Mfla011370.1
Basic Information
- Insect
- Malthinus flaveolus
- Gene Symbol
- -
- Assembly
- GCA_950108345.1
- Location
- OX467287.1:12239197-12247820[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 21 1.4e-05 0.00096 19.7 0.4 2 23 222 244 222 244 0.96 2 21 0.93 64 4.5 4.3 1 21 678 698 678 699 0.94 3 21 0.59 40 5.1 5.3 1 23 728 751 728 751 0.92 4 21 0.15 10 7.0 0.4 5 21 764 780 762 781 0.92 5 21 0.0001 0.0069 17.0 0.9 2 23 883 905 882 905 0.95 6 21 0.15 10 7.0 0.3 3 23 914 935 914 935 0.95 7 21 0.38 26 5.7 0.0 1 23 954 976 954 976 0.95 8 21 0.00014 0.0097 16.5 0.5 2 23 980 1001 979 1001 0.97 9 21 0.00012 0.0084 16.7 0.7 2 23 1025 1046 1024 1046 0.93 10 21 0.55 37 5.2 1.4 1 23 1070 1093 1070 1093 0.93 11 21 0.057 3.9 8.3 1.8 2 23 1105 1126 1104 1126 0.97 12 21 7.4e-06 0.0005 20.6 6.2 1 23 1158 1180 1158 1180 0.98 13 21 0.69 47 4.9 0.8 3 23 1202 1222 1200 1222 0.96 14 21 0.00012 0.0082 16.7 3.5 1 23 1245 1267 1245 1268 0.95 15 21 0.0037 0.25 12.1 0.1 2 23 1280 1302 1279 1302 0.96 16 21 7.3e-05 0.005 17.4 0.1 1 23 1319 1341 1319 1341 0.95 17 21 0.0043 0.29 11.9 0.5 1 23 1369 1392 1369 1392 0.95 18 21 0.029 2 9.3 1.7 2 23 1403 1424 1402 1424 0.97 19 21 9.6e-05 0.0065 17.1 2.1 1 23 1436 1458 1436 1459 0.95 20 21 6.4e-06 0.00044 20.7 0.4 1 23 1467 1489 1467 1489 0.98 21 21 0.0082 0.56 11.0 0.0 1 23 1509 1532 1509 1532 0.95
Sequence Information
- Coding Sequence
- ATGGGTGAACGCAGATTgggtaattttaattcgtgtTGTCGTTTGTGCTTGTCGGAGAAATTGGGCACGTTAAAGTCCATCTTCGAAGATGATTCGAAAGGTCAGGAGATGGCTAGGAATATTAAGCATTTTCTTGGAGTTCAGATTTCTCATAACGACAAGTTGACTACGATGATTTGCGAAAATTGTTTCGGTCAAATACACGAttggaaactttttaagaaaaattgtgacgaaaaccaaacaaaattagtgGGGTGGATGAATTCGTGGAACGACAGTAATATTGGAAATATATCGATACGTATAAAAGATGAAATTGTGGAAGATGTAGACGATAGGCCGATCATAGTAGAAGACGACGATGTTGTTCATGTAAAAACCGAGCAACAAGAACAGGAGAGTAGGGACGAGGTGCAAGCAAATTCGTACGGAGGCGAACCGATGGATGAAGACATGTACGACTTGCCACCACCATTAACACCTCATATGCCCGGTGAGTCGGCATTACACGGAGATGATGAGAATGGACAAGCGGTCGATGTTTTTTCagacgacgaggacgacgacgaaaACATGAGTATGCTCGTCCCTTGTATAGAATTTTCGGAAGGAAGAGAAGTGTTaaTGAATGGTAATTCTAACGACGATGTTAACCAACGCGAGTGCACTATTTGTGGTAAAGAGTTCAGTACGCCGGCAAACCGTAAGAAGCACGAACGGATGATCCAtttaagaaaaacgaaaaaacagGATTATGattTACGGGAAATCGCAGAAAGAGCGGAAGAAAGTTTATTGGCcgaaaaaagcaaacaaaggTACGAGAAGGCCTACAATTGTTTCAAGTTTTGGTGTAACGAAAAAGGAGTTCAGGATGTAGGATCAGAAACGGTTATCCTAGATTATTTTAGTGAAATGTCAGAAAGTAAAAAAGCGCCATCGTTATGGTCTATATATTCGATGTTGCGCACAACACTTGCCCGTAAAGAAAGAGTCGACATATCCAAATTTGGAAAACTATTgacgtttttgaaaagtaaaaacgtTGGATACAAAGCAAAAAAGTCCACCACTTTTACAATGAATAacattgaaatatttttaaaggatGGACCCGTGAGTTTTCTTGTCCATAAGgttgCGCTAATAATTGGAGTGTCGGGGGCCTGTAGATCTGATGAACTCTACAAAATGAAACTGGAAGacgttaattttttagaaaaaaaagtttgtattgaAATACCTAACACAAAAATCCACCTGTCAAGAGCGTTTATGGTCACCAACGAAGGAtggattaaaataattagagaGTATATGGATCTccgaaaaaatattcaaaatgaaaaattctttATGCAAGTTAGATTAGGAAAAATGACGAATCAGTCTATTGGCCACAATACCATCAGCCaatttcccaaaaaaattgcagcTTTTTTAAATCTCCCTAAAATTGACACCTACACTGGACACTGCTACAGACGAACGGCGGCTACTTTACTTATTAATAATGGAGGAGACATTACGCAACTAAAGAGGTTGGGAGGACGCAAATCATTGTCAGTTGTAGAGGATTATATCGACAGCTCTGTGAGCAATCAAGTTCAAACGGCTAGGATGATATCTAAAAATTCTAACATAACAGTTGCTGAACCAAGCTCTAATAGCCCATCTTTCGGCTCGACAACAACACAAGCTTTccaaatttcttcaaaatcaGTTGCACAGGgtgCATCAAATATACAAGACTCAGATTATAATCGAGGGCAAACACCACCGACCGAACTAATCGAATTAGAAAAGATACAATTTGCAGCTGGCTTGCGTTTACAACAACGTTCTTTAAATCAACAAGTAACTATCGAAAGTGCGACTCTTAGCGAAGTCGAAGTTGCTTATTTAGATAAATGCAAGACGATAGTTCATATGAAAGAAACCTTAACTTGTGCCTGTCACGGCGAATcttttaacgaatttaaagATCTTTTTGTGCATTTAAAGAAACAGCGTACTTGGTTTTCAGTATTTACTTGTTATAATTGTTTGATAACGTTTGGCGATAGGTCGTCTTATATGAAACACTACTGTCATTGCCCTAAGACCGAGTTGCAGTATCTCAAACGTCTAACCGAAGGGCCCGTAAACcccgaaataaaaattcgtatctatcaaaattttaagtgcacTAAGTGCGACTGTACGTTTGGTTTTCACGAAGATTTTGCTAGTCACTTCGATGTCCAACACACGGAGTTGTTTGAAAGTGACCCTCCTTTTACATGTATATGTTCCAAGTCGTTTTCTGATATCGATGATTACAAACAACATCTGCACATTGCATGCTTTCTACGTCATTTTTGTGATGTTTGCTTCGACGAATTTTCTAGTGTGGACGAATTTCGACTGCACTGTTACAAAGTACACGATAAAGCCGACGGTGGTACGGTGGAATCATATGATACTTACAACAAGTGTAAACTCGATTCGAACGACGAAGATTTGCCTTCCACGTCGAGGTATTCTCTGCCCAATTTTTCGGTTAAAGCAGATCCTGACGGCGATAGACGACAAACACTCGATTCGCGTCACCTTATTTCAGCGTCGGCTGTTAGAAATATAACAAAGTCGTCTGAACCTTTAAATTGCCCACTGTGCGGGAAGCCTTATTCGTCATATCACAATATGTTGAGACATTACAAAATGGCGCACGATAAAAGTGGTAAAATACTCGGCTGTGATTATTGCCCGGAAAGATTTAGACTGATATCTGAAATGAGAGAGCACGAGTTAAGTTTTCACGCCGAGGAATGCGCAAGTGCCGAGGACTCGTCTAAACAAAAAGACCAATTTAACTTCTCGTGCCCAGATTGTGGCGACTTATTTCAAACGGTCGAAGAATGGAAGGAACACGCCGAAACTCATCCCACAAAAACGTGCGAAGAGTGCGGTAAAGAATTCAAATTACAAAGTGAACTCGACCAACATCGTAGCGTACACTTAAACATTAAAGTGTATCGTGACTCAGAAACTCAGGATTATAAGAGCGCCATGAGCTCTCCTTCTATGGTTTGCACAATTTGCAATAAAACGTTTGAGTCGAAAATAGaattaaagaaacataatttgttgcaTAGAAAAATGCCTGTTTTAAGCGCCCACGATGATGCCGAAGACGATAAAAAGGAAGTCGTTACTAAAAAGTATAGTTGCTTAGAGTGTAATAAGCATTACATTAGTTACGGCGGTATTTGGGACCATAATAAGAAATATCACGGCGGGAAGTCCGTCGAAAACGATTATCCTAAAAAATGCCACCAGTGCGATAAGTTGTTGAGCTCTAAAGGTGCTTGGGTAAATCATAAAAGGTGGCACGATCGCCAAAGTCCTTCACAATCGAACGTACCACCCGTGGCTGTAACCACACGTCGAACTAGTAGACACGGCGACGAGGAAGAGGAATCGTATCACACGTGTAAACGATGCTTCAAGGTATTCTCCAGTCGATACAATTTGAGGAATCACATGAGAAGTCACGGCATTAATTTAGCTCCAAATAGAAGTAGTACTAAAACtggtaaagttaataaaaccTTTTGGTGCGATGTTTGTCATCAAGCTTGTCCTGGTTATGCCGAATTACAAGAACACAAACAAGAACATATAGctaaaaaatcaaaagctTCTCAACAAGCACTATTGAATGATCTACAAAGGAAAGAAACCGAGTTCCCTTGTACATACTGCAATCTCACTTATACGAAAAACTTCAACCTCTTAAGACATATAGAAAAACACCATGGGGAACAAATGGACTCGAAGCCTCCtgcaatttattgcaaatattGCAAAGTTCCATTCGAAGAGGTCGGCGATCTAAATGACCACATGCAAACCGAACACGAAGAACTATACAACAAGCCGAAAGAAGAAAAAGCAGCTGTTAGAAAGTTTCCGtgtaaaatttgcaaaaaagtgTTTGACAATTCAGCCGCACTCGCCTCTCATCAAGGTTGGCACAAAAGAGGCAAATTTggcaagaaaattttaaatcagaaGTATCACATGAACAACCCGTCGACTGTATCGGAACAACCCAACTTCACGTGCCGTAGTTGCTCGAGAAAGTTTGTCAACGAAACCGCCttacaaatacatattttagaAACTCATAGAAATATTAACACGACAATATTATCCATGAAATGTAACAGTTGCAAATTAACGTTTGATTCCAAAGTTAAATATGACAACCACATGCAATTACACGAAGTCGTCGAAAGTCAGAGACATTCCAAGGCGCATCCGTGTAATTATTGTTCCGCCGGATTTAGTAGGAGCGATACATTGAACGCGCACGTGAGACAACACCACAAGGAATTTTATAACGATATTTTCAGATGTAACGAGTGCGATCGGGTGTTTGACAAACAAAATGCACTCACGATACATCTTAAAGTACACGAGAAACAACGCACATCTggtgaagttacaataaaaaatgcgAACAATAAAAGTATGtatttttgttcgatttgTGATTTAGGTTTTGTAATCGCTAAGGATTTACGTAATCACGTTGTTACCGCTCATCCGTTCTAA
- Protein Sequence
- MGERRLGNFNSCCRLCLSEKLGTLKSIFEDDSKGQEMARNIKHFLGVQISHNDKLTTMICENCFGQIHDWKLFKKNCDENQTKLVGWMNSWNDSNIGNISIRIKDEIVEDVDDRPIIVEDDDVVHVKTEQQEQESRDEVQANSYGGEPMDEDMYDLPPPLTPHMPGESALHGDDENGQAVDVFSDDEDDDENMSMLVPCIEFSEGREVLMNGNSNDDVNQRECTICGKEFSTPANRKKHERMIHLRKTKKQDYDLREIAERAEESLLAEKSKQRYEKAYNCFKFWCNEKGVQDVGSETVILDYFSEMSESKKAPSLWSIYSMLRTTLARKERVDISKFGKLLTFLKSKNVGYKAKKSTTFTMNNIEIFLKDGPVSFLVHKVALIIGVSGACRSDELYKMKLEDVNFLEKKVCIEIPNTKIHLSRAFMVTNEGWIKIIREYMDLRKNIQNEKFFMQVRLGKMTNQSIGHNTISQFPKKIAAFLNLPKIDTYTGHCYRRTAATLLINNGGDITQLKRLGGRKSLSVVEDYIDSSVSNQVQTARMISKNSNITVAEPSSNSPSFGSTTTQAFQISSKSVAQGASNIQDSDYNRGQTPPTELIELEKIQFAAGLRLQQRSLNQQVTIESATLSEVEVAYLDKCKTIVHMKETLTCACHGESFNEFKDLFVHLKKQRTWFSVFTCYNCLITFGDRSSYMKHYCHCPKTELQYLKRLTEGPVNPEIKIRIYQNFKCTKCDCTFGFHEDFASHFDVQHTELFESDPPFTCICSKSFSDIDDYKQHLHIACFLRHFCDVCFDEFSSVDEFRLHCYKVHDKADGGTVESYDTYNKCKLDSNDEDLPSTSRYSLPNFSVKADPDGDRRQTLDSRHLISASAVRNITKSSEPLNCPLCGKPYSSYHNMLRHYKMAHDKSGKILGCDYCPERFRLISEMREHELSFHAEECASAEDSSKQKDQFNFSCPDCGDLFQTVEEWKEHAETHPTKTCEECGKEFKLQSELDQHRSVHLNIKVYRDSETQDYKSAMSSPSMVCTICNKTFESKIELKKHNLLHRKMPVLSAHDDAEDDKKEVVTKKYSCLECNKHYISYGGIWDHNKKYHGGKSVENDYPKKCHQCDKLLSSKGAWVNHKRWHDRQSPSQSNVPPVAVTTRRTSRHGDEEEESYHTCKRCFKVFSSRYNLRNHMRSHGINLAPNRSSTKTGKVNKTFWCDVCHQACPGYAELQEHKQEHIAKKSKASQQALLNDLQRKETEFPCTYCNLTYTKNFNLLRHIEKHHGEQMDSKPPAIYCKYCKVPFEEVGDLNDHMQTEHEELYNKPKEEKAAVRKFPCKICKKVFDNSAALASHQGWHKRGKFGKKILNQKYHMNNPSTVSEQPNFTCRSCSRKFVNETALQIHILETHRNINTTILSMKCNSCKLTFDSKVKYDNHMQLHEVVESQRHSKAHPCNYCSAGFSRSDTLNAHVRQHHKEFYNDIFRCNECDRVFDKQNALTIHLKVHEKQRTSGEVTIKNANNKSMYFCSICDLGFVIAKDLRNHVVTAHPF
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -