Mgen006577.1
Basic Information
- Insect
- Malaya genurostris
- Gene Symbol
- -
- Assembly
- GCA_030247185.2
- Location
- CM058071.2:136654629-136659352[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 5.7e-08 4.5e-06 28.0 2.8 1 23 72 94 72 94 0.98 2 13 0.0058 0.45 12.3 0.1 1 23 100 122 100 122 0.96 3 13 4.2e-07 3.3e-05 25.3 0.3 1 23 127 149 127 149 0.98 4 13 5.2e-07 4.1e-05 25.0 2.2 1 23 155 177 155 177 0.98 5 13 5.1e-06 0.0004 21.9 4.9 1 23 183 205 183 205 0.99 6 13 0.00011 0.0087 17.7 1.9 1 23 211 233 211 233 0.96 7 13 1e-05 0.00081 20.9 3.4 1 23 239 261 239 261 0.99 8 13 0.00015 0.011 17.3 5.0 1 23 267 289 267 289 0.98 9 13 0.25 20 7.1 2.6 1 19 295 313 295 317 0.95 10 13 7.7e-07 6.1e-05 24.4 1.7 1 23 325 347 325 347 0.98 11 13 2.2e-05 0.0017 19.9 2.4 1 23 349 372 349 372 0.96 12 13 1.8e-06 0.00014 23.3 1.3 1 23 377 399 377 399 0.99 13 13 3.6e-05 0.0028 19.2 4.9 1 23 405 428 405 428 0.95
Sequence Information
- Coding Sequence
- ATGTTGATAGGCTACAAAGCAGGCTCGGATATGGACGAAAATATTGATTTCGAAGTGAAAACCGAGAAACCTAACGAGGAAGCAGCAAATAGGAATGATGTGTGTAGTTCCGAAGAAACTTTTCCAGACACAGAAGAGATGGCTTCGAACTGTAGTGAATATATTGCAGACGAAATGGATTCCGAAGACACGCAAAACGGCGGCGGGCATCGCTTCAGCTGTCCCTACTGCGATAAACATTTCATTCAGCAGTTTAATTTGGAGCGTCACATGCTGACGCATACCGAGGGAACGCCGTACCGATGTGACATTTGCGGTAAAGGCTATCTGGAACTGGGTGCGTTCAAGCGGCATCAGTTGGGACACTCCAAGCAACCGTACAGATGTGATGTATGTGGAAGAACTTTTGCCATTCAGTCTTTGCTCAAGACGCATATGCGGGGTCATACCGGCGAGCGACCGTTCGTTTGCACTGTATGTGGAAAAGGGTTTAAAAACAAACACAACATGAAAGATCACTTGAGAATACATACCGGAGGGCATAGGTATCAGTGCGATTTTTGCGGCAAAGGATGTAGTACTAAGCGTCATTTGCTAATTCACATGAGATCCCATACCGGAGAGCGTCCATATGAGTGTGAGATATGTGGGAAACACTTCGTAACTGTCTGTTCACTGAGAAATCACGGTAGTGTACATAAGACGGATCTTTTGTTCCAGTGCAACCGTTGTGATAAACAATTCGCTTTCGACCGTCAACTCAAGCGTCACATGAAAACACATAACGAAGAGCGCCCCCATCAATGCGGTTTTTGTAACAAAACGTTCAAGCTCAATTACCAGTTCGTCCAGCACATGCGTAATCATACGGGGGAGAAGCCATATAAATGCAACTTGTGCAGTTCATCCTTCATTTCCGTTGGTTATCTTAATGTTCACTTTACATGTCACCTGGAGCGAGATAAAAGACCATTTGAATGCGAAATATGTGGGAAGAGGTTTACTCAAAAAACTAAGCTTAACATTCATAGTAAAACACATTTATACCAATGTTGTGATTGCAATGTACGGTTTGCGACCAAGAGCGACCTCACAAAGCATAAGATTTCCGTTCACAAGAAAAAGTCCTACGAATGTACAACCTGTCAGAGAACTTTCTTCACAAATGGAAACCTACGAGCTCATCTGCTAACTCACACTAAAGAGTGTCCATTCAAATGCACAAAATGTGAACGAAGCTTCACTCGGGAATGCAATCTTAACCGACATCTAGCATATAGACACGAGCAAAACATATCGACTGTGGAGATTTCTTCCGGGAAAGAAATCGATGACGTTCCGCTATAA
- Protein Sequence
- MLIGYKAGSDMDENIDFEVKTEKPNEEAANRNDVCSSEETFPDTEEMASNCSEYIADEMDSEDTQNGGGHRFSCPYCDKHFIQQFNLERHMLTHTEGTPYRCDICGKGYLELGAFKRHQLGHSKQPYRCDVCGRTFAIQSLLKTHMRGHTGERPFVCTVCGKGFKNKHNMKDHLRIHTGGHRYQCDFCGKGCSTKRHLLIHMRSHTGERPYECEICGKHFVTVCSLRNHGSVHKTDLLFQCNRCDKQFAFDRQLKRHMKTHNEERPHQCGFCNKTFKLNYQFVQHMRNHTGEKPYKCNLCSSSFISVGYLNVHFTCHLERDKRPFECEICGKRFTQKTKLNIHSKTHLYQCCDCNVRFATKSDLTKHKISVHKKKSYECTTCQRTFFTNGNLRAHLLTHTKECPFKCTKCERSFTRECNLNRHLAYRHEQNISTVEISSGKEIDDVPL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -