Mlys004722.1
Basic Information
- Insect
- Mechanitis lysimnia
- Gene Symbol
- -
- Assembly
- GCA_036026155.1
- Location
- JAYRBX010000033.1:472774-476058[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 18 2 3.1e+02 3.6 0.1 2 23 12 32 12 32 0.93 2 18 0.0084 1.3 11.1 0.8 2 23 55 76 54 76 0.97 3 18 0.00029 0.044 15.7 0.4 1 23 80 102 80 102 0.95 4 18 0.0029 0.44 12.5 0.5 1 23 107 130 107 130 0.90 5 18 0.00056 0.086 14.8 0.6 1 23 136 159 136 159 0.95 6 18 0.002 0.31 13.0 1.9 1 23 166 189 166 189 0.97 7 18 0.00043 0.066 15.1 1.3 1 23 196 218 196 218 0.98 8 18 0.024 3.7 9.6 0.3 2 21 222 241 221 242 0.93 9 18 0.39 59 5.8 1.4 1 23 326 348 326 348 0.94 10 18 7.5 1.1e+03 1.8 0.0 2 23 372 394 371 394 0.84 11 18 0.0034 0.51 12.3 2.9 3 23 418 438 417 438 0.98 12 18 0.0084 1.3 11.1 3.7 3 23 444 464 443 464 0.97 13 18 0.001 0.16 13.9 2.9 1 23 471 494 471 494 0.98 14 18 3.4e-05 0.0051 18.6 1.7 1 23 500 523 500 523 0.95 15 18 0.0023 0.35 12.9 0.7 1 23 529 552 529 552 0.97 16 18 5.8e-05 0.0088 17.9 0.5 1 23 558 580 558 580 0.98 17 18 9.6e-07 0.00015 23.5 0.6 1 23 586 608 586 608 0.99 18 18 8.4e-05 0.013 17.4 5.3 1 23 614 636 614 637 0.96
Sequence Information
- Coding Sequence
- ATGAATTTGATAAACATGGATATTAGTGAGGCAGTCTGCCGAATTTGTGCCGAACCATTTACAGTCGATGAAATGCGGAAACACGTCATTCAACATGGATATGAGTTTGATTCTGCTCATCCAGACGGTGTTATTCCATTCTGCTTAACAAAAGAATCGTGGACTTGTGTCTTATGTCGTGAGACGTTCAATAATTTTCTGAAACTTTATGAACATATGAATACCCATTACCAGTTTCACATCTGTCCGATTTGCGGTAAAGGCTATATGACTAGACCTCGCCTGAGAAAACATTTAGAATTACATGTAACAGGGACGTTTCCTTGTGATATATGTCAgaaagtatttacaaaacgcACTGGCAGAGAAAATCATAAAGCTTACGCTCACGCTAAAGGTCCACGCTACGAATGTCCTCAATGCAATATGAGATTTAAAGACTATTATGATAGAATGAATCATTTAATGGAGGTTCATAGCGAAAAGGAAGTGAAATACACGTGTTTACATTgtgatttatcttttaaaacaagTGGGAAGAAAGCCGTTCATGTCAAGAAGGTTCATTTTTCTCGACAGAGTGATTTCAGTTGTCTCTATTGCAAAGCTTTATTTAGGACAGCTTTTGATATGAAGAGACACATGATTACGCATAATAGGAAAAGCTGTACTGTTTGTGCAGAAAATTTTACTACAATTAGGGCGTTAAAGAAGCATCTAACAAggTCCTCTAATGCGAATATGGCAGGTATGGTAGTCGTAAAACCGGTTAGAAAGTTAAAGGAAAACGTCTGCGCCAGACAAATGCGCCGGCGACGAAGAGCTAACAACGAGTTTCCAGAAGAATCAGACAAACGAACAGTCAAGAAAGTAATATGGAAACGAAGACGCAGGCCATATAACGATCATAGAGATAACGCGGCTACTATCATTGAGTTTTCTAACGTTTGTCCATTTCGTTGGAAACGGGGTGCTTTCGCTTGCTCGTACTGCCCAAGCACCTTTGGACATTTTACTGAGGTTTATAATCACACTCTGGAACATACTAGTCGACTCGATGCAATGAGATACGCTCGGCCCtatgataacattaaaatagaaatcaGCAATTTAAAATGTGAGATTTGTCAGGACCCAATAGACAAGTTAGAAGATTTAAAGGATCATTTAGTCAACATACATCAGAAGCCTGTCTTGAAGAATTTGGGTCTGGGGGTGACTCCTTTTATATTGCAAGGCAAGGAAATGCTCTGTGCACACTGCAATGAACGTTTCTCcttattttcaaagttaaatagTCATATGAATCAACACTATCcgaataatatatgttttcattgCGGGAAGTCTTTTACAGCTGTACATAGAATGAAGGCTCATCAGCTCACGCATGAATCTAATGATCAGGAGCATAAATGCTCAAAATGTGATGAAGTTTTCGAATCTCGAGCTCTCAAAAACTATCACATGAATACCAAACATACCCCTGTAAATCGATACAGATGTCCCTACtgtaatttatcatttaaacgTTATTCAGACAGGTTGCGTCATTTAAAGGATGTTCATGATCAAAGCGTGGAATATCCTTGTCATTTGTGTACAGCGGTATTTGCAATGTCTGACCAAAGaactaaacatattaaaaacgttCATATAAAGCATAAACAATTCCAATGCGATTTTTGTCCGAGTAAATTCGTTACGGCTGGACAGTTGAAAAATCATATGGTTAAACATACTGGTGTACGAGAATTTCAATGTGGTGTCTGCAAAAAAAGTTACGCTCGAGCTAGGACGTTGAAAGAACATATGCGAATACACAATAATGATAGAAGATTTGAATGCGAGTACTGTAATAATGCTTTTATCCAAAAATGTAGTTTGAAAAGCCATTTACGGACGCACCACCCCAATGCCGAATCAAACAAAACTAGAACAGAGTAG
- Protein Sequence
- MNLINMDISEAVCRICAEPFTVDEMRKHVIQHGYEFDSAHPDGVIPFCLTKESWTCVLCRETFNNFLKLYEHMNTHYQFHICPICGKGYMTRPRLRKHLELHVTGTFPCDICQKVFTKRTGRENHKAYAHAKGPRYECPQCNMRFKDYYDRMNHLMEVHSEKEVKYTCLHCDLSFKTSGKKAVHVKKVHFSRQSDFSCLYCKALFRTAFDMKRHMITHNRKSCTVCAENFTTIRALKKHLTRSSNANMAGMVVVKPVRKLKENVCARQMRRRRRANNEFPEESDKRTVKKVIWKRRRRPYNDHRDNAATIIEFSNVCPFRWKRGAFACSYCPSTFGHFTEVYNHTLEHTSRLDAMRYARPYDNIKIEISNLKCEICQDPIDKLEDLKDHLVNIHQKPVLKNLGLGVTPFILQGKEMLCAHCNERFSLFSKLNSHMNQHYPNNICFHCGKSFTAVHRMKAHQLTHESNDQEHKCSKCDEVFESRALKNYHMNTKHTPVNRYRCPYCNLSFKRYSDRLRHLKDVHDQSVEYPCHLCTAVFAMSDQRTKHIKNVHIKHKQFQCDFCPSKFVTAGQLKNHMVKHTGVREFQCGVCKKSYARARTLKEHMRIHNNDRRFECEYCNNAFIQKCSLKSHLRTHHPNAESNKTRTE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01033932;
- 90% Identity
- -
- 80% Identity
- -