Basic Information

Gene Symbol
-
Assembly
GCA_002192655.2
Location
NDFZ01004754.1:93513-102287[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 26 0.036 3.4 8.9 0.1 1 23 43 65 43 65 0.95
2 26 0.6 57 5.0 0.1 2 23 89 111 88 111 0.95
3 26 1.3e-05 0.0012 19.7 3.3 1 23 135 157 135 157 0.98
4 26 0.00066 0.062 14.4 1.9 3 23 163 183 161 183 0.97
5 26 0.052 4.9 8.4 2.2 1 23 191 214 191 214 0.94
6 26 0.00015 0.014 16.4 1.0 1 23 220 243 220 243 0.97
7 26 0.15 14 6.9 2.7 1 23 249 272 249 272 0.96
8 26 1.3e-05 0.0012 19.8 0.8 1 23 278 300 278 300 0.98
9 26 1.4e-06 0.00013 22.8 1.0 1 23 306 328 306 328 0.99
10 26 0.0009 0.085 13.9 1.2 1 23 395 417 395 417 0.92
11 26 0.12 11 7.3 0.2 1 23 490 512 490 512 0.97
12 26 0.0017 0.16 13.0 0.2 1 23 516 538 516 538 0.95
13 26 0.027 2.6 9.3 0.3 1 23 543 566 543 566 0.95
14 26 0.0012 0.11 13.5 2.7 1 23 572 595 572 595 0.93
15 26 0.098 9.2 7.5 0.4 1 11 602 612 602 616 0.90
16 26 0.14 13 7.0 1.5 1 23 731 754 731 754 0.95
17 26 7.3 6.9e+02 1.6 0.1 2 23 779 801 778 801 0.78
18 26 0.23 21 6.4 0.1 1 23 825 847 825 847 0.93
19 26 0.00014 0.013 16.4 0.2 1 23 851 873 851 873 0.98
20 26 0.00015 0.014 16.4 0.5 1 23 878 901 878 901 0.96
21 26 0.011 1 10.5 0.4 2 23 908 930 908 930 0.93
22 26 0.1 9.6 7.5 6.5 1 23 937 960 937 960 0.96
23 26 8e-05 0.0076 17.2 4.7 2 23 967 988 966 988 0.96
24 26 0.0002 0.019 16.0 1.7 1 23 994 1016 994 1016 0.98
25 26 0.00029 0.027 15.5 0.7 1 23 1164 1187 1164 1187 0.95
26 26 0.29 28 6.0 2.0 2 23 1213 1234 1212 1234 0.96

Sequence Information

Coding Sequence
ATGATTCggctCGTCGAACTCACAGTAAAATGGAGACCGACACGCAAGTATAACGATCACAGAGATAATGCCGGTATCATTCTCGAAAGTTCCAACGCTTGCCCGTTTAGGTGGCGGCGAGGGTCCTTCGCGTGTGCGTACTGCCCGCTCTCTTTCGGAGACTTCAGCGGTGTCAAGCAGCATACCATAAACCACCCCAATCGGATCGAAGCTCTCCGCAAAGCCCGACCTTTTGCAAACGTCAAAATGGAAGTCACTGAGTTACGATGCGAAATATGTCTCACGCGTATGACGGACTTAGATGCTCTTTCCGAACATTTAatgaaaaatcataataaaccaATAGTCACGAAGCTCGGTTTAGGAGTCACGCCTTTCTATCTAACAGAAGACAAAGAAGAATACAAGTGCACTCATTGCGATGAAACTTTCGTTACTTTCACTAATTTGAACACGCATTTGAACTTGCACTACCCTAATAGTATCTGCTTTCAATGCGGGAAGGCGTTCTCGTCGATACATAGGTTAAAATCTCATTTGCTTACCCACGATGCTGCGACTACGTCTCAGCACAAATGCACTAGATGCGATCTAGTTTTCCCTACACGtgtcttaaaaaataatcacatcaCCCAAAAACACGGCCCGGAATTTAGATATAAGTGTCCTTACTGCAAAGAATCCTTCAAAAACTACGCCGACAGGGGGAGGCATTTGAAATCGGCGCATGACAAAAAGATCGAGTATCCTTGCCATTTATGTCCATCAGTTTTCGCCATGTGTAATCAAAGGACGAAACATATTAAACAAGTTCATATGAGAATTAAGACATTCTCCTGCACTTTTTGCCCGTACAAATTTGTGACAGCTGCTCAGTTGAGGAATCACATGATCAAGCATGGGGGAGAAAGGAAATATCAATGTCAGGTGTGCAAGAAAGCGTATGCCAGGAGTAAAACTTTGAGGGAGCACATGAGGATACACAATAATGATAAGAGATTTGTTTGTGAAGAACTGTCTGACGAAGATTGCCTTGTAGAAAATAAAGCAGAATTCAAGGCGCAGATCGCCATTGCAGAACGAAAGAAAACCTTTACAGACGACATTAAAGCTAGGACAAGACACGCAATTATACTGCTGGAATCAACGAATATATGCCCCTTCAAATGGATGAAAAATCTTTACATATGCTTCTATTGTCATCAGCAATTTTCTGACCCTGCATCGTTGAGGCAACATAACGCAGAACACGGATTTTTGACAGCTTCGCAAATCAAATACGCTTTGTCAAAGCTAAAGAAGTACGAACTAGTCAAAGTAGATATAACTGATGTAGGCTGCAAGCACTGCGATGATCTGATCCCAGATTTCCCGACACTAAAATGGCATCTGATAGAAAAGCATAAGAAAAATTTAGATCCGAAATTCGGGGATGGGGTCCTTCCGTTCAAAGTTACGCTGAACGATTTCCCTTGCGCtctctgtatggaaaaatacACGGAATTTAAGGCTCTAAACCAGCATATGAACGTACATTTCCAGAATTTTATATGCGAACAATGTGGTACGGGATTTATAACTCCAGAACGTTTGAGGACTCACGCGTTTTCGCACGAAACAGGGTCCTTTCCTTGCGACAGCTGTGAAAAAGTATTCCGGTCGACTAACGCTAAAAACGAACACTATGCTACAGTACACATGAAAGTGAAACGCCACAGATGCCCACACTGTCCCGAAGTATTTAGAAACTACTTTCAAAGAAATAAGCACATTTCTGCCGTCCACGGTTTGAAGTTAAAAGAATTCAAATGCACGATGTGTCCTAAAGTTTTCACTATCAGTGGATCGGACTCCGAAATACCAGACGTGAAGCGAAGAATCATCCCGTTATTCCAAGTATCTTACGACAGAAGTCTGTGTAGGCCTCTGGGGACTTTGATAGATTTCAATAGACTTCGACAGAAGAGTGTTAGAGCCATCTCTCCAGCTCAAACATTAGATTACTCTTCATCTCGTAGTCCATCACCAGTTTACGTAGAAAATGCACCATCTCCTTACATTGACAGTCCGCCGACATTGCCAATCCAAACTGTAAAGCCGAAAGTCAAGAAAACTCCAGATTTAAGGCAGAATGCTCTAGCTGTATTTGAATTTTCAACCGTCTACCCATTCATTTATGGGAGcaacaaattcaaatgttttgtttgctcACAGCCGTTTTTAGacttaaatgaattaaaactgCACATGCATTTGTCTCATACTTTTGCTCCTCTCAAGAGATTAGTGAATAATAGAAGAGAGAATGTTCTAAAAGTAGACGTAAGTAATATAACTTGCAAGATATGTTCAGATAAACCTCCTAGCCTTGTGGATCTCAAGCGTCACCTCAAAGAAATACACGATAAGCCCATGGATTTAGAACTGCAAGACAATATGATCCCGTTCAATCTCGAACTCGTAGACGATGCTTACAGATGCGTGATATGCGAACAGAGTTTTATAAAAGTGCGAATCTTAGTGATACACATGAGTGAACACTTTAATAATTACAGTTGCGAGATTTGCGGGTCGGTCTTCATGACTTTACGGCTCTTAAAGAAACATTTAGAGGTCCATGACTCTGGGAACTTCCCTTGCGATCGatgtaataaagtttttagtACTCCTTATAAACGGACTTTACACATACGAGGCGTGCATCTAAAGCAGTGTCCAAGAAGATGCCCGATGTGTCCAGAAAAGTTCAACTCGAATTATAAAAGGACGATACATTTACAAGATGTCCATAATCAGGAGACAAGGGTACATAAATGTAAGACTTGTGGCCGAGGGTTCAATCTGAAGTATCATTTGGTCTGTCACGTTCGTTCGGTTCATCTTCAAGAACGGAATCAGCAATGCGATGTATGTCACCAAAGGTTTTGTAACAAGGAATCTCTGAAGCGTCACATGGTTATACATACAGGGGAGAAGAATCATAAGTGTGACGTTTGTGGAATGGCGTTCCTGCGGAGGAAGAATTTGAAGGACCATTTGCGTTTGCATGATATTAgaaTCATCCAGAAATCCAACTCAACGATCACCCTAAAGGATGCAGATGGAAAAGAGATTAAACTCACGGTTCTCAAATATCCAATTCCTTTAAATACTCTAGAATATGAAGCTGATGATTATGTTCcaaacaataacattaaaaataaagacaaagagAAAACTCGCAAAAAGAAAGAGGCGAAGAGAAGCAACGTTAAATTAGGAAATATTTGTCTGTTGAAAGAACCAATTTCGATAAATAATCTCGATTGGAAGAGTGATGCTAATGAACAAGAAAATTCTATAACTTTCAATGTGAAAACTGTTCAAAGTTTTATCCGCGCACCAACAAGACAACGAAAAGAAAATGTTGACTACGAAAAATGGAAACAAAATGCTTTGATCATCTTTGAAAACTCCTATGTCTATCCATTTGTACACGCGGCTAACAAATACAAATGCGTCATGTGCTCCAAACCTTTTATAGATGCAAATCATTTAAAAGACCATACTATAAACGAACATACAAGCAAAGATATGGAAAGAGCGTTAGATAATAAAGTTAGAGAGAATAATCTAAAAGTCGATGTCACATATCTCCAATGCAAGATCTGTTTGCAAACACTACATGATCTCCAGACCTTGAAAACACATTTAAAGGACCATGGCCAGAAAATAAAGCCGGAATTGAAAGACAATATAATACCATTCAAATTAGGAGGCGAGGATTTTGAATGTCAATTGCGAAATTTGTGGATCCGTGTTCATATCATTGAATTTACTTAA
Protein Sequence
MIRLVELTVKWRPTRKYNDHRDNAGIILESSNACPFRWRRGSFACAYCPLSFGDFSGVKQHTINHPNRIEALRKARPFANVKMEVTELRCEICLTRMTDLDALSEHLMKNHNKPIVTKLGLGVTPFYLTEDKEEYKCTHCDETFVTFTNLNTHLNLHYPNSICFQCGKAFSSIHRLKSHLLTHDAATTSQHKCTRCDLVFPTRVLKNNHITQKHGPEFRYKCPYCKESFKNYADRGRHLKSAHDKKIEYPCHLCPSVFAMCNQRTKHIKQVHMRIKTFSCTFCPYKFVTAAQLRNHMIKHGGERKYQCQVCKKAYARSKTLREHMRIHNNDKRFVCEELSDEDCLVENKAEFKAQIAIAERKKTFTDDIKARTRHAIILLESTNICPFKWMKNLYICFYCHQQFSDPASLRQHNAEHGFLTASQIKYALSKLKKYELVKVDITDVGCKHCDDLIPDFPTLKWHLIEKHKKNLDPKFGDGVLPFKVTLNDFPCALCMEKYTEFKALNQHMNVHFQNFICEQCGTGFITPERLRTHAFSHETGSFPCDSCEKVFRSTNAKNEHYATVHMKVKRHRCPHCPEVFRNYFQRNKHISAVHGLKLKEFKCTMCPKVFTISGSDSEIPDVKRRIIPLFQVSYDRSLCRPLGTLIDFNRLRQKSVRAISPAQTLDYSSSRSPSPVYVENAPSPYIDSPPTLPIQTVKPKVKKTPDLRQNALAVFEFSTVYPFIYGSNKFKCFVCSQPFLDLNELKLHMHLSHTFAPLKRLVNNRRENVLKVDVSNITCKICSDKPPSLVDLKRHLKEIHDKPMDLELQDNMIPFNLELVDDAYRCVICEQSFIKVRILVIHMSEHFNNYSCEICGSVFMTLRLLKKHLEVHDSGNFPCDRCNKVFSTPYKRTLHIRGVHLKQCPRRCPMCPEKFNSNYKRTIHLQDVHNQETRVHKCKTCGRGFNLKYHLVCHVRSVHLQERNQQCDVCHQRFCNKESLKRHMVIHTGEKNHKCDVCGMAFLRRKNLKDHLRLHDIRIIQKSNSTITLKDADGKEIKLTVLKYPIPLNTLEYEADDYVPNNNIKNKDKEKTRKKKEAKRSNVKLGNICLLKEPISINNLDWKSDANEQENSITFNVKTVQSFIRAPTRQRKENVDYEKWKQNALIIFENSYVYPFVHAANKYKCVMCSKPFIDANHLKDHTINEHTSKDMERALDNKVRENNLKVDVTYLQCKICLQTLHDLQTLKTHLKDHGQKIKPELKDNIIPFKLGGEDFECQLRNLWIRVHIIEFT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-