Basic Information

Insect: Macrosoma leucophasiata
Gene Symbol: Ctcfl
Assembly: GCA_036365455.1
Location: JAWQUS010000008.1:15242636-15250613[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.017 1.4 10.3 5.8 1 23 178 200 178 200 0.98

2 11 8.2e-05 0.0068 17.6 1.1 1 23 206 228 206 228 0.98

3 11 7.4e-05 0.0062 17.7 1.6 1 23 234 257 234 257 0.96

4 11 0.037 3.1 9.2 3.2 1 21 263 283 263 285 0.95

5 11 0.00012 0.0098 17.1 2.7 1 23 291 313 291 313 0.99

6 11 3.3e-05 0.0027 18.8 5.5 1 23 319 341 319 341 0.98

7 11 0.0018 0.15 13.3 0.5 1 23 349 372 349 372 0.97

8 11 0.0057 0.48 11.8 4.5 2 23 379 400 378 400 0.96

9 11 0.00026 0.022 16.0 2.4 1 23 406 428 406 428 0.99

10 11 3.8e-06 0.00032 21.8 1.5 1 23 434 457 434 457 0.96

11 11 6.8e-05 0.0056 17.8 4.5 1 23 471 493 471 493 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.017	1.4	10.3	5.8	1	23	178	200	178	200	0.98
2	11	8.2e-05	0.0068	17.6	1.1	1	23	206	228	206	228	0.98
3	11	7.4e-05	0.0062	17.7	1.6	1	23	234	257	234	257	0.96
4	11	0.037	3.1	9.2	3.2	1	21	263	283	263	285	0.95
5	11	0.00012	0.0098	17.1	2.7	1	23	291	313	291	313	0.99
6	11	3.3e-05	0.0027	18.8	5.5	1	23	319	341	319	341	0.98
7	11	0.0018	0.15	13.3	0.5	1	23	349	372	349	372	0.97
8	11	0.0057	0.48	11.8	4.5	2	23	379	400	378	400	0.96
9	11	0.00026	0.022	16.0	2.4	1	23	406	428	406	428	0.99
10	11	3.8e-06	0.00032	21.8	1.5	1	23	434	457	434	457	0.96
11	11	6.8e-05	0.0056	17.8	4.5	1	23	471	493	471	493	0.97

Sequence Information

Coding Sequence: ATGCCACCTCCTGAtatgaaaattgataaaaatcgAATAATACAATCGTATTTAGACTCATACGATCCACAAGATACATTTCATGATGAACAAAATGAAACAACAACTGTTATTGCagTCAATAGTAATGGAGATGACGAGTCTGAAACAGGAGTCACATACTTTGTTGATGAAGAAGGCAGGTACTACTACCAGTCCGCCAACGATGGACAAAATCTTGTATCGCTTCCTACTCAAGTCTCGGAGACAACTGagGGCTTGGTAGAGGCCGACGCGCAGATGCTGGTGGATGGAAATGGGTATCAAACAGTAACGCTGGTCCCCTCCGAGTCGAGTTCTGGCGAAGTTAGCTATGTGCTTGTAGTGCAAGAGGAATCCAAGCCAGTGGTCAACATTGACATCAAAGTTGATAAGGATGACAAGGACAATGATGTGTATGATTTTGAAGATGAAGAAGGTGAAGTGAGCGAGAGCGACGATCCAGCTGCTAAGccAAAGGCCAAGCGAAGTGGAAAGTATACACGTCCAAACTTCACATGCAATTTCTGTTCCTATAATAGTCACCGGAGatATCTTCTTTTGCGTCACATGAAATCGCATTCGGAGGATCGGCCCCATAAGTGCAGTGTTTGCGAGCGAGGATTCAAAACTATCGCTTCCTTGCAAAACCATGTTAACATGCACAATGGAATTAAACCACATGTCTGCAAATACTGCAACAGTCCTTTCACAACATCAGGTGAACTGGTGAGACACGTGCGGTACCGGCACACCCATGAAAAGCCGCACAAGTGCTCTGAATGTGATTATGCCTCTGTGGAGCTGTCAAAGTTGCGTCGTCATGTCCGTTGCCATACCGGCGAACGTCCTTATCAGTGTCCACACTGCACCTACGCGTCGCCGGACACCTTCAAACTAAAACGCCATCTACGCACGCACACTGGAGAGAAACCGTACAAATGTGAACATTGCAATATGTGCTTCACTCAATCCAACTCCCTGAAAGCACATAAACTTATACACAATGTATCCGAGAAGCCAGTGTATGCTTGTGAATTATGCCCGGCAAAATGCGGCCGTAAAACGGATCTACGAATTCACATTCAGAAGTTGCACACTTCTGACAAACCCCTCAAGTGTAAGAGATGCGGAAAATCCTTCCCTGATCGGTACTCGTGCAAGGTGCACAATAAAACACATGAAGGTGAGAAATGTTACAAATGTGAACTGTGTCCATACGCGTCCACCACTATGCGTCATCTCAAGTCGCACATGTTGAAGCATACCGACGAAAAGCCATTTGTTTGCGAATTGTGTGATCAGTCGTTCAGgcAAAAGCAATTGCTACGGCGCCACCAAAACCTATACCACAATCCGACGTACGTGCCGAAGCCGCCCAAAGAGAAGACGCATACTTGCCGCGAATGCAACCGGCACTTCGCCCACAAGGGAAACCTTATCCGGCATCTCGCCGTGCACGACCCCGACTCTGGTCACCAGGAGCGGGCGCTTGCCCTCAAACTTGGCCGCCAGAGGAAGGTCAAGATTCTCGATGCCCAAATGAAGGATGTCGAGATGGAAGATTCAGACGACGAAGATAGTGACATAATAAAGCTAGGACTCGACGATGATGACGTGAAGCGCGGTAAGCTGGTGACGGTGGCTGACGGCGACGGCCAGCAGTACGTGGTGCTGGAAGTGATACAGTTGGAGGACGGGACCGAGCAGCAGGTCGCAGTCGTGGCACCAGATTTCATTGAGGAAGAGGAACAAGaaGAAGAGGAGGAAGAGATTGTTTTGCCTGACATCGATCACGCACGGTTGAATAGTGATAAGGAATCGACACAACTAAAAGCAACTGATCGAAGCATAAAACTTGAGAAGGATGTCGATACCTGTTTCGGCTTTGACgaAGATGACGAAGGtgatgaagaagaagaaatttCAAGTTACAACGATAAAGTTGTACTTCGTATTGCTTAA
Protein Sequence: MPPPDMKIDKNRIIQSYLDSYDPQDTFHDEQNETTTVIAVNSNGDDESETGVTYFVDEEGRYYYQSANDGQNLVSLPTQVSETTEGLVEADAQMLVDGNGYQTVTLVPSESSSGEVSYVLVVQEESKPVVNIDIKVDKDDKDNDVYDFEDEEGEVSESDDPAAKPKAKRSGKYTRPNFTCNFCSYNSHRRYLLLRHMKSHSEDRPHKCSVCERGFKTIASLQNHVNMHNGIKPHVCKYCNSPFTTSGELVRHVRYRHTHEKPHKCSECDYASVELSKLRRHVRCHTGERPYQCPHCTYASPDTFKLKRHLRTHTGEKPYKCEHCNMCFTQSNSLKAHKLIHNVSEKPVYACELCPAKCGRKTDLRIHIQKLHTSDKPLKCKRCGKSFPDRYSCKVHNKTHEGEKCYKCELCPYASTTMRHLKSHMLKHTDEKPFVCELCDQSFRQKQLLRRHQNLYHNPTYVPKPPKEKTHTCRECNRHFAHKGNLIRHLAVHDPDSGHQERALALKLGRQRKVKILDAQMKDVEMEDSDDEDSDIIKLGLDDDDVKRGKLVTVADGDGQQYVVLEVIQLEDGTEQQVAVVAPDFIEEEEQEEEEEEIVLPDIDHARLNSDKESTQLKATDRSIKLEKDVDTCFGFDEDDEGDEEEEISSYNDKVVLRIA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -