Basic Information

Insect: Malaya genurostris
Gene Symbol: THAP3
Assembly: GCA_030247185.2
Location: CM058072.1:345995004-345997431[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 2.5 1.9e+02 4.0 0.3 2 13 131 142 130 144 0.88

2 8 0.16 13 7.7 1.4 1 21 458 478 458 479 0.94

3 8 8.3e-05 0.0065 18.1 6.3 1 23 530 552 530 552 0.97

4 8 0.017 1.4 10.7 1.4 1 20 560 579 560 581 0.94

5 8 0.00011 0.0083 17.7 1.1 1 23 616 638 616 638 0.97

6 8 1.9e-05 0.0015 20.1 0.4 1 23 644 666 644 666 0.98

7 8 9.4e-05 0.0074 17.9 0.4 1 23 672 695 672 695 0.94

8 8 0.93 73 5.3 0.1 1 17 701 717 701 718 0.85

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	2.5	1.9e+02	4.0	0.3	2	13	131	142	130	144	0.88
2	8	0.16	13	7.7	1.4	1	21	458	478	458	479	0.94
3	8	8.3e-05	0.0065	18.1	6.3	1	23	530	552	530	552	0.97
4	8	0.017	1.4	10.7	1.4	1	20	560	579	560	581	0.94
5	8	0.00011	0.0083	17.7	1.1	1	23	616	638	616	638	0.97
6	8	1.9e-05	0.0015	20.1	0.4	1	23	644	666	644	666	0.98
7	8	9.4e-05	0.0074	17.9	0.4	1	23	672	695	672	695	0.94
8	8	0.93	73	5.3	0.1	1	17	701	717	701	718	0.85

Sequence Information

Coding Sequence: ATGCCATCATCATGCACAGTGCCAGATTGTGAGCTTAAATACAACCATTCAGATGATGTGTCGTACCACAAATATCCGCTAAAGAAACCCGACTTGCTATTGCAATGGATTGCGTTTGCGGGACGAGGTCCTGATTGGATTCCGAACAAGTGGAGTGCGATTTGCAGCCGTCATTTCAAACCTAGCGACTTCAAGGATTGCATCTACAGaaaaaatcttatAAGCACAGCAATTCCTTCGGTTCGAATAAAGCATCAAACACCAATTGCGGAACTGATAGCGGGTAAAGAAGAATCTGAATTCCATCATGAGTCGCATTCTGAAACTCATGAAATGGAAACCGATCCGGAGGATTTATCCGGAGGAGAGGAGTCGCAACTTCTCGACATGACTTGCCGACTGTGTGGCATTGTATTCAGCAAGTGGTGCCTGGGATTGTTGTCGGATTTTCAGCAACACGTAACCCTGATCATGAAATGTTTGCCATTCATCAATCTGGATCTGGTACAATTTCCGACCAAAGTTTGCGCCAAATGTTTAAaagtgttgaatggattttcaacCTTCCACGATAACGTAGTGAAAGCTCAAAATGATCTGGAACGAAAGTACAATGGTCTCTACGAGCATTATTCGGCGAATGTTCCCACAGTGGAACCTTCCAAAGCCATGAAAATTAAGCAGGAGCCCCTGATGAGCATTAAAGAGGAAACCGTCGATACGGCAGTGAAGATTAGAGATAATATGCAAGAGATAGCGGAAAACACTCTGATCATCAAGAATCCAAACATTACCAACGATATAAATAAGGTACTACTGTTCAACAAACAACCGGGCGAGGGTCAGTATTCCAAGCAAACTCGTGAATCGAAAAACtgcgaaattctagaaattgtaAATCTTTACCCTCCGATAGTGGACATTACGAGTGCGACCATTCGAGAGGTTCAACCTTATGAAATTACTTTGCCCTCGTCGCTGTCCAGTTTTAACCCGATAGcgccacagattttcaatttgaaaacggAAAACACTACCGAAGCAGAAGAAAACTACGAGGACTATACCGGATATTTCCAAGATTTTTTGGCTGGTTTCAGTGCCTGGGAAGAGCATAGCTACTCGAAGCTTCCAGTTCAGGCGGACGACAACAAAGACGAAGTTTTTCCGTCACATCAAGAGCTTGAACCGTCCGACTCCATCAACTTGGGCAATTCGGGAACCGTTCGAGTAATTCACGTCGAGCTTCCACCGGCGCCTCCAAcaagtttgaaatatttatgtCCGCTGTGTGCGCAGCACAAGTTTCAGTCGCGAAGAAAGTTGCTAAAACATCGAATTCTGCTGTGTTCTGGTAGAAAAACAAACCCTTATCGATGCCTGTACTGTCTGCAAAAGTTTCCATCGTCGTTCAATAGACAGTCTCATCTGACGACGTGTCGTCGTAGGACATTTCAACGATTACTCAGATGTAGAAGAGCGAAAAAAGTTTTGCAGAGTAGACAAATGAAGAAATTCGAAAGCCGCACTCCTACGCCAGATGATGCTGGTTCAAATGGTGTGCCACGGCCCCGACGGGTGGCTCGTCATCATTGTAAACTATGTGATAGGTCCTATTCCCGAATGTACAATCTTAACCGACACATGAGTAGTCATCGGCCGGTGGATCAGTGGAATCATAAATGTGGAGTTTGTCAGAGGATTTTCGACAAACTGTTCGATCTGaaaaaacattttcagttgtcgaAATGCATGGGCGGTACGGATGTAGATAATAACGAGACAAATTCCGTCAGTTTGGATGAATGCGGTGCGGCCGAGAAACCCCCTAGCGATCGATTGTTGTACGTCTGTTCCACATGTGACAAACAATTCAAGTCGTacaacagtttaaaagttcatgagAGCATTCATACGGGTTTAAAAATATTCGTCTGTGAAACTTGCGGGAAACGATTCGGTGGTCAAGTCAATCTGTCACAGCACAGGATGACTCACGTCGACGTTAGGCAGTTTGCGTGTAAACTGTGTCCAAAGGTTTTCAAACGAACCGGCGGTCTTAATCAGCACGTTAAGGCATTCCATATGAAAATCAAACCGTACCAGTGTACCGTTTGTCGAAGAGATTTTGCCCTCAAAGCAGACATGACTCGGTGTCGGCACTCGAAGCTAAAAGAGTTTACCTAG
Protein Sequence: MPSSCTVPDCELKYNHSDDVSYHKYPLKKPDLLLQWIAFAGRGPDWIPNKWSAICSRHFKPSDFKDCIYRKNLISTAIPSVRIKHQTPIAELIAGKEESEFHHESHSETHEMETDPEDLSGGEESQLLDMTCRLCGIVFSKWCLGLLSDFQQHVTLIMKCLPFINLDLVQFPTKVCAKCLKVLNGFSTFHDNVVKAQNDLERKYNGLYEHYSANVPTVEPSKAMKIKQEPLMSIKEETVDTAVKIRDNMQEIAENTLIIKNPNITNDINKVLLFNKQPGEGQYSKQTRESKNCEILEIVNLYPPIVDITSATIREVQPYEITLPSSLSSFNPIAPQIFNLKTENTTEAEENYEDYTGYFQDFLAGFSAWEEHSYSKLPVQADDNKDEVFPSHQELEPSDSINLGNSGTVRVIHVELPPAPPTSLKYLCPLCAQHKFQSRRKLLKHRILLCSGRKTNPYRCLYCLQKFPSSFNRQSHLTTCRRRTFQRLLRCRRAKKVLQSRQMKKFESRTPTPDDAGSNGVPRPRRVARHHCKLCDRSYSRMYNLNRHMSSHRPVDQWNHKCGVCQRIFDKLFDLKKHFQLSKCMGGTDVDNNETNSVSLDECGAAEKPPSDRLLYVCSTCDKQFKSYNSLKVHESIHTGLKIFVCETCGKRFGGQVNLSQHRMTHVDVRQFACKLCPKVFKRTGGLNQHVKAFHMKIKPYQCTVCRRDFALKADMTRCRHSKLKEFT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00948825;
90% Identity: iTF_00948825;
80% Identity: iTF_00948825;