Mleu011063.1
Basic Information
- Insect
- Macrosoma leucophasiata
- Gene Symbol
- -
- Assembly
- GCA_036365455.1
- Location
- JAWQUS010000012.1:5892097-5903141[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 25 0.017 1.4 10.2 1.6 1 23 126 148 126 148 0.93 2 25 0.0016 0.13 13.5 0.2 3 23 175 196 173 196 0.96 3 25 0.006 0.5 11.7 0.7 1 23 218 240 218 240 0.98 4 25 0.13 11 7.4 1.3 1 23 244 266 244 266 0.85 5 25 0.011 0.89 10.9 0.8 1 23 270 293 270 293 0.95 6 25 1.7 1.4e+02 4.0 5.9 2 23 300 322 299 322 0.96 7 25 0.054 4.5 8.7 0.1 3 23 331 352 329 352 0.92 8 25 0.00091 0.076 14.3 3.8 1 23 358 380 358 380 0.97 9 25 0.00028 0.024 15.9 1.6 1 21 386 406 386 407 0.94 10 25 2.1 1.7e+02 3.7 0.4 1 23 444 466 444 466 0.94 11 25 0.93 77 4.8 0.4 2 23 495 517 494 517 0.94 12 25 0.026 2.2 9.7 0.3 2 23 538 560 537 560 0.94 13 25 0.00079 0.065 14.5 2.2 2 23 566 588 565 588 0.95 14 25 0.0042 0.35 12.2 1.2 1 23 593 616 593 616 0.95 15 25 0.16 13 7.2 0.3 2 23 619 641 618 641 0.95 16 25 0.1 8.6 7.8 1.8 2 22 648 668 647 668 0.94 17 25 0.0069 0.58 11.5 0.5 1 23 726 749 726 749 0.93 18 25 0.8 66 5.0 0.1 3 23 778 799 776 799 0.92 19 25 0.5 42 5.6 0.2 3 23 823 845 822 845 0.93 20 25 0.00076 0.063 14.5 0.6 3 20 852 869 850 873 0.90 21 25 0.13 11 7.5 0.4 1 23 878 901 878 901 0.97 22 25 0.00051 0.042 15.1 0.2 2 23 907 929 907 929 0.94 23 25 0.00012 0.01 17.0 4.7 1 23 933 956 933 956 0.97 24 25 0.00063 0.053 14.8 0.6 2 23 963 984 962 984 0.96 25 25 0.0016 0.14 13.5 2.1 1 23 990 1012 990 1012 0.97
Sequence Information
- Coding Sequence
- ATGAAAGCCGAGCTGGAAGGGCCACCTGTCGAGGAACCAGAGATTGAATATTTGGAGGAGGACATCGATTTTGATGATGACGACCTGAAGGAATCCGAAGAACTAACCTCGGAGGACATCACAGTGACCGCCCTCCCTGTAAAAGGGAAGCGCGGGCGGCCCAAGAAGACCGTGAAGCCTGAGAAGAAAACGAAAATAGCTAAAGTGGAGGAGAAGCCGCGGTCTTCGAAGGCGGTCGTCAAAGGTGACGACCAAACCGAGGCAAGGAGTAAGTCCTCGTTGACAGCAACAAAACGCAATCGCATCATGAAAAGGAACGCGATTATCGTTCTAGAATCATCCACGGTCGTCCCATTCAAATGGCACAGGCATAACTACTTATGCTTCTTCTGTTTCCAAACATTCAAAGACGTAGACGCACTGAAAAAGCATACAAGCGAACACAAAAAACCGAATATCAAAGGAGCCGTGTCGTACTTAAAAAGGGATGAGAAAGTGAAAATTGACATCACTTTGACGGCTTGTAGAATTTGTGACAGAAAACTTGATACATTCGACGCTTTGATACGTCACATTAAAACTGCCCATAAGAAAATCCTCGCTGATGAATACGGTTACGGAGTAATTCCGTACAGATTGCATAGAGATACATACCAATGTGCGATCTGCAGTGAAAACTTTCAGTACTTCATCAAATTGAACCAACATATGAACGAGCATTACGGGAATTATATTTGCGAGTTATGCGGCAAATCCTTTCTGAGTCAAGACAGGTTACGCTGTCATGCCTTAAGCCACGGCGCCGGTTTTCGTTGCAACTTGTGCCCAGAGACATTCGACTCCCTAACGCAAAAGAACGCGCACAAATCCAAAATACACAACACAGAAAAGACTATCCAATGCTTCTTCTGCACTCAGACATTCCAGAACTATACTCAAAGGAAGCGGCATCACAGCACATCGCACGATATACCCCTACCCGCGGTGAACTGTCCAGCTTGTGACAAAGCTTTTGAGATACCCAGCAAGATGCGAGCGCATTTTAAGGAGGTGCACCTTCGGGAGAAGAATTTCGCCTGTTCCATGTGCGACCAAAAGTTCTTCTCGAGGACCCACGTTCAGAAACACATGATAAAGCACATGGGAGAAAGGATACATGAGTGCGAGGTTTGCAAGAAGTCGTACGCAAGGAAACAGACGTTGAGAGATCATATGCATTTAAAACCGAGGAAGTACAATGGGTGTGAGGCCTCCTCGATGCGAAGGCGGAGGAATCTGCAGATATTGTTCAACAACACCACAATAATACCGTTTAAGTGGCGCGGGAAGTATTTATGCTTCTTTTGCAGCAAATTCGTGGCTGAATATCCTGAACTAAGAGAGCATACGAAGGCTCACGGAGTCTGTTCCACCAACGATCATTCCTTGAAAGTGTTAAAAGGCGGGCCGAATATGGAAATTAAGTTGGATGTATCGGACATTACCTGCGAATTGTGCCGCGAACTGTTCCCTACATTTGATGATATCATCAATCATTTGCACGTTAAACACAAAATCGAGTACGATAAAAACGTGGATATGGCTATAAAGGAATACAAACTCGACGACCTCAGCTGCTTGGTGTGCAACGAGAAATTTTCCTACTTCGGCTACTTAGTGTCCCACGTCAACAATAATCACCCAAAGAATTGCCTGATTTGCGACAAGTGCAAtcaaaagtttaataaaaagcgAGACTTGTTCACGCACATCAAGAATTATCATCGCGAAGGCGGGTATAAGTGTGAGTTGTGTCCGCAGAGTTTCAGCTCACTAAACATACTAAGGAAACATCGGAGTAATCGCCATTTGACTAGTTGTAATATCTGCCAATTGAAACTACCCTCGGCtgctttaaaacaaaaacatatgaAGCTCGAACATCCTGATGACGGTTCTTTACAATGCGACAACTGCTACAAAGATTTCCACACAAAATTAGGTTTGAAGATGCACACGAGGAAATGTAAAGGAGATTTTTCCGAgttcacaataaaaaaagaagaatatgATGCAATGGACTTGGATGAGAGTTATGAAGAAATAAAACGGCCCAGTGTCAAGCAGATTAGAGAAAACATTGTCACTGTTATAAACATGTCTACAGCTATACCTTTCAACTTCTACAAGAATAAATTCAACTGCTTTTACTGCTCCAAAGACTTCCCCGACTCAGATCTGATGAGAGAGCACACCGTCATGGAACACCCAATATGCGATGTTGAAGAGAAATGTATTAGGAAATGTCGAGAATCGGTTGCGTGCGTCAAAATCGATATATCGTCCCTAGCTTGCAAGATTTGCTTCGAATCGATGAGTGATTTGGAGTTATTAATCGATCATTTGATATTGAAACATCAGGCGAATTACGATAAATCGATAACCACATGCCTTCAGCCGTACAGGCTTATAAAGGACCACATGGCTTGTCCGAGTTGTCCAGCCGAAGTGTTCCGCTTCTTTGGTACATTACTCAAGCATATGAACCAAAAACATacgaataataacataatttgtgTATACTGTGGTCAGACTTTTAGACGAGATCAGAATTTAAGGGTGCATATTTGGCGGCATCATAGAGATGGTAGATTTAAATGTAGTATTTGCGAAGCGGAGTGCAATATACCTTCAAGGTTATATATGCATATGGCGAAGGCGCACGGTGTGAAAGCGGCGAAATGTCCAAAATGTCCTGAATCGTTTGCAACTCAGTATCTACGgcaaaaacatttgattgagGCCCACGATTCGGGTCACAAGTGTAACTATTGCGGCAAGTTATTCACAAGGAACTCATTTATGAGAGACCACGTGAGACGGACGCATTTGAAAGAGAAGAATGTGGAATGTTCTATATGCAGTATGAAGTTTTTCAACAATATACTGCTGAGGCGACATATGGTCAAACATAGTGGGGAGAAGAATTTCCATTGTGATATATGCGGCGAAAGGTTTTATTGGCGGAAGAGTTTGCGCACGCACATGGCTAGGCATAGCAAGCATATTAATCCAATATAG
- Protein Sequence
- MKAELEGPPVEEPEIEYLEEDIDFDDDDLKESEELTSEDITVTALPVKGKRGRPKKTVKPEKKTKIAKVEEKPRSSKAVVKGDDQTEARSKSSLTATKRNRIMKRNAIIVLESSTVVPFKWHRHNYLCFFCFQTFKDVDALKKHTSEHKKPNIKGAVSYLKRDEKVKIDITLTACRICDRKLDTFDALIRHIKTAHKKILADEYGYGVIPYRLHRDTYQCAICSENFQYFIKLNQHMNEHYGNYICELCGKSFLSQDRLRCHALSHGAGFRCNLCPETFDSLTQKNAHKSKIHNTEKTIQCFFCTQTFQNYTQRKRHHSTSHDIPLPAVNCPACDKAFEIPSKMRAHFKEVHLREKNFACSMCDQKFFSRTHVQKHMIKHMGERIHECEVCKKSYARKQTLRDHMHLKPRKYNGCEASSMRRRRNLQILFNNTTIIPFKWRGKYLCFFCSKFVAEYPELREHTKAHGVCSTNDHSLKVLKGGPNMEIKLDVSDITCELCRELFPTFDDIINHLHVKHKIEYDKNVDMAIKEYKLDDLSCLVCNEKFSYFGYLVSHVNNNHPKNCLICDKCNQKFNKKRDLFTHIKNYHREGGYKCELCPQSFSSLNILRKHRSNRHLTSCNICQLKLPSAALKQKHMKLEHPDDGSLQCDNCYKDFHTKLGLKMHTRKCKGDFSEFTIKKEEYDAMDLDESYEEIKRPSVKQIRENIVTVINMSTAIPFNFYKNKFNCFYCSKDFPDSDLMREHTVMEHPICDVEEKCIRKCRESVACVKIDISSLACKICFESMSDLELLIDHLILKHQANYDKSITTCLQPYRLIKDHMACPSCPAEVFRFFGTLLKHMNQKHTNNNIICVYCGQTFRRDQNLRVHIWRHHRDGRFKCSICEAECNIPSRLYMHMAKAHGVKAAKCPKCPESFATQYLRQKHLIEAHDSGHKCNYCGKLFTRNSFMRDHVRRTHLKEKNVECSICSMKFFNNILLRRHMVKHSGEKNFHCDICGERFYWRKSLRTHMARHSKHINPI
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -