Basic Information

Gene Symbol
hang
Assembly
None
Location
GL501434.1:204918-217325[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 25 0.0012 0.099 13.5 0.8 2 23 226 248 226 248 0.95
2 25 0.52 44 5.1 3.6 2 22 321 341 320 341 0.93
3 25 0.34 29 5.7 0.8 3 21 351 369 350 370 0.95
4 25 0.13 11 7.0 0.4 3 23 411 432 409 432 0.92
5 25 0.2 17 6.4 0.4 2 20 445 463 444 465 0.92
6 25 0.56 47 5.0 0.2 3 22 474 493 472 495 0.87
7 25 0.00039 0.032 15.0 0.8 3 23 532 553 530 553 0.95
8 25 0.0017 0.14 13.0 0.2 1 23 561 584 561 584 0.97
9 25 0.27 22 6.1 0.0 1 23 600 623 600 623 0.93
10 25 2.1 1.7e+02 3.3 0.1 1 23 626 648 626 648 0.90
11 25 0.00023 0.019 15.7 0.9 1 23 654 677 654 677 0.97
12 25 3.6e-05 0.003 18.2 0.3 2 23 768 790 767 790 0.97
13 25 0.12 9.7 7.2 3.4 2 23 820 842 819 842 0.94
14 25 0.011 0.94 10.4 0.4 2 23 851 873 850 873 0.95
15 25 9.2e-05 0.0077 17.0 2.0 1 23 912 935 912 935 0.95
16 25 0.0047 0.39 11.6 1.3 2 23 971 992 970 992 0.97
17 25 0.00089 0.074 13.8 1.1 2 23 1001 1023 1000 1023 0.96
18 25 8.8e-05 0.0074 17.0 2.1 2 23 1031 1052 1030 1052 0.97
19 25 0.19 16 6.5 3.8 1 23 1090 1112 1090 1112 0.93
20 25 0.0024 0.2 12.5 0.3 1 23 1160 1182 1160 1182 0.93
21 25 0.003 0.25 12.2 0.1 3 23 1219 1240 1218 1240 0.91
22 25 0.45 37 5.3 0.1 2 23 1264 1285 1263 1285 0.92
23 25 1.2e-05 0.001 19.7 0.4 3 23 1299 1319 1299 1319 0.99
24 25 0.00021 0.017 15.8 0.6 1 23 1437 1459 1437 1459 0.97
25 25 0.078 6.6 7.7 0.9 2 23 1562 1584 1561 1584 0.91

Sequence Information

Coding Sequence
ATGACCGACGATGCGGTGAAACGATTAGTTCGTAGTGGTGGATGTCGATTATGTCTTGCTCCCGATACAGAATGTGTTCCAATTTTTGCGACAGCTGCCGCCGACAAAGAGCCACTTTCGAACAAAATTTTCTCGTGTGTCAACATAAAGATTTTACAGGCGGATCGGATGTCGATTCGAATATGTCATGCATGCATTAGCTTTTTAAATTCATGGCAATCGTTCAAAAATCGATGTCACAATGCCCAAAAGAAACAGCAACAGTTTCTTGATGTAATGATGGCCAAAGAGCGAATAAAACAAAAAACCGATTTAGCACATCAGCCCCAAGAGAACAAGACACCGGACGATTCCAGGCAAAAGATATTAAAGAATGCTTTACTAAATTCAACGTCAAATTCAAACGGAAATAATCTATCGGCAATAGATGTCAGTTACATCAAAGAAGAACCAGAAGAATATGGAAGTGACTCAGATGATATGGATAATGTTGATCCAACACAGTTTTTAGCACAAGACAACGATGACTACTCAAATGCTGAGCACGAGCACCCACAGATTTTAGCATCCCTTGGACTGACACACATAAGTCATCAATACAATGACAACAACAGCACGAATGAAAACCAAAATGATTCGTATGCGGCACAACAGCTTCAACATCGATCCCAGGCCAGTTGTACCATTTGTAATATGCAATTTTCGAACAGAGCAAATGCTCGACGCCACGAACGTAACATTCATAATGTACGTATATTAGTACAGGGCGGTTCAACGATAATCCAACACAAGGATCGTCCAGAAATAGCAATAACAACTCCGTTACGATTAAAGCGGCCACTGGATGTGCCAACGGAATATGATTACACAAATCCCGAACTCTATCGAATACAATTAACCGAACCAAGATTAAATTTCATACGTCGTCACATGGAATTCCTTGAACAATATCAAACTATGACATGCAAATGTTGTAACAAACAATTTCCAACCTATAAATTTTTTATGGCACACATGCGCAAAAAATACGACACATTGTCACGAAATTTATGCTTTAAATGTTTAAAACAATTCCAAACCAAACCACAATTCATTGCCCATTTAAAGAAACGAAATTGTTTGAATTTGTATCGTGTATTTATGGCCGATGAGACCATATCAAAAGAGCCATTACCATCGGCACCATTGCGCCATGGATCGAAGGAAATTTTGGCCAATAAAACGTATGGCTGTCGATTGTGTTCGGAAACTTTTCGATTGAAAAATGATTTTCGCACTCATGTCATTGAGGCACACAGCGATGCACAAAAACGTGAAATTCCGGGCGCAACATCGTGTGGCTATTGTAGTTTGGAATTTGAAGATTCTTCGGAAAGACGTCGTCATTTCAATAATGTTGAATGCATGGTATTCATTATATGTGGTACATGTGATGAACACTTTGATACGCATGCAGCTTATGTTGAACACGTATATGCAATACACATTTCGGCAAATAATGTTGCCAAAACGGAATATTTACTCGATGATGATAATGGTTTGATGGAAGAAGCCATTCCACCGGCCCAATCGAAAGCTCGCAGCCCACAAAATTGTACCGTTTGTGGAAAACAATACAATAATTATTATAATGTATTGCGTCACATGGAATCCAAACATCCGGATCAGGTTCCAACGACATATCGCTGCGATCGATGTGAAATTGGTTATCCGCGCCAGGTTGAATTACGGGATCATATGTTCCGTGTACATAATGAACGCATCAAATTCGATGCAATCAAAATGAAACGTGAACAATTCAGTTGCCGTGAATGTAACGGAGCATTTGATGGTAAAGATGCCTGGATAAATCATCAGGCCGAAGAACATTCCAAATTCAGTTGCAATTTATGCGACGAAGAAACCGAAGACAAGGAAATTTTTTTAACACATTTGATTTTACATTCGGATTCAAAGTCGTACAAATGCCCGGTGTGCCAGCATTCGTTCAGTTCGGAACGTGGTTTTGAAACACATTTGTCGGTTGTGCATAACATGACCAAAGATGAAGTGCAGGATCAATCGAGTGATTTTGGCAGCGAAATGCCAGTCGAATGTGCCGTTGAAATAAATGGCAACGATGATGGAGCTAGCGATTCGGATAATGATATGATGATGATTGATGATGGAAATGATGGAAATGATGGTGATATAGATGAGACGCTCGAGCATCCATTGGTCAAAAGAATAAAAATTGATGAATCGCTCGAAAATTCATCGATCATTTCGAATTCGACCCCTGAAAATGTTTCGCTGAACCTGACGTGTCGCATTTGTAAGGAATCGTTTATATCACGTCCATTGCTCATAACGCACATGCGCACCGCTCATAGTTCGGTCAATAGAACAATACCGACATTAACTGTTGCCGGCGGCAATATGGTGCCAACACAAACGCATAATGTTAACAATCGGCTTCGTTGTCGAATTTGCCAGAAAAGAATTCATACAAAGAATGGATACAAGCGCCATATGTTGCAAATGCATGGTGTCAAGGATTGTGTTTTCATCAAGTGTACTCTTTGCCCATCGGAGTTTAGTAACGACAAAGGATTGAAAGTTCATATGTATAGAACTCATAACATAACCGTCCAGCAAATGCAAGCCGATGAAAGTTTGATTCCAATTCCGAAACAAGAATCCACATCTCCAAGTCCATCACCGATTGTGCCACGGACTGAGGCATCCCAAATGTTTGAATGTAATATTTGTCATACGGTTTATCGAAACCGAGATCAATTAAAATCTCATAAAACCATTGTTCATGGAATTAATGAAGGTGATTTGGATGACGCAGACATTGTTCACGGTGATTTGATGGACTCGATGACAGCAGATAATTCAACATCTGCACCGCAAAATTTTTGGTGGCAATGCAGATTCTGTAAAGAATCATTCAACGCCAATAAAAAGCTATCCATACACATGAATAGTCATGCTGAATACGATAACAAACAAACAAAATGCAAAGATTGTGGCAATGTTTATGGAACAAAAAAATCATTATGGGTTCATCGTCAAAAAAAGCATCCACGCATACCAAATCCATCACCATGTGAATTGTGTGACAAAACGTTCTTTGACAAGACCGAACTATTCCATCACCTGAGTACACATTCAAATGATGCTGTATTCTCGCATTTGCAGGCCATGCAAGAGCAGCTCGAACAAGAACAAGAGCAAGAGAGCCGAGCTAAATTGGAATCAGGGGCTGAAGTTCAGGAAGTTCATGTGTGCATTGAATGCAATCAAAAATTCCATGATAAAAGGGTTTTAAGCAAACATTTGCGTGTCCACGAACAACAAAAACAATCGGAAAATTCGTTCAGCAATTCAGCTTTAGCGGCAATGTTGGCCGACACTGAAATCACAACCGATGAAAATGCAGGCGACTATAGCTATCCAACATATAAAGGACAAAAAGTTGAAAATGGTGAATTTGCGTGTGATATGTGCCCGAAACGATTCCCTCATGTAAATGCATTGAAAGTGCATCGTGGATGGCATTTCCGATCACCGGACGGTCGACAGATTACCGATAGCAATAGCATTTGGCGTCCGGATGTTGGAAATCACAGCCGAAATAAACGTTCTCGTGCAGCGAATCCACCGATTTGTCCCTATTGCAAATCCACTTTTGCTTCTGGCAATAATTTACGTCGCCACATTGTCGAAGTTCATAAACGAAACGAAGCCAAATTGGCTCGTGAAAATGGGGGCGGCGATGAAACATTTATCGAAAAAGAACTTGAATGCATGGCATGTGATTTGACATTTAGCAGCCGACCCGAATGGATTGATCATAAAATAAACCATGCGCGAACGATGAAACCATCAACCACATATGAATGGGGCTGCGAAATTTGTGGAAAAGTATTCACACGAAAGGAAAGACTTTTGGTTCATATGACATCACATATGTCTGGCAAGGAAGAAGATATTAATCAAAAACGAGCTGAAATGGGCTTCGAAAGCAATTCACAAAGTTCAATGTCATCGCATTCGCATTCACAATCACAATCACAACAAATGCTCTCACAACATTCGCTCGATTCGGCTACTCTTCGGAATGCCTTACAAAAGACCACATCTGATTCAAAATCGGCAAGCAATTCTTTGCTAAAGCAACAGCAATCTTTGTTAAAATCCGCTGTTCAGTCGAGTAATTCAAGCCAAGCCATCGAAACAAAAACAAATGATTCAAATGAGTCCATTGAAGACGATATGGATGATGAGAATTCAAATGAGCCAACCGGTGACGAACAGACACATCCATGCGATTTGTGCCAAGCCATTTTTGCAACGAACAAAGAATTGCGTCAGCACATCAAGAGTCATTTTGAGGGCGAAGGTCTCGGTCAGAATGTCGTCGAAACCGAATCGAATGCTGATGATTCTCAATATGATGACGAAGAAGATGATGAAAATGAGGACATGGATGGGAATATAATTGAAGAAGATTACGATGAAGAATTAGGCGAGGAGGAAGACGACTACAATGATGAAGAGATGGCTGAGCAAAATTCGAATGCAGTACATCGAATGCAAATAACGGGTTACAATTGCCGAATTTGTGGTTCAAGCAGTCAATCTCATATTGATATGCTGAGTTGCATGAAAAGCCATGAAAAACCAACACGAATCGAGTGCGAAGAATGCTCTTTTTATTTTGTAGATTTTGAGCAATTGGAAAAGCATGAATCGCTATGCCATCCCAAGGAGGAATACGATGACAGTGACTGA
Protein Sequence
MTDDAVKRLVRSGGCRLCLAPDTECVPIFATAAADKEPLSNKIFSCVNIKILQADRMSIRICHACISFLNSWQSFKNRCHNAQKKQQQFLDVMMAKERIKQKTDLAHQPQENKTPDDSRQKILKNALLNSTSNSNGNNLSAIDVSYIKEEPEEYGSDSDDMDNVDPTQFLAQDNDDYSNAEHEHPQILASLGLTHISHQYNDNNSTNENQNDSYAAQQLQHRSQASCTICNMQFSNRANARRHERNIHNVRILVQGGSTIIQHKDRPEIAITTPLRLKRPLDVPTEYDYTNPELYRIQLTEPRLNFIRRHMEFLEQYQTMTCKCCNKQFPTYKFFMAHMRKKYDTLSRNLCFKCLKQFQTKPQFIAHLKKRNCLNLYRVFMADETISKEPLPSAPLRHGSKEILANKTYGCRLCSETFRLKNDFRTHVIEAHSDAQKREIPGATSCGYCSLEFEDSSERRRHFNNVECMVFIICGTCDEHFDTHAAYVEHVYAIHISANNVAKTEYLLDDDNGLMEEAIPPAQSKARSPQNCTVCGKQYNNYYNVLRHMESKHPDQVPTTYRCDRCEIGYPRQVELRDHMFRVHNERIKFDAIKMKREQFSCRECNGAFDGKDAWINHQAEEHSKFSCNLCDEETEDKEIFLTHLILHSDSKSYKCPVCQHSFSSERGFETHLSVVHNMTKDEVQDQSSDFGSEMPVECAVEINGNDDGASDSDNDMMMIDDGNDGNDGDIDETLEHPLVKRIKIDESLENSSIISNSTPENVSLNLTCRICKESFISRPLLITHMRTAHSSVNRTIPTLTVAGGNMVPTQTHNVNNRLRCRICQKRIHTKNGYKRHMLQMHGVKDCVFIKCTLCPSEFSNDKGLKVHMYRTHNITVQQMQADESLIPIPKQESTSPSPSPIVPRTEASQMFECNICHTVYRNRDQLKSHKTIVHGINEGDLDDADIVHGDLMDSMTADNSTSAPQNFWWQCRFCKESFNANKKLSIHMNSHAEYDNKQTKCKDCGNVYGTKKSLWVHRQKKHPRIPNPSPCELCDKTFFDKTELFHHLSTHSNDAVFSHLQAMQEQLEQEQEQESRAKLESGAEVQEVHVCIECNQKFHDKRVLSKHLRVHEQQKQSENSFSNSALAAMLADTEITTDENAGDYSYPTYKGQKVENGEFACDMCPKRFPHVNALKVHRGWHFRSPDGRQITDSNSIWRPDVGNHSRNKRSRAANPPICPYCKSTFASGNNLRRHIVEVHKRNEAKLARENGGGDETFIEKELECMACDLTFSSRPEWIDHKINHARTMKPSTTYEWGCEICGKVFTRKERLLVHMTSHMSGKEEDINQKRAEMGFESNSQSSMSSHSHSQSQSQQMLSQHSLDSATLRNALQKTTSDSKSASNSLLKQQQSLLKSAVQSSNSSQAIETKTNDSNESIEDDMDDENSNEPTGDEQTHPCDLCQAIFATNKELRQHIKSHFEGEGLGQNVVETESNADDSQYDDEEDDENEDMDGNIIEEDYDEELGEEEDDYNDEEMAEQNSNAVHRMQITGYNCRICGSSSQSHIDMLSCMKSHEKPTRIECEECSFYFVDFEQLEKHESLCHPKEEYDDSD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-