Basic Information

Insect: Malaya genurostris
Gene Symbol: topi
Assembly: GCA_030247185.2
Location: CM058072.1:340669158-340670964[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.043 3.3 9.5 0.0 2 20 210 228 210 230 0.93

2 11 0.03 2.3 10.0 0.9 1 23 236 259 236 259 0.94

3 11 1.6 1.2e+02 4.6 7.0 1 23 298 322 298 322 0.90

4 11 0.0024 0.19 13.5 0.3 1 20 339 358 339 360 0.95

5 11 0.47 37 6.2 3.0 1 23 370 393 370 393 0.94

6 11 0.047 3.7 9.4 8.2 1 20 399 418 399 421 0.95

7 11 5.7e-06 0.00044 21.7 3.6 1 23 427 450 427 450 0.98

8 11 0.00016 0.013 17.1 1.7 1 23 456 478 456 478 0.99

9 11 1.4 1.1e+02 4.8 5.8 1 23 484 506 484 506 0.97

10 11 1e-05 0.00079 20.9 1.2 1 23 512 534 512 534 0.99

11 11 6e-05 0.0047 18.5 6.9 1 23 540 562 540 562 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.043	3.3	9.5	0.0	2	20	210	228	210	230	0.93
2	11	0.03	2.3	10.0	0.9	1	23	236	259	236	259	0.94
3	11	1.6	1.2e+02	4.6	7.0	1	23	298	322	298	322	0.90
4	11	0.0024	0.19	13.5	0.3	1	20	339	358	339	360	0.95
5	11	0.47	37	6.2	3.0	1	23	370	393	370	393	0.94
6	11	0.047	3.7	9.4	8.2	1	20	399	418	399	421	0.95
7	11	5.7e-06	0.00044	21.7	3.6	1	23	427	450	427	450	0.98
8	11	0.00016	0.013	17.1	1.7	1	23	456	478	456	478	0.99
9	11	1.4	1.1e+02	4.8	5.8	1	23	484	506	484	506	0.97
10	11	1e-05	0.00079	20.9	1.2	1	23	512	534	512	534	0.99
11	11	6e-05	0.0047	18.5	6.9	1	23	540	562	540	562	0.97

Sequence Information

Coding Sequence: ATGGAAGAACAATGCAGAACCTGCATGGTGGATATTGGTCATCAAGATGGATCAAAATCAGTATTTAGTGATACACCAGAAGGACATAcaattgcttctttgcttctgaaATATTGCTGCCTGAGTATTTCAGAACACGACCAACTTCCGAAACATGTCTGTGATCGTTGTGTGGAAGAACTACTGGCGTTTACGAATTTCCACCGTCAATGTGaactttctgaacaaacttTTCGGGACATCGGTGGAACCATGAACAATGACGTAGCCGTGGGTGATATTGACGTCCTAGATCAAAAATCTGCAGCCGATGAACAAGAAATCGAAGACGACATCCAGATCACGGGAAACAGCCAACAATCCGTCAATACGGACACACAAATTGATTTTCCAATTGTCGAAGCACTAGAGGAAAACTTGACCacagaaaataatcaaaacctAGATCAACTGATTGATCATAATGGAGATGATATACAATTGTGCTATAATGTAGTCGAAATGATGAGTTTCCGATGTTGCGTATGTTCGAGCATCTTCTACAGTCAAGAGGATCATCAGGAGCATGTTGAGTTGGTGCATGAAATTACGTTCCCACGAGATGCTTCAGATGCTAGGACACAGCCTGAATGCTTCATATGCCAACAAGTGTATGCTACTTTAGAGGATCTAGAATTGCACCAGGGGACCAGCTTTATGGAACTGTTTCAATGCAATCATTGCGATAACATTTATGAAACCGTCGACAATGTCATACAGCATTACGAGCAAACGCATCAGCTTGGGCCGACAAATAATAGTGAACACAGTTCTTGTTCCGTCGAAGAACGAACCGTCGAGAAACCAATGCCGAGAAAAAACAGCTCAAATACTAGCACATCATCGGGACGCTACTGCTGTGTAACACATTGCCACGCAAATTTTTCGAATGAGAAACACTTAGTTGAACATGCCCAGCAGAAACATGCGGTGAAACTGAAGTATAACCAAGAGAAAAACACTCCAAATAAACCATTTGTTTGCAGCGTTTGCTTTCGCTCGTTTGGCTCTATAAAGAATCTCAAAGTCCACCAGTTTGTTCGTGCCAACGTCGTTCGTGGAAAGCATTTTTTGTGTAGCCATTGTTCATTCCGTACAGGTAGTCGTAATCTGCTAACCATCCATGAACGATCGAAACACAGTGGAGAACGACCATTTGAATGTTGTTATTGTGACAAACGATTTTTCAGTGAGCTACATCTGAAAAATCATATGATATGCCATTCATCGGAGCGTCCCTTTGAATGTTCAATCTGCCAGAAAAGTTTTAACAGGAAACGAAATATGGAAGAACACATTCGTTCATGTCACTCCGAGGATAAACCGTTCAAATGTGAGTTATGTACGGCTCGATTTAAAGTACCCCAGCATCTACGTATTCATACCAGGATCCACTCCGGGGAGAAACCGTATAAATGTTCCTATTGCGATAACAGCTATTACCACATAACCGATTGCAAAAGGCATGAAATGGTGCACACCGGTGAAAAACCGTACAAATGTGACAATTGTGAGGCGGCTTTTACCAGGAAGCGAACGTTGAAAATTCACGAAAGAACTCATTCAGGGGAGCGACCTTACTGCTGCGTAATTTGTGGGAAAGGGTTCTGCCAGAATGCCACACTCAAAAAACATATGCATCGTCACGAACGTATCGGCGATGACGCTACTGAAGCGGTAGAAATGCTCGCCGATTACGATTAA
Protein Sequence: MEEQCRTCMVDIGHQDGSKSVFSDTPEGHTIASLLLKYCCLSISEHDQLPKHVCDRCVEELLAFTNFHRQCELSEQTFRDIGGTMNNDVAVGDIDVLDQKSAADEQEIEDDIQITGNSQQSVNTDTQIDFPIVEALEENLTTENNQNLDQLIDHNGDDIQLCYNVVEMMSFRCCVCSSIFYSQEDHQEHVELVHEITFPRDASDARTQPECFICQQVYATLEDLELHQGTSFMELFQCNHCDNIYETVDNVIQHYEQTHQLGPTNNSEHSSCSVEERTVEKPMPRKNSSNTSTSSGRYCCVTHCHANFSNEKHLVEHAQQKHAVKLKYNQEKNTPNKPFVCSVCFRSFGSIKNLKVHQFVRANVVRGKHFLCSHCSFRTGSRNLLTIHERSKHSGERPFECCYCDKRFFSELHLKNHMICHSSERPFECSICQKSFNRKRNMEEHIRSCHSEDKPFKCELCTARFKVPQHLRIHTRIHSGEKPYKCSYCDNSYYHITDCKRHEMVHTGEKPYKCDNCEAAFTRKRTLKIHERTHSGERPYCCVICGKGFCQNATLKKHMHRHERIGDDATEAVEMLADYD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -