 0.00077 0.071 14.2 0.8 1 20 280 299 280 300 0.94
8 14 0.0053 0.49 11.6 0.6 1 23 312 334 312 335 0.94
9 14 0.84 78 4.7 0.1 3 23 349 371 348 371 0.92
10 14 1.4 1.3e+02 4.0 1.2 3 23 378 398 378 398 0.96
11 14 0.0018 0.17 13.0 1.1 1 23 403 425 403 425 0.96
12 14 0.00048 0.045 14.9 1.0 3 23 433 453 431 453 0.96
13 14 3.5e-06 0.00032 21.6 1.4 1 23 459 481 459 481 0.97
14 14 7.9e-06 0.00074 20.5 1.9 1 23 487 510 487 510 0.98

Sequence Information

Coding Sequence
ATGGCTTCTCACACCCAAACCCAACCTGACAGACCAAGCTCTCATATGAACACTAAACCCACTACAATTGATATAGTTGGCGGTATTTACTGTCATATATGTAACCTGACCTATGCAAATAAGAGAGATTATGATCTACATTACGCTAAACACGAAACTGGCTCAAAGGATATTGTTTACACTTGTGTCGTGTGCCGCAAGGGGATTGCAGGATACCCAAGCTTCCGTGGCCATTGTTACACAAGTCATGTCATCAAAGATAGATTTAAaTGTGATCATTGctctaaattgttttcaaagtTATCATCTCTACGGGAACATGTTGTTGTCATGCACAGATTTAAATGCAGCACCTGTAAAAAAGAatttacatcAAAAAAAGAGCTGAAGCTTCATGAAATAATTCACAATGACAATGATAGCCCACCATACAAATGTCAAGCTTGTAGCACTCAGATAGACACTCTGGAAGGTTGCAAGAATCACATTGATATGCACTCTGCCTTTATTTACTTTTGCCCCATttgcaatgaaaatatatcaaacaagGAAAGTGCTCCAGAACaccttaaaaaacattttggtgATGTCATACACTCAAATACTGTAGAAATACATAAGGGTTTTGAAAAGGAAGAAAGTTCTATACAACATTTAGGTGGCATATCTTGTAGTTATTGCTCCCTGACTTATGAAAACAGAATGGAATTTGATGCTCACTTCTCATGTGAACATGGAGACAAAGATATAATCTATGGGTGCATTGTCTGTGGCAAGCAGTTTGAGAAGTATTCTGTGTTTAGTGACCATGCTTATAATCACTTCACAAAAGACAGGTTTTGTTGCGACATATGTCTGAAGACGTTCAGCCGCCTGTCCCTGCTGGTGTCGCACACGGCGGCGTGCGAGGGCGCTGAGGCCGGTGGCAAGCCCTTCGCGTGCTCGGCGTGCGGCCGGCGGTACGCCTCCCAGCCGCGCCTCAGGGGACACCTGCGGCTGCACCACCCGCCCACCACCAGCGCCACCACCAGCGCGCTCACCGCCTGCGACGAGAGGGGTTGCCTGGAGATATTTGCCACGCCTAAGGAATTGATGTTCCACCAACGTCTTCACCGGTCTGATCAAAACTGGTGTCGTCAGTGCGGGCTCCTGTTTACTTCGCTGGCCTCGTGCGAGCGTCACCTCGACGTCCACAAAAAGAAGTTGTACGTCTGTCCAGTTTGCAACAAAAACTATAGCGAGAAACATCTTATCCTGAAACACGTTTCCCAACACTTCGAAACTGTCTTGCATCTCTGCAAGGTGTGTGGGAAAGTTTACAACGCCAAAAATCGTCTCATAGAGCACATAAAGACTCACTCTGAAACAAAAACGCACAGCTGCACTTACTGCGGAAAAAGCTTTGTAAAAATAGGACAATTGCAACAACATCTGAACGTCCACACCGGCTCGAAGCCATATAAATGTCCGGTGTGCTCCAAATCATTCGCCAGTTATCCCAACTGGCACAAACATTTACGTCGAATGCATAAGAGCGATgggaaaaattataagaaacccGAATCGGAAATGGAAGAGGACTCCAACGACATCGAGAATATTGAAGAATTTCCCATAGACATCGATATACAGAATATAGAGGCACCCGGAGAGGACGACTACACACGCGCCAAGTTACATGTAGAATTAGCAGATATAATAGATACAAAGCTCGATGATTATATGTTTAACGAGCCCAACGATAGCACTATGGAGTCGGACGGCATCGACCCCATCGTGATCGAGAAGGATTTGGGGTCATACGAGGGTGGAGTGGGGGGTGGGGGAAAGGAGGGGGGAGGGGGAGGTGCGGTGCCGGCCGAGTACGGGCCCGAGCTCAGCGGGGTCATCGACCTGGACGACCACATGCTGCCTCACATCGACCCGCGCCTCACCGTCAGCCGCCCGCCCAAGTGGGAGCCCCTCATCACCAAAGTGTACCAGGACTACTCGTACGGCTACGGCGAGATGGACTCCGGCAGGCTGTCCATCGTCAACacagatatattttga
Protein Sequence
MASHTQTQPDRPSSHMNTKPTTIDIVGGIYCHICNLTYANKRDYDLHYAKHETGSKDIVYTCVVCRKGIAGYPSFRGHCYTSHVIKDRFKCDHCSKLFSKLSSLREHVVVMHRFKCSTCKKEFTSKKELKLHEIIHNDNDSPPYKCQACSTQIDTLEGCKNHIDMHSAFIYFCPICNENISNKESAPEHLKKHFGDVIHSNTVEIHKGFEKEESSIQHLGGISCSYCSLTYENRMEFDAHFSCEHGDKDIIYGCIVCGKQFEKYSVFSDHAYNHFTKDRFCCDICLKTFSRLSLLVSHTAACEGAEAGGKPFACSACGRRYASQPRLRGHLRLHHPPTTSATTSALTACDERGCLEIFATPKELMFHQRLHRSDQNWCRQCGLLFTSLASCERHLDVHKKKLYVCPVCNKNYSEKHLILKHVSQHFETVLHLCKVCGKVYNAKNRLIEHIKTHSETKTHSCTYCGKSFVKIGQLQQHLNVHTGSKPYKCPVCSKSFASYPNWHKHLRRMHKSDGKNYKKPESEMEEDSNDIENIEEFPIDIDIQNIEAPGEDDYTRAKLHVELADIIDTKLDDYMFNEPNDSTMESDGIDPIVIEKDLGSYEGGVGGGGKEGGGGGAVPAEYGPELSGVIDLDDHMLPHIDPRLTVSRPPKWEPLITKVYQDYSYGYGEMDSGRLSIVNTDIF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00842998;
90% Identity
iTF_00958883; iTF_00959656;
80% Identity
-