Basic Information

Insect: Mechanitis lysimnia
Gene Symbol: -
Assembly: GCA_036026155.1
Location: JAYRBX010000020.1:2935638-2947886[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 20 7.7e-05 0.012 17.5 2.2 1 23 403 425 403 425 0.97

2 20 0.0086 1.3 11.0 1.9 1 20 431 450 431 453 0.93

3 20 2.1e-05 0.0032 19.2 5.4 1 23 472 494 472 494 0.98

4 20 0.00018 0.027 16.3 4.7 1 23 500 522 500 522 0.99

5 20 3.4e-05 0.0052 18.6 5.3 1 23 528 550 528 550 0.97

6 20 1.1e-05 0.0017 20.2 7.3 1 23 556 578 556 578 0.97

7 20 6.9e-07 0.0001 23.9 2.9 1 23 584 606 584 606 0.97

8 20 9.8e-05 0.015 17.2 6.7 1 23 612 634 612 634 0.97

9 20 4.3e-05 0.0066 18.3 5.4 1 23 640 662 640 662 0.98

10 20 4.7e-07 7.1e-05 24.5 1.9 1 23 668 690 668 690 0.98

11 20 4.8e-05 0.0073 18.1 7.9 1 23 696 718 696 718 0.98

12 20 5.5e-05 0.0084 17.9 5.6 1 23 724 746 724 746 0.97

13 20 7.3e-06 0.0011 20.7 4.3 1 23 752 774 752 774 0.98

14 20 1.8e-05 0.0028 19.4 6.4 1 23 780 802 780 802 0.97

15 20 4.9e-05 0.0074 18.1 6.1 1 23 808 830 808 830 0.97

16 20 2.4e-05 0.0036 19.1 6.1 1 23 836 858 836 858 0.98

17 20 5.4e-05 0.0083 18.0 7.8 1 23 864 886 864 886 0.97

18 20 4.2e-06 0.00064 21.5 4.1 1 23 892 914 892 914 0.96

19 20 0.0007 0.11 14.5 0.3 1 23 921 943 921 943 0.96

20 20 0.014 2.1 10.4 5.5 1 23 953 975 953 975 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	20	7.7e-05	0.012	17.5	2.2	1	23	403	425	403	425	0.97
2	20	0.0086	1.3	11.0	1.9	1	20	431	450	431	453	0.93
3	20	2.1e-05	0.0032	19.2	5.4	1	23	472	494	472	494	0.98
4	20	0.00018	0.027	16.3	4.7	1	23	500	522	500	522	0.99
5	20	3.4e-05	0.0052	18.6	5.3	1	23	528	550	528	550	0.97
6	20	1.1e-05	0.0017	20.2	7.3	1	23	556	578	556	578	0.97
7	20	6.9e-07	0.0001	23.9	2.9	1	23	584	606	584	606	0.97
8	20	9.8e-05	0.015	17.2	6.7	1	23	612	634	612	634	0.97
9	20	4.3e-05	0.0066	18.3	5.4	1	23	640	662	640	662	0.98
10	20	4.7e-07	7.1e-05	24.5	1.9	1	23	668	690	668	690	0.98
11	20	4.8e-05	0.0073	18.1	7.9	1	23	696	718	696	718	0.98
12	20	5.5e-05	0.0084	17.9	5.6	1	23	724	746	724	746	0.97
13	20	7.3e-06	0.0011	20.7	4.3	1	23	752	774	752	774	0.98
14	20	1.8e-05	0.0028	19.4	6.4	1	23	780	802	780	802	0.97
15	20	4.9e-05	0.0074	18.1	6.1	1	23	808	830	808	830	0.97
16	20	2.4e-05	0.0036	19.1	6.1	1	23	836	858	836	858	0.98
17	20	5.4e-05	0.0083	18.0	7.8	1	23	864	886	864	886	0.97
18	20	4.2e-06	0.00064	21.5	4.1	1	23	892	914	892	914	0.96
19	20	0.0007	0.11	14.5	0.3	1	23	921	943	921	943	0.96
20	20	0.014	2.1	10.4	5.5	1	23	953	975	953	975	0.99

Sequence Information

Coding Sequence: ATGAATTCGGATCTTCATAATATCAATACGGGTGGTGGCCAGCCACCAGGCAATTCTGAGTCTCAGACTCAAAGAGTTCAATCATCGCAGCAGCAACCGCAAGCACAATCTAACAATTTAACACCTACAACATCTGCTACAGACTTACGAGTTAATTCAGCGGCTGTAAACGTTGCTTTGTCAAGCGTGGCCAAGTATTGGGTGTTTACCAATTTGTTTCCGGGTCCATTGCCACAGGTTTCTGTGTATGGCGTGCCTACTGGTACAAGAATAGAAAATGGAAAACCAGTACAGGATCTTGGTCAAGCCCATGCTAGTATTCTGAATGGAGACCCAAGTATTATTCTAGGCCATGCAGGACAACCTCAGGTCACTGTATCTGCTGCTGGCCAACAGATTCCTGTCTCACAGATTATTGCTACGCAATCTGCTCAAGGACATGAGTCTCTGGTGGGTCACGGTTCTGGCGAGGCAGGCGGGTCACTAGCGGCTTCCTCGCAGGTACCCAATCGGGTCGAGTTTTTACAACATAACATTGACATGGGTCACCACTCACAGCAGCACCTCATGCAGCAACAACTGATGTCGCGCCCTGACCACGCCAATCAACAGATCCAGCTAACAGTAAGTGAAGATGGAATAGTAACAGTGGTAGAGCCAGGCGGAGGCAAGCTGGTCGATAAGGAGGAACTCCATGAGACTATCAAGATGCCAACTGACCACACTCTCACTGTGCATCAGTTGCAACAAATCGTTGGCCATCATCAGGTCATAGACAGCGTGGTGCGCATCGAGCAGGCGACGGGCGAGCCGGCCAACATCTTGGTGACGCAGAACCCGGACGGCACCACCTCCATCGAGACCAGCGCGGCCGACCCGCTCGCAGTCATCAAGGACGAGAAGAACGCCAAGATGGAGCCAGCTCAGTTCGCGATACCGGCGGAGATCAAGGACATAAAGGGGATCGATTTAAAGAGTGCAATGGGTATGGAAGGTGCGGTCGTAAAGATATCAACCGGCACAGAACACGACTTACATGCAATGTACAAAGTCAATGTAGAGGATTTATCGCAATTACTGGCTTATCATGAAGTGTTTGGGAAATTAAATACTGAAGGACAGCCCCAAGCTAAGGTGATAAGTGAAGTGGAGGTGGAAGCAGGAACAAGTGCGGCGATGTCTGAAGCGGAGTCTTCGCCCGGTCATCACTCTTGTGATATATGCggcaaaatatttcaatttagataTCAACTTATTGTGCACAGGCGTTACCACGGCGAAAGCAAACCACATACGTGCCAAGTTTGTGGATCTTCCTTTGCGAATCCTGTTGAACTGTCTAAGCATGGGAAATGTCACCTTGCTGGAGACCCTGCAGAGCGACAAGCAAAGCGGCTCGCCCAGGACAAGCCGTACGCCTGCTCCACTTGCCACAAGACCTTTTCGCGTAAGGAGCACCTCGACAACCATGTACGCAGTCACACTGGGGAAACTCCGTATAGATGTCAGTTCTGCGCTAAGACGTTCACCCGCAAGGAGCACATGGTGAACCATGTGCGCAAACACACGGGCGAGACGCCGCATCGCTGCGAGATCTGCAAGAAGAGCTTCACGCGCAAGGAGCACTTCATGAACCACGTCATGTGGCACACTGGTGAAACACCGCATCATTGTCAAATTTGCGGCAAGAAGTATACTAGGAAGGAGCATTTAGTGAACCATATGCGATCCCATACGAACGATACCCCCTTCAGATGCGAACTCTGCGGCAAATCATTCACCAGAAAGGAACACTTCACCAATCATATACTGTGGCACACTGGAGAAACCCCGCACCGTTGCGATTTCTGCTCCAAAACCTTCACTCGCAAGGAGCACCTTCTAAATCACGTGCGTCAACATACGGGCGAGTCTCCGCACCGCTGCAACTACTGCGCCAAGTCCTTCACCCGCAGGGAGCATCTCGTCAATCACGTGCGACAACACACGGGCGAGACGCCATTCCAGTGCGGATACTGTCCTAAGGCGTTCACCAGGAAGGATCATCTTGTGAACCACGTCCGGCAACATACAGGAGAATCGCCACATAAATGTTCATTCTGCACCAAGTCGTTCACTCGCAAGGAGCATTTAACCAACCATGTAAGGCAACACACCGGCGAATCACCACATCGCTGTGTCTATTGCGCGAAGTCCTTCACTAGAAAGGAACATCTCACTAATCACGTTAGACAGCATACGGGCGAGACTCCTCACAAGTGCACGTACTGTCCGCGCGCGTTTGCGAGGAAGGAACACCTCAACCAGCACGTGAGGCAGCACGTGGGCGACTCGCCGCACACCTGCTCCTACTGCCAGAAGACCTTCTCCAGGAAAGAGCATCTCGTTACACACGTTCGacaaCACACAGGGGAGACTCCATTTAAGTGCACGTATTGCGCCAAGTCTTTCAGTCGAAAAGAACATCTCACCAACCACGTTCATCTCCACACAGGCGAGACCCCACATAAGTGCGCATTCTGCACGAAGACGTTCTCTAGGAAGGAACACTTGACTAACCATGTTAGaaTCCACACAGGGGAATCCCCACATCGTTGTGAGTTTTGTCAAAAGACGTTCACTCGTAAGGAGCATTTGACAAACCACCTTAAGCAACATACTGGTGATACGCCTCACGCTTGCAAGGTGTGCTCCAAACCATTCACGAGAAAAGAACATCTTGTTACTCATATGAgGTCACACAGTTGCGGCGAGCGACCTTTTAGTTGCGGCGAATGTGGAAAATCTTTTCCCTTAAAGGGTAACCTATTATTCCACGAGCGATCTCACAATAAGAGCAACGCCGCCAACAAACCCTTCCGATGTGAAATATGCTCTAAGGAGTTTATGTGTAAAGGGCATCTAGTAACACACCGGCGAACTCACAATGCTAATGAAGCAGCAACGACCGAGCCCGCACCAGAAGGAGAAGATTGTGGAGATTACAAGTGCGACAAGGAAGCTGATAGACCCGAACGAAAACATGATATTAGaaCATCAGTTGATAATAGAGCTACAGAAACTTCAGTGACAGTAAATCAGCAAACTAATACAACGGTTATGCAAATTACTAGTCAAGAAGTCCGAGCTGGAACAGCGACGAGCACGCAATCCGTTGCCGGTACATTCACGCATACAAGCACCCACCACTCCGGCACGATAGCACAACATCCCGTCACTGTGAATTACTAG
Protein Sequence: MNSDLHNINTGGGQPPGNSESQTQRVQSSQQQPQAQSNNLTPTTSATDLRVNSAAVNVALSSVAKYWVFTNLFPGPLPQVSVYGVPTGTRIENGKPVQDLGQAHASILNGDPSIILGHAGQPQVTVSAAGQQIPVSQIIATQSAQGHESLVGHGSGEAGGSLAASSQVPNRVEFLQHNIDMGHHSQQHLMQQQLMSRPDHANQQIQLTVSEDGIVTVVEPGGGKLVDKEELHETIKMPTDHTLTVHQLQQIVGHHQVIDSVVRIEQATGEPANILVTQNPDGTTSIETSAADPLAVIKDEKNAKMEPAQFAIPAEIKDIKGIDLKSAMGMEGAVVKISTGTEHDLHAMYKVNVEDLSQLLAYHEVFGKLNTEGQPQAKVISEVEVEAGTSAAMSEAESSPGHHSCDICGKIFQFRYQLIVHRRYHGESKPHTCQVCGSSFANPVELSKHGKCHLAGDPAERQAKRLAQDKPYACSTCHKTFSRKEHLDNHVRSHTGETPYRCQFCAKTFTRKEHMVNHVRKHTGETPHRCEICKKSFTRKEHFMNHVMWHTGETPHHCQICGKKYTRKEHLVNHMRSHTNDTPFRCELCGKSFTRKEHFTNHILWHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCNYCAKSFTRREHLVNHVRQHTGETPFQCGYCPKAFTRKDHLVNHVRQHTGESPHKCSFCTKSFTRKEHLTNHVRQHTGESPHRCVYCAKSFTRKEHLTNHVRQHTGETPHKCTYCPRAFARKEHLNQHVRQHVGDSPHTCSYCQKTFSRKEHLVTHVRQHTGETPFKCTYCAKSFSRKEHLTNHVHLHTGETPHKCAFCTKTFSRKEHLTNHVRIHTGESPHRCEFCQKTFTRKEHLTNHLKQHTGDTPHACKVCSKPFTRKEHLVTHMRSHSCGERPFSCGECGKSFPLKGNLLFHERSHNKSNAANKPFRCEICSKEFMCKGHLVTHRRTHNANEAATTEPAPEGEDCGDYKCDKEADRPERKHDIRTSVDNRATETSVTVNQQTNTTVMQITSQEVRAGTATSTQSVAGTFTHTSTHHSGTIAQHPVTVNY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00247403;
90% Identity: iTF_00959562;
80% Identity: iTF_00959562;