Basic Information

Insect: Maniola jurtina
Gene Symbol: ZBTB8B
Assembly: GCA_905333055.1
Location: HG995236.1:268963-281756[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.0014 0.065 14.1 4.8 1 23 275 297 275 297 0.98

2 11 0.9 41 5.3 0.7 1 23 304 326 304 326 0.96

3 11 0.54 25 6.0 0.2 1 23 330 353 330 353 0.95

4 11 1.8 84 4.3 6.8 1 23 360 382 360 383 0.94

5 11 6.1e-07 2.8e-05 24.7 0.1 2 23 390 411 389 411 0.97

6 11 2e-05 0.00093 19.9 3.1 1 23 417 439 417 439 0.98

7 11 0.0012 0.057 14.3 2.6 1 22 445 466 445 470 0.93

8 11 2e-05 0.00092 19.9 0.0 2 23 479 501 478 501 0.96

9 11 0.0018 0.083 13.8 0.2 1 23 507 530 507 530 0.95

10 11 5.8e-06 0.00027 21.6 4.7 1 23 539 561 539 561 0.98

11 11 0.0001 0.0048 17.6 0.1 1 23 567 590 567 590 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.0014	0.065	14.1	4.8	1	23	275	297	275	297	0.98
2	11	0.9	41	5.3	0.7	1	23	304	326	304	326	0.96
3	11	0.54	25	6.0	0.2	1	23	330	353	330	353	0.95
4	11	1.8	84	4.3	6.8	1	23	360	382	360	383	0.94
5	11	6.1e-07	2.8e-05	24.7	0.1	2	23	390	411	389	411	0.97
6	11	2e-05	0.00093	19.9	3.1	1	23	417	439	417	439	0.98
7	11	0.0012	0.057	14.3	2.6	1	22	445	466	445	470	0.93
8	11	2e-05	0.00092	19.9	0.0	2	23	479	501	478	501	0.96
9	11	0.0018	0.083	13.8	0.2	1	23	507	530	507	530	0.95
10	11	5.8e-06	0.00027	21.6	4.7	1	23	539	561	539	561	0.98
11	11	0.0001	0.0048	17.6	0.1	1	23	567	590	567	590	0.95

Sequence Information

Coding Sequence: ATGGACAAAATCTCTGAAAACTATGAAAGCGAGCTCAAACCTGACTTGGAGTGTGGAAAAGCGATATGCCGATGTTGTCTTACCACCGACAAACGTCTGACGAGGATCGATCTCTTTCGAAGTCTTTTTATCGATTTAGCTGATATTGTGGTAACAGAGTCGGATGGTCTGCCACAGTGGATTTGCTGGGAGTGCAGCGCCTTGCTGCTCAAGAGTGTCAAGTTCAAGCACAAGGTGCTCCGAGCACACGCCATGCTGTATGACTATCATAGGAGATGTGCACCTTTCCCAATAGATGGTGCGGATCCTGAACTCACAAAATACGCAAGCCCACACCTAAGTACCTGTACCACCCTCGTTTTTGACACTGGAAAAGAAAAAAAAATTGGTTATCATCAAGTTTTAGAGCACGAAAAATCTATAGTCAAGTCCCAACTAGATGACATTTTAATAGTAGAAGCGGATGACACAAACTTTTATGATGACCAAATATCAGTTAAGGATGAAGCAATGTTGTCAGACTGTGACGACAATGTTCCTTTGCATGAAATTAGATCAAATAAAAATGAATGTGAAGGGCAATTATTACCTAAAACGGAGATAAAAGAAGAGAAGAAAGAAAGAAAGAAGAAAGTAAGGAAAAAGATTAAAACCAAGAGAAAACAAGAGAATTTAGACACAGCATTTGAGGCTTTTGAACCAAAGAGAAGTTTGAGGAGACCACTAGAGATAGATGAAACTAAGATTAGGATTATCAAATTGGACCCAGCTGAACAGCTCCGACAAAAAGAGGAAGAAACCAAAGCAAAACTAAAATTCCCGTACCAATGCCATCTGTGTTTCAAAGGCTTCAACTTTGAAGCCAAACTCAAGAACCACATGTTCAAACACAGTCCGTCCCGCGGCCCATACAAATGCTCGCTATGCTCTATGCATCTACCTACCGCATATTCCGCATCGGTTCACTCGTTGACGCACACGCTTCGCTACGAGTGCGTTCAGTGCGGACGACGCATGATTGACAGACTGGCCATCATTAACCATTACCGATCTCAACACGAAGGTGTTACATCGGTGTTTACTTGCCATCTCTGTGGGAAAATTTCAACCAACGACAAAACCCACCGCGGCCACATGCGGAACCACCACACCGGAGCCGGTCGCGTCACGTGCAACGAATGTGGGAAGAGCTTCGTCAATAAGGACTCCCTCATCGAGCATCAGCTAATACACCAAGGCGTCAAAAACTACGAATGTCCGGAATGTAAGAAGATGTTTCGGACGAGGAATCAAATCCGACACCACATGGTCAAGCATAGCGATTCCAAGGACTTCTATTGCGTTGAGTGTGATGTCAGATTTAAATCAGCTCACACATTGCGACAACATCTGAAGAGGACGACAAAGCACAAAGAGGGTAAAACCCCCAAGTTGGAGTGTCCAGTATGTTCGAAGGGGTTCTCATCCGCGAACGCACTGCAGGCGCACGTCCGCATCCAACACGAAGGTGTCAGGGAGCACCGCTGTCCGCAGTGCGACTCCGCCCTGGCCACCAGGGCTTCGTTGATGAAGCATATCAAAGCAGTGCATCGAGGCATTAGGGCTCCACCCGTTCATGTCTGCCATACGTGTGGGAAAATGTTTAGGGCCAAGAGCACGCTAACGAACCACGTGCGCACGCACACGGGCGAGAAGCCGTTCCCGTGCGCGGAGTGCGGCCGCAGCTTCGCGCAGCGCACCGCCATGCGCACGCACGTCAAGCTCGTGCACCTCAAGATACACCGCAGCGCCAAGATAAAACCGAAACTTCCTCCACCGCCGGAGCCTTTGCCCCAAAAAGCAGACATCTTCAAAGAAGACCCCCCCATCATGTTCGAGTGGGGTCGACAGAACCTCCCGTGCGAGTATTTCACAGTCACCGCGGGACCCTAA
Protein Sequence: MDKISENYESELKPDLECGKAICRCCLTTDKRLTRIDLFRSLFIDLADIVVTESDGLPQWICWECSALLLKSVKFKHKVLRAHAMLYDYHRRCAPFPIDGADPELTKYASPHLSTCTTLVFDTGKEKKIGYHQVLEHEKSIVKSQLDDILIVEADDTNFYDDQISVKDEAMLSDCDDNVPLHEIRSNKNECEGQLLPKTEIKEEKKERKKKVRKKIKTKRKQENLDTAFEAFEPKRSLRRPLEIDETKIRIIKLDPAEQLRQKEEETKAKLKFPYQCHLCFKGFNFEAKLKNHMFKHSPSRGPYKCSLCSMHLPTAYSASVHSLTHTLRYECVQCGRRMIDRLAIINHYRSQHEGVTSVFTCHLCGKISTNDKTHRGHMRNHHTGAGRVTCNECGKSFVNKDSLIEHQLIHQGVKNYECPECKKMFRTRNQIRHHMVKHSDSKDFYCVECDVRFKSAHTLRQHLKRTTKHKEGKTPKLECPVCSKGFSSANALQAHVRIQHEGVREHRCPQCDSALATRASLMKHIKAVHRGIRAPPVHVCHTCGKMFRAKSTLTNHVRTHTGEKPFPCAECGRSFAQRTAMRTHVKLVHLKIHRSAKIKPKLPPPPEPLPQKADIFKEDPPIMFEWGRQNLPCEYFTVTAGP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01151444;
90% Identity: iTF_00953789;
80% Identity: -