Mneu013699.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Malacosoma neustria
Gene Symbol
-
Assembly
GCA_963693495.1
Location
OY856382.1:6847750-6878568[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 20 0.00013 0.012 16.8 3.4 1 23 415 437 415 437 0.97
2 20 0.0037 0.35 12.2 0.7 1 20 443 462 443 465 0.94
3 20 6.4e-05 0.0061 17.7 5.5 1 23 484 506 484 506 0.98
4 20 8.2e-06 0.00078 20.5 4.9 1 23 512 534 512 534 0.99
5 20 0.00014 0.013 16.7 5.7 1 23 540 562 540 562 0.97
6 20 7.3e-06 0.0007 20.7 7.4 1 23 568 590 568 590 0.97
7 20 7.3e-07 7e-05 23.8 2.9 1 23 596 618 596 618 0.97
8 20 0.0001 0.0095 17.1 6.7 1 23 624 646 624 646 0.97
9 20 3.5e-06 0.00034 21.7 6.4 1 23 652 674 652 674 0.98
10 20 4.8e-07 4.6e-05 24.4 1.9 1 23 680 702 680 702 0.98
11 20 9.5e-06 0.0009 20.3 7.7 1 23 708 730 708 730 0.98
12 20 8.5e-06 0.00081 20.5 6.8 1 23 736 758 736 758 0.98
13 20 7e-07 6.7e-05 23.9 4.9 1 23 764 786 764 786 0.97
14 20 7.2e-05 0.0069 17.6 3.4 3 23 794 814 792 814 0.92
15 20 2.7e-05 0.0025 18.9 6.0 1 23 820 842 820 842 0.97
16 20 1.8e-07 1.7e-05 25.8 5.8 1 23 848 870 848 870 0.98
17 20 1.6e-05 0.0016 19.6 8.0 1 23 876 898 876 898 0.97
18 20 3.5e-06 0.00033 21.7 6.9 1 23 904 926 904 926 0.98
19 20 0.00053 0.051 14.8 0.3 1 23 933 955 933 955 0.96
20 20 0.24 23 6.5 4.6 1 23 965 987 965 987 0.99

Sequence Information

Coding Sequence
ATGAATCAAGAGCATCACAATTTAAATACGGCAGGCCAGCCCCCGGGAAGTGCCGAGTCTCAGAATCAGAGAGTTCAAGCGGTACAACAACAGCAATCTAACCTACCTCCTACGACATCTCCGACGGATTTGAGAGTGAACTCTGCAGCTGTAAACGTTGCTTTGTCTAGCGTTGCCAAGTATTGGGTGTTTACAAATCTGTTCCCGGGCCCAATACCACAAGTGTCAGTGTATGGTTTACCAGCGGGCACCAGAATTGAAAACGGGAAGCCTGTGCAGGATATAAGCCAAGGACATGCCAGTATTCTAAATGGGGATCCAAACATAATTCTTGGGCACCATGGAGGTCAACAACAAGTCACAGTTACGGGTCCAGGGAACCAGCAGATTCCAGTCACCCAGATCATCACCACCCAATCTGGGCAGACACAtgAAGCGTTGGTGGGTCACAGCACGCAGCAGGAGCTGGGGGGCACAGGAGCGTCACAAGGTCCAAATGCCAACACGCACCAGGTACCCACCAATCGGGTCGAATTTGTACACCATAACATTGATATGAGTCATCATTCACAACACATAATGCAGCAGCAGTTGATGGCAACAACAAGACCAGATCATTCAAATCAGCAGATTCAACTGACAGTCAGCGAAGATGGCACAGTGACAGTGGTGGAGCCGGGTGCTACCAAAATGGTAGAAAAGGAAGAAATGCATGAAGCAATCAAAATGCCGACGGACCACACCCTCACTGTTCACCAGTTGCAGCAAATTGTTGGTCAACAGGTGATAGACAGCGTGGTGCGCATCGAGCAGGCGACAGGCGAACCGGCGAACATCCTTGTCACTCACAACCCGGACGGGACGACATCGATCGAAGCGAGCGCCGTAGATCCTCTCATCATCAAAGATGAGAAGGCCGCGCCCAAAATGGACGCCACTGCGCAGTTCGCTATACCCACCGATATCAAGGATATAAAAGGCATCGATCTTAAGAACGTGGGAGCGATGGGTATGGAGGGCGCTGTTGTGAAGATATCCGCCAGCGCCGCGGAACACGATTTACACGCCATGTACAAAGTAAATGTTGAAGACCTGTCACAGCTGCTTGCATATCATGAGGTGTTTGGGAAGCTGAATGCAGCCGAGCAGGGACAACAGTCGCATGCAAAGGTTATAAGTGAAGTAGAAGTGGAAGCTGGCACAAGTACCACCGCAATGGCTGAAACCGATTCTTCAACGGGACATTCATGCGACCTCTGTGGGAAAACATTCCAATTTCGATATCAACTAATTGTCCATAGACGTTATCATGGCGAGAACAAACCCTTCACGTGCCAGGTGTGCGGATCAGCTTTTGCCAATCCTGTTGATCTATCGAGACATGGAAAATGCCATCTTGCCGGTGATCCATCAGAAAGGCAGGCGAAAAGGCTGTCTCAAGAGAAGCCCTACGCATGTACCACTTGCCACAAGAATTTCTCTCGGAAGGAGCACCTCGATAACCATGTGCGAAGTCACACTGGCGAAACTCCGTATAGGTGTGAATACTGCTCAAAAACATTCACTCGCAAGGAGCACATGGTCAATCACGTAAGGAAACACACGGGTGAAACGCCCCATCGTTGCGATCTGTGCAAGAAGAGCTTCACCAGGAAGGAGCACTTCATGAACCATGTCATGTGGCACACAGGTGAAACACCGCACCATTGCCAAATATGCGGCAAGAAGTATACTAGGAAGGACCACTTAGTGAATCACATGAGGTCGCATACAAACAATACACCGTTCCGATGCGACCTCTGCGGCAAGTCCTTCACGAGAAAGGAACACTTCACCAATCACATATTGTGGCATACCGGCGAAACGCCGCACCGGTGCGATTTTTGTTCGAAAACATTCACTCGCAAGGAGCACCTCTTAAACCACGTCAGGCAACACACCGGGGAATCCCCACATAGGTGCAACTATTGCTCCAAGTCGTTCACACGTCGAGAACATCTAATCAATCACATACGACAGCATACTGGAGAGACTCCATTCCAATGTGGATATTGTCCTAAAGCTTTCACTAGGAAGGATCATTTAGTGAACCATGTGAGGCAGCACACCGGGGAGTCCCCTCACAAGTGCTCGTACTGTACGAAGTCGTTTACTCGCAAGGAGCACCTCACGAACCACGTGCGCCAGCACACGGGCGAGTCTCCTCACCGCTGCTCGTACTGTGCGAAATCATTCACTCGGAAAGAGCACCTCAAGAATCATATCAGACAACACACGGGCGAGACGCCGCACGAGTGCCCGTATTGCACGCGCGCGTTCTCGCGCAAATCGCACCTCACCACCCACATCCGTCAGCACACCGGCGACACGCCGCATGCCTGTATCTACTGCGGCAAGAGTTTCACCAGGAAAGAGCATCTTGGTAACCACATACGACAGCACACGGGGGAGACGCCGTTCAAGTGCACGTACTGCTCGAAGGCGTTCTCGCGCAAGGAACACCTCAACAACCACGTGCACCTGCACACCGGCGAGACGCCTCACAAGTGCCCCTACTGCACCAAGACATTCTCCAGGAAGGAGCATTTGACCAATCATATCAGgATCCACACTGGCGAATCTCCACATCGGTGCGAATTTTGTCAGAAAACGTTCACGCGTAAAGAGCATTTGACGAATCATATGAAGCAACACACGGGTGACTCGACACACACGTGCAAGATGTGTTCTAAATCATTTACAAGGAAAGAACATTTGGTCACACATATGAGGTCGCACAGCTGCGGTGCGCGGCCGTACAGCTGCGGCGAGTGTGGCAAGTCGTTCCCGCTCAAGGGCAACCTACTGTTCCACGAGCGTTCGCACAACAAGGCTGGGGGTGGCGCACGCCGGTACCGCTGCGACGTCTGCTCCAAGGAGTTTTGGTGTAAAGGTCACTTGGTGTCCCACCGACGTACTCACGCGGAGTTAAATGAGGCAACCGGAAATACAGATGCGCCCGAAGAGACGGAGGATTTCACAGACTGCAGTAATAAGTGTATCAAAATGGAGATTGAGGTTCCATCTCTCGAAAGAAAATTAGAAACAAGGGACACATCAGAGAATAGGTCAGCAGAAAGCAACATAGTTCAAACACAAAATTCTCAAAGTGTTCCAACGAACACTACTGTTATGCAAATAACAAGTCAgCAAGTCCGTGCTAGCCCAACAACGAGCACCGCTGCAGTTGCGACGTTCACCCACTCGGCAACAGGGCAGCATCACACGGGCACTATTACACACCATCCTGTCACGGTTAATTACTAA
Protein Sequence
MNQEHHNLNTAGQPPGSAESQNQRVQAVQQQQSNLPPTTSPTDLRVNSAAVNVALSSVAKYWVFTNLFPGPIPQVSVYGLPAGTRIENGKPVQDISQGHASILNGDPNIILGHHGGQQQVTVTGPGNQQIPVTQIITTQSGQTHEALVGHSTQQELGGTGASQGPNANTHQVPTNRVEFVHHNIDMSHHSQHIMQQQLMATTRPDHSNQQIQLTVSEDGTVTVVEPGATKMVEKEEMHEAIKMPTDHTLTVHQLQQIVGQQVIDSVVRIEQATGEPANILVTHNPDGTTSIEASAVDPLIIKDEKAAPKMDATAQFAIPTDIKDIKGIDLKNVGAMGMEGAVVKISASAAEHDLHAMYKVNVEDLSQLLAYHEVFGKLNAAEQGQQSHAKVISEVEVEAGTSTTAMAETDSSTGHSCDLCGKTFQFRYQLIVHRRYHGENKPFTCQVCGSAFANPVDLSRHGKCHLAGDPSERQAKRLSQEKPYACTTCHKNFSRKEHLDNHVRSHTGETPYRCEYCSKTFTRKEHMVNHVRKHTGETPHRCDLCKKSFTRKEHFMNHVMWHTGETPHHCQICGKKYTRKDHLVNHMRSHTNNTPFRCDLCGKSFTRKEHFTNHILWHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCNYCSKSFTRREHLINHIRQHTGETPFQCGYCPKAFTRKDHLVNHVRQHTGESPHKCSYCTKSFTRKEHLTNHVRQHTGESPHRCSYCAKSFTRKEHLKNHIRQHTGETPHECPYCTRAFSRKSHLTTHIRQHTGDTPHACIYCGKSFTRKEHLGNHIRQHTGETPFKCTYCSKAFSRKEHLNNHVHLHTGETPHKCPYCTKTFSRKEHLTNHIRIHTGESPHRCEFCQKTFTRKEHLTNHMKQHTGDSTHTCKMCSKSFTRKEHLVTHMRSHSCGARPYSCGECGKSFPLKGNLLFHERSHNKAGGGARRYRCDVCSKEFWCKGHLVSHRRTHAELNEATGNTDAPEETEDFTDCSNKCIKMEIEVPSLERKLETRDTSENRSAESNIVQTQNSQSVPTNTTVMQITSQQVRASPTTSTAAVATFTHSATGQHHTGTITHHPVTVNY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01030446;
90% Identity
-
80% Identity
-