Basic Information

Insect: Mechanitis lysimnia
Gene Symbol: Bcl11b
Assembly: GCA_036026155.1
Location: JAYRBX010000011.1:3179227-3181453[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 2.8 4.2e+02 3.1 1.1 1 23 31 54 31 54 0.93

2 6 1.4e-05 0.0022 19.8 3.3 1 23 319 341 319 341 0.98

3 6 3.3e-06 0.00051 21.8 2.2 1 23 347 369 347 369 0.98

4 6 7.1e-07 0.00011 23.9 3.2 2 23 587 608 586 608 0.97

5 6 9.3e-06 0.0014 20.4 3.3 1 23 614 636 614 636 0.99

6 6 6e-05 0.0092 17.8 0.4 1 22 644 665 644 665 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	2.8	4.2e+02	3.1	1.1	1	23	31	54	31	54	0.93
2	6	1.4e-05	0.0022	19.8	3.3	1	23	319	341	319	341	0.98
3	6	3.3e-06	0.00051	21.8	2.2	1	23	347	369	347	369	0.98
4	6	7.1e-07	0.00011	23.9	3.2	2	23	587	608	586	608	0.97
5	6	9.3e-06	0.0014	20.4	3.3	1	23	614	636	614	636	0.99
6	6	6e-05	0.0092	17.8	0.4	1	22	644	665	644	665	0.97

Sequence Information

Coding Sequence: ATGAATCACCCGGGACACGGAGGGGCTATCAGTCACGGCTGCCGACGTACCGGGCCTGTAGACCTTCTGTTTAACATGCAACCGAGTAACTACGTGTGCTCTACGTGCAAAGCGCGTGTACATTCTGCCTGGCGATTGGTGCAACACGTTCAGCATGTACATGGGGTTAAGATTTATGTGGAGAGCATGCCTCAATTACCGAACAAACAAAACCATTCATCTTCGAGCACTTCATCATCAAGCTCAGGCTGCTCTTCTACTGGCGCTCCTTTACCACCTCCGTCACTACGACATCATCCGCTGCTACCACCACCAGACATGCATTCCCCTTTTGGAGTTGGTGGTTTATTGAGAATGCCATTACCGGGTAGCTTACCCCCTCTAGCTCATCCTTCAGTACCACCGACACCTTTGTTTGCGAGACCGAATCATCATGATCATAGGTTTCGAATGGAACAACTTGTGTCAGAGCAATTTCGTCACCATGGGCTCAACTTGGCAGCAGCGGCTGCCGCTGTGGCAGCAAATTCTCTGCCACCACATCAGGCATTTCCATCTCCAGCCGAAAGACCACCTATAGTTCCAACATCGTTGACGGGACGAGACAGACCACCCGTATCTCAACCCCTCTCACTAGAACCCCAGCTGGATTTTTACTCGCAGCGCTTGCGGCAACTGGCCGGTACGACCAGTCCAGGGGCGGCCACAGGCAATTCGAGCTCTCCTAGCCCCAGGAAGCATTCGCCGCCGTTCGCTTCCCCGTCGCCCTCCCGAGTCGGTCAGACTCCACCGGTGGGCGCCGGACCCGGAACGGTGGACACCCCTCGAGAAGCCATAAGAGCTCACAGTTCAATATCACCCGAAAATCGCATTGAGCCTCAAACAGCTGACGCACCTCCTCCTGAAAGGCCTTCTTCGACGCCACCTGCAAAAAGAAACAACGATGAAGCTATTCACACATGTGAATACTGTGGAAAGAAATTCCGTTTCGAAAATAGCTTAATATCCCATCGACGCATTCATACTGGGGAAAAACGCTTCAAATGCAACCAGTGTGATGCAACTTTTGagaaaaactcaaaattaaaaaagcacATGAAAGCTCATCGGGCAGCTGATGGCAATTCAGAAGAATTAGAATCTGGTGGAGATACTGGCGATGACGATTCGGAAGAAGATTTAGAAGATGAGGAATTAGATGGCGAAGAGGAGGAAGAGAATGAAGACGGTGAGGATGTGGAGGAGGCCGAAGATCTGACCGTATCAAATCATAGTGCTCCTTCAGCTCCCCCTCGAAAACAAACTCCAGCGATTCCAGCTCATCCACCTACCGCTTCAGTTGTGGGTGAACTTATGGATAAGTTCGGTCTGTCGAATATTGCACAATACAGTGAAGCTTTCAAACAAGCTTTACAAGAATCCGGTAACTCGCTAAAATGGCAGTTGGCTAAAGATCGTGATAATAATAACGGTCCTCCTTCTGATAAACCTAATGGTATGCCTCCCACCGCAGCACTAAGATTAAAAGAGGAATTTGCTAAGTTGCCACCTCAGCCACATCCTCTATTTAATCCTTTTGAAAACCCTTTTGAAGCTTCTAAAAGGATGAAACTCGATATGGATAGAGGCGAAGGTTGGTGGCTGCCAACATTACACGCCCAGCGCCCACCGGATAATATATTTGATGGTCTTAAGAATAGTAGTAATGGTTTACTACAAAATCcgttattaaaatcaaaagatGGCCGTCGCAATGATACTTGTGAATTTTGTggaaaagttttcaaaaactGTTCTAATTTGACAGTTCACCGAAGATCCCACACTGGTGAGAAGCCGTACAAATGCGAGTTGTGTTCATACGCTTGTGCACAAAGTTCCAAACTGACCAGGCACATGAAAACCCACGGACGGCTCGGAAAAGACGTGTATCGTTGCAGATTTTGTGAAATGCCTTTCTCTGTGCCATCAACCTTGGAGAAGCATATGCGGAAGTGTGTTGTGAATCAAAGTAATGGTGCTTCTCTTGCTTTATCCGATGACTCTAACGCATGTCGTGATGAGGCTTCGTGA
Protein Sequence: MNHPGHGGAISHGCRRTGPVDLLFNMQPSNYVCSTCKARVHSAWRLVQHVQHVHGVKIYVESMPQLPNKQNHSSSSTSSSSSGCSSTGAPLPPPSLRHHPLLPPPDMHSPFGVGGLLRMPLPGSLPPLAHPSVPPTPLFARPNHHDHRFRMEQLVSEQFRHHGLNLAAAAAAVAANSLPPHQAFPSPAERPPIVPTSLTGRDRPPVSQPLSLEPQLDFYSQRLRQLAGTTSPGAATGNSSSPSPRKHSPPFASPSPSRVGQTPPVGAGPGTVDTPREAIRAHSSISPENRIEPQTADAPPPERPSSTPPAKRNNDEAIHTCEYCGKKFRFENSLISHRRIHTGEKRFKCNQCDATFEKNSKLKKHMKAHRAADGNSEELESGGDTGDDDSEEDLEDEELDGEEEEENEDGEDVEEAEDLTVSNHSAPSAPPRKQTPAIPAHPPTASVVGELMDKFGLSNIAQYSEAFKQALQESGNSLKWQLAKDRDNNNGPPSDKPNGMPPTAALRLKEEFAKLPPQPHPLFNPFENPFEASKRMKLDMDRGEGWWLPTLHAQRPPDNIFDGLKNSSNGLLQNPLLKSKDGRRNDTCEFCGKVFKNCSNLTVHRRSHTGEKPYKCELCSYACAQSSKLTRHMKTHGRLGKDVYRCRFCEMPFSVPSTLEKHMRKCVVNQSNGASLALSDDSNACRDEAS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01080208;
90% Identity: iTF_01080208;
80% Identity: iTF_00959680;