Basic Information

Insect: Macrosoma leucophasiata
Gene Symbol: -
Assembly: GCA_036365455.1
Location: JAWQUS010000024.1:16820848-16823635[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 3.9e-06 0.00033 21.7 2.4 1 23 197 219 197 219 0.98

2 11 0.11 9.2 7.7 6.8 1 23 227 249 227 250 0.94

3 11 0.00044 0.036 15.3 2.2 1 23 259 281 259 281 0.98

4 11 0.00027 0.023 15.9 2.6 1 23 288 310 288 310 0.97

5 11 0.78 65 5.0 2.5 1 23 316 338 316 338 0.94

6 11 8.1e-06 0.00067 20.7 2.8 1 23 344 367 344 367 0.96

7 11 0.012 0.96 10.8 1.9 2 23 373 392 372 392 0.96

8 11 3.2e-07 2.7e-05 25.1 1.9 1 23 398 420 398 420 0.98

9 11 5e-06 0.00042 21.4 2.2 1 23 426 448 426 448 0.99

10 11 0.00018 0.015 16.5 0.3 1 23 454 477 454 477 0.96

11 11 0.023 1.9 9.9 1.0 1 21 483 503 483 504 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	3.9e-06	0.00033	21.7	2.4	1	23	197	219	197	219	0.98
2	11	0.11	9.2	7.7	6.8	1	23	227	249	227	250	0.94
3	11	0.00044	0.036	15.3	2.2	1	23	259	281	259	281	0.98
4	11	0.00027	0.023	15.9	2.6	1	23	288	310	288	310	0.97
5	11	0.78	65	5.0	2.5	1	23	316	338	316	338	0.94
6	11	8.1e-06	0.00067	20.7	2.8	1	23	344	367	344	367	0.96
7	11	0.012	0.96	10.8	1.9	2	23	373	392	372	392	0.96
8	11	3.2e-07	2.7e-05	25.1	1.9	1	23	398	420	398	420	0.98
9	11	5e-06	0.00042	21.4	2.2	1	23	426	448	426	448	0.99
10	11	0.00018	0.015	16.5	0.3	1	23	454	477	454	477	0.96
11	11	0.023	1.9	9.9	1.0	1	21	483	503	483	504	0.93

Sequence Information

Coding Sequence: ATGGCTAACGTAAAAACTAGGCTGAAAGCTCACAAAAATGACACAGCCAAGGGGCGTggtaagaataagaataaaaaatcatcaacaGGTCCCAAAAATGAACACAAAGCGGAGAAGATGAAACGGCCCAATTTAAGGCCAAAAACAGTTGAAGACAATGTAAGATACATGTTAAAAAATGGTTGCAGATATCAAGACAGGGAAAAAACTGTAAAGACTAAAAGATTGAAACCAATATTTCCTCACGAAAGTATAATATTGAGAAATGGTCTTATAAGACACAAGAACAAGAAAAAATTGCAGCTCATTGATGACATACTGAAAAGTGAATTGATGATAGCAGATGATGGTAATAATCAGAAGAagcatacaaaacaaaataaaaataataatgcaaataaaagTCAAAGTAAGAGTTTAAATAACAATCAAGCTGGAATAAGTGATCAGAATGTGTCCGATTTAACTCCAGATTCCAATATCAATGAAACTAATAAGGACCAAATATACGAACAGAAAAGATTGCAAGCTTACGAGAAAATAATCAGTTTGAAAAAACGTAAACCAAAGACCCGAAAgcgaaaaatatacatttgtgATTATTGTAATAACACATTTACAAGAAAGGCATCATTGACAAGACATATTCACGTTCATCTGAACTTGCATCCGAATAAACATGCATGTAAGTTCTGTAAAAGTAGGTTCAGCAAACGTCTATACTTGACCATCCATATAAAGAGACATCATCCAGAGGCCCAAGGACCTAAGCATTACATATGCAATACATGCCATAAGCCGTTCCTATTGAAAGAAAATCTGAAAATGCACATGTTGACCCATAGGAATGAGGCACATATCTACCGTTGCTACTACTGTGAAAAAGTTTGCACCAAACAAGCATTATTAATTCGGCACGAGAAAGAGCATCTGGTTAACGGTAAATATTACTGCaccgtttgtaatattaagttTGAGTGTCGCAACAGACTTCTGATGCATATAAAGGGACATATACAGATGAAAGAATTCATCTGTCCGCACTGTGGTAAAGAATTTGTGAGACTCAATTCAATGAAGCGTCACATACAAATATGCCATGGTGGCCATCGCATACAGTGTCCTATATGCAAGAAATATTTGAAAGGTCATTTGACTGAGCATATGCGTACACACGAGAATGCACGTCCCCACGAGTGTCCAGATTGCGGACAAAAGTTCACACAATCTACACAGCTGAATGTCCACCGTCGCTCCCACACCGGTGCCAGACCGTACAAATGTAGGATCTGTCAGCGTGCATTCTCTCACTCTAATGCCTTGATGTTGCATATTAGAAGGCATACCGGAGAAAAACCGTTTGTATGTGCAATGTGTCCCCTAACATTCTCACAGCTACCGCACATGAAGGCCCACATGCTCAACATACATGGGAAGGTGAAACCATATAAATGTGAGAAATGCAAAGAATTCTTCAAGCTAAAAGCTGATATCATGAATCATTCCAAGACATGCACAGTGGGGGAGCGTGTCCTGTCCTTTGAGGAGAAAATCCAAAAGTCAGTTCAAATTGAGGAGATTGAAGTGGAAACAGTCATGAGTCTCTCCAGAATGAGATACCTGCTGGCCCTTCTTCTCACCATGATTGCCACTAAAGAGAAACTTAAGTATTTAGgATTCAACAAGCGACTCATAGATGATCTGCTTGAGGAATCGCTGGAGGCAATGGGTCACAAGCCATGTGAGGATGAGACATTGAAACCATTTGCTCGTCTCCGGGCAAACATTGCGATATTGCTGAAAGGTACTGTACCGCAGGATCAAATGAAAAAATTTcaagaagaaaataaaactacAGAGGAATTATTAGAACTGTtgacaaatgagaaaaaaaagagtaattAA
Protein Sequence: MANVKTRLKAHKNDTAKGRGKNKNKKSSTGPKNEHKAEKMKRPNLRPKTVEDNVRYMLKNGCRYQDREKTVKTKRLKPIFPHESIILRNGLIRHKNKKKLQLIDDILKSELMIADDGNNQKKHTKQNKNNNANKSQSKSLNNNQAGISDQNVSDLTPDSNINETNKDQIYEQKRLQAYEKIISLKKRKPKTRKRKIYICDYCNNTFTRKASLTRHIHVHLNLHPNKHACKFCKSRFSKRLYLTIHIKRHHPEAQGPKHYICNTCHKPFLLKENLKMHMLTHRNEAHIYRCYYCEKVCTKQALLIRHEKEHLVNGKYYCTVCNIKFECRNRLLMHIKGHIQMKEFICPHCGKEFVRLNSMKRHIQICHGGHRIQCPICKKYLKGHLTEHMRTHENARPHECPDCGQKFTQSTQLNVHRRSHTGARPYKCRICQRAFSHSNALMLHIRRHTGEKPFVCAMCPLTFSQLPHMKAHMLNIHGKVKPYKCEKCKEFFKLKADIMNHSKTCTVGERVLSFEEKIQKSVQIEEIEVETVMSLSRMRYLLALLLTMIATKEKLKYLGFNKRLIDDLLEESLEAMGHKPCEDETLKPFARLRANIAILLKGTVPQDQMKKFQEENKTTEELLELLTNEKKKSN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -