Mneu003680.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Malacosoma neustria
Gene Symbol
L
Assembly
GCA_963693495.1
Location
OY856373.1:13107562-13117418[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.55 52 5.4 5.8 1 23 3 25 3 25 0.97
2 16 7.4e-06 0.0007 20.7 4.1 1 23 31 53 31 53 0.99
3 16 2.3e-05 0.0022 19.1 0.1 1 23 59 81 59 81 0.98
4 16 0.00058 0.055 14.7 0.0 2 23 97 119 96 119 0.95
5 16 5.2 5e+02 2.3 0.1 9 23 150 165 146 165 0.93
6 16 0.33 32 6.0 0.1 3 23 219 239 218 239 0.97
7 16 0.65 62 5.1 0.0 3 23 254 274 253 274 0.91
8 16 1.6e-05 0.0016 19.6 1.1 1 23 282 305 282 305 0.94
9 16 0.028 2.7 9.4 0.1 1 23 310 333 310 333 0.92
10 16 7.4e-05 0.0071 17.5 3.4 1 23 384 408 384 409 0.96
11 16 0.00017 0.016 16.4 0.1 2 23 479 500 478 500 0.96
12 16 0.051 4.8 8.6 0.0 1 23 508 530 508 530 0.98
13 16 1.1 1.1e+02 4.4 0.7 2 23 538 559 537 560 0.93
14 16 0.76 73 4.9 0.3 1 23 634 656 634 656 0.94
15 16 0.0032 0.31 12.4 0.2 1 20 664 683 664 686 0.95
16 16 0.045 4.3 8.8 0.6 1 23 693 715 693 715 0.94

Sequence Information

Coding Sequence
ATGCCATTTCGGTGCGAGTTCTGTTCGCGGTTGTTCAAACACAAGCGCTCACGGGATCGTCACGTCAAACTGCACACCGGCGACAGAAAATACCGCTGTGCACATTGCGAATCCGCTTTTTCCAGAAGCGATCATCTAAAGATCCACATGAAAACACACGACAATCAGAAGCCGTTTCAGTGTACTGTCTGCAATCGCGGCTACAATACGGCGGCCGCCCTCACCTCTCACATGCAAGGGCACAAGAGAGATCGCGAAGGGCGTGAGCCAGATCGACGCCGCGCGTTGCGCTGTTTGCGCTGTGGGGATGCTTTTCGCCGTCCAGACTTACTTCAGGCACACATGGCGAGTGCGCATGGGGTGGACGCCACGGCGATGACTCCGCCACGAAGAGTAGCTTCTCAAACTCCCACAACTTTTCTAGCTTGCATTTATTGCACCCGTGACACGTTCACTAGCATGGAACAATTGCAGCTGCATGTACGAGCAGCCCACAGCGCTCTACTGAATGGCGAAGCGTCAATACAAGCATGTGTCGACCAACCTGCACCCACAGATCTCAGCAGGAGAGTACCCGATGATGGACCGGCAATCAAAAGGCCCAGATCGGAATCTGGAATACCACAAACTACACTGTCTCCAGGCACACTTCTCTGCAACCAGTGCGACGCAGCACTCCCTGACTTTGAGGCATTTCGAACTCATTTAAAAGGCCATCTTGAAGAAGGAGGTGAACTAGGACGTGGAAGTCCCGCCCCCTGTGTACACTGTGGGGCCACATACGCCGATGCGGCTGCTTCGGAACGACACCTCACAGCGCACTACCTCGCGGTCTCCTGCGAATACACTTGTCACAGCTGTGCCCGCAGCTTCTCAACGCCCGACGATTTACAAAAACATCTGCTGGATCTACATGCTCATCACTTGTACCGGTGCTCGTTGTGCAAGGAAATTTTTGACTCAAAAGTCGCGATACAGGTGCACTTTGCGGTGGCTCATAGCGGCGAGAACAAGGTGTGGGTGTGTCGgtcgtgcggcagcggggcgggcGCGCTGCGTTCGGAAGGCGAGGGTGCGGCGCATGTGCGCGCACGCCACGCGGCCTCGGTGGCGCGGTGCGCGTGCGGCGCGCTGCTGCCTGCACCCCGCTACCGTTGCCCAGTGCCCGACTGCTCGCACACCTTCGCCGTCCAGTACTTACTTGAGAGACATATGCACACACACCATGCCGCTGTGCCATCTGCTCATCGGTCTTTAAATGGAGAGTTGGCGAGAACAAAACGTCCTGAAAACAAAAACGGTAGCGAGAACACTGATAGTCCATGTTCACCAAACGAACGCAATGTACGAAGTGATAGTGTTGGTATACCTAGTGGGCCGATTACGGGTACCCCTGGAGAGGAAAGGCGGAGGAAGAACGGAGCAGTAGCTCTACAGTGCGCGTATTGTGGGGAGCGCACGCGCAGCCGCGCTGAGCTGGAGGCCCACACACGCGCTCACTCGGGGGCAGCCGCTGCCAGGCACAAGTGTCTTATATGCGACGAGGTCCTCCCATCCGCTGCGGTACTTGCGGAACACAAGCTTACACATTGTAAGGTAGTAGCTGGTGACACGTGCGCTCGTTGTCGCGCTAGGTTACCATCTGAAGAATCCTTCCTTAACCACATGGCACGACATCATCCAGCTCTTCCAGCCCCATGTGTTGTTTGTCGTCAAACCCTGGGTACGGAAGCAGAGGCAAGACTCCACGCTCGCTTTCACCTCCGACCAACTGAAGACGAACAGAGATGCGCTCTATGTCTCCGTACTCTGCCTGAGGGAGAAGCAGGCGAAGGTGCTCGAGCGTGTTCAACCTGCTACGCTCGACATGCTGCACCAAGACCTTCTCTGCCAGCAGATCACGACTGCCGGCTCTGTCGCCGTGCCCTCGGCTCCCCCACGCGCCTCCAGGCACATCTTATAGAACATACATTTGCAGGAATAGGCGCATTTACTTGCTATTTGTGTTCGGCAGTTTTCACCAGTGCTACAGGTCTGCAGCGACACTTGCCAGAGCATGCAGCGGCTCCGAGGCCTTATGACTGTACCCGGTGCGGTCTGAAATTTTTCTTCCGCGCAGAATTAGACAATCACGCATTTGTGCATTTGGAGGAAGCAGAAATTGCACAACGCGCTTTTTACGAAGCGTATTCTCGAGGCGCTGCCTCGGCATGGGCGGCCCTTGTGCCTGAACCACCTCAGTCGGTAGCTCTACCAGCGGCGCCTGCGGTGGAAGTTAAGAAAGAACCGGAGATAAAGGAAGAACGCAACGATGAATACATTGAAGTCGCTTCACCTGCGCCGCCTCCTGTATCCGAGCCGTCGCCGACTGAAACGGAATCCTTACCTCCTCCAGTGATTAAACAAGAAAAGCCCGAGGAAGCCTGA
Protein Sequence
MPFRCEFCSRLFKHKRSRDRHVKLHTGDRKYRCAHCESAFSRSDHLKIHMKTHDNQKPFQCTVCNRGYNTAAALTSHMQGHKRDREGREPDRRRALRCLRCGDAFRRPDLLQAHMASAHGVDATAMTPPRRVASQTPTTFLACIYCTRDTFTSMEQLQLHVRAAHSALLNGEASIQACVDQPAPTDLSRRVPDDGPAIKRPRSESGIPQTTLSPGTLLCNQCDAALPDFEAFRTHLKGHLEEGGELGRGSPAPCVHCGATYADAAASERHLTAHYLAVSCEYTCHSCARSFSTPDDLQKHLLDLHAHHLYRCSLCKEIFDSKVAIQVHFAVAHSGENKVWVCRSCGSGAGALRSEGEGAAHVRARHAASVARCACGALLPAPRYRCPVPDCSHTFAVQYLLERHMHTHHAAVPSAHRSLNGELARTKRPENKNGSENTDSPCSPNERNVRSDSVGIPSGPITGTPGEERRRKNGAVALQCAYCGERTRSRAELEAHTRAHSGAAAARHKCLICDEVLPSAAVLAEHKLTHCKVVAGDTCARCRARLPSEESFLNHMARHHPALPAPCVVCRQTLGTEAEARLHARFHLRPTEDEQRCALCLRTLPEGEAGEGARACSTCYARHAAPRPSLPADHDCRLCRRALGSPTRLQAHLIEHTFAGIGAFTCYLCSAVFTSATGLQRHLPEHAAAPRPYDCTRCGLKFFFRAELDNHAFVHLEEAEIAQRAFYEAYSRGAASAWAALVPEPPQSVALPAAPAVEVKKEPEIKEERNDEYIEVASPAPPPVSEPSPTETESLPPPVIKQEKPEEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01437318;
90% Identity
iTF_00432487; iTF_00433362;
80% Identity
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