Basic Information

Insect: Malthinus flaveolus
Gene Symbol: ZFX
Assembly: GCA_950108345.1
Location: OX467286.1:22909784-22911652[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 1.2e-05 0.00082 19.9 0.9 2 23 127 148 126 148 0.97

2 15 0.0064 0.44 11.3 0.6 1 23 165 188 165 188 0.93

3 15 1.3e-05 0.00085 19.8 0.6 2 23 216 237 216 237 0.97

4 15 0.12 7.9 7.4 5.3 1 23 243 265 243 265 0.82

5 15 3e-05 0.0021 18.6 1.5 1 23 273 295 273 295 0.98

6 15 2.5e-05 0.0017 18.9 0.4 1 23 301 323 301 323 0.92

7 15 5.7e-05 0.0039 17.8 1.4 1 23 329 351 329 351 0.98

8 15 3.5e-07 2.4e-05 24.7 0.3 1 23 357 379 357 379 0.98

9 15 4.1e-06 0.00028 21.4 0.8 1 23 385 407 385 407 0.98

10 15 1e-05 0.00069 20.1 2.0 1 23 412 434 412 434 0.96

11 15 5e-07 3.4e-05 24.2 0.3 2 23 440 461 439 461 0.97

12 15 0.00048 0.033 14.9 2.0 1 23 467 489 467 489 0.97

13 15 7.1e-05 0.0048 17.5 1.0 1 23 495 517 495 517 0.97

14 15 1.5e-07 1e-05 25.9 2.4 1 23 523 545 523 545 0.99

15 15 0.00012 0.008 16.8 2.1 1 23 551 575 551 575 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	1.2e-05	0.00082	19.9	0.9	2	23	127	148	126	148	0.97
2	15	0.0064	0.44	11.3	0.6	1	23	165	188	165	188	0.93
3	15	1.3e-05	0.00085	19.8	0.6	2	23	216	237	216	237	0.97
4	15	0.12	7.9	7.4	5.3	1	23	243	265	243	265	0.82
5	15	3e-05	0.0021	18.6	1.5	1	23	273	295	273	295	0.98
6	15	2.5e-05	0.0017	18.9	0.4	1	23	301	323	301	323	0.92
7	15	5.7e-05	0.0039	17.8	1.4	1	23	329	351	329	351	0.98
8	15	3.5e-07	2.4e-05	24.7	0.3	1	23	357	379	357	379	0.98
9	15	4.1e-06	0.00028	21.4	0.8	1	23	385	407	385	407	0.98
10	15	1e-05	0.00069	20.1	2.0	1	23	412	434	412	434	0.96
11	15	5e-07	3.4e-05	24.2	0.3	2	23	440	461	439	461	0.97
12	15	0.00048	0.033	14.9	2.0	1	23	467	489	467	489	0.97
13	15	7.1e-05	0.0048	17.5	1.0	1	23	495	517	495	517	0.97
14	15	1.5e-07	1e-05	25.9	2.4	1	23	523	545	523	545	0.99
15	15	0.00012	0.008	16.8	2.1	1	23	551	575	551	575	0.91

Sequence Information

Coding Sequence: ATGAATAAGTTCAACAATTTATCGACGAATTTAGTCTTGACTAAGGTGTGTCGTGTCTGTATGAATTCACTCGAAAACAacaatatttctttatttacatCGAGTACTATTAGCGCAGTTACGCTCGCAACTAAAATGGTCTCTTTCACAGGCTTACAAGTAGATTTTGAGGATTGCTTACCGAACTTCGTGTGTTTGTCATGTTCGAACCAAATTGAAAATGCGtatctattaaaattgcaatgcGAAGAATCGGATTTCACTTTAAGAGGCTTCTTGAAGCCCGTCATAAATAATCTAGTCTCCGATTTTGATGACGCAACTTCAGATTCTGATTTGTTCACCAACCCTAATCAACAAGAACCAGCTAAAAAAATTCGGTGTTCGAACTGTGGAGCTTCTTTTGATACACAAAATCAATTGAAAACACATAGGAAAATTCATGCCAGAAGCAAAACTAAAGAAGCAAACAGTCCCGATTCAGAAAATATTCACATTTGTACTGCTTGCGacggaaaatttaaaacaaacgatGAATTCATCGAGCACATGTTGGCAAAGCACGTGGAAGCGGAAGCTTGCGAACCGGATGCTTGCAAACCGGAAGCTTGTGAACCGGAAGTTGTAAAAGAGCAAGAGAAGAACGTGTGTAATATTTGCAATAAGATGTATTTAACGGCTTCTAATTTAGACAAACACATGAGAACTCACACAGGAGAAAAACCCTTTGAATGTGATATATGCGGTAAAAAGTTCACTCAAGGGCGAGCCCATGCTTGTCACATGCGAACTCATTCTGATGCTAGCATAAAACCCTACACTTGTGAAGTgtgtaaaaaagaatttattggAGAACATCAATTAACCGATCACATGAAAAACCATTATAGTGGAAAATCATTTGCTTGTATTATTTGTGGAAAAATTTGCAGCAATGCTGGAAATTTGAACTCGCATATGCGCTTACATACTGGAGATAAGCCGTATGCATGTAACATTTGTGGAAAGACTTTTGCCCAAAGTAACGCACATACCTATCACATGCAAACTCATTCTGgAGAGAAACCTTATGTTTGTGATAAATGTCCAAAAGCTTTTACTACAAACGGCCAACTTATAAATCATACTCGCTTACATACTGGCGAGAAACCCTTCTCATGTAACCTTTGCCCTAAAAGCTTCGCACAACAAACTTCTTACACGCTACACATGATATCACATACGGGAAAACCACATGCGTGTAGTATTTGTGggaaaaagtatttcaaaaGTAATCAGTTGGAGGAACATATGCGTATGCACAATGGACAACCTTTACAGTGCAATATTTGCGGAAGGACGTACACCACTACCGGAAATTTAGGAGCTCACATGAAAACTCACACCGGCATTAAAACTCACATATGTCAGGTTTGTAATATGGGCTTCTATGCatctaataaattatcaaaacacATGAGGACGCATACTGGCGAAAAACCCTATTCTTGTACTTTTTGCCCAAAACGTTTTAGCAACTCCGcagttttgaaaattcacaatAGGCTACATACGGGAGAACGTCCTTATAAATGTGAAACTTGTGGTAAAGGGTATACCAACAGTTCGCATCTGAAGGTTCACACTCGTGTTCATACAGGAGAGAAACCGTATATGTGTACAATTTGCTCACGAGGCTATACTACATTGTCAAGCTTAAAAGCACATTTAAATTCTTGTCGCCACGCTGGAGATACAATAACTTATATAAATttcatataa
Protein Sequence: MNKFNNLSTNLVLTKVCRVCMNSLENNNISLFTSSTISAVTLATKMVSFTGLQVDFEDCLPNFVCLSCSNQIENAYLLKLQCEESDFTLRGFLKPVINNLVSDFDDATSDSDLFTNPNQQEPAKKIRCSNCGASFDTQNQLKTHRKIHARSKTKEANSPDSENIHICTACDGKFKTNDEFIEHMLAKHVEAEACEPDACKPEACEPEVVKEQEKNVCNICNKMYLTASNLDKHMRTHTGEKPFECDICGKKFTQGRAHACHMRTHSDASIKPYTCEVCKKEFIGEHQLTDHMKNHYSGKSFACIICGKICSNAGNLNSHMRLHTGDKPYACNICGKTFAQSNAHTYHMQTHSGEKPYVCDKCPKAFTTNGQLINHTRLHTGEKPFSCNLCPKSFAQQTSYTLHMISHTGKPHACSICGKKYFKSNQLEEHMRMHNGQPLQCNICGRTYTTTGNLGAHMKTHTGIKTHICQVCNMGFYASNKLSKHMRTHTGEKPYSCTFCPKRFSNSAVLKIHNRLHTGERPYKCETCGKGYTNSSHLKVHTRVHTGEKPYMCTICSRGYTTLSSLKAHLNSCRHAGDTITYINFI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -