Mleu016916.1
Basic Information
- Insect
- Macrosoma leucophasiata
- Gene Symbol
- ZFX
- Assembly
- GCA_036365455.1
- Location
- JAWQUS010000020.1:622894-624288[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 0.00015 0.012 16.7 2.8 2 23 151 172 150 172 0.98 2 10 7e-07 5.9e-05 24.1 0.8 1 23 178 201 178 201 0.97 3 10 5.6e-06 0.00046 21.2 0.6 1 23 210 232 210 232 0.98 4 10 0.00054 0.045 15.0 2.7 1 23 238 260 238 260 0.98 5 10 0.00014 0.011 16.9 5.4 1 23 266 288 266 288 0.95 6 10 3.9e-07 3.3e-05 24.9 1.1 1 23 294 316 294 316 0.98 7 10 3.1e-07 2.5e-05 25.2 1.4 1 23 322 345 322 345 0.96 8 10 0.16 13 7.2 0.3 2 23 376 398 375 398 0.93 9 10 1.9 1.6e+02 3.8 0.2 1 17 404 422 404 429 0.81 10 10 0.00066 0.055 14.7 0.9 1 23 435 458 435 458 0.92
Sequence Information
- Coding Sequence
- ATGGATCAAAAGATCTGTCGTATTTGCTGCGATAAAGACGGTAATATCTATTTATTCGACACAAGTGATAGTCTTCAAATCAGCGCCAAAATTATGTATTGCTGTGCGTCCATAAGTATAGTGAAAGACGACGGATTGCCAACATACATCTGTGAACAGTGCCATACTGAGTTGGAGGCTTCCTATCGCTTTGTGTTGAAGTGTGAAGACGCGGACAAGAAACTAAGAGCTCCACAATACGTACAGAAAAAGCACGACGATATCAATATGAAATTAGAAGTGAAGTCTGAAGACTTCGACAATTATAGTTTAGACGGCTCCGTCGATGACTGCACGCCTATAAACGACCTAAAATCTGAGTTAAAATTGGAGAATACTAAGGAGGATTACTTAAAACAGAAAGATAACTTCAAGAGTCGaagaaaaaaaagcaaaaacaatggTCCGAAGAAGTGCAATGTTTGTAGCAGAGTGTGCGCAAACACCTCGACATTTATCATACATATGCGCACCCATACTAACGAGAAACCCTATCCATGTCCATCTTGCGATAAAAGGTACAAAGATAGAGGTAGTTTAAAACGGCACATGGAGAGGAACCATCTTAAAGATAAAAGAACGCGAAACTTTATCTGTGAGCTTTGTGGTAAAggctttttttcaaaaactgatGTAAAAACACACATGAGAATTCACACTGGAGAGACTCCATATGCTTGTTCTGTATGTCCTAGTAGGTTCTCACAGTTATGTACCTTGCTGCGTCACCAGAAGAGACATACTGGAGAACGATCTCACATGTGTACAATTTGCAACAAAAAATTCTGCACCAAAGAAGAACTGAAGACTCATAACTTAGTTCATAGTAACGAGAAGAGATACTCTTGCCCACTTTGTAATATACCatttaaatatagaaataatttaaagaaacatatcAGATCACATTCCGAGCCTAATAGCTTTGTTTGTAATCATTGTGGAAAGACATTCAATGTTAAAGGCAATTTGAAAGTTCATATAGACCGACAGCACTCTTCGAAATCAGGCTTCTGTAATTTATGTTCTAAGTATGTTGCGAATATTGAGGCTCATACATGGCGGCACACTGGTGAACGTCCACTGAAATGTGAGCTATGTGCTAGCAGCTTCTTTGCACAGCGAGCATTGGCCAGACATATCAATTTTCGAcacaaacagacggacaaatTTAAATGTACAGTTGAAGGTTGCAAGGTTGCATTTCCTTCACAGCCGATGTTGGACTTTCATACGGCTAAATTACATGGTACTGTCATACCATACCCCTGTGATAGATGTTCTAGGGGTTTCTATAGAAAGAATGATTTGTCTCGACATAAAATTGGTACacataaagaaaaattagacttataa
- Protein Sequence
- MDQKICRICCDKDGNIYLFDTSDSLQISAKIMYCCASISIVKDDGLPTYICEQCHTELEASYRFVLKCEDADKKLRAPQYVQKKHDDINMKLEVKSEDFDNYSLDGSVDDCTPINDLKSELKLENTKEDYLKQKDNFKSRRKKSKNNGPKKCNVCSRVCANTSTFIIHMRTHTNEKPYPCPSCDKRYKDRGSLKRHMERNHLKDKRTRNFICELCGKGFFSKTDVKTHMRIHTGETPYACSVCPSRFSQLCTLLRHQKRHTGERSHMCTICNKKFCTKEELKTHNLVHSNEKRYSCPLCNIPFKYRNNLKKHIRSHSEPNSFVCNHCGKTFNVKGNLKVHIDRQHSSKSGFCNLCSKYVANIEAHTWRHTGERPLKCELCASSFFAQRALARHINFRHKQTDKFKCTVEGCKVAFPSQPMLDFHTAKLHGTVIPYPCDRCSRGFYRKNDLSRHKIGTHKEKLDL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -