Basic Information

Gene Symbol
-
Assembly
GCA_030765055.1
Location
CM060947.1:70667913-70715781[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.16 69 6.5 2.9 2 23 176 197 175 197 0.96
2 16 0.029 13 8.8 3.3 2 21 211 230 210 231 0.94
3 16 5.7 2.5e+03 1.6 0.3 2 23 443 464 442 464 0.85
4 16 7.3 3.2e+03 1.2 0.3 13 23 595 605 594 605 0.89
5 16 0.037 16 8.4 2.7 1 23 648 670 648 670 0.96
6 16 0.0077 3.4 10.6 5.3 1 23 677 699 677 699 0.99
7 16 0.22 99 6.0 1.3 1 23 768 790 768 790 0.98
8 16 0.014 6.3 9.7 1.1 1 23 812 834 812 834 0.97
9 16 2.8 1.3e+03 2.5 4.8 1 23 915 937 915 937 0.95
10 16 0.002 0.89 12.4 1.1 1 23 943 965 943 965 0.99
11 16 0.015 6.9 9.6 1.7 1 23 1036 1058 1036 1058 0.97
12 16 0.0019 0.85 12.5 1.1 1 23 1064 1086 1064 1086 0.97
13 16 0.0034 1.5 11.7 2.6 1 23 1169 1191 1169 1191 0.97
14 16 5.8e-05 0.026 17.3 2.0 1 23 1197 1219 1197 1219 0.99
15 16 0.00036 0.16 14.8 0.7 1 23 1315 1337 1315 1337 0.98
16 16 0.056 25 7.9 3.5 1 23 1347 1369 1347 1369 0.96

Sequence Information

Coding Sequence
ATGGCTCGTCATGAAAGCAAAGCACATGGCATTGGGAGACCCAAACCTATAGTTTCACATACAAAGAAGATTCCTCGACCTATCCCAAACCTTATACCCATACAGAACAAAGGAGTGAACTCTAACAATTCAAATCTTCCTATCTTGCGCATTCCTTCTGTTCGTAGTCGTGCTCCAAATTCAGTATTAAAACCATCAACTCCACCAGAAAACAGCCTCAGTGAGCAAGACCTAAATGAAATATGTGCCAAGTCATGTCCCAATAGCTCCTTGAAGGATTTTGCATCACTAATAGGAGGAGAAGAAATATTTAGGACTACTGATGAAGATCTCAATGAGCTaacaaatactgaaactacagAAAAGGCTTCTCCAGTTAAAGAAGAGGAAACTGCTGCTTCAGAAGAGACTACACTTAAACCTGCATCACCACCGCCAACAGaagtttttaaaaagaaaaatgcttCATTCTTTGATAAGTTGAAAGAGAAACTGCTTGTTGGTGCAGGTGAGAGTTGCAATCTTGTGTGTACATATTGTGGACATGAATCAAAGTGCCTCTCAGAACTGGCTCGTCATCAAAAACTGCATATAGGACCAGCTGGTAGATCTCTTACATTATCCTCCACACGGTGTCAGCATTGTCGTCAGCGATGTAAAACTAGTGCAGATCTCATGGTTCATTTAAAGTCATGTTCAGAAGCTAACAAAAGTGTAGCATCTACAGAACcaccagaggaagaggaagaagaagatggaGAACAGGAGAGCAAGGATGATGTGCAggaaaccaacaaatacaaaatggCATTGGAAGAAcctgaaggagaagaggaagaagaaggtgAACTAAAATCAAATTTAGAAGATGAACCTCATCCTATGGAAAACAAAGTTTTTGTATGGAATAATCTCCCAGAAGAACATGGTTCCCCAGATGAGGATCACAGTAGTGAAGGTAGTCTTGTTGGTGTTGAAACTGCTCCAGGTTATGGggctgtaacaaacaagacgccATCTGATGCTGTAGAAGTGGCTCCTCCAGAAGTGGACCCCAAAGTTGCTCTGACTGTAAAGAAGGTAATGCAGCTGCCTGCCCCTCCACGACTTACTCGAGCTCCTACTCCTGCTCCAAGTACCACACCACCATCAACTGGGCCTCTGCGTCCCCCACCACCATTACGAGCTGCACATCAGGTTGTGTTTCCAGGACCGCCACCTCTACATCCTCAGCCACAAGTAACAAAGAAGAGATCAGCAACAGATGAATCAGAAAATCAGCCTCaaccaaagaaaccaaataatgaTGGCAAGAAAACATTGTGGAAATGCAAAAAGTGTAATTATAGGGATGCTAGCAGAGAACTTGTGTTGGCCCATGTGAAAGAGCATTATCAACAGCgtcagcaacaacagcagcagcaacagcagctgCAGCAGCAGTTACATCAACAGGATACCCaggaggagcagcagcagcatttACCTCAGTCTGACGAacttgatggtgatgatgaggcAAGTGTCAATTGGGGACAGGCACCATTCCGGTGTGGCCACTGTCTCCAGATGACAGGAATGAAGAAGACAAGTTATGCAGATGTCATAACAATTGGGCAACAGCTACTGGAATCTGTGCACCTGCCAGAGTATTTGGTTCGTGCTCAACCTTCTTCAAGCACAACCCCTTTGAGACTACAGGCAAAATCATGGGCTCACATCCCTATGCACATTCCCTCAACTGAAAAGAAAAGTGACCAAAAGGTGTGTCGTGTGCTACAGCAGGGaGATCTACTCCAGCACATGAGGCTACATGGTGTCAATGAACCAGAAGATTACATATCAAAAGCTTTGAGTGGAACAAAATCACCAACAAAGACTGAGAAATCTGAAGAGGGTGGACGACAACATCACAACATTGAAACAAGTCCACACAAACGGTACAAGTGTTTTGGTTGCCCATATGTGAGCAACAGCAAGAGTCAGTTCCTATACCACAAGCAGTTTCATCGGCCACGTACATCACAATTCAAATGTAGCCTCTGCTCCTATAATGTCAGCCGGAGACATCTTCTACACCAGCATTTACGCGTTCATGGCATCCTTGTACCTCCTCAAAAAAGTCCTTCCAAATCTGGTATGGGTACTGACGATGGTGATGGCACTGATATAGAAGAAATAACGGAGCTTCCTTCTCTCATGTCATCCTTCTCGCAGAACACAATCCCAGCACTTGATACGCGTCAACTGCCTGATATTCCTTTAGTTTGGGTTTGCCGATCTGGCAacttttgcaagatgttcaaGTGCCGTTATTGCCCACATGTTAATGCCCGCAAGGCTAACATACAAGAACATGAAAAAATGCATCGTGCGCGAGATACTGACCACTCAACTGGTGATGGTCATAAAGAAGGCACTCAGCAACAACAGTTTCACTGTCCAGATTGTAATTACATATGCAACAATGCAGGGGTTCTTTCGTCACATGCCAAAGTCCATCAGGGGTTATATGGTCAGGTGCACTGCCTTGTGGATACTACTCGCAGTGATGAAGTCCAATTGCGAGAACTGAATGCAAGTATAAACCGAGAGGAAAATGATGATGAAATGGAAATCCGTGAGGCAGAAGAAGAAACAATGGACTTTCAGTTAGAAAATCCAGCAGAATCTAGTCCACCAAGAAGTACAGCTGAAGAAAGTGAAGTTAAGAATATTAACATGGAAGAGAGGAAAATTCTTCACTTCTGCAAACACTGCCCTGCAAGGTTTCTCTTTGAGAAAGAGCTGAATATCCACACTCGTTTCCATGAGATTCGATTGGCTTATAGATGTGATAGCTGCTCTTACACTGCAAGACAAAGACCACATCTTCTTGCTCATCTCCGAGTGCATACTGATGAGTATCAGCAGCGCACCAACAGCCTTGTTGATGCTTATTCTGTATCTTCAGTGCATCCACGGCCAAAAACTGCTGTTGTAATTGAAGGTCCTGGAGTCATAGGATCTGTATGGGTTGTTATTGGTAAGAGTCCTGAAGCAGATAAATCATCTTTGAGTGCAGAAGTGACATCAACATCTACTGGTCGACCTGTTGTGAAGCAGTATTCCTGTCATCTGTGTCCAGCAAAGTTTTTCAAAAGCATGGCGTTGCAGTACCACATAACTCTTCATGGTGGTTCAGGACCACATAAATGTCGACAGTGTGACTATGCTGTCAAGACGTATGGAAATCTTGTAAAGCATGAAATGATACATAAAAGTTCATCTCCAGAAAAGAAGCCAAAATCTAGTACTGGTCCAAATTTGAATACTATTCCTCTTTCAGGAACAGAGCTTTTCCAACACCGAACAGAAGCGCAGAAACAAAGCTTGGCTGAAAAGAAAACTCCTAGTGAACCTCTGCCATTGCATGTTGATCCACAATTTGGCATCTTAATGCATGGAAATCCAGATTTTATTTATCCTACTTACTTCAAAAATGGTCGCTTAAAAGAGAAACGTTACAAATGTCACAAATGTCCCTCAGCCTTTGAGAAACGTGAGCAGTATAAAGTACATCTTTCATTGCATGGGTCAAGGCAGCGCTACAGATGTGAAAAATGTGATTATTCAGTCAAATATTATGCAAACTACATACAGCATATGAGAAAACATAAGAATAATGAGGAAGCACAAGAAGCAAGGAAGCTGGAAAAAGGTGACAAGGATGAAACTCAAGAAACCAAAGAGGATGATGAAGCTGCAGAGGATTCAAGTATAATAGATGATGAACCAATTGTACCATCTACCAGAACTGTAAAGACAATTGGTAGTACCCATCATGGACCTTTGCAACTTTCTACAGCTGACCAGCAAACTTTAATCTTAATGCAAAAACGGCAAGAAAATGTAAATTCTGGTGGATTACAGGATGGCACTACTTCAGAGGAACGTCGGTCATTCCGCTGTCCACACTGTCCATATACAAGCCCCCGTCGTGATGGGGTAGAATCACATATCAAAAGGCATCTGGTTGTGTCAGGAGTTCGTGGTGCATTTGTTTGCACCCATTGTGACTACACAGTCCCGCAATTACATTTTTTGCGTGAACATAACAAATTACACTTTAATCACTCTAAAAAACTTCAACCTGACATTTACATGAAATTTGAACGTCTTGAATTGTGGGTGACAGATGAGGGTAAAGAAAACATGACAGCCAATGTATCCTTGGAGTCAAATGGAGGAAAGCGCTTACTTTTCAAGGATAGTGGTACAGAGGTAGAATGTGATGAACGATTTATTCCACCACTTTCACCAGTAGAAGAGGTACCAGAGGAAGAAAAAATATATGTAGATCCACGTACAggtgaaaaaattagtagtgttAAACCTGAACCTTCACGTGTTGAGCACGGAGACGACAGTAAACAGTTACCTAAAAGGGAGAACATGGATGATAAAGAGTGTGCAGCAGAAGCGGctgcagaagcagcagcagaagcagcagcagtagcggcagcagaagcagcagcagaagataCCAAGTCTGAATCTGgaagtactagcagtagtactaCAAGCTCAAGCAGCAGTAGTTCAAGCAGCAGttccagcagtagtagcagtaacagCAGTGGTACCAACTCTAGCAGCAACTCCAGCTCAAGTAGTGGTAGCACTACCACAAGTACAAGTGGAGAAAGTGACTCTGAAAGTGAAGGGGCTCCAGCAGTGGTTGATGATGCCTCATCAACATGTTCAATGAATTAA
Protein Sequence
MARHESKAHGIGRPKPIVSHTKKIPRPIPNLIPIQNKGVNSNNSNLPILRIPSVRSRAPNSVLKPSTPPENSLSEQDLNEICAKSCPNSSLKDFASLIGGEEIFRTTDEDLNELTNTETTEKASPVKEEETAASEETTLKPASPPPTEVFKKKNASFFDKLKEKLLVGAGESCNLVCTYCGHESKCLSELARHQKLHIGPAGRSLTLSSTRCQHCRQRCKTSADLMVHLKSCSEANKSVASTEPPEEEEEEDGEQESKDDVQETNKYKMALEEPEGEEEEEGELKSNLEDEPHPMENKVFVWNNLPEEHGSPDEDHSSEGSLVGVETAPGYGAVTNKTPSDAVEVAPPEVDPKVALTVKKVMQLPAPPRLTRAPTPAPSTTPPSTGPLRPPPPLRAAHQVVFPGPPPLHPQPQVTKKRSATDESENQPQPKKPNNDGKKTLWKCKKCNYRDASRELVLAHVKEHYQQRQQQQQQQQQLQQQLHQQDTQEEQQQHLPQSDELDGDDEASVNWGQAPFRCGHCLQMTGMKKTSYADVITIGQQLLESVHLPEYLVRAQPSSSTTPLRLQAKSWAHIPMHIPSTEKKSDQKVCRVLQQGDLLQHMRLHGVNEPEDYISKALSGTKSPTKTEKSEEGGRQHHNIETSPHKRYKCFGCPYVSNSKSQFLYHKQFHRPRTSQFKCSLCSYNVSRRHLLHQHLRVHGILVPPQKSPSKSGMGTDDGDGTDIEEITELPSLMSSFSQNTIPALDTRQLPDIPLVWVCRSGNFCKMFKCRYCPHVNARKANIQEHEKMHRARDTDHSTGDGHKEGTQQQQFHCPDCNYICNNAGVLSSHAKVHQGLYGQVHCLVDTTRSDEVQLRELNASINREENDDEMEIREAEEETMDFQLENPAESSPPRSTAEESEVKNINMEERKILHFCKHCPARFLFEKELNIHTRFHEIRLAYRCDSCSYTARQRPHLLAHLRVHTDEYQQRTNSLVDAYSVSSVHPRPKTAVVIEGPGVIGSVWVVIGKSPEADKSSLSAEVTSTSTGRPVVKQYSCHLCPAKFFKSMALQYHITLHGGSGPHKCRQCDYAVKTYGNLVKHEMIHKSSSPEKKPKSSTGPNLNTIPLSGTELFQHRTEAQKQSLAEKKTPSEPLPLHVDPQFGILMHGNPDFIYPTYFKNGRLKEKRYKCHKCPSAFEKREQYKVHLSLHGSRQRYRCEKCDYSVKYYANYIQHMRKHKNNEEAQEARKLEKGDKDETQETKEDDEAAEDSSIIDDEPIVPSTRTVKTIGSTHHGPLQLSTADQQTLILMQKRQENVNSGGLQDGTTSEERRSFRCPHCPYTSPRRDGVESHIKRHLVVSGVRGAFVCTHCDYTVPQLHFLREHNKLHFNHSKKLQPDIYMKFERLELWVTDEGKENMTANVSLESNGGKRLLFKDSGTEVECDERFIPPLSPVEEVPEEEKIYVDPRTGEKISSVKPEPSRVEHGDDSKQLPKRENMDDKECAAEAAAEAAAEAAAVAAAEAAAEDTKSESGSTSSSTTSSSSSSSSSSSSSSSSNSSGTNSSSNSSSSSGSTTTSTSGESDSESEGAPAVVDDASSTCSMN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00435087;
90% Identity
-
80% Identity
-