Basic Information

Gene Symbol
-
Assembly
GCA_963924605.1
Location
OZ004600.1:80093196-80097132[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.25 18 6.5 0.5 1 10 466 475 466 489 0.78
2 12 0.00038 0.027 15.4 1.5 2 23 495 515 495 515 0.97
3 12 0.00058 0.041 14.8 0.2 1 23 521 543 521 543 0.96
4 12 5.6e-07 3.9e-05 24.3 0.7 1 23 549 571 549 571 0.98
5 12 5.4e-06 0.00038 21.2 2.6 1 23 577 600 577 600 0.97
6 12 0.00034 0.024 15.6 1.4 1 23 615 637 615 637 0.93
7 12 0.37 26 6.0 0.1 2 23 643 664 642 664 0.95
8 12 9.1e-05 0.0064 17.4 2.9 1 23 706 728 706 728 0.97
9 12 0.0011 0.076 14.0 0.7 1 23 734 756 734 756 0.96
10 12 3.7e-05 0.0026 18.6 1.7 1 23 762 784 762 784 0.98
11 12 3.2e-07 2.3e-05 25.1 0.2 1 23 790 812 790 812 0.99
12 12 0.00011 0.0078 17.1 2.0 1 23 818 840 818 841 0.95

Sequence Information

Coding Sequence
ATGTTTCCTAAAAACAAAAACGATAAAGAAATATGGTTTGCAAAAATAGTCTTAAATCCTGTGCTTTTAGAAGAAGCTAATAAAAACTATGTAAGATTTAGACGGCGTTACGGCGTGTGCGGCTTGCATTTTGAATTGAGTCAATATCAAACTAGTGAAAAAAAGAAACTTAATCGAAATGCAGTGCCAACAATCGTCTCTCTAGATGGGAAGTTAGATTACGGTAGGAAACCGACAGTTACTTTACCCAATAAAGAAACTGAAACAATACAACCAGAAAAACCACAACGTACTATAAAAGAACCTGTATATATGTATGatGATATAATAATGGGATATTATGAAGAACATATAAAACAAGTGGATGACACTGTAACGCTAGATGAATTACCAGAAAGGTCAGATGAGGAGATGAGAGGAGAGGAAAAATTAGAggaaaaattagaagaaaaaccAATGAAAGtaaaatatAAGACAAGGACTTGGCGTAAATGTGCAGTACCAAATTGTGTAAATGCCAAAACTAACTGGAACGCTGCTTATTTCACATTTCCAATGGATCAAAAATTACTTGAAGAATGGTTGAACGCAATTAAAAACCctaaattaacattattaaatacGGAAAAAACTGAAAAGATAAGAAGAAATCATGGAGTTTGTGCACGCCACTTTGAAGATTCTCAATTTAAATCAATTCGGAAGTTGTCGTTGAAATCAAAAGCCGAAATTCCTTGCAAGTTTTTATCAGAAGAGGAAGAACCAGACCCTATAAATGGATTACTTCTTCAAGTTGATCAAGGAAACGTGGGTACAGTGGTTTCTCAAATTCAAATGTCTGTTACAACTACCGTAACTGACATTGATAAAGAATCGTCGTGCCGAGTATGTTTAACAAAGACCGatcctaaaaatttatattgctTATTTGGAACGAATGCAATGTTTGAAGAACTATCTGTTGCAGCAGCTTTACAAGATTGTTTCAATATTTATttaAAAGAAGACGAAGAACTTCCAAACTACGTTTGTATTAATTGTGCATCCAGCACACTGCAAGCATATACATTTAGAAGATGTATTATAAAATGTCAATCAGTTTTAAAGTCGCAGAAAGTGGAAAAAGAAGATGACGAACTTAATCCAATAAATTTATCACCACAAGgaattttattcgattgtttaaCAAAGGACAAAACTGAAGATGTTGAACATACTATAAACAATGAAATTTCTGCTGAAGTATTTGAAGACAAAAAATGTGATCCTTTAATAGACCATAGTTACactaaagaaattataatagaaGATGAAAAACCTGCTGAGATTTTgccaacaaaaaaaaaagtaaaaagcgCCCCTGACAAGTGGTGGTTAAAAGAAAGAGGGCCTCCGTATCAGTGTAAAATTTGTGGTCGAAATTATGGTGTAAGATACTACGCATTTTATATGCACGTTCGTGCCCATCGAATGAACAAACCTTCATGTTCGCAATGTGGGAAAAAGTTTactagagataaaatgataGTTCACATGCGAAGTCATACAAAAGAGAAACCATTTGTTTGTGATCAATGTCCGGCTCGTTTTACAATAGAAGGAAATTTAAAACGTCACTTGTATTTGCATTCAGGTGAAAAGTTGTATGTTTGTGATGAGTGTGGTAAAGcTTTTACCCAATCGACAACTCTAATGAGTCACAAACAAACTCATTCGAAAGAAGTTCAATTTGTTTGTGAATATTGTGGCAAAATTTGCACAACTAACGGAAGTTTGCAAACACACATTCGTCAtattcataaatttattaaaagggaGGAAGCGGgcgattcaataaataaatatacttGTCAAGAATGTGATAAAGtttttaaatcgaAGGCTTCTTTAAGTTTTCATTCTAAAATTCACACATTCGTTAAACTAGAATGTAACCTATGTACTAAAATATTGTACTCGGATAATAATTATGATGTTCACATGCTGTGGCATCGTGTAATAGAAACTGACACAGCGAATGATGTTATTAAGAAGTGGGAATGTGAATTATGTAATGATATACATGAAGATCGAGAAGTATTAGCTTCTCATGTACTTTCGCATTCAGATCTACAGTTTGACTGTAATTATTGTTCTAAATCATTTCCTAACAGACAGGCTCTTGTGCATCATTCACGAAGACATTCagATGAACGACCATTTGCATGTCGTTCGTGTCCGAAGACGTTTAAATATGTTGCTACGTTACGACAACACGAAAAAGTTCATACTGGTGAAAGACCTTATCGATGTGACATTTGTGAAAGACAGTTTTCCCAGCAACAACAATTAATAAGTCATAAATatactcatacaggtgaaaaaaaaTATGTGTGTCCTTATTGTGGAAAAGCATTCGCTTTAAATGGCAATTTAACTGTTCATAAAAGACGACACACTGGTGAAACACCATACGTTTGTGACGTATGTCTCAAAGGATTTTATGATTCGAGTAGTTTGAAAAAGCATAAAACTATACATCATCGACGTTGA
Protein Sequence
MFPKNKNDKEIWFAKIVLNPVLLEEANKNYVRFRRRYGVCGLHFELSQYQTSEKKKLNRNAVPTIVSLDGKLDYGRKPTVTLPNKETETIQPEKPQRTIKEPVYMYDDIIMGYYEEHIKQVDDTVTLDELPERSDEEMRGEEKLEEKLEEKPMKVKYKTRTWRKCAVPNCVNAKTNWNAAYFTFPMDQKLLEEWLNAIKNPKLTLLNTEKTEKIRRNHGVCARHFEDSQFKSIRKLSLKSKAEIPCKFLSEEEEPDPINGLLLQVDQGNVGTVVSQIQMSVTTTVTDIDKESSCRVCLTKTDPKNLYCLFGTNAMFEELSVAAALQDCFNIYLKEDEELPNYVCINCASSTLQAYTFRRCIIKCQSVLKSQKVEKEDDELNPINLSPQGILFDCLTKDKTEDVEHTINNEISAEVFEDKKCDPLIDHSYTKEIIIEDEKPAEILPTKKKVKSAPDKWWLKERGPPYQCKICGRNYGVRYYAFYMHVRAHRMNKPSCSQCGKKFTRDKMIVHMRSHTKEKPFVCDQCPARFTIEGNLKRHLYLHSGEKLYVCDECGKAFTQSTTLMSHKQTHSKEVQFVCEYCGKICTTNGSLQTHIRHIHKFIKREEAGDSINKYTCQECDKVFKSKASLSFHSKIHTFVKLECNLCTKILYSDNNYDVHMLWHRVIETDTANDVIKKWECELCNDIHEDREVLASHVLSHSDLQFDCNYCSKSFPNRQALVHHSRRHSDERPFACRSCPKTFKYVATLRQHEKVHTGERPYRCDICERQFSQQQQLISHKYTHTGEKKYVCPYCGKAFALNGNLTVHKRRHTGETPYVCDVCLKGFYDSSSLKKHKTIHHRR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00950922;
90% Identity
iTF_00950922;
80% Identity
iTF_00950922;