Mleu011097.1
Basic Information
- Insect
- Macrosoma leucophasiata
- Gene Symbol
- -
- Assembly
- GCA_036365455.1
- Location
- JAWQUS010000012.1:6109173-6110441[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 0.0012 0.1 13.9 0.2 1 23 64 87 64 87 0.93 2 10 0.32 27 6.2 0.9 2 23 114 136 113 136 0.94 3 10 0.01 0.85 11.0 3.4 2 23 159 180 158 180 0.97 4 10 3.7e-05 0.0031 18.6 0.1 1 23 184 206 184 206 0.98 5 10 0.085 7 8.1 3.1 1 15 211 225 211 234 0.79 6 10 3.8 3.2e+02 2.9 0.8 2 23 242 263 241 263 0.86 7 10 4.2e-06 0.00035 21.6 3.0 1 23 270 293 270 293 0.98 8 10 2.4e-05 0.002 19.2 2.5 1 23 299 321 299 321 0.98 9 10 3.7e-06 0.00031 21.8 1.2 1 23 327 349 327 349 0.98 10 10 2.1e-05 0.0017 19.4 4.9 1 23 355 378 355 378 0.98
Sequence Information
- Coding Sequence
- ATGATAGGTCTGAcatGTCCATCGTTAGTTATAAAGCAGGAAAAGCCTAATAAGAAACCGTCAGATCCCGATATATCCAAAATAAACAAACGAGAGCAAAAGGAAAGGAAAGCAAAGTTTTCAGATAACGTGAATCTTATACTGGAAAACTCTAACGCTACCTTGATCCGCTGCCACGGCTTGATTGGCTACACCTGTAGTTATTGTGACGATCAGTACCCGAATCCAGCCGATTTGAAGAAACATACTACCGAAGCACACGCTTCGGCCTTTAAATTCGAATGGGCAAAAGTGAGATATACCTTGGACTATATAGTGAAGCTCGACATTACTATGTTAGAATGCAATCTTTGTAAAACTAAAATGGATTCACTCGAACACCTAATCGACCATCTCACCAGTCAACACGGCAAAAATTATCACGGGGACACAAAGAACACCATCGTACCTTTCACGTTTGAAGGCAAAGAAATCAAATGCGTCGTTTGCTCCATGAAATTCAGAAGATTCAAAACGACCTTTCAACATATGAGGCGACATTACACAAACTATATATGTGACACTTGCGACATGGGATTCGTGAATCGGGGCAGCATGGTGAAGCATATGGAAACTCATAGATATGGCTCGTTCCCTTGTGACTACTGTGACAAAGTCTACGATACGCAGTCCAGGAAGAGATGTCACGAGAAATCGGTCCATGTTTACAAATCTAGAGTGAGCCGATGCGGGTATTGCAACATGCGCTTGCAGAAATATCAGAAGCAGGATCATTTGGCGCAAGTTCACGGTATAGTAACTGAAAAATATAAGTGTCAAGCGTGCGATAAATCATATAAAAGACGATCAACGTTATATTCACACATGAAGCGTGATCATTTGATGGAGAAGCGGCACAAGTGTGATTTGTGTGAGAAGACGTTCTATATGAAGAATGGTCTGAATAAACACATGCTGATTCACACGGGGATAAAAGATTTCGAGTGTGATGTTTGCTTGAAGTCGTTCGCTAGGAAGTATACTTTGAAGGAGCATAAGCGTATACATGATGATGATAGGAGATTCAAGTGTGAGCATTGTGGAATGGCGTTTGTACAGAAATGTAGCTGGCGGAGTCATATGCGCTCCAAGCATGGGGaggatgtttaa
- Protein Sequence
- MIGLTCPSLVIKQEKPNKKPSDPDISKINKREQKERKAKFSDNVNLILENSNATLIRCHGLIGYTCSYCDDQYPNPADLKKHTTEAHASAFKFEWAKVRYTLDYIVKLDITMLECNLCKTKMDSLEHLIDHLTSQHGKNYHGDTKNTIVPFTFEGKEIKCVVCSMKFRRFKTTFQHMRRHYTNYICDTCDMGFVNRGSMVKHMETHRYGSFPCDYCDKVYDTQSRKRCHEKSVHVYKSRVSRCGYCNMRLQKYQKQDHLAQVHGIVTEKYKCQACDKSYKRRSTLYSHMKRDHLMEKRHKCDLCEKTFYMKNGLNKHMLIHTGIKDFECDVCLKSFARKYTLKEHKRIHDDDRRFKCEHCGMAFVQKCSWRSHMRSKHGEDV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00943159;
- 90% Identity
- -
- 80% Identity
- -