Mleu004939.1
Basic Information
- Insect
- Macrosoma leucophasiata
- Gene Symbol
- Zfa
- Assembly
- GCA_036365455.1
- Location
- JAWQUS010000006.1:2962078-3000147[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 19 3.5 2.9e+02 3.0 0.0 7 23 28 44 28 44 0.95 2 19 0.01 0.83 11.0 3.3 1 23 49 72 49 72 0.98 3 19 0.00011 0.0088 17.2 2.4 1 23 78 100 78 100 0.99 4 19 0.031 2.6 9.5 1.2 1 23 106 129 106 129 0.97 5 19 0.0014 0.11 13.7 2.3 1 23 138 160 138 160 0.98 6 19 0.00034 0.028 15.6 0.7 3 23 168 188 167 188 0.99 7 19 0.00093 0.077 14.2 6.4 1 23 194 217 194 217 0.96 8 19 8.9e-05 0.0074 17.4 1.9 2 23 223 245 222 245 0.96 9 19 0.035 2.9 9.3 0.0 1 21 251 271 251 272 0.93 10 19 0.00055 0.046 15.0 1.6 1 23 518 540 518 540 0.98 11 19 7.7 6.4e+02 1.9 3.1 1 23 547 569 547 569 0.94 12 19 1.6e-06 0.00013 22.9 0.6 1 23 603 626 603 626 0.95 13 19 0.0004 0.033 15.4 0.5 3 23 634 655 633 655 0.96 14 19 0.00083 0.069 14.4 3.5 1 23 667 689 667 689 0.96 15 19 8.1e-06 0.00067 20.7 0.4 1 22 695 716 695 720 0.94 16 19 0.00026 0.022 16.0 0.4 2 23 729 751 728 751 0.96 17 19 0.00059 0.049 14.9 0.3 1 23 757 780 757 780 0.96 18 19 8.7e-07 7.2e-05 23.8 0.5 1 23 789 811 789 811 0.99 19 19 0.048 4 8.9 0.1 1 23 817 840 817 840 0.89
Sequence Information
- Coding Sequence
- ATGTGCGCCAACGCACGGTCGGAGCAATCTTGCCAAGCCTCGAAACCTGGATGGGACGGAGACGCGGCAGCATCACCTACAGGTAGAACGTACAAGACAGCGTCGGAGATAGTACGGCACGGGAAAGTGCACGACGGCACGGACTACACATGTTCGTATAAGTGCGGATATACCTCTGTGTACAAGCACGCACTGAAGGAGCACGAGAAACGACACCGGAGAGAGCATGCGTACAAATGCAACCAGTGCGGCAAAGGTTTCCATGTGAAGACCTGGTTCGAGCAGCATCAGAATGTGCACGAGAACAAACGGCCTTACAAGTGTGAGCTGTGCGGAGTCGCCTTCCATATGGAcagATATCTTTCGTCGCACCGCAGCACCGTCCACCCGAATGCCACAAAGCAGAACAGATACGTGTGTACCATTTGCACCTACTCCTGCAACTCCAGCCAGAGTCTCGCTTTGCATTTGAAGTACCACGGCGTGAAGAAGGACCTTCTGTGTGACGTATGCGGCAAAGCGATGCGGACAAACAAGCAGCTTAACGTTCACAAGCGGACGCATTTGGGTGTCAAGCCTTACGCTTGCGAAACCTGCAACAAGTCTTTCACAAAGAAATGCCATCTGACGCTGCACGAGAAGTCCACCCATTCCGGGGAGCGACTGCAGTGCACCGCATGCACCAGACTCTTCACACAACTTAGTAGCCTCAACAGGCATATGAGGAGACGACACAAAGAACTAGTGACGCATGTGTGCCCGAAATGTAACAAGATATTACCGACGGACACAGAGTTGATCGCACACGTACAAGAGTGTAAAGTAGTTAAAGCGGACTTCGGGGAATTGGCCTACATTCCATCACCACCGCCACCAGATATGATGCACACGAAAGACGAACCTATGAATCGCGAAGATATAGAAGATATGGAGcTCACAGACTCGACTCTCCAATCAGCAAGAGACCAGTGCCAACTCATAAACCTTAGTAAAGCACAACTGGATATTATTGAGCTGGGAGGCACAGAGGAGCCCAACATTGAAGAATCCTTCTCGGTGACATACAATCGGAGCAGCAATAAGGATGTCATGATCAAACTTGAACTGAAGGAGGACGATAACTTGTTTGTATCGGATCGGGATGCTGATGatgACTTCGATGATAATAACGTGAAAGAAGAAGACGATTTCCCTCTAAAAGATATGTTCAAAGAAGAATTACATGATATCAAAGTTCTCAGCAAGAGTATGAGAAAAATGAAAGGAcagaagaagaaaagaaaaaaagtccGGTCGATAAGTAATACAGAATTTGATGACGACAATGTAAAAGAAGAAGACGATTTTCCATTACTAGAACTGGATGGTATTGACTTGAAAGTCCTAAGAAAAAGTGGCCGAATCAAAGGACCTAAGACTAAAAGTAAGGAAGAGGAATCCACTAACTATACAAAAGATGcgatcaaaataaagaaaatacacATAACTAGGGAGCAATGTATGGAGGAGAGACGAATGTTGGCTCAAGATAAGAAATACCTCAGTTCGGCTTTCAAATGCGAGGATTGCATAAAGGGATTCAATTTCAAGGATTCATATGAGAAACATATGGAGAAACATAGTGAGGCGCGAGGTCCACACGAATGCGATATTTGCAAGTTAAGAGTGGATACAGAAGAGAAATTAATTTGTCACAAGAGATATCATGAATTGCGCTACAAGTGCGGCGAATGCGAGCTGACTCGCGTGTGTCGACTGACCATTAAGGATCACTACACGGCCGTGCATCGGCGCGGTGTGCATCAGTATACGTGTCCCGATTGTCCGAAGACCTTCAACCGTGAGGTGTCTCTCCGCAAGCACACAAGTTACGCGCACCGCGGGCTGGCGCGCGCCGCCTGCGCCCACTGCCCGAAGTCCTACGCCAACAGAGAAGTGCTCAAGGCTCATATGATGCAAAAACATCCAAACGAAGTGACGGCGGAAACAGTGAAGCGTCACGAGTGCGAACACTGCGGATTGTGCTTTAGAGCACCCTCGTTGCTGGTGAAGCACAGCATCAAGCACTCGCTCGTGAGGAGTTACTACTGCGTCGAGTGTGATAAGAGTTTCAAGACTGATTCGGCGTTGAAGCAGCATTTGAAAACTGCGTTGCCTCACATCACCTATGTTGAGTTACCCCTTCAATGCTTATACTGCGAGAAACGTTTCGCGGTGCGTCGCGATGTCGAGCGTCATATGAACCGCGTGCATCTCAACATCAAACCTTACAAGTGTAACCTGTGTGATAAGGCTTACGTGAACGGATGGTCTCTAAACGAACACAAGCGGTTCGCGCACGAAGGCCAGAAAAGACCCCTGAAATATCCCTGTTCTATGTGCGATAAAGTTTTCGATcgGAACCAAACACTGAAAGGCCACATCAGAACTCACACGGGCGAGCGACCGTTTCAATGCACCAAATGCCCCGCCAAGTTCAGCCAAGCGGGCATACTTGGCACGCACGTCAAACTTGTCCATTTGAAACTTACGAGGGACGGCCGACCGAAGACCTTGGCGGTGAAATGA
- Protein Sequence
- MCANARSEQSCQASKPGWDGDAAASPTGRTYKTASEIVRHGKVHDGTDYTCSYKCGYTSVYKHALKEHEKRHRREHAYKCNQCGKGFHVKTWFEQHQNVHENKRPYKCELCGVAFHMDRYLSSHRSTVHPNATKQNRYVCTICTYSCNSSQSLALHLKYHGVKKDLLCDVCGKAMRTNKQLNVHKRTHLGVKPYACETCNKSFTKKCHLTLHEKSTHSGERLQCTACTRLFTQLSSLNRHMRRRHKELVTHVCPKCNKILPTDTELIAHVQECKVVKADFGELAYIPSPPPPDMMHTKDEPMNREDIEDMELTDSTLQSARDQCQLINLSKAQLDIIELGGTEEPNIEESFSVTYNRSSNKDVMIKLELKEDDNLFVSDRDADDDFDDNNVKEEDDFPLKDMFKEELHDIKVLSKSMRKMKGQKKKRKKVRSISNTEFDDDNVKEEDDFPLLELDGIDLKVLRKSGRIKGPKTKSKEEESTNYTKDAIKIKKIHITREQCMEERRMLAQDKKYLSSAFKCEDCIKGFNFKDSYEKHMEKHSEARGPHECDICKLRVDTEEKLICHKRYHELRYKCGECELTRVCRLTIKDHYTAVHRRGVHQYTCPDCPKTFNREVSLRKHTSYAHRGLARAACAHCPKSYANREVLKAHMMQKHPNEVTAETVKRHECEHCGLCFRAPSLLVKHSIKHSLVRSYYCVECDKSFKTDSALKQHLKTALPHITYVELPLQCLYCEKRFAVRRDVERHMNRVHLNIKPYKCNLCDKAYVNGWSLNEHKRFAHEGQKRPLKYPCSMCDKVFDRNQTLKGHIRTHTGERPFQCTKCPAKFSQAGILGTHVKLVHLKLTRDGRPKTLAVK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -