Basic Information

Insect: Macrosoma leucophasiata
Gene Symbol: -
Assembly: GCA_036365455.1
Location: JAWQUS010000017.1:17771523-17782185[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 7.3 6.1e+02 2.0 0.2 1 23 89 112 89 112 0.85

2 18 1.7 1.4e+02 4.0 0.1 3 23 117 137 115 137 0.95

3 18 0.061 5.1 8.5 0.2 2 23 141 163 140 163 0.95

4 18 0.003 0.25 12.6 0.6 2 23 392 414 391 414 0.96

5 18 0.072 6 8.3 0.0 1 19 422 440 422 442 0.96

6 18 0.013 1.1 10.6 1.4 3 23 454 474 453 474 0.97

7 18 5.7 4.7e+02 2.3 0.7 1 22 490 511 490 513 0.72

8 18 0.0034 0.28 12.5 4.5 1 23 522 545 522 545 0.95

9 18 0.028 2.3 9.6 1.3 2 22 619 639 618 641 0.85

10 18 6.9 5.7e+02 2.1 2.1 1 23 646 669 646 669 0.90

11 18 4.2e-05 0.0035 18.5 1.8 1 23 675 697 675 697 0.97

12 18 0.00012 0.0097 17.1 1.3 1 23 704 726 704 726 0.98

13 18 9.8e-05 0.0082 17.3 2.3 1 23 731 753 731 753 0.96

14 18 0.0027 0.23 12.8 2.5 1 23 759 781 759 781 0.98

15 18 2e-06 0.00017 22.6 1.4 1 23 787 809 787 809 0.98

16 18 0.0068 0.57 11.5 1.9 2 23 816 837 816 837 0.98

17 18 0.00097 0.08 14.2 0.7 2 23 846 868 845 868 0.97

18 18 0.25 21 6.6 0.0 1 23 873 897 873 897 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	7.3	6.1e+02	2.0	0.2	1	23	89	112	89	112	0.85
2	18	1.7	1.4e+02	4.0	0.1	3	23	117	137	115	137	0.95
3	18	0.061	5.1	8.5	0.2	2	23	141	163	140	163	0.95
4	18	0.003	0.25	12.6	0.6	2	23	392	414	391	414	0.96
5	18	0.072	6	8.3	0.0	1	19	422	440	422	442	0.96
6	18	0.013	1.1	10.6	1.4	3	23	454	474	453	474	0.97
7	18	5.7	4.7e+02	2.3	0.7	1	22	490	511	490	513	0.72
8	18	0.0034	0.28	12.5	4.5	1	23	522	545	522	545	0.95
9	18	0.028	2.3	9.6	1.3	2	22	619	639	618	641	0.85
10	18	6.9	5.7e+02	2.1	2.1	1	23	646	669	646	669	0.90
11	18	4.2e-05	0.0035	18.5	1.8	1	23	675	697	675	697	0.97
12	18	0.00012	0.0097	17.1	1.3	1	23	704	726	704	726	0.98
13	18	9.8e-05	0.0082	17.3	2.3	1	23	731	753	731	753	0.96
14	18	0.0027	0.23	12.8	2.5	1	23	759	781	759	781	0.98
15	18	2e-06	0.00017	22.6	1.4	1	23	787	809	787	809	0.98
16	18	0.0068	0.57	11.5	1.9	2	23	816	837	816	837	0.98
17	18	0.00097	0.08	14.2	0.7	2	23	846	868	845	868	0.97
18	18	0.25	21	6.6	0.0	1	23	873	897	873	897	0.94

Sequence Information

Coding Sequence: ATGTCATCCGAATCGGACGACGAACCGCTGTCTACATTAGCGGCAGCGAAAAAGGCGGATCCTAACAAGTTTGTAAACGACTGTGAATTTGAGATACAATTAGATGATAATGGACctaaaaagagtaaaaatactatACCACACAAAAACTTATCTGTGACTATAAAATTGGCACGGAAACTGAAGACTGGTGCTGGCCTTACGGTTATTGAGCGACCCACTGATGTGTGGCTGTACCTAAAAGATTTGAACCCCACTGGACCTTACAGCTGTTTGTTATGCTCGGACTGGTTCATAAATAGGTCCAAATTAATTGTTCATTACATTCTGAACCATAAAAAGGATTTTTGCGGGATTTGCAGATATTTTGTTCCCGACAGAGAGTTGTGGTGGTCCCATATCCAGTTTCACACACCCTGGCCATGTTCCCAATGTGTTGACACTTTCCCTTCAGAGACTCTGCTACGTCAACATTTAAATACCAGGCATCAATTAGTTCACTGTCGCCTCTGCCATTTCCGAGTACCTGCTGATGACCAGTACGATACGCATTTGCTTCATAAACACAATGTTACTAATGCAGCTAGTAAAGATGAAGAATTTCTTTGGGTATTTGAATATGAGGGTAGTGATCAATTTCACTGTCTTCTTTGCTCGAAGTCTGATAACCCAGTGAAATCATTCTTCAACCACTACATGTGCTTCCATCATTTTACTCTCAAATGCCTTACGAGCTTAATTTCTGGCAGAGATCTACCTTTCATTGTTAACGGTGCAGATGTCAGTTCACAATTTGTTAATGATCAGTTGATGGGACATACTCGATTTGGCTATGTTGATTTAGAAATGAAGCCTATTTTTAAACTAGATGGTGAGAACAAAGATTTGAACCAGATGCAGAATGTTGATGTCCAGATTATTAAAAAAGAGAATGTTAGTGACAATGAGGAAAGTAAATGTGATGACAATAATTCAAGTGAAAGCAGGAACGATGAAAATCAGGATTATAATGGTGAAGATGATTATGATACAACACAAACGGAATTAGTAATATTCCAGAAGTGTTATCTAGATTATGTTTCCGAATTGCTCAGTGATATTTCATCTAATTCAGTACCAGAAAATTCTGATATAAATTACGAGAATTTAAAATGTGATGTTGCAATAGATGTGGTTTGTAAATTTTGCAATGAGAAGTATGATAATGCCCAATCTTTTATTTCACATATGAATAAAATGCATGGTATAAAATCCGTACCAATTTATTCATGTCGAGTTTGTACAGCTACATTTGAGACTTTGGGAGAATTAGAGATTCATAGTGCCGAGGAGTTGGCAGATTTCGAAGATTTATGGTTGTGTCAGTTTTGTGACAAAGAATTTGATAACAGACAGGAAACTAGAAAACATTTGAATGAACATGTGGCTTTATTAGATCATGATAACTGCTTCAGTCCACATTTGGGTTTTAAGTGCAAATATTGTCCAAATCTGTTTTGGAATGAAACTGACCGAGAATCACATCAAGTAAAAGAacatttgaataaatatatagatCAATTCTATAAATGTAAGGAGTGTTCAGAGGCCTTCAGTGACAAGGTTTGGTACACACACCACCATTTTGTGAAGCATGCAAATGAAGAACATCCATATATGTTGAAATGTTGTCTTTGCTGTGTTGTGCTAGTCGGTGTGGACGAGATGAGGGAGCACTTTAAAGAGAAGCATCCAGAGGCTAAGAAAGTATTCTGCTCTCTAGATGGTTGTAACCACAAACCTCTGAGTCATCGGAAGTCATTGAAACTACACGTTAAGTCAATGCACTGCACAGCTGGCCAAGAGAAACCGGTGAAGTGCAAGTTGTGTGGCAAAGGATTCACCAGCAGTCGGGCTTGCAGGAACCACGCGGCGCAGGTCCACGGGCCCGGCAAGTACAAGTGCAAGTTGTGCAGGGAAGTTCTGCACACTATGGATGAGAGGAAACTGCACTACCTACTGCGTCACCCCGGCCGCCACCCGTTCGAGTGCTCGGAGTGCGGCAAGTCGTTCCAATACAAGTCGTCCCTGTACATGCACAAACAGGAGCACGTGCCCAATAAGAAGTGTTACACTTGCGATTACTGCGGGAAATCCTTCCTTAAAAAGGACTCGTTCCGTGAGCACGTGCAAATCCACGAGGGCCCGCGACATGCGTGCTCGTACTGTCCCATGCGCTTCGTGCAACGCTCCAACATGCTGCGTCACGAGCGCCGCCACACCGGCGAGCGGCCCTACGCCTGCGCACACTGTCCTCgcacttttgctgacaagggcgCCTGTACTTCACACACTAGGACTCATTCGAAGGATACCTCTTACGCATGTCTTTACTGCGGCCAGACATTCGTCCAGAAATCCAAACTGACTTATCACATACGCAAGCATACGGGAGAAAATTTGGAAACGTGCACGGTATGTTCGAAACTGTTCACAAGCGGGTGTGCGCTGCGTGAGCACATGAAGATACACGTCGCTAAGAAGAAGCAGACTGTCAAATGTCCGCTTTgcgACCGCAAGTACCAAGACGAACGTTACATGCTGCGTCACCTGCGCACATCTCATACGTCGGCGCAGTTCTCGTGCCCCGTGCCCGCCTGCCCGCGCCTCCTCGTCACGCCCGCCGCGCTCCGCCACCACGTGCTCACACACTCGCCCGTCAGCACCTTCCGGTGCAAATGCTGCCCGAAGTCCTACGCTTGCAAGAAGTCGATGGTCAAGCATCTACGAAGACGTCACGGCTTGAACGGCGCTCAGGTCAACATCAAAGAATTCTTTGACCGATTAGACCCGTGGGAGTGTCAAATTGAACTGGACGAAGCTACGATGACGAGCGTGTTTGGACCACCCAAGAAGAAAGTCAACGATATTCTGTTAGGAGACTTTGTGACTCTTGCGAACAAAATAAAACTCGTGCAAGAGAACATACAAAAGCAAATGAATGCCGCGGAAGAAGCGAAACAGCGACAAGAGAATCAGATACAAGAGAGTGAATATGTGAATGTAGATGGTGGGAGAGCCGTGGTTAAGGAAGAGTGTAAGAGTAGCGAAGATGAGTTGGAACCGACAGACTTTGTAAGTGTTAAGGTGGAACCGATGGATGATTATGAGGTGCAGTCGTGA
Protein Sequence: MSSESDDEPLSTLAAAKKADPNKFVNDCEFEIQLDDNGPKKSKNTIPHKNLSVTIKLARKLKTGAGLTVIERPTDVWLYLKDLNPTGPYSCLLCSDWFINRSKLIVHYILNHKKDFCGICRYFVPDRELWWSHIQFHTPWPCSQCVDTFPSETLLRQHLNTRHQLVHCRLCHFRVPADDQYDTHLLHKHNVTNAASKDEEFLWVFEYEGSDQFHCLLCSKSDNPVKSFFNHYMCFHHFTLKCLTSLISGRDLPFIVNGADVSSQFVNDQLMGHTRFGYVDLEMKPIFKLDGENKDLNQMQNVDVQIIKKENVSDNEESKCDDNNSSESRNDENQDYNGEDDYDTTQTELVIFQKCYLDYVSELLSDISSNSVPENSDINYENLKCDVAIDVVCKFCNEKYDNAQSFISHMNKMHGIKSVPIYSCRVCTATFETLGELEIHSAEELADFEDLWLCQFCDKEFDNRQETRKHLNEHVALLDHDNCFSPHLGFKCKYCPNLFWNETDRESHQVKEHLNKYIDQFYKCKECSEAFSDKVWYTHHHFVKHANEEHPYMLKCCLCCVVLVGVDEMREHFKEKHPEAKKVFCSLDGCNHKPLSHRKSLKLHVKSMHCTAGQEKPVKCKLCGKGFTSSRACRNHAAQVHGPGKYKCKLCREVLHTMDERKLHYLLRHPGRHPFECSECGKSFQYKSSLYMHKQEHVPNKKCYTCDYCGKSFLKKDSFREHVQIHEGPRHACSYCPMRFVQRSNMLRHERRHTGERPYACAHCPRTFADKGACTSHTRTHSKDTSYACLYCGQTFVQKSKLTYHIRKHTGENLETCTVCSKLFTSGCALREHMKIHVAKKKQTVKCPLCDRKYQDERYMLRHLRTSHTSAQFSCPVPACPRLLVTPAALRHHVLTHSPVSTFRCKCCPKSYACKKSMVKHLRRRHGLNGAQVNIKEFFDRLDPWECQIELDEATMTSVFGPPKKKVNDILLGDFVTLANKIKLVQENIQKQMNAAEEAKQRQENQIQESEYVNVDGGRAVVKEECKSSEDELEPTDFVSVKVEPMDDYEVQS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -