Mfla012865.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Malthinus flaveolus
Gene Symbol
ham
Assembly
GCA_950108345.1
Location
OX467288.1:547437-569003[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 0.027 1.8 9.3 0.1 2 23 324 346 323 346 0.94
2 9 0.00088 0.06 14.0 2.9 1 23 353 376 353 376 0.94
3 9 4.5e-08 3.1e-06 27.5 4.2 1 23 382 404 382 405 0.96
4 9 1.6e-06 0.00011 22.6 1.7 1 23 411 433 411 433 0.95
5 9 4e-05 0.0027 18.2 5.0 1 23 439 461 439 461 0.99
6 9 0.086 5.8 7.8 0.6 2 21 469 488 468 489 0.94
7 9 1.4e-08 9.3e-07 29.2 0.7 1 23 807 829 807 829 0.98
8 9 1.8e-06 0.00012 22.5 1.6 1 23 835 858 835 858 0.97
9 9 1.4e-05 0.00095 19.7 3.4 1 23 864 886 864 886 0.99

Sequence Information

Coding Sequence
ATGATAACTGCCGTCACGTTAGGATTTCCGACTCGTAATCCTAAGCAAACAGGCACTATATTTATGTACGTACAATCGACGTTACAAGCTGTAAAAGTTATCTTCCAAGGAAGCGAAGATGAATTAGAAGTATCGACAGAAGATCACCAATTATCTGGCGACGAAAATTCTATGGAACCGACGATGGTACCGCcacaaaacgaaataaatttatcaagttCTCCTCTAGCCCAATCGTTAAGATCTGATccgataaataataataaagaagacCAACCGAGATCGTAcaataaaaacgaattaaattcaaaattatgcCTAAAGTCTGCCGAATTGTTATACAATAATCACGAAAGATTACTAAATTTAGATAAAGCGAATAAGTTCTTTAacgaaaattataataacgaATATTTAAACGATTGCGGAAAAATCTTTAATAAGAAAGAAATCGATTGCGTTAGAGAATTTGCAACGAGGATAAATTCGAATGTCGTGCTTGGGAATAATGTGATTCCTCCAGAATTGGAGTTTCGCGATTCTGGAATATATGCAGTTAGTTTAATTAACAAGGGGACGCGTTATGGTCCCTTTCAAGGTAAATGGGCCGGTATACCGCAGGATTCAAAATTTGCCTGGGAGgtTTTAGCAGGTTCGGGAATACGTGGATGGTTAGATGGATCGTCCGAACCTCACAATTggttaaaactaataaattgttCGTCGAATAAGAATGTGTCTAATTTAAGGCACTTTTTGCAAAGCGGGCAGTTGTGGTACGAAACATGCATAGACATTCAAATCGGACAAGAGTTAATTTTGGGTTCGAAAGAACCTCTAAATTTGCAGGATATGTTTGGTGATTCTAATGCTTCTGCTGACGATATTGCGAGTCGAGAGAcagGCTCTCAACATAGTGGTACCGTAGAGAACGAACGAGAAGATGAAAGTGAAGACGAATCCGAAACGAGATGTTTAGTTTGCGAACAACCATTTTCAGATTTAGACAAattGGACGAGCACCTCATAATCAAACACAACTATCGAAAAGACGAATTTCGCTGCGAACTTTGTCCAAAATCCTACTCTCATAGGCCTTGTTTACTGAGACACAGAGCTCTAGTTCACGACGAAATCCGAAAGTACCATTGCGAAAACTGCACTAAAgtTTTCACCGATCCGAGCAATCTCCAAAGGCACATAAGGACCCATCACGTCGGTGCGCGTTCTCACGCTTGTCCAGAATGTGGTAAAACGTTTGCGACGTCATCTGGTCTCAAACAACATACCCATATTCATTCTTCCGTAAAACCCTTCCAGTGCgaagtttgttttaaagcTTATACGCAATTTTCCAACTTGTGTCGTCATAAACGGATGCACGCCGATTGTCGCATGCAAATTAAGTGCGTTAGATGTGCTCAATCGTTTTCGACGGTCACGTCACTCTCTAAACATAAGCGATTCTGTGATACCACCAATCCGACGGCGCCTTCTTTAAACTCGACACCGCCGCAATTTCCTCTGAGTGCCATGGCGAACAACAATCCATTTAATATGTACCGTTCGACGACGACTTGCCACATACCAATTTTCCCCAGTCATTTTCCACCGTACCCGCCATTTTTTCACCCGAACGCTCCGCCACCGTCATTTATGAATCCGCTAATATACAACCCgctctcaaaattaaaagccTTAGAAAATCCAGAACACAATCCGCCTAAACGCTTACGAACGTCGAGTCCAGAAAGAGAGTCGCCTATAAAAGAACGCACGACACCGCCGCCGCCACAAACGCCAACAATAACAGAAAAAATAAGCCCACCGACGGCGGAAGAAGCGTGCTCGATGTTGATGCCGTCGCCGGCGCGACCGTCGCCAAGTTCCAACGTAATTTACACCAACCCACGTAATCAAATAGAAAGAGAGCAGTCTAAAGATCGCCCAAAAGACCTGACCAAAAACCCGGCGACGAAACGCGAAGAAGGCGACCAACCGTTAGATTTGAGCGTCGGAAGAAAGCCcaacgaaacaaatttttacgaTACTCCACGTTCGAACGACGTCACGCCGACCaaacaagaagaagaaaaaatcgaaGTGGTCGACGTAGAAGAACTCGCACCGAAACAAATCGAAAGTCCCAAGAATACTTTACCTCAAATGGCTTATCCACGACCGATTCACCCTCTACTGTTGGAAATGTACAGGCCAAATTTTCAAGCACTACAAGTACCACAAAACAACGATCGTTTATTACCACATCCTTTTGGCCCGAGACcattttcgtttataaatcCGTTGCAACATGGAAGAAATTTCGATTTAATGAGACCGGACGTGCGTTGTTTCGGATCCGTTAAGCCTTACCACGACGTCATACAGCAACAAACGCAAGGAAAAATGAAGGATAGGTATGCATGTAAGTTCTGTGGGAAGGTTTTCCCGAGATCCGCTAATTTAACTCGACATTTACGCACTCACACCGGAGAACAGCCCTACAAATGTCGCTACTGCGAACGTTCGTTCAGCATCTCGAGTAATTTACAACGACACGTGCGTAACATACACAACAAAGAGAAGCCGTTCAAATGTCCGTTGTGCGAAAGATGCTTTGGGCAGCAAACGAATTTAGATAGACATTTAAAGAAACACGAAGCGGATGACGGTAACGGTGGTACCGCTATAGCGGATTCGCCCGGTAGCAGTAACGAAAACGAACGCGAAGACGCTTATTTTGACGAAATTAGAACGTTTATGGGTAAAGTTACTTATTCCGGCggtaataatagttttaataatcaaaCCCAATTGTACACCCCGAGACGTAATAATAGCGGAATCGATGTGATAGGAAAAGAAGAGGACGATTCGGAAACTTATTCGGAAGAGGCGTCGCTCGAAGAttataccaaaaataaattcgattcCAACTCCTATAATAATCGTAACGTTAAACAAGAAAAGgacgaaattattaataacaacgACCAAGGCTTAGAAATTTCGACTTAg
Protein Sequence
MITAVTLGFPTRNPKQTGTIFMYVQSTLQAVKVIFQGSEDELEVSTEDHQLSGDENSMEPTMVPPQNEINLSSSPLAQSLRSDPINNNKEDQPRSYNKNELNSKLCLKSAELLYNNHERLLNLDKANKFFNENYNNEYLNDCGKIFNKKEIDCVREFATRINSNVVLGNNVIPPELEFRDSGIYAVSLINKGTRYGPFQGKWAGIPQDSKFAWEVLAGSGIRGWLDGSSEPHNWLKLINCSSNKNVSNLRHFLQSGQLWYETCIDIQIGQELILGSKEPLNLQDMFGDSNASADDIASRETGSQHSGTVENEREDESEDESETRCLVCEQPFSDLDKLDEHLIIKHNYRKDEFRCELCPKSYSHRPCLLRHRALVHDEIRKYHCENCTKVFTDPSNLQRHIRTHHVGARSHACPECGKTFATSSGLKQHTHIHSSVKPFQCEVCFKAYTQFSNLCRHKRMHADCRMQIKCVRCAQSFSTVTSLSKHKRFCDTTNPTAPSLNSTPPQFPLSAMANNNPFNMYRSTTTCHIPIFPSHFPPYPPFFHPNAPPPSFMNPLIYNPLSKLKALENPEHNPPKRLRTSSPERESPIKERTTPPPPQTPTITEKISPPTAEEACSMLMPSPARPSPSSNVIYTNPRNQIEREQSKDRPKDLTKNPATKREEGDQPLDLSVGRKPNETNFYDTPRSNDVTPTKQEEEKIEVVDVEELAPKQIESPKNTLPQMAYPRPIHPLLLEMYRPNFQALQVPQNNDRLLPHPFGPRPFSFINPLQHGRNFDLMRPDVRCFGSVKPYHDVIQQQTQGKMKDRYACKFCGKVFPRSANLTRHLRTHTGEQPYKCRYCERSFSISSNLQRHVRNIHNKEKPFKCPLCERCFGQQTNLDRHLKKHEADDGNGGTAIADSPGSSNENEREDAYFDEIRTFMGKVTYSGGNNSFNNQTQLYTPRRNNSGIDVIGKEEDDSETYSEEASLEDYTKNKFDSNSYNNRNVKQEKDEIINNNDQGLEIST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00951195;
90% Identity
iTF_00951195;
80% Identity
-