Mjur007086.1
Basic Information
- Insect
- Maniola jurtina
- Gene Symbol
- ZEB2
- Assembly
- GCA_905333055.1
- Location
- HG995233.1:6917761-6921926[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 8 0.043 2 9.4 2.8 2 21 265 284 264 285 0.95 2 8 1.8 83 4.3 0.2 3 20 346 365 345 368 0.76 3 8 0.27 12 6.9 1.1 2 21 372 391 371 392 0.93 4 8 0.00019 0.0087 16.8 1.5 2 23 431 453 430 453 0.96 5 8 0.0013 0.062 14.1 1.0 1 23 486 508 486 508 0.98 6 8 0.001 0.046 14.6 0.6 1 23 514 537 514 537 0.97 7 8 0.00023 0.011 16.6 1.6 1 23 546 569 546 569 0.95 8 8 0.0015 0.07 14.0 4.6 1 23 580 602 580 602 0.98
Sequence Information
- Coding Sequence
- ATGAGTAGGCAGGTTGATGTAAAGGCTTTAGTATCGCACGTTATACGAGGAGATGGGGTTAACAAATGCCGAATTTGCATGGGGGACACTTCAGAAGGACAAGTACGATTAAGTGATACAGTTATTATGGAAGGCGATAAACCTGTTACATTATCTCAACTGCTCGAGATCGTAACTGGAATTCAGGTGCCGCTGGACGGTGACCTGCCAGCTGGACTGTGCACGGAATGCTGCACGAGTGCTGTAAATGCTGCTAACTTCAGATCCATGTGCAGGGAAACCTCCTCGAAATGGGACACGATGTTGCAACTCTTGTGCGACCTACCCTCACAGTACTCGGAAAAGGACCAGATTATGTTCGTCATATTGGACGATAGTCAAATGATTGTTGTCATTGATGAAAATTATTTGAATTTAAACACAGTATCTGAGAGATTAGGGGCACATTTGCCGTCACAGGTGGATTCTATCTCCCCAATGGACACAAAAAGCGTTACCGAAGAAAAAAGTGACGTAGACCATGATGGACTAAATACAAAAGGAAATGAACTTAGTGATATCAAAAATGAAAAACCAGAAAGTGAACTTAGAGATATAGAAAACGAAAGTCTAGTCGCAAAAAGAGTGAAAAGAGTAGAAAGTGAACTTATAGATGGTAAAAATGAAAGTCCAGTTGCAAAAAGAGTGAAAAGAGACAAAGTAGACATTAATAAGAGACTAATGACAAATAGAGAAGAAAGTGTACGAAAAGAAGTGGCTAAAAATAGAAGAAATCTACCTATACAAACGTCGCAATGTCCGAATTGCAGCAAAAACTTTCATCATCCGCTGAAACTATATCACCATTTAAGAGGATCGATTGATATGATACGAGCTTGTTATGTATGCAGCGAGATTATGCAACGTGATGAACTTGTCTCACATCTTGATTTAGCCCATAACATAGAAGTTTACGATTGCAAAAAATGCCCTGCCATACTTCTAACAAATAATAAATATATCGAGCATTTAAACGGAGCACATTCACGCGGTGCGTGCTCTTGTATAGACTGCGGACGGACGTTTCAGTCAGACCAAGCGGTTTACGCGCACATACCTGTACACAGACGAAAAACATGTCCGTCTTGCGACAGAATATTCCAAAACCAACCCTGCTACTTGTATCATATAAAGAACTGTTGCAATTTAAACAAAAATTTAAAAAAATCAGAAAAGAGGGTAGTCATCAAAAACGTGAACAGTAAAAAGAACGTTCGAGTCGGTGTACGTGGTGGCACAGATCATGTATGCATCTGTGATTATTGTGGTAGAAGTTTCTTAAAAAAAAAGTACCTGGCGGCGCATATGCAAACTGTTCATATGAAAAACACTCATGCACCTTGCGCGTACTGTGGGAAGCTCCTAGCGACGGTGCATATGACAGAACATCTAAAGCGACACGAGTTAGACTTGTCGTTTAAGTGTGAACACTGTGGAATCGTCCTTAAGACCAAACTCGGTTATGTCCAGCATTTAAGATTGCATACAGGGGAACGTCCATATGCTTGCAAGATTTGTAACGAAAGTTTTAGTGCTTCGTCCAGACGCTCGGAGCATATGCGTAAAGTACACCAAAATACGAGTGTAATACTAAAGCATGCATGCAAGCTATGCCCTGCCAAATTCCGACTGCCGTACAAGCTAAAAAAGCACATGAAATCAGCACATTTAAATGATAGTTATGCAGAAACACAACAGTTTGAATGTCCTCAATGCCACGAAAAGTTTGACTCACGCCGTGGGTTGTTACACCATAGCAGGAAGCATCAAAAAGTGAATTTCCCATATAAGAGACCTGAGAAAACTATTATGTTGAAGGTGTTTAGTGAACCAGACTGTGTTGAGGAAAATCAGTAA
- Protein Sequence
- MSRQVDVKALVSHVIRGDGVNKCRICMGDTSEGQVRLSDTVIMEGDKPVTLSQLLEIVTGIQVPLDGDLPAGLCTECCTSAVNAANFRSMCRETSSKWDTMLQLLCDLPSQYSEKDQIMFVILDDSQMIVVIDENYLNLNTVSERLGAHLPSQVDSISPMDTKSVTEEKSDVDHDGLNTKGNELSDIKNEKPESELRDIENESLVAKRVKRVESELIDGKNESPVAKRVKRDKVDINKRLMTNREESVRKEVAKNRRNLPIQTSQCPNCSKNFHHPLKLYHHLRGSIDMIRACYVCSEIMQRDELVSHLDLAHNIEVYDCKKCPAILLTNNKYIEHLNGAHSRGACSCIDCGRTFQSDQAVYAHIPVHRRKTCPSCDRIFQNQPCYLYHIKNCCNLNKNLKKSEKRVVIKNVNSKKNVRVGVRGGTDHVCICDYCGRSFLKKKYLAAHMQTVHMKNTHAPCAYCGKLLATVHMTEHLKRHELDLSFKCEHCGIVLKTKLGYVQHLRLHTGERPYACKICNESFSASSRRSEHMRKVHQNTSVILKHACKLCPAKFRLPYKLKKHMKSAHLNDSYAETQQFECPQCHEKFDSRRGLLHHSRKHQKVNFPYKRPEKTIMLKVFSEPDCVEENQ
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -